Publications of E050 in 2020
Journal Article
The Phase I/II ACCEPT Trial: Concurrent Cetuximab and Intensity-Modulated Radiotherapy with Carbon Ion Boost for Adenoid Cystic Carcinoma of the Head and Neck: Cetuximab and IMRT/Carbon Ions for ACC.
International journal of radiation oncology, biology, physics 106(1), 167-173 (2020) [10.1016/j.ijrobp.2019.09.036]
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Journal Article
Intrafractional vaginal dilation in anal cancer patients undergoing pelvic radiotherapy (DILANA) - a prospective, randomized, 2-armed phase-II-trial.
BMC cancer 20(1), 52 (2020) [10.1186/s12885-020-6547-7]
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Journal Article
Evaluation of Uterine Brachytherapy as Primary Treatment Option for Elderly Patients with Medically Inoperable Endometrial Cancer-A Single-Center Experience and Review of the Literature.
Cancers 12(8), 2301 (2020) [10.3390/cancers12082301]
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Journal Article
Late contrast enhancing brain lesions in proton treated low-grade glioma patients: clinical evidence for increased periventricular sensitivity and variable RBE.
International journal of radiation oncology, biology, physics 107(3), 571-578 (2020) [10.1016/j.ijrobp.2020.03.013]
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Journal Article
Volume-dependent dose-response of the intestinal stem cell niche and lymphoid tissue.
Radiotherapy and oncology 150, 51 - 56 (2020) [10.1016/j.radonc.2020.06.003]
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Journal Article
Impact of Single Dose Photons and Carbon Ions on Perfusion and Vascular Permeability: A Dynamic Contrast-Enhanced MRI Pilot Study in the Anaplastic Rat Prostate Tumor R3327-AT1.
Radiation research 193(1), 34-45 (2020) [10.1667/RR15459.1]
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Journal Article
High Doses of Photons and Carbon Ions Comparably Increase Vascular Permeability in R3327-HI Prostate Tumors: A Dynamic Contrast-Enhanced MRI Study.
Radiation research 194(5), 465-475 (2020) [10.1667/RADE-20-00112.1]
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Journal Article
Exploring MR regression patterns in rectal cancer during neoadjuvant radiochemotherapy with daily T2- and diffusion-weighted MRI.
Radiation oncology 15(1), 171 (2020) [10.1186/s13014-020-01613-4]
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Journal Article
High-dose carbon-ion based radiotherapy of primary and recurrent sacrococcygeal chordomas: long-term clinical results of a single particle therapy center.
Radiation oncology 15(1), 206 (2020) [10.1186/s13014-020-01647-8]
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Journal Article
Mapping the Relative Biological Effectiveness of Proton, Helium and Carbon Ions with High-Throughput Techniques
Cancers 12(12), 3658 (2020) [10.3390/cancers12123658]
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Journal Article (Review Article)
ESTRO/ACROP IORT recommendations for intraoperative radiation therapy in primary locally advanced rectal cancer
Clinical and translational radiation oncology 25, 29 - 36 (2020) [10.1016/j.ctro.2020.09.001]
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Journal Article
Analysis of a surgical series of 21 cerebral radiation necroses.
World neurosurgery 137, e462-e469 (2020) [10.1016/j.wneu.2020.02.005]
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Journal Article
Carbon Ion Beam Reirradiation in Recurrent High-Grade Glioma
Cancer management and research Volume 12, 633 - 639 (2020) [10.2147/CMAR.S217824]
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Journal Article
Consolidation Immunotherapy After Platinum-Based Chemoradiotherapy in Patients With Unresectable Stage III Non-Small Cell Lung Cancer-Cross-Sectional Study of Eligibility and Administration Rates.
Frontiers in oncology 10, 586449 (2020) [10.3389/fonc.2020.586449]
Fulltext by Pubmed Central
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Journal Article
A matched-pair analysis comparing stereotactic radiosurgery with whole-brain radiotherapy for patients with multiple brain metastases.
Journal of neuro-oncology 147(3), 607-618 (2020) [10.1007/s11060-020-03447-2]
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Journal Article
Single-Isocenter Volumetric Modulated Arc Therapy vs. CyberKnife M6 for the Stereotactic Radiosurgery of Multiple Brain Metastases.
Frontiers in oncology 10, 568 (2020) [10.3389/fonc.2020.00568]
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Journal Article
Stereotactic Cavity Irradiation or Whole-Brain Radiotherapy Following Brain Metastases Resection?Outcome, Prognostic Factors, and Recurrence Patterns
Frontiers in oncology 10, 693 (2020) [10.3389/fonc.2020.00693]
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Journal Article
Pre-clinical evaluation of dual-layer spectral computed tomography-based stopping power prediction for particle therapy planning at the Heidelberg Ion Beam Therapy Center.
Physics in medicine and biology 65(9), 095007 (2020) [10.1088/1361-6560/ab735e]
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Journal Article
T2/FLAIR-mismatch sign for noninvasive detection of IDH-mutant 1p/19q non-codeleted gliomas: validity and pathophysiology.
Neuro-oncology advances 2(1), vdaa004 (2020) [10.1093/noajnl/vdaa004]
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Journal Article (Review Article)
Accelerated Partial Breast Irradiation: A New Standard of Care?
Breast care 15(2), 136 - 147 (2020) [10.1159/000506254]
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Journal Article
Fatigue following radiotherapy of low-risk early breast cancer - a randomized controlled trial of intraoperative electron radiotherapy versus standard hypofractionated whole-breast radiotherapy: the COSMOPOLITAN trial (NCT03838419).
Radiation oncology 15(1), 134 (2020) [10.1186/s13014-020-01581-9]
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Journal Article
Adjuvant Radiation Therapy for Male Breast Cancer?A Rare Indication?
Cancers 12(12), 3645 (2020) [10.3390/cancers12123645]
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Contribution to a conference proceedings
Comparison of tumor autosegmentation techniques from an undersampled dynamic radial bSSFP acquisition on a low-field MR-linac.
International Society for Magnetic Resonance in Medicine, OnlineOnline, Online, 18 Apr 2020 - 23 Apr 2020
27, 1138 pp. (2020) special issue: "Proc. Intl. Soc. Mag. Reson. Med."
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Journal Article
Towards a generalised development of synthetic CT images and assessment of their dosimetric accuracy.
Acta oncologica 59(2), 180-187 (2020) [10.1080/0284186X.2019.1684558]
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Journal Article
Carbon ion reirradiation compared to intensity-modulated re-radiotherapy for recurrent head and neck cancer (CARE): a randomized controlled trial.
Radiation oncology 15(1), 190 (2020) [10.1186/s13014-020-01625-0]
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Journal Article
Cone-Beam-CT Guided Adaptive Radiotherapy for Locally Advanced Non-small Cell Lung Cancer Enables Quality Assurance and Superior Sparing of Healthy Lung.
Frontiers in oncology 10, 564857 (2020) [10.3389/fonc.2020.564857]
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Journal Article
First prospective clinical evaluation of feasibility and patient acceptance of magnetic resonance-guided radiotherapy in Germany.
Strahlentherapie und Onkologie 196(8), 691-698 (2020) [10.1007/s00066-020-01578-z]
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Journal Article
An R package for an integrated evaluation of statistical approaches to cancer incidence projection.
BMC medical research methodology 20(1), 257 (2020) [10.1186/s12874-020-01133-5]
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Journal Article
The Role of 68Ga-FAPI PET/CT for Patients with Malignancies of the Lower Gastrointestinal Tract: First Clinical Experience.
Journal of nuclear medicine 61(9), 1331 - 1336 (2020) [10.2967/jnumed.119.237016]
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Journal Article
Lymph node involvement in treatment-naïve prostate cancer patients - correlation of PSMA-PET/CT imaging and Roach formula in 280 men in the Radiotherapeutic management.
Journal of nuclear medicine 61(1), 46-50 (2020) [10.2967/jnumed.119.227637]
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Journal Article
Stereotactic body radiotherapy (SBRT) for adrenal metastases of oligometastatic or oligoprogressive tumor patients.
Radiation oncology 15(1), 30 (2020) [10.1186/s13014-020-1480-0]
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Journal Article
Secondary Malignancy Risk Following Proton vs. X-ray Treatment of Mediastinal Malignant Lymphoma: A Comparative Modeling Study of Thoracic Organ-Specific Cancer Risk
Frontiers in oncology 10, 989 (2020) [10.3389/fonc.2020.00989]
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Journal Article
Development and validation of single field multi-ion particle therapy treatments.
International journal of radiation oncology, biology, physics 106(1), 194-205 (2020) [10.1016/j.ijrobp.2019.10.008]
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Journal Article
FRoG: An independent dose and LETd prediction tool for proton therapy at ProBeam® facilities.
Medical physics 47(10), 5274-5286 (2020) [10.1002/mp.14417]
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Journal Article
Percutaneous Endoscopic Gastrostomy Tube Placement in Patients with Head and Neck Cancer Treated with Radiotherapy
Cancer management and research Volume 12, 127 - 136 (2020) [10.2147/CMAR.S218432]
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Journal Article (Review Article)
Carbon ion radiotherapy in pancreatic cancer: A review of clinical data.
Radiotherapy and oncology 147, 145 - 150 (2020) [10.1016/j.radonc.2020.05.012]
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Journal Article (Erratum/Correction)
Carbon ion radiotherapy as definitive treatment in non-metastasized pancreatic cancer: study protocol of the prospective phase II PACK-study.
BMC cancer 20(1), 947 (2020) [10.1186/s12885-020-07434-8]
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Journal Article
Stereotactic Radiosurgery With Concurrent Immunotherapy in Melanoma Brain Metastases Is Feasible and Effective
Frontiers in oncology 10, 592796 (2020) [10.3389/fonc.2020.592796]
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Journal Article
Modeling Direct and Indirect Action on Cell Survival After Photon Irradiation under Normoxia and Hypoxia
International journal of molecular sciences 21(10), 3471 (2020) [10.3390/ijms21103471]
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Journal Article
Dosimetric Impact of the Positional Imaging Frequency for Hypofractionated Prostate Radiotherapy ? A Voxel-by-Voxel Analysis
Frontiers in oncology 10, 564068 (2020) [10.3389/fonc.2020.564068]
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Journal Article
Design and Development of 99m Tc-Labeled FAPI Tracers for SPECT Imaging and 188 Re Therapy
Journal of nuclear medicine 61(10), 1507 - 1513 (2020) [10.2967/jnumed.119.239731]
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Journal Article
Assessment of RBE-weighted dose models for carbon ion therapy towards modernization of clinical practice at HIT: in vitro, in vivo and in patients.
International journal of radiation oncology, biology, physics 108(3), 779-791 (2020) [10.1016/j.ijrobp.2020.05.041]
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Dissertation / PhD Thesis
FRoG: a fast robust analytical dose engine on GPU for p, 4He, 12C and 16O particle therapy
Dissertation, Universität Heidelberg, 2020[10.11588/HEIDOK.00027888]
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Journal Article
Radiographic Response of Vessel Involvement and Resectability After Neoadjuvant Chemoradiation in Patients With Locally Advanced Pancreatic Cancer.
American journal of clinical oncology 43(11), 776-783 (2020) [10.1097/COC.0000000000000746]
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Journal Article
Feasibility of Optical Surface-Guidance for Position Verification and Monitoring of Stereotactic Body Radiotherapy in Deep-Inspiration Breath-Hold
Frontiers in oncology 10, 573279 (2020) [10.3389/fonc.2020.573279]
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Journal Article
Personalized Assessment of Normal Tissue Radiosensitivity via Transcriptome Response to Photon, Proton and Carbon Irradiation in Patient-Derived Human Intestinal Organoids
Cancers 12(2), 469 (2020) [10.3390/cancers12020469]
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Contribution to a conference proceedings
Sodium MRI at 7 Tesla as quantitative biomarker to assess tumor heterogeneity and histologic subtypes in glioma patients.
International Society for Magnetic Resonance in Medicine, OnlineOnline, Online, 18 Apr 2020 - 23 Apr 2020
27, 0402 pp. (2020) special issue: "Proc. Intl. Soc. Mag. Reson. Med."
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Journal Article
Ultra-high-field sodium MRI as biomarker for tumor extent, grade and IDH mutation status in glioma patients
NeuroImage: Clinical 28(1), 102427 (2020) [10.1016/j.nicl.2020.102427]
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Journal Article
Progression of Pulmonary Function and Correlation with Survival Following Stereotactic Body Radiotherapy of Central and Ultracentral Lung Tumors.
Cancers 12(10), 2862 (2020) [10.3390/cancers12102862]
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Journal Article
Impact of Primary Staging with Fibroblast Activation Protein Specific Enzyme Inhibitor (FAPI)-PET/CT on Radio-Oncologic Treatment Planning of Patients with Esophageal Cancer.
Molecular imaging and biology 22(6), 1495-1500 (2020) [10.1007/s11307-020-01548-y]
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Journal Article
Fractionated carbon ion irradiations of the rat spinal cord: comparison of the relative biological effectiveness with predictions of the local effect model.
Radiation oncology 15(1), 6 (2020) [10.1186/s13014-019-1439-1]
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Journal Article
Ramipril reduces incidence and prolongates latency time of radiation-induced rat myelopathy after photon and carbon ion irradiation.
Journal of radiation research 61(5), 791-798 (2020) [10.1093/jrr/rraa042]
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Journal Article (Review Article)
Particle therapy in the future of precision therapy.
BJR 93(1114), 20200183 (2020) [10.1259/bjr.20200183]
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Journal Article
Comparison of GeneChip, nCounter and real-time polymerase chain reaction based gene expressions predicting loco-regional tumour control after primary and postoperative radiochemotherapy in head and neck squamous cell carcinoma.
The journal of molecular diagnostics 22(6), 801-810 (2020) [10.1016/j.jmoldx.2020.03.005]
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Journal Article
Radiation-induced alterations in immunogenicity of a murine pancreatic ductal adenocarcinoma cell line.
Scientific reports 10(1), 686 (2020) [10.1038/s41598-020-57456-2]
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Journal Article
Methods of spatial cluster detection in rare childhood cancers: Benchmarking data and results from a simulation study on nephroblastoma
Data in Brief 34, 106683 (2021) [10.1016/j.dib.2020.106683]
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Journal Article
Radiotherapy in the treatment of aggressive fibromatosis: experience from a single institution.
Radiation oncology 15(1), 143 (2020) [10.1186/s13014-020-01565-9]
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Journal Article (Review Article)
Re-irradiation with protons or heavy ions with focus on head and neck, skull base and brain malignancies.
The British journal of radiology 93(1107), 20190516 (2020) [10.1259/bjr.20190516]
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Journal Article
Die Einführung eines permanenten Erhebungssystems zur Messung der Lebensqualität von HNO-Patienten an der Klinik für Strahlentherapie am Universitätsklinikum Freiburg: Implementierungsbericht
Gesundheitso?konomie & Qualita?tsmanagement 25(04), 195 - 200 (2020) [10.1055/a-1119-8233]
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Journal Article
Fibroblast activation protein inhibitor (FAPI) PET for diagnostics and advanced targeted radiotherapy in head and neck cancers.
European journal of nuclear medicine and molecular imaging 47(12), 2836-2845 (2020) [10.1007/s00259-020-04859-y]
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Journal Article
Carbon ion dosimetry on a fluorescent nuclear track detector using widefield microscopy.
Physics in medicine and biology 65(21), 21NT02 (2020) [10.1088/1361-6560/abb7c5]
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Journal Article
Age-dependent hemato- and nephrotoxicity in patients with head and neck cancer receiving chemoradiotherapy with weekly cisplatin.
Strahlentherapie und Onkologie 196(6), 515-521 (2020) [10.1007/s00066-019-01550-6]
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Journal Article
Extracranial Stereotactic Body Radiotherapy in Oligometastatic or Oligoprogressive Breast Cancer.
Frontiers in oncology 10, 987 (2020) [10.3389/fonc.2020.00987]
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Journal Article
Validation of Nine Different Prognostic Grading Indexes for Radiosurgery of Brain Metastases in Breast Cancer Patients and Development of an All-Encompassing Prognostic Tool
Frontiers in oncology 10, 1557 (2020) [10.3389/fonc.2020.01557]
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Journal Article
Fibroblast Activation Protein (FAP) specific PET for advanced target volume delineation in glioblastoma.
Radiotherapy and oncology 150, 159 - 163 (2020) [10.1016/j.radonc.2020.06.040]
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Journal Article (Review Article)
Clinical Results of Fibroblast Activation Protein (FAP) Specific PET and Implications for Radiotherapy Planning: Systematic Review.
Cancers 12(9), 2629 (2020) [10.3390/cancers12092629]
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Journal Article
Interprofessionelle Kooperation in klinischen Studien
Klinikarzt 49(01/02), 39 - 46 (2020) [10.1055/a-1096-9216]
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Journal Article
Lack of Relevant Haemogram Changes During Percutaneous Radiotherapy of Localised Prostate Cancer.
In vivo 34(3), 1555 - 1563 (2020) [10.21873/invivo.11945]
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