Selected Publications

1. Schifflers, C., Zottnick, S., Förster, J.D., Kruse, S., Yang, R., Wiethoff, H., Bozza, M., Hoppe-Seyler, K., Heikenwälder, M. and Harbottle, R.P. (2023) Development of an Orthotopic HPV16-Dependent Base of Tongue Tumor Model in MHC-Humanized Mice. Pathogens, 12, 188.

2. Roig-Merino, A., Urban, M., Bozza, M., Peterson, J.D., Bullen, L., Büchler-Schäff, M., Stäble, S., van der Hoeven, F., Müller-Decker, K. and McKay, T.R. (2022) An episomal DNA vector platform for the persistent genetic modification of pluripotent stem cells and their differentiated progeny. Stem Cell Reports, 17, 143-158.

3. Hongu, T., Pein, M., Insua-Rodriguez, J., Gutjahr, E., Mattavelli, G., Meier, J., Decker, K., Descot, A., Bozza, M., Harbottle, R., et al (2022) Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs. Nature Cancer, 3, 486-504.

4. Chan, T., Grisch-Chan, H.M., Schmierer, P., Subotic, U., Rimann, N., Scherer, T., Hetzel, U., Bozza, M., Harbottle, R. and Williams, J.A. (2022) Delivery of non-viral naked DNA vectors to liver in small weaned pigs by hydrodynamic retrograde intrabiliary injection. Molecular Therapy-Methods & Clinical Development, 24, 268-279.

5. Thornton, C.D., Fielding, S., Karbowniczek, K., Roig-Merino, A., Burrows, A.E., FitzPatrick, L.M., Sharaireh, A., Tite, J.P., Mole, S.E. and Harbottle, R.P. (2021) Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors. Molecular Therapy-Methods & Clinical Development, 23, 348-358.

6. Bozza, M., De Roia, A., Correia, M.P., Berger, A., Tuch, A., Schmidt, A., Zörnig, I., Jäger, D., Schmidt, P. and Harbottle, R.P. (2021) A nonviral, nonintegrating DNA nanovector platform for the safe, rapid, and persistent manufacture of recombinant T cells. Science advances, 7, eabf1333.

7. Yang, T., Heydarian, M., Kozjak-Pavlovic, V., Urban, M., Harbottle, R.P. and Rudel, T. (2020) Folliculin Controls the Intracellular Survival and Trans-Epithelial Passage of Neisseria gonorrhoeae. Frontiers in Cellular and Infection Microbiology, 10, 422.

8. Ali, D., Zepp, M., Bozza, M., Nikolova, M., Harbottle, R. and Berger, M.R. (2020) Ly6-neurotoxin1 knockout in PDAC cells inhibits their growth in vitro and in vivo. Cancer Research, 80, 4717-4717.

9. Viarisio, D., Müller-Decker, K., Accardi, R., Robitaille, A., Dürst, M., Beer, K., Jansen, L., Flechtenmacher, C., Bozza, M. and Harbottle, R. (2018) Beta HPV38 oncoproteins act with a hit-and-run mechanism in ultraviolet radiation-induced skin carcinogenesis in mice. PLoS pathogens, 14, e1006783.

10. Bunse, L., Pusch, S., Bunse, T., Sahm, F., Sanghvi, K., Friedrich, M., Alansary, D., Sonner, J.K., Green, E. and Deumelandt, K. (2018) Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate. Nature medicine, 24, 1192-1203.