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Major Cancer Biology Students 2024

Nations Unite at DKFZ - Welcome to the Students of Major Cancer Biology 2024!

The new students were officially welcomed and introduced to the DKFZ on 14th October 2024 by the Director of the Cancer Research Academy, Prof. Duncan Odom, and by the Scientific Coordinator, Prof. Ilse Hofmann.
© dkfz.de

24 students from all around the world have joined the Heidelberg University international masters program Molecular Biosciences for their studies in Major Cancer Biology at DKFZ Heidelberg. During the Welcome Events in October 2024 we asked them for their expectations for this new chapter in their career.
© dkfz.de

Apoorva BHAT (India)

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University Education
10/2024 – present: M.Sc. in Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls University and German Cancer Research Center (DKFZ), Heidelberg, Germany
12/2020 – 06/2024: Bachelor of Technology (B.Tech) in Biotechnology, PES University, Bangalore, India

Highest Degree: Bachelor of Technology (B.Tech) in Biotechnology
Title of Bachelor's Thesis: Role of the human gut microbiome in the control of sepsis

Internships/Work Experience:
01/2024 – 06/2024: Research internship at AR Lab, Department of Developmental Biology and Genetics, Indian Institute of Science (IISc), Bangalore, India. I explored the role of the AMPK-HIF-1α loop in regulation of survival and metabolism of matrix-deprived triple-negative breast cancer cells.
06/2023 – 07/2023: Summer internship at Zumutor Biologics, Bangalore, India. I learnt and performed molecular biology, cellular biology, and protein purification techniques.
07/2022 – Summer internship at DIA Lab, Centre for Cellular and Molecular Platforms (C-CAMP), Bangalore, India. I worked on the purification of a recombinant protein from a bacterial expression system.

Scientific Interests & Future Plans
During my undergraduate studies I was introduced to the concept of translating science into medicine through courses like molecular biology, cancer biology, and immunology. Cancer, as a group of diseases, has always piqued my interest owing to its complexity. My interest in cancer biology further solidified during my internship at IISc. Cancer stem cells (CSCs) exhibit self-renewal properties along with chemoresistance and are responsible for the relapse of cancer. Targeting CSCs is thus considered to be a promising therapeutic target. Having worked on the metabolic regulation of TNBCs, I am curious to learn about CSCs and the mechanisms that control cancer progression. I am also interested in exploring the opportunities within immuno-oncology. As a major cancer biology student at DKFZ, I look forward to making a valuable impact in the fight against cancer.

Contact: apoorva.bhat (at) dkfz.de
LinkedIn profile

Lilli BÖHLING (Germany)

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University Education
10/2024 – present: M. Sc. in Molecular Biosciences - Major Cancer Biology, Ruprecht-Karls-University and German Cancer Research Center (DKFZ), Heidelberg, Germany
10/2020 – 09/2023: B. Sc. in Biomedical Science – Major Cancer Biology, Philipps-University-Marburg, Germany
10/2018 – 10/2020: Training as a biological technician assistant (BTA), Hochschule Fresenius (Idstein) in cooperation with BioNTech SE (Mainz), Germany

Highest Degree: B. Sc. in Biomedical Science
Bachelor's Dissertation: Implications of ovarian cancer specific basal cell adhesion molecule (BCAM) overexpression for chemoresistance

Internships/Work Experience
08/2022 & 02/2023 – 07/2023: Research internship and bachelor thesis at the research group of Dr. Rolf Müller at the Center of Tumor Biology and Immunology (ZTI) in Marburg
04/2022 – 07/2023: Student Assistant at Philipps-University Marburg; Supervision of biochemical and molecular biological laboratory practicals for medical & biomedical students
07/2019 – 08/2019 & 01/2020 – 02/2020: Internship at BioNTech SE at the research group of Dr. Christiane Stadler; Project: Development of cancer target directed, T-Cell engaging bispecific antibodies

Scientific Interests & Future Plans
My interest in science began early in school, but it was my apprenticeship at BioNTech SE that truly strengthened my passion for cancer research. I was particularly inspired by the company's innovative approach to linking tumor control with the patient's own immune system. I am looking forward to deepening my understanding of the interactions between cancer formation, progression, and the immune system at the DKFZ. My bachelor thesis then shifted my focus specifically to cancers that primarily affect women, such as breast and ovarian cancer, highlighting the need for more research targeting females, as it has fallen short for many decades. I am excited about the opportunity to contribute to the research at DKFZ, working towards the goal of "a life without cancer." I believe that the Molecular Biosciences Master's program will be a crucial milestone in my journey, guiding me toward a PhD and enabling me to make meaningful advancements in this vital field of cancer research.

Contact: lillimarie.boehling (at) dkfz.de
LinkedIn profile

Julia CREMER (Germany)

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University Education
10/2024 – present: M.Sc. in Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls University and German Cancer Research Centre (DKFZ), Heidelberg, Germany
10/2021 – 09/2024: B.Sc. in Biomedical Sciences – Major Tumor Biology, Philipps-Universität Marburg, Marburg, Germany

Highest Degree: Bachelor of Science (B.Sc.) in Biomedical Sciences
Title of Bachelor Thesis: CRISPR Knockout of Protein Arginine Methyltransferases in Small Cell Lung Cancer

Internships/Work Experience
02/2024 – 09/2024: Research internship and Bachelor thesis at the Centre of Tumor Biology and Immunology, Institute of Molecular Oncology (Prof. Dr. Thorsten Stiewe), Marburg, Germany
04/2023 – 08/2023 and 10/2023 – 02/2024: Student Assistant at internship "Biochemistry/Molecular Biology for students of Human Medicine and Dentistry"
10/2022 – 03/2023 and 10/2023 – 02/2024: Leader of a tutorial "Mathematics for students of Human Biology"

Scientific Interests & Future Plans
Motivated by the desire to contribute to the continuous fight against cancer, I am eager to understand how genetic mutations can drive the development of cancer. The impact that small alterations in specific genes can have on cellular processes, leading to uncontrolled cell growth and tumor formation is impressive. Looking ahead, I want to delve deeper into genomic research to uncover potential targets for therapeutic intervention and more personalized cancer treatments. Furthermore, I am interested in the tumor microenvironment and its potential for influencing therapeutic outcomes. By exploring the interactions between cancer cells and the surrounding tissue, I aim to contribute to the development of innovative treatments that target not just the tumor itself, but its supportive environment.

Contact: julia.cremer (at) dkfz.de
LinkedIn profile

Antonia EHRING (Germany)

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University Education
10/2024 – present: M.Sc. in Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls University and German Cancer Research Center (DKFZ), Heidelberg, Germany
10/2020 – 05/2024 B.Sc. in Molecular Medicine, Friedrich-Alexander University Erlangen, Germany

Highest Degree: Bachelor of Science in Molecular Medicine
Title of Bachelor's Thesis: „Molecular-biological investigation of a new luciferase reporter-expressing cytomegalovirus for the identification of antiviral compounds"

Internships/Work Experience
10/2024 – present: Research assistant at center for clinical studies, Thoraxklinik, Heidelberg University Hospital, Germany
06/2024 – 08/2024 Internship at Cambridge Institute for Medical Research, Research group Prof. Weekes (HCMV and MPXV), Cambridge, UK
08/2023 – 01/2024 & 03/2024 – 05/2024 Bachelor's thesis and research assistant at the Institute of Clinical and Molecular Virology, Research group Prof. Marschall (HCMV and antiviral compounds), University Hospital Erlangen, Germany
11/2022 – 01/2024 Student assistant at the HLA/Immunogenetics Laboratory (Organ donation diagnostics for Eurotransplant and DSO), University Hospital Erlangen, Germany
08/2020 – 10/2020 Student assistant at Bavarian Nordic GmbH (Regulatory Affairs Department), Martinsried, Germany

Publication
Tillmanns J*, Kicuntod J*, Ehring A*, Elbasani E, Borst EM, Obergfäll D, Müller R, Hahn F, Marschall M. Establishment of a Luciferase-Based Reporter System to Study Aspects of Human Cytomegalovirus Infection, Replication Characteristics, and Antiviral Drug Efficacy. Pathogens. 2024 Jul 31;13(8):645. doi: 10.3390/pathogens13080645. PMID: 39204245; PMCID: PMC11356942. *equal contribution

Scientific Interests & Future Plans
The complexity of molecular biological processes has always fascinated me and was my main reason for pursuing medical research as a career. I'm especially interested in how changes in essential cellular mechanisms can lead to formation of cancer with its unique characteristics. My goal is to contribute to research in this area that may lead to the development of innovative therapies or diagnostics. So far, I have done a lot of work with viruses, and I plan to apply this knowledge when working on tumor-associated viruses or oncolytic viruses. However, I want to gain insight into as many aspects of cancer research as possible during my Master's studies and I'm always open to other interesting or exciting aspects of cancer biology.

Contact: antonia.ehring (at) dkfz.de

Edvardas EIGMINAS (Lithuania)

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University Education
2020-2024 - The University of Edinburgh - BSc Hons Biological Sciences (Immunology)

Highest Degree: BSc Hons
Title of Bachelor's Thesis: Can phosphatases reduce Plasmodium falciparum host-parasite adhesion in severe malaria?

Internships/Work Experience
(2023.05-2023.11) The University of Edinburgh, Member of iGEM 2023 team: Genetically engineering cyanobacteria (Synechocystis spp) for increased extracellular electron transfer and nutrient production with potential application in biophotovoltaic pollinator-friendly solar panels. In a team of 12 students, I led the biosafety sub-project which involved building a nuclease-based genetic kill switch in cyanobacteria to control the spread of GMOs in the environment.
(05.2022-07.2022) The University of Edinburgh, Research Intern at Philip Research Group: Working on the intracellular cyclic nucleotide signalling important during transmission stages of Plasmodium parasite. I successfully cloned and expressed predicted cyclic nucleotide-binding domains of the EPAC protein in E. coli. These proteins were later used for further functional analyses to determine their affinity to cyclic AMP and cyclic GMP.
(06.2018-07.2018) Intern at Northway Biotechpharma, Vilnius, Lithuania: While still in high school, I did an internship in a biotechnological company, where I was introduced to biotechnological processes, including harvesting, protein purification at different scales using various chromatography techniques, and refolding process development. I got acquainted with cloning and sequencing of targeted genes and genetic engineering methods for development of expression systems in various cell cultures.

Scientific Interests & Future Plans
During my BSc degree in Biological Sciences (Immunology) at the University of Edinburgh, I became increasingly fascinated by the complexity of the immune system and its crucial role in a variety of diseases, including cancer. My particular interests lie at the interplay of the immune response and cancer development and treatment. Specifically, I am interested how tumours avoid/suppress immune responses and how current immunotherapies (e.g., CAR-T cells, checkpoint inhibitors) can be improved and novel immunotherapies developed for better cancer treatment. My other interests include infection biology, especially malaria parasite trasmission and adhesion to human cells. I am motivated to pursue a career in research with a focus on cancer immunology and contribute towards tackling some of the outstanding challenges. This aligns well with my general academic goal of contributing towards improving people's health and reducing suffering.

Contact: edvardas.eigminas (at) dkfz.de
LinkedIn profile

Nima ESMAEELPOUR (Germany)

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University Education
10/2024 – Present: M.Sc. Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls-University Heidelberg and German Cancer Research Center (DKFZ), Germany
10/2021 – 09/2024: B.Sc. Biology, LMU Munich, Germany
10/2016 – 03/2021: B.Sc. Computer Science, Hochschule Darmstadt, Germany

Highest Degrees
Bachelor of Science in Biology
Bachelor of Science in Computer Science

Title of Bachelor's Theses
Elucidating epigenetic regulation of immunosuppressive PDAC subtype secretomes via Perturb-seq
Reducing Anti-Patterns for Delivering and Deploying Software Continuously in an Open Source Project

Internships/Work Experience
03/2024 – 09/2024: Research Internship and Bachelor's Thesis (Saur Lab), Rechts der Isar Hospital of the Technical University of Munich at TranslaTUM's Institute of Translational Cancer Research and Experimental Cancer Therapy, Germany
07/2022 – 03/2024: Academic Tutor, LMU Munich, Germany
04/2022 – 07/2023: Student Research Assistant (Osman Lab), LMU Munich, Germany
11/2019 – 03/2022: Junior Software Engineer, Telespazio Germany GmbH, Darmstadt, Germany

Scientific Interests & Future Plans
I am a former computer science graduate who found his true passion in biology and graduated from LMU with a Bachelor's degree in biology as the top performing student. I did my Bachelor's thesis at TranslaTUM emplyoying the Perturb-seq method to unveil transcriptional networks controlling the immunosuppressive secretome of pancreatic cancer subtypes. Personally, I find it very interesting to understand chemotherapy-resistant and immune-evading cancer cells and to find new methods to attack and destroy them.
Ironically, I recently have been diagnosed with cancer myself (Hodgkin's lymphoma) and am now fighting this terrible but fascinating disease as both a researcher and a patient, hoping to win on both fronts.

Contact. nima.esmaeelpour (at) dkfz.de
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Paula FELDT (Germany)

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University Education
10/2024 – present: M.Sc. in Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls-University Heidelberg and German Cancer Research Center (DKFZ), Germany
10/2020 - 09/2024 - B.Sc. in Molecular Biology, University of Duisburg-Essen, Germany

Highest Degree: B.Sc. in Molecular Biology
Title of Bachelor's Thesis: Investigating the effect of metabolic modulators on non-small cell lung cancer (NSCLC) cells with distinct metastatic abilities.

Internships/Work Experience
08/2023 - 09/2024: Student Aid (HiWi) and Bachelor's Thesis at the University Hospital Essen, Research Group Cell Plasticity and Metastasis, Prof. Dr. Barbara Grüner, Essen, Germany

Scientific Interests & Future Plans
During my Bachelor's Thesis, I developed a strong passion for cancer research, with a particular focus on metastasis - the leading cause of cancer-related death. My experience working in a lab specialized in cell plasticity and metastasis allowed me to delve into the underlying mechanisms driving this process, further deepening my fascination with how cancer cells spread, adapt, and resist treatment.
As a Cancer Biology student at the DKFZ, I am eager to not only expand my knowledge of metastasis, but also to broaden my knowledge of cancer biology in all its facets. I am particularly driven to explore novel therapeutic strategies for advanced-stage cancers, where treatment options are limited, and patient outcomes remain poor. My ultimate goal is to contribute to innovative, targeted approaches that effectively target metastatic disease, to improve both survival rates and the quality of life for patients with advanced cancers.

Contact: paula.feldt (at) dkfz.de
LinkedIn profile

Paula GARCIA PACHECO (Spain)

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University Education
10/2024 - present: M. Sc. in Molecular Biosciences - Major Cancer Biology, Ruprecht-Karls-University and German Cancer Research Center (DKFZ), Heidelberg, Germany
09/2020 - 06/2024: B. Sc. in Human Biology, Pompeu Fabra University, Barcelona, Spain

Highest Degree: B. Sc. in Human Biology
Title of Bachelor's Thesis: Differential Secretion of Leukemia Inhibitory Factor in Cancer: Elucidating its Regulation by Nuclear Factor Kappa B Signaling Pathway in Glioblastoma and Prostate Adenocarcinoma

Internships/Work Experience
07/2024 - 09/2024: CICERONE program participant at the Spanish National Cardiovascular Research Centre (CNIC). Hematovascular Pathophysiology Group, PI Dr. José Javier Fuster. Conducted research on the interplay between clonal hematopoiesis and the development of atherosclerotic cardiovascular diseases.
04/2024 - 06/2024: Research internship and bachelor's thesis at the Vall d'Hebron Institute of Oncology (VHIO). Gene Expression and Cancer Group, PI Dr.Prof. Joan Seoane.
09/2023: Internship at the Institute of Biomedical Research of Barcelona (CSIC). Neurobiology Group, PI Dr. Ramon Trullàs. Conducted research on uncovering the role of mitochondrial DNA quality control in neurodegeneration.
04/2023 - 07/2023: Internship at the University of Helsinki. Metabolism and Signaling Group, PI Dr. Jaakko Mattila. Conducted research on the role of Nuclear Transcription Factor Y Subunit Alpha (NF-YA) in tissue size regulation and cell apoptosis in Drosophila melanogaster.
10/2022 - 03/2023: Student assistant at Pompeu Fabra University. Supported the preparation of laboratory practicals for biomedical bachelor students as a lab technician.

Scientific Interests & Future Plans
At sixteen, I came across the number of 1 in 10 to the 2,685,000 power, that is believed to represent the odds of you existing today. Then, throughout my bachelor's, I realized how incredibly intertwined the molecular mechanisms that sustain life are and how even minor dysregulations can lead to diseases like cancer, one of the most complex, prevalent, and intellectually challenging diseases of our modern society. So I can't help but wonder: What are the odds of being both alive and healthy like I am? This thought inspired me to pursue a career in cancer research for the improvement of scientific knowledge and, most importantly, people's lives. Now, as a master's student at DKFZ, my goals are to deepen my understanding of translational cancer research and explore some personal interests like intratumoral and tumor microenvironment heterogeneity, a key factor in drug resistance, and the use of the immune system in emerging immunotherapies.

Contact: paula.garciapacheco (at) dkfz.de

Anushri GUPTA (India)

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University Education
10/2024 - present: M.Sc. in Molecular Biosciences – Major Cancer Biology, German Cancer Research Center (DKFZ) and Ruprecht-Karls-University Heidelberg, Germany
11/2020 - 06/2024: Bachelor of Technology (B.Tech) in Biotechnology – Heritage Institute of Technology, Kolkata, India (in affiliation with Maulana Abul Kalam Azad University of Technology)

Highest Degree: Bachelor of Technology (B.Tech) in Biotechnology
Title of Thesis: Immobilization of sucrase isolated from a natural source: Optimization by Response Surface Methodology

Internships/Work Experience
01/06/2024 - 30/06/2024: Research training at the Cancer Biology lab in the School of Medical Science & Technology (SMST) of Indian Institute of Technology, Kharagpur (IIT KGP), under the guidance of Prof. Mahitosh Mandal, to observe and learn techniques used in Cancer research
19/06/2023 - 28/07/2023: Summer research intern at the New Jersey Institute of Technology (NJIT), USA, under the guidance of Prof. Vivek A. Kumar, to assist with the biomedical imaging and data analysis section of a then-ongoing project on "Evaluation of hydrogel scaffolds for myocardial regeneration"
01/2023 - 12/2023: Participated in a project under the guidance of Prof. Nandan Kumar Jana (Heritage Institute of Technology, Kolkata, India) on In silico drug designing against Breast Cancer
13/11/2021 - 04/07/2022: Undergraduate research trainee at Saroj Gupta Cancer Centre & Research Institute (SGCCRI), Thakurpukur, Kolkata, India, under the guidance of Prof. Somsubhra Nath, to learn basic Cancer research laboratory techniques and assist with a project on "Exploring the correlation between CDC20 and UBCH10 in primary oral malignancies"

Publication
A. Gupta, S. Patel, A. Roy and V. Kumar, "Evaluation of Hydrogel Scaffolds for Myocardial Regeneration." Book of Abstracts, 2023 URI Summer Research and Innovation Symposium, pp. 17, New Jersey Institute of Technology, Newark, NJ, USA, July 26-27, 2023.

Scientific Interests & Future Plans
Even though I am yet to learn more about research on Cancer, just because it is an ever-evolving and continuously updating field of research, I know I want to discover more about the role of the environment (the tumour microenvironment or TME) in which the cancerous tumours exist, in assisting the growth, proliferation and thriving of these tumours. Not only the characteristics or changes in nature of the tumour cells are of importance, but also the environment which also plays a critical role, often adapting under the influence of cancer cells to support further development. It's fascinating how the TME can be 'reprogrammed' to allow this disease to thrive. I would like to learn more about these TMEs and hope to discover new and efficient ways to control it, so that it could resist the growth of tumours.

Contact: anushri.gupta (at) dkfz.de

Oskar HAEBERLEIN (Sweden & USA)

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University Education
10/2024 – present: M.Sc. in Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls University and German Cancer Research Center (DKFZ), Heidelberg, Germany
09/2020 – 12/2023: B.Sc. in Biochemistry, University of Washington, Seattle, USA

Highest Degree: Bachelor of Science (B.Sc.) in Biochemistry

Internships/Work Experience
01/2024 – 09/2024: Biomed X Institute, Heidelberg, Germany. Oncological research team EDC: Extrachromosomal DNA in Cancer with Dr. Büşra Yağabasan and Dr. Alexandros Drainas.
06/2022-08/2022: Alkermes, Waltham MA. Protein therapeutics group in the Drug Discovery department.
03/2021 – 06/2022: Imaizumi lab, University of Washington Biology Department: Exploring seasonal flowering mechanisms at the molecular level.

Scientific Interests & Future Plans
Growing up I have always gravitated towards science because of its definitive answers. My curiosity drives me towards understanding life at the molecular level, where so much is still unknown. Modern cancer research requires the most cutting-edge techniques to understand the complex biology behind it. Doing cancer research, therefore, offers a deep dive into many molecular mechanisms in life while simultaneously being applicable to the big picture of improving human health. This is why I am excited and grateful to be here at DFKZ, and to be able to take part in cancer research in the future. I aim to help gain insights on the genomic alterations that occur as cancer progresses and evolves, and to leverage these insights to help combat treatment resistance in patients.

Contact: oskar.haeberlein (at) dkfz.de
LinkedIn profile

Victoria HONEKAMP (Germany)

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University Education
10/2024 – present: M. Sc. in Molecular Biosciences - Major Cancer Biology, Ruprecht-Karls-University and German Cancer Research Center (DKFZ), Heidelberg, Germany
10/2021 – 09/2024: B. Sc. in Biomedical Science - Focus Cancer Biology, Philipps-University Marburg, Germany

Highest Degree: B. Sc. in Biomedical Science
Title of the Bachelor's Thesis: CRISPR/Cas9-mediated targeting of Prmts in murine SCLC

Internships/Work Experience
11/2024 – present: Student assistant (HiWi) at the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM GmbH), Department of Experimental Haematology (Dr. Michael Milsom).
08/2023 & 02/2024 – 08/2024: Research internship and Bachelor thesis at the research group of Prof. Dr. Uta-Maria Bauer at the Institute of Microbiology and Tumor Research at the Philipps-University Marburg.
11/2023 & 04/2024 – 06/2024: Student assistant at the Philipps University of Marburg; supervision and guidance of lessons and laboratory practicals in the subjects of histology, epigenetics and biochemistry for medical and biomedical students.

Scientific Interests & Future Plans
My interest in human biology, and particularly the development of diseases driven by molecular dysregulated mechanisms in our cells, started already in school. During my undergraduate studies, this interest deepened further, especially in the field of cancer research. I want to broaden my knowledge of how genetic and epigenetic alterations contribute to cancer development, maintenance, and resistance to therapies. In addition, I am interested in the communication network with the surrounding cell types as well as the immune system, driven by the microenvironment. By enrolling in the DKFZ Master's program, I am grateful for the opportunity to learn from scientists from all over the world, to gain inside into current methods for investigating these questions, and to contribute to the development of new strategies to limit or even cure cancer in the future.

Contact: victoria.honekamp (at) dkfz.de
LinkedIn profile

Laura JOYA HARRISON (México)

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University Education
10/2024 - Present: M. Sc. in Molecular Biosciences - Major Cancer Biology, Ruprecht-Karls-University and German Cancer Research Center (DKFZ), Heidelberg, Germany.
08/2018 - 06/ 2023: B.Sc. in Biotechnology, Minor in Biocatalysis and Molecular Biology, Instituto Tecnológico y de Estudios Superiores de Monterrey, Monterrey, México.

Highest Degree: Bachelor of Science in Biotechnology
Title of the Bachelor's Thesis: Technologic and economic feasibility study of a bioengineering plant to produce ferulic acid from Nejayote for the prevention of skin damage in the form of a serum.

Internships/Work Experience
02/2024 - 04/2024 Laboratory Technician at "Grupo DIAGNOSTI-K" Medical and Diagnostic Laboratories, Puerto Vallarta, México. In charge of operation of hematology and immunology equipment and handling of patient samples for testing (clotting times, blood group, RH factor, erythrocyte sedimentation, febrile reactions, HIV, rapid plasma reagin).
03/2023 - 06/2023 Research Intern at "Centro del Agua para América Latina y el Caribe" ITESM, Monterrey, México, under direct supervision of Dr. Reyna Berenice González González and Dr. Hafiz Muhammad Nasir Iqbal. Literature review and writing about Biomass-derived carbon dots as sustainable nanomaterials for advanced biomedical applications.

Scientific Interests & Future Plans
If you want to live an interesting life you need to challenge yourself. When I decided to pursue a career that focuses on deciphering Cancer I knew it would be a heavy load but felt thrilled about engaging in it, and contributing to the scientific community that perseveres in the battle against this perplexing disease. During my time in DKFZ I plan to deepen my knowledge in the convergence of Stem Cell (SC) technology and Cancer, specifically how SC signaling mechanisms for maintenance and differentiation can be reflected in tumorigenesis, and how these models can be applied to design new therapeutic targets. Also would like to embark on the development of treatments that use SCs like a donor source for transplantation, as has been done to restore immune-surveillance and rescue the hematopoietic system in patients with Leukemia.

Contact: laurapaola.joyaharrison (at) dkfz.de
LinkedIn profile

Soham KARANDIKAR (India)

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University Education
10/2024 – present: M.Sc. in Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls-University Heidelberg and German Cancer Research Center (DKFZ), Germany
08/2020-04/2024: Bachelor of Science (Research)- Major Biology, Indian Institute of Science, Bangalore, India

Highest Degree: B.S.(Research) with Major Biology
Title of Bachelor's Thesis: Effect of particle endocytosis on the motility of macrophages

Internships/Work Experience
01/2024-04/2024: Bachelor's thesis at the Department of Bioengineering, Indian Institute of Science, India. Investigated the effect of the uptake of synthetic particles on the migratory capacities of cells of a murine macrophage cell line.
08/2023-12/2023: School of Biological Sciences, Nanyang Technological University, Singapore. Worked on characterizing the molecular mechanism underlying the anti-proliferative role of N-WASP in squamous cell carcinoma.
06/2023-07/2023: Department of Bioengineering, Indian Institute of Science, India. Worked on investigating phenotypic plasticity in helper T-cells using transcriptomic analysis techniques.
11/2022-04/2023: Department of Bioengineering, Indian Institute of Science, India. Worked on understanding the changes in functional capacities of innate immune cells upon interaction with non-stimulatory particles using RT-PCR
08/2022-10/2022: iGEM IISc, India. Member of the biology group of the undergraduate iGEM team of the Indian Institute of Science (IISc). Attempted to genetically engineer Pseudomonas putida to degrade halocarbons using different cloning strategies.
05/2022-07/2022: Department of Biochemistry, Indian Institute of Science, India. Worked on the biochemical characterization of a homolog of a yeast inositol pyrophosphatase from an early land plant species and performed its phylogenetic reconstruction with a focus on the plant kingdom.

Scientific Interests & Future Plans
I am fascinated by the molecular networks and signalling pathways involved in the maintenance of normal cellular physiology. I am further excited by the fact that these processes are affected by influences from the microenvironment of a cell and in turn influence its microenvironment. I find cancer an exciting model system to understand the molecular mechanisms governing physiological processes since these processes go awry in cancer. Since cancer cells interact with other cells of the human body and influence the physiology of these cells, I find it an exciting model system to understand what intercellular interactions are essential for homeostasis. Thus, I aspire to understand homeostatic processes in humans using cancer as a model system.

Contact: soham.karandikar (at) dkfz.de
LinkedIn profile

Sofia KASAPIDOU (Greece)

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University Education
Democritus University of Thrace, Greece (BSc 2020-2024)
University of Heidelberg, Germany (MSc 2024-2026)

Highest Degree: BSc in Molecular Biology & Genetics
Title of Bachelor's Thesis: Examining the Practical Applications of Environmental DNA (eDNA) Analysis in the Thracian Sea via Next-Generation Sequencing (NGS) Technology

Internships/Work Experience
none relevant to my field of studies

Scientific Interests & Future Plans
I am passionately interested in tumour immunology research, with a strong fascination for learning more about (viral) immunotherapy and gene therapy systems. The potential of this field to revolutionise cancer treatment and improve patient outcomes drives my commitment to learning and contributing. My goal is to deepen my laboratory work expertise, build a solid foundation in techniques essential for cutting-edge research, and strengthen my bioinformatics skills. By combining practical lab experience with computational knowledge, I wish to explore new avenues for cancer diagnostics and therapeutic interventions. Ultimately, I aspire to pursue doctoral research on enhancing medical diagnostics and therapies, contributing to new developments in personalised and precision medicine. I am eager to collaborate and engage in research that expands our understanding of the field, focusing on advancing oncology in ways that directly benefit patient care and treatment.

Contact: sofia.kasapidou (at) dkfz.de
LinkedIn profile

Lena KATZENSTEIN (Germany)

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UniversityEducation
10/2024 – present: M.Sc. Molecular Biosciences - Major Cancer Biology, Ruprecht-Karls-University Heidelberg and DKFZ, Germany
10/2020 – 08/2024: B.Sc. Molecular and Technical Medicine, Hochschule Furtwangen University, Germany

Highest Degree: B.Sc. in Molecular and Technical Medicine
Title of Thesis: Influence of calcitriol on the effect of photodynamic therapy in glioblastoma multiforme

Internships/Work Experience
07/2024 - 9/2024: Research internship in the laboratory of Prof. Morimoto at Northwestern University, supported by the DAAD "RISE weltweit program". Worked on developing a new C. elegans strain using CRISPR to identify protein-chaperone interactions in vivo in the context of proteostasis and aging, Chicago Area, USA
12/2023 – 05/2024: Bachelor's thesis work in the tumor immunology laboratory (LTI) of the LIFE Center of the LMU clinic, Munich, Germany
08/2022 – 12/2023: Intern and working student at Merck Sharp & Dohme GmbH (MSD) Germany in the global clinical trial operations (GCTO) department. Supported local study teams in conducting phase II and III clinical trials, Munich, Germany

Scientific Interests & Future Plans
My interest in cancer biology developed during my bachelor's program, where I was fascinated by its complexity, its importance in global health, and its interdisciplinary connections. I am particularly interested in personalized medicine, immunotherapy, and the role of genomics and proteomics in understanding cancer mechanisms. As a cancer biology student, I hope to expand my understanding of these areas as well as other relevant disciplines. I also look forward to gaining extensive training in research design and methodology, ultimately preparing me for a future career in science. Most importantly, I am very excited to join the DKFZ community and learn from leading experts in the field of cancer research.

Contact: lena.katzenstein (at) dkfz.de
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Kadri-Ann LAINDE (Estonia)

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University Education
10/2024 – present: M. Sc. In Molecular Biosciences – Major Cancer Biology, German Cancer Research Center (DKFZ) and Ruprecht-Karls University Heidelberg, Germany
10/2021 – 09/2024: B. Sc. in Molecular Medicine, University of Freiburg, Germany

Highest Degree: Bachelor of Science in Molecular Medicine
Title of Bachelor's Thesis: High-throughput characterization of activation potential for FGFR3 kinase domain point mutations

Internships/Work Experience
05/2024 – 08/2024: Bachelor's Thesis in the Research Group of Prof. Dr. Sven Diederichs at the Center for Translational Cell Research (ZTZ), Freiburg im Breisgau, Germany
03/2023 – 05/2023: Internship in the Research Group of Prof. Dr. Sven Diederichs at the Center for Translational Cell Research (ZTZ), Freiburg im Breisgau, Germany. Project: "Validation of targets from high throughput screen of nonstop extension mutations"

Publication
Ghosh, A., Riester, M., Pal, J., Lainde, K.-A., Tangermann, C., Wanninger, A., Dueren, U. K., Dhamija, S., & Diederichs, S. (2024). Suppressive cancer nonstop extension mutations increase C-terminal hydrophobicity and disrupt evolutionarily conserved amino acid patterns. Nature Communications, 15(1), 9209. https://doi.org/10.1038/s41467-024-52779-4

Scientific Interests & Future Plans
Cancer biology sparked my interest during my bachelor's studies, as I learned about the remarkable complexity and versatility that tumours exhibit. I am fascinated by the mechanisms through which the body's own cells can transform into something that is capable of bringing down the whole organism and more importantly, how to leverage this information to develop strategies for fighting tumours. Therefore, my interest is directed towards precision medicine and translational research, where I hope to work on innovative treatments and assist in bringing them closer to the clinic. It is with great enthusiasm that I join the DKFZ community, where I can work alongside students and researchers that share my passion and enthusiasm for cancer research and acquire the knowledge and skill set needed to contribute to this intriguing field.

Contact: kadri-ann.lainde (at) dkfz.de
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Marek PAVLICA (Czech Republic)

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University Education
10/2024 – present: M.Sc. in Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls University and German Cancer Research Centre (DKFZ), Heidelberg, Germany
10/2022 – 09/2024: B.Sc. in Chemical biology, KIT, Karlsruhe, Germany

Highest degree: B.Sc. in Chemical Biology
Title of Bachelor thesis: Functionalized high-load nanoparticles targeting CD44v6 as a selective drug delivery system to treat pancreatic cancer

Internships/Work Experience
02/2023 – 09/2024: Student worker in blood bank, Municipal Clinic Karlsruhe, Germany
01/2021 – 09/2022: Internship at Institute for Chemical Process Fundamentals CAS, Prague, Czech Republic
11/2018 – 02/2019: Internship at Chemical Institute of Charles University, Research group of Prof. Jan Kotek, Prague, Czech Republic

Publication
Mizerová, E., Kos, M., Jakubec, M., Pavlica, M., Církva, V., Žádný, J., Storch, J. and Beránek, T. (2024), Introduction of Phosphinine Ring into Aromatic Systems via Alkyne Cyclization. Adv. Synth. Catal., doi: 10.1002/adsc.202401203

Scientific Interests & Future Plans
Although my first scientific interest was in the field of chemistry, my subsequent studies of chemical biology and the final thesis on targeted treatment of cancer made me fall in love with the research on tumor biology. When I saw the enormous diversity of this field and understood why there is no universal "cure for cancer" even after decades of research, I became certain this is the area I want to dedicate myself to. As a student of this major, I hope to learn from the very best and then use this experience and knowledge to advance the battlefront in the fight against cancer. And get an M.Sc. and PhD in the meantime.

Contact: marek.pavlica (at) dkfz.de
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Lea REICHEL (Germany)

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University Education
10/2024 – present: M.Sc. Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls-University Heidelberg and German Cancer Research Center (DKFZ), Germany
10/2021 – 09/2024: B.Sc. Biomedical Science, Philipps University Marburg, Germany

Highest Degree: Bachelor of Science (B.Sc.) of Biomedical Science
Title of Bachelor's Thesis: Evaluation of the functional impact of adipocyte-derived secretome on ovarian cancer cells in vitro

Internships/Work Experience
02/2024 – 09/2024: Research internship and Bachelor thesis in Dr. Gómez-Serrano's laboratory at the Centre for Tumor Biology and Immunology (ZTI), Philipps University Marburg
04/2024 – 06/2024: Student Assistant at the Philipps University in Marburg; Supervision of biochemical and molecular biological laboratory practicals for biomedical science students
03/2023 – 06/2023: Student Assistant at the Philipps University in Marburg; Supervision of biochemical and molecular biological laboratory practicals for medical students
08/2022 – 09/2022: Research internship at the medical care centre for pathology and molecular diagnostics in Trier (MVZ Trier)

Scientific Interests & Future Plans
My interest in science was a prominent part of my childhood and led me to pursue a bachelor's degree in biomedical science with a focus on tumor biology. During this time I was able to gain first insights into the molecular and inter-cellular mechanisms involved in oncogenesis and metastasis, causing thousands of deaths each year. My thesis on ovarian carcinoma sparked my interest for gynaecological cancers, which I would like to pursue during my time at the DKFZ. I look forward to learning new topics and methods, as well as gaining knowledge on research design. I am happy to be a part of the DKFZ community and partake in cutting edge research alongside leading experts in the tumor biology field.

Contact: lea.reichel (at) dkfz.de
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Sofia Martina SALAMANCA TORRES (Bolivia)

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University Education
10/2024 - present: M.Sc. in Molecular Biosciences - Major Cancer Biology, German Cancer Research Center (DKFZ) and Ruprecht-Karls-Universität Heidelberg, Germany
10/2020 - 09/2024: B.Sc. in Molecular Medicine, Eberhard Karls Universität Tübingen, Germany

Highest Degree: B.Sc. Molecular Medicine
Title of Bachelor's Thesis: T Cell-based Screening for Identification of Immunogenic Peptides Derived from MYCN Protein as Basis for a Peptide Vaccine to Treat Neuroblastoma During Minimal Residual Disease

Internships/Work Experience
08/2023 - 10/2023: Research Internship at the Research Group of Dr. Madhuri Salker, Universitäts-Frauenklinik, Tübingen, Germany
02/2024 - 09/2024: Bachelor's Thesis at the Clinical Immunotherapy Research Group of Prof. Dr. med. Peter Lang, Klinik für Kinder- und Jugendmedizin, Tübingen, Germany

Scientific Interests & Future Plans
I am currently interested in translational research in immuno-oncology, particularly how therapeutic approaches such as CAR T-cell therapies, checkpoint inhibitors, and personalized peptide vaccines can enhance the immune system's capacity to target and eliminate cancer cells. I am eager to utilize my time at DKFZ to deepen my understanding of immuno-oncology, gain insights into the current advancements in the field, and engage in discussions about the next steps needed to drive future progress. Additionally, I have a strong interest in pediatric oncology. In the future I would like to be part of research teams focused on developing innovative therapies for children. As I embark on my Master's in Cancer Biology, I am also looking forward to broadening my knowledge of other critical areas in cancer research, such as the roles of cancer stem cells and the role of tumor microenvironment in cancer progression and treatment resistance.

Contact: sofiamartina.salamancatorres (at) dkfz.de
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Luna SCHÖRKEN (Germany)

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University Education
10/2024 - present: M.Sc. in Molecular Biosciences – Major Cancer Biology, German Cancer Research Center (DKFZ) and Ruprecht-Karls-University Heidelberg, Germany
10/2021 - 07/2024: B. Sc. in Biochemistry, Ruprecht-Karls-University Heidelberg, Germany

Highest Degree: Bachelor of Science in Biochemistry
Title of Bachelor's Thesis: Synthetic hepatitis E virus chimera

Internships/Work Experience
03/2024 – present: Student assistant (HiWi) in Prof. Dr. Michael Knop's laboratory, Center for Molecular Biology (ZMBH), Heidelberg, Germany
04/2024 – 06/2024: Bachelor's Thesis in Prof. Dr. Michael Knop's laboratory, Center for Molecular Biology (ZMBH) & Dr. Dao Thi's laboratory, Center of Integrative Infectious Disease Research (CIID), Heidelberg, Germany

Scientific Interests & Future Plans
The evolution of life from simple molecules to complex organisms is a process that spans billions of years. Over time, basic chemical reactions have evolved into increasingly complex systems where the smallest disruption can lead to diseases such as cancer. I find it fascinating how small molecular changes can affect health and would like to understand this better in the future. My Bachelor's degree in Biochemistry has strengthened my interest in cancer research and provided me with a solid foundation. As part of the Major Cancer Biology program at the DKFZ, I would like to gain deeper insights into different areas of research and aquire practical experience. My ultimate goal is to contribute to the development of innovative cancer therapies.

Contact: lunakristina.schoerken (at) dkfz.de
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Kieran SCHULENBERG (Germany)

Rebeka SHARKO (Albania)

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University Education
10/2024 – Present: M.Sc. Molecular Biosciences – Major Cancer Biology, Ruprecht-Karls-University Heidelberg and German Cancer Research Center (DKFZ), Germany.
09/2021 – 06/2024: B.Sc. in Biochemistry and Cell Biology, Jacobs University Bremen, Germany

Highest Degree: Bachelor of Science in Biochemistry and Cell Biology
Title of Bachelor's Thesis: An enzyme for NAD+-dependent methanol oxidation in Saccharomyces cerevisiae

Internships/Work Experience
10/2023 – 05/2024: Research Assistant in the laboratory of Prof. Dr. Elke Nevoigt, aiming to genetically engineer S. cerevisiae strains in order to produce succinic acid by channelling C1 substrates (methanol) into the central carbon metabolism.
09/2022 – 05/2024: Teaching Assistant at Jacobs University Bremen for the General and Inorganic Chemistry course (Fall Semester 2022, 2023), Introduction to Biotechnology: Microbiology and Genetics course and lab (Spring Semester 2023, 2024), Advanced Biotechnology lab (January 2024) and Immunology course (Spring Semester 2024).
08/2023 – 09/2023: Intern in the Department of Molecular Biology and Genetics at Aarhus University, Denmark. Part of the research group of Prof. Lotte Bjergbæk, focusing on utilizing the Flp-Nick system to study topoisomerase-mediated DNA damage and the function of various gene products on the DNA repair pathways of different S. cerevisiae strains.

Scientific Interests/Future Plans
In the future, I intend to focus on advancing the field of immunology, particularly in leveraging the body's natural defence mechanisms to combat diseases such as cancer. My goal is to contribute to the development of innovative immunotherapies that harness the immune system's ability to selectively target and eliminate cancer cells. Additionally, I am highly interested in personalized medicine, where treatments are tailored based on an individual's genetic and immunological profile. By integrating these approaches, I aim to contribute to the development of more precise and effective therapeutic strategies that improve patient outcomes and advance the field of precision oncology.

Contact: rebeka.sharko (at) dkfz.de
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Meghna Ravishankar VALAKATTE (India)

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University Education
Bachelor of Technology at PES University, Bengaluru, India (2019-2023). Major in Biotechnology, minor in Computer Science.

Highest degree: B. Tech in Biotechnology
Title of Thesis: Dynamics of the innate immune system under multiple inflammatory conditions

Internships/Work Experience
June 2022 – June 2024: Research assistant at the Indian Institute of Science (IISc), India. project 1: Dynamics of the innate immune system under multiple inflammatory conditions in mouse models. project 2: Effect of phagocytosis on migration and development in Dictyostelium
January 2022 – December 2022: Undergraduate Researcher at People's Education Society University (PESU), India. In-vitro and in-silico studies on anticancer activities of plant extracts.
September 2021 – November 2021: Industrial Research Trainee at International Stemcell Services Limited (iCREST), India. Animal cell culture and in-vitro drug cytotoxicity testing.
July 2021: Research Intern at the National Institute of Mental Health and Neurosciences (NIMHANS), India. Diagnosis of trinucleotide repeat neurodegenerative disorders.
August 2021 - March 2022: Biology tutor at Refining Skills Academy, India.

Publications
Valakatte, M. R., Viswanath, V., Aithal, M., Karunakar, P., & Narayanappa, S. K. (2024). In-vitro and in-silico evaluation of anticancer potential of Oxalis corniculata. Advances in Traditional Medicine, 1-11. https://doi.org/10.1007/s13596-024-00777-8
Valakatte, M. R., & Kavitha, R. V. (2022). Antibacterial mechanisms of plant essential oils and conditions influencing their variability. Acta Microbiologica Bulgaria, 38(3), 163-179.

Patent Application
Diagnostic arrangement for sanitary napkin to detect and analyze analytes in menstrual blood (October 2023) - Application Number: 18/401,744 (USA), 202341074277 (India)

Scientific Interests & Future Plans
I am interested in the regulation of cancer by neuronal and immune processes. My background in immunology has led me to wonder if the nervous and the immune systems coordinate their responses to disease, particularly cancer - which I consider to be a "rebellion" of cells against the multicellular system. During my time at DKFZ, I would like to collect various perspectives on how cancer works, and what would be the best way to treat it. I am passionate about strategizing and executing big-picture ideas, and I am excited to use my experience at DKFZ to make significant contributions to the global fight against cancer.

Contact: meghna.valakatte (at) dkfz.de
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Nathalie ZEHETNER (Germany)

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University Education
10.2024 – present: M.Sc. in Molecular Biosciences – Major Cancer Biology, German Cancer Research Center (DKFZ) and Ruprecht-Karls-University Heidelberg, Germany
10.2020 – 05.2024: B.Sc. Biology, RWTH Aachen University

Highest Degree: B.Sc. Biology
Title of Thesis: Establishing interaction analysis for new, potential binders as diagnostic reagents - mainly using biosensor-technologies or orthogonal methodologies

Internships/Work Experience
04-09.2023: Internship in the Biomolecular interaction analysis team at Roche Diagnostics (Penzberg, Bavaria), characterizing binding interactions between antibodies and targeted antigens using surface plasmon resonance (SPR) methods.


Scientific Interests & Future Plans
Having gained experience in both knowledge-focused research at university and patient-focused research in the pharmaceutical industry, I wish to combine these focuses by studying cancer biology at the DKFZ. Cancer is an indisputably relevant disease that is deeply intertwined with some of the most fundamental processes of multicellular life. Cancer research therefore unites two motivations that drive me in pursuing a career as a research scientist: understanding how life works in the most fundamental ways and using this knowledge to help people to live longer and better lives. As a student in the major Cancer Biology at the DKFZ I strive to explore the diverse field of cancer research and to find a focus to dive into, both during the research internships and in my master thesis.

Contact: nathalie.zehetner (at) dkfz.de
LinkedIn profile

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