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Research

Publications 2020

Coomans, M. B. ; Dirven, L. ; Aaronson, N. K. ; Baumert, B. G. ; van den Bent, M. ; Bottomley, A. ; Brandes, A. A. ; Chinot, O. ; Coens, C. ; Gorlia, T. ; Herrlinger, U. ; Keime-Guibert, F. ; Malmström, A. ; Martinelli, F. ; Sloan, J. A. ; Stupp, R. ; Talacchi, A. ; Weller, M. ; Wick, W. ; Reijneveld, J. C. ; Taphoorn, M. J. B.
Calculating the net clinical benefit in neuro-oncology clinical trials using two methods: quality-adjusted survival effect sizes and joint modeling.
Neuro-oncology advances 2(1), vdaa147 (2020) [10.1093/noajnl/vdaa147]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Caramanna, I. ; Bottomley, A. ; Drijver, A. J. ; Twisk, J. ; van den Bent, M. ; Idbaih, A. ; Wick, W. ; Pe, M. ; Klein, M. ; Reijneveld, J. C. ; Group, E. Q. o. L. G. a. B. T. (Collaboration Author)
Objective neurocognitive functioning and neurocognitive complaints in patients with high-grade glioma: Evidence of cognitive awareness from the European Organisation for Research and Treatment of Cancer brain tumour clinical trials.
European journal of cancer 144, 162 - 168 (2020) [10.1016/j.ejca.2020.10.040]2020 BibTeX | EndNote: XML, Text | RIS

Busetto, L. ; Wick, W. ; Gumbinger, C.
How to use and assess qualitative research methods.
Neurological research and practice 2(1), 14 (2020) [10.1186/s42466-020-00059-z]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Coomans, M. B. ; Taphoorn, M. J. B. ; Aaronson, N. K. ; Baumert, B. G. ; van den Bent, M. ; Bottomley, A. ; Brandes, A. A. ; Chinot, O. ; Coens, C. ; Gorlia, T. ; Herrlinger, U. ; Keime-Guibert, F. ; Malmström, A. ; Martinelli, F. ; Stupp, R. ; Talacchi, A. ; Weller, M. ; Wick, W. ; Reijneveld, J. C. ; Dirven, L.
Measuring change in health-related quality of life: the impact of different analytical methods on the interpretation of treatment effects in glioma patients
Neuro-oncology practice 7(6), 668 - 675 (2020) [10.1093/nop/npaa033]2020 BibTeX | EndNote: XML, Text | RIS

Boxerman, J. L. (Corresponding author) ; Quarles, C. C. ; Hu, L. S. ; Erickson, B. J. ; Gerstner, E. R. ; Smits, M. ; Kaufmann, T. J. ; Barboriak, D. P. ; Huang, R. H. ; Wick, W. ; Weller, M. ; Galanis, E. ; Kalpathy-Cramer, J. ; Shankar, L. ; Jacobs, P. ; Chung, C. ; van den Bent, M. J. ; Chang, S. ; Al Yung, W. K. ; Cloughesy, T. F. ; Wen, P. Y. ; Gilbert, M. R. ; Rosen, B. R. ; Ellingson, B. M. ; Schmainda, K. M. ; Arons, D. F. ; Kingston, A. ; Sandak, D. ; Wallace, M. ; Musella, A. ; Haynes, C.
Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas
Neuro-Oncology 22(9), 1262 - 1275 (2020) [10.1093/neuonc/noaa141]2020 BibTeX | EndNote: XML, Text | RIS

Pace, A. ; Koekkoek, J. A. F. ; van den Bent, M. J. ; Bulbeck, H. J. ; Fleming, J. ; Grant, R. ; Golla, H. ; Henriksson, R. ; Kerrigan, S. ; Marosi, C. ; Oberg, I. ; Oberndorfer, S. ; Oliver, K. ; Pasman, H. R. W. ; Le Rhun, E. ; Rooney, A. G. ; Rudà, R. ; Veronese, S. ; Walbert, T. ; Weller, M. ; Wick, W. ; Taphoorn, M. J. B. ; Dirven, L.
Determining medical decision-making capacity in brain tumor patients: why and how?
Neuro-oncology practice 7(6), 599 - 612 (2020) [10.1093/nop/npaa040]2020 BibTeX | EndNote: XML, Text | RIS

Johnson, R. M. ; Phillips, H. S. ; Bais, C. ; Brennan, C. W. ; Cloughesy, T. F. ; Daemen, A. ; Herrlinger, U. ; Jenkins, R. B. ; Lai, A. ; Mancao, C. ; Weller, M. ; Wick, W. ; Bourgon, R. (Corresponding author) ; Garcia, J.
Development of a gene expression?based prognostic signature for IDH wild-type glioblastoma
Neuro-Oncology 22(12), 1742-1756 (2020) [10.1093/neuonc/noaa157]2020 BibTeX | EndNote: XML, Text | RIS

Seystahl, K. ; Hentschel, B. ; Loew, S. ; Gramatzki, D. ; Felsberg, J. ; Herrlinger, U. ; Westphal, M. ; Schackert, G. ; Thon, N. ; Tatagiba, M. ; Pietsch, T. ; Reifenberger, G. ; Löffler, M. ; Wick, W. ; Weller, M.
Bevacizumab versus alkylating chemotherapy in recurrent glioblastoma
Journal of cancer research and clinical oncology 146(3), 659-670 (2019) [10.1007/s00432-019-03086-9]2019 BibTeX | EndNote: XML, Text | RIS

Wen, P. Y. ; Weller, M. ; Lee, E. Q. ; Alexander, B. M. ; Barnholtz-Sloan, J. S. ; Barthel, F. P. ; Batchelor, T. T. ; Bindra, R. S. ; Chang, S. M. ; Chiocca, E. A. ; Cloughesy, T. F. ; DeGroot, J. F. ; Galanis, E. ; Gilbert, M. R. ; Hegi, M. E. ; Horbinski, C. ; Huang, R. Y. ; Lassman, A. B. ; Le Rhun, E. ; Lim, M. ; Mehta, M. P. ; Mellinghoff, I. K. ; Minniti, G. ; Nathanson, D. ; Platten, M. ; Preusser, M. ; Roth, P. ; Sanson, M. ; Schiff, D. ; Short, S. C. ; Taphoorn, M. J. B. ; Tonn, J.-C. ; Tsang, J. ; Verhaak, R. G. W. ; von Deimling, A. ; Wick, W. ; Zadeh, G. ; Reardon, D. A. ; Aldape, K. D. ; van den Bent, M. J.
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions.
Neuro-Oncology 22(8), 1073 - 1113 (2020) [10.1093/neuonc/noaa106]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Valiente, M. ; Van Swearingen, A. E. D. ; Anders, C. K. ; Bairoch, A. ; Boire, A. ; Bos, P. D. ; Cittelly, D. M. ; Erez, N. ; Ferraro, G. B. ; Fukumura, D. ; Gril, B. ; Herlyn, M. ; Holmen, S. L. ; Jain, R. K. ; Joyce, J. A. ; Lorger, M. ; Massague, J. ; Neman, J. ; Sibson, N. R. ; Steeg, P. S. ; Thorsen, F. ; Young, L. S. ; Vare?lija, D. ; Vultur, A. ; Weis-Garcia, F. ; Winkler, F. (Last author)
Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines
Cancer research 80(20), 4314 - 4323 (2020) [10.1158/0008-5472.CAN-20-0291]2020 BibTeX | EndNote: XML, Text | RIS

Kessler, T. (First author) ; Berberich, A. ; Sadik, A. ; Sahm, F. ; Gorlia, T. ; Meisner, C. ; Hoffmann, D. C. F. ; Wick, A. ; Kickingereder, P. ; Rübmann, P. ; Bendszus, M. ; Opitz, C. ; Weller, M. ; Bent, M. ; Stupp, R. ; Winkler, F. ; Brandes, A. ; Deimling, A. ; Platten, M. ; Wick, W. (Last author)
Methylome analyses of three glioblastoma cohorts reveal chemotherapy sensitivity markers within DDR genes
Cancer medicine 9(22), 8373-8385 (2020) [10.1002/cam4.3447]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Goldbrunner, R. ; Weller, M. ; Regis, J. ; Lund-Johansen, M. ; Stavrinou, P. ; Reuss, D. ; Evans, D. G. ; Lefranc, F. ; Sallabanda, K. ; Falini, A. ; Axon, P. ; Sterkers, O. ; Fariselli, L. ; Wick, W. ; Tonn, J.-C.
EANO guideline on the diagnosis and treatment of vestibular schwannoma.
Neuro-Oncology 22(1), 31 - 45 (2020) [10.1093/neuonc/noz153]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Kovalchuk, B. (First author) ; Berghoff, A. S. ; Karreman, M. A. ; Frey, K. ; Piechutta, M. ; Fischer, M. ; Grosch, J. ; Heiland, S. ; Breckwoldt, M. O. ; Hilberg, F. ; Wick, W. ; Winkler, F. (Last author)
Nintedanib and a bi-specific anti-VEGF/Ang2 nanobody selectively prevent brain metastases of lung adenocarcinoma cells.
Clinical & experimental metastasis 37(6), 637-648 (2020) [10.1007/s10585-020-10055-x]2020 BibTeX | EndNote: XML, Text | RIS

Narayanan, A. ; Blanco-Carmona, E. ; Demirdizen, E. ; Sun, X. ; Herold-Mende, C. ; Schlesner, M. ; Turcan, S.
Nuclei Isolation from Fresh Frozen Brain Tumors for Single-Nucleus RNA-seq and ATAC-seq
JoVE journal 2020(162), e61542 (2020) [10.3791/61542]2020 BibTeX | EndNote: XML, Text | RIS

Kudo, T. (First author) ; Prentzell, M. T. ; Mohapatra, S. R. ; Sahm, F. ; Zhao, Z. ; Grummt, I. ; Wick, W. ; Opitz, C. A. ; Platten, M. ; Green, E. (Last author)
Constitutive Expression of the Immunosuppressive Tryptophan Dioxygenase TDO2 in Glioblastoma Is Driven by the Transcription Factor C/EBP?
Frontiers in immunology 11, 657 (2020) [10.3389/fimmu.2020.00657]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Banan, R. ; Stichel, D. ; Bleck, A. ; Hong, B. ; Lehmann, U. ; Suwala, A. ; Reinhardt, A. ; Schrimpf, D. ; Buslei, R. ; Stadelmann, C. ; Ehlert, K. ; Prinz, M. ; Acker, T. ; Schittenhelm, J. ; Kaul, D. ; Schweizer, L. ; Capper, D. ; Harter, P. ; Etminan, N. ; Jones, D. T. W. ; Pfister, S. M. ; Herold-Mende, C. ; Wick, W. ; Sahm, F. ; von Deimling, A. ; Hartmann, C. ; Reuß, D. (Last author)
Infratentorial IDH-mutant astrocytoma is a distinct subtype.
Acta neuropathologica 140(4), 569-581 (2020) [10.1007/s00401-020-02194-y]2020 BibTeX | EndNote: XML, Text | RIS

Michalak, M. ; Katzenmaier, E.-M. ; Roeckel, N. ; Woerner, S. M. ; Fuchs, V. ; Warnken, U. ; Yuan, Y. P. ; Bork, P. ; Neu-Yilik, G. ; Kulozik, A. ; von Knebel Doeberitz, M. ; Kloor, M. ; Kopitz, J. ; Gebert, J. (Last author)
(Phospho)proteomic Profiling of Microsatellite Unstable CRC Cells Reveals Alterations in Nuclear Signaling and Cholesterol Metabolism Caused by Frameshift Mutation of NMD Regulator UPF3A.
International journal of molecular sciences 21(15), E5234 (2020) [10.3390/ijms21155234]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Kickingereder, P. ; Brugnara, G. ; Hansen, M. B. ; Nowosielski, M. ; Pflüger, I. ; Schell, M. ; Isensee, F. ; Foltyn, M. ; Neuberger, U. ; Kessler, T. ; Sahm, F. ; Wick, A. ; Heiland, S. ; Weller, M. ; Platten, M. ; von Deimling, A. ; Maier-Hein, K. ; Østergaard, L. ; van den Bent, M. J. ; Gorlia, T. ; Wick, W. ; Bendszus, M.
Noninvasive Characterization of Tumor Angiogenesis and Oxygenation in Bevacizumab-treated Recurrent Glioblastoma by Using Dynamic Susceptibility MRI: Secondary Analysis of the European Organization for Research and Treatment of Cancer 26101 Trial.
Radiology 297(1), 164-175 (2020) [10.1148/radiol.2020200978]2020 BibTeX | EndNote: XML, Text | RIS

Vogelbaum, M. A. ; Krivosheya, D. ; Borghei-Razavi, H. ; Sanai, N. ; Weller, M. ; Wick, W. ; Soffietti, R. ; Reardon, D. A. ; Aghi, M. K. ; Galanis, E. ; Wen, P. Y. ; van den Bent, M. ; Chang, S.
Phase 0 and Window of Opportunity Clinical Trial Design in Neuro-Oncology: A RANO Review.
Neuro-Oncology 22(11), 1568-1579 (2020) [10.1093/neuonc/noaa149]2020 BibTeX | EndNote: XML, Text | RIS

Lassman, A. B. ; Joanta-Gomez, A. E. ; Pan, P. C. ; Wick, W. (Last author)
Current usage of tumor treating fields for glioblastoma.
Neuro-oncology advances 2(1), vdaa069 (2020) [10.1093/noajnl/vdaa069]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Fairless, R. (First author) ; Williams, S. K. ; Katiyar, R. ; Maxeiner, S. ; Schmitz, F. ; Diem, R. (Last author)
ERG Responses in Mice with Deletion of the Synaptic Ribbon Component RIBEYE.
Investigative ophthalmology & visual science 61(5), 37 (2020) [10.1167/iovs.61.5.37]2020 BibTeX | EndNote: XML, Text | RIS

Foltyn, M. ; Nieto Taborda, K. N. ; Neuberger, U. ; Brugnara, G. ; Reinhardt, A. ; Stichel, D. ; Heiland, S. ; Herold-Mende, C. ; Unterberg, A. ; Debus, J. ; von Deimling, A. ; Wick, W. ; Bendszus, M. ; Kickingereder, P.
T2/FLAIR-mismatch sign for noninvasive detection of IDH-mutant 1p/19q non-codeleted gliomas: validity and pathophysiology.
Neuro-oncology advances 2(1), vdaa004 (2020) [10.1093/noajnl/vdaa004]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Berghoff, A. S. (First author) ; Breckwoldt, M. O. ; Riedemann, L. ; Karimian-Jazi, K. ; Loew, S. ; Schlieter, F. ; Furtner, J. ; Cinci, M. ; Thomas, M. ; Strowitzki, M. J. ; Marmé, F. ; Michel, L. L. ; Schmidt, T. ; Jäger, D. ; Bendszus, M. ; Preusser, M. ; Wick, W. ; Winkler, F. (Last author)
Bevacizumab-based treatment as salvage therapy in patients with recurrent symptomatic brain metastases.
Neuro-oncology advances 2(1), vdaa038 (2020) [10.1093/noajnl/vdaa038]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Kessler, T. (First author) ; Berberich, A. ; Casalini, B. ; Drüschler, K. ; Ostermann, H. ; Dormann, A. ; Walter, S. ; Hai, L. ; Schlesner, M. ; Herold-Mende, C. ; Jungk, C. ; Unterberg, A. ; Bendszus, M. ; Sahm, K. ; von Deimling, A. ; Winkler, F. ; Platten, M. ; Wick, W. ; Sahm, F. ; Wick, A. (Last author)
Molecular profiling-based decision for targeted therapies in IDH wild-type glioblastoma.
Neuro-oncology advances 2(1), vdz060 (2020) [10.1093/noajnl/vdz060]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Hielscher, T. ; Schrimpf, D. ; Stichel, D. ; Reuss, D. E. ; Berghoff, A. S. ; Neidert, M. C. ; Wirsching, H.-G. ; Mawrin, C. ; Ketter, R. ; Paulus, W. ; Reifenberger, G. ; Lamszus, K. ; Westphal, M. ; Etminan, N. ; Ratliff, M. ; Herold-Mende, C. ; Pfister, S. M. ; Jones, D. T. W. ; Weller, M. ; Harter, P. N. ; Wick, W. ; Preusser, M. ; von Deimling, A. ; Sahm, F. (Last author)
CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas.
Acta neuropathologica 140(3), 409-413 (2020) [10.1007/s00401-020-02188-w]2020 BibTeX | EndNote: XML, Text | RIS

Jung, E. (First author) ; Alfonso, J. ; Monyer, H. ; Wick, W. ; Winkler, F. (Last author)
Neuronal signatures in cancer.
International journal of cancer 147(12), 3281-3291 (2020) [10.1002/ijc.33138]2020 BibTeX | EndNote: XML, Text | RIS

Climans, S. A. ; Brandes, A. A. ; Cairncross, J. G. ; Ding, K. ; Fay, M. ; Laperriere, N. ; Menten, J. ; Nishikawa, R. ; O'Callaghan, C. J. ; Perry, J. R. ; Phillips, C. ; Roa, W. ; Wick, W. ; Winch, C. ; Mason, W. P.
Temozolomide and seizure outcomes in a randomized clinical trial of elderly glioblastoma patients.
Journal of neuro-oncology 149(1), 65-71 (2020) [10.1007/s11060-020-03573-x]2020 BibTeX | EndNote: XML, Text | RIS

Berberich, A. ; Bartels, F. ; Tang, Z. ; Knoll, M. ; Pusch, S. ; Hucke, N. ; Kessler, T. ; Dong, Z. ; Wiestler, B. ; Winkler, F. ; Platten, M. ; Wick, W. ; Abdollahi, A. ; Lemke, D.
LAPTM5-CD40 Crosstalk in Glioblastoma Invasion and Temozolomide Resistance.
Frontiers in oncology 10, 747 (2020) [10.3389/fonc.2020.00747]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Kiesel, B. ; Thome, C. ; Weiss, T. ; Jakola, A. S. ; Darlix, A. ; Pellerino, A. ; Furtner, J. ; Kerschbaumer, J. ; Freyschlag, C. F. ; Wick, W. ; Preusser, M. ; Widhalm, G. ; Berghoff, A. S.
Perioperative imaging in patients treated with resection of brain metastases: a survey by the European Association of Neuro-Oncology (EANO) Youngsters committee.
BMC cancer 20(1), 410 (2020) [10.1186/s12885-020-06897-z]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Schell, M. ; Pflüger, I. ; Brugnara, G. ; Isensee, F. ; Neuberger, U. ; Foltyn, M. ; Kessler, T. ; Sahm, F. ; Wick, A. ; Nowosielski, M. ; Heiland, S. ; Weller, M. ; Platten, M. ; Maier-Hein, K. H. ; von Deimling, A. ; van den Bent, M. J. ; Gorlia, T. ; Wick, W. ; Bendszus, M. ; Kickingereder, P.
Validation of diffusion MRI phenotypes for predicting response to bevacizumab in recurrent glioblastoma: post-hoc analysis of the EORTC-26101 trial.
Neuro-Oncology 22(11), 1667-1676 (2020) [10.1093/neuonc/noaa120]2020 BibTeX | EndNote: XML, Text | RIS

Dirven, L. ; Luerding, R. ; Beier, D. ; Bumes, E. ; Reinert, C. ; Seidel, C. ; Bonsanto, M. M. ; Bremer, M. ; Rieken, S. ; Combs, S. E. ; Herrlinger, U. ; Seliger, C. ; Kuntze, H. ; Mayer-Steinacker, R. ; Dieing, A. ; Bartels, C. ; Schnell, O. ; Weyerbrock, A. ; Seidel, S. ; Grauer, O. ; Nadji-Ohl, M. ; Paulsen, F. ; Weller, M. ; Wick, W. ; Hau, P.
Neurocognitive functioning and health-related quality of life in adult medulloblastoma patients: long-term outcomes of the NOA-07 study.
Journal of neuro-oncology 148(1), 117-130 (2020) [10.1007/s11060-020-03502-y]2020 BibTeX | EndNote: XML, Text | RIS

Bernhardt, D. ; Wick, W. ; Weiss, S. E. ; Sahgal, A. ; Lo, S. S. ; Suh, J. H. ; Chang, E. L. ; Foote, M. ; Perry, J. ; Meyer, B. ; Vajkoczy, P. ; Wen, P. Y. ; Straube, C. ; Pigorsch, S. ; Wilkens, J. J. ; Combs, S. E.
Neuro-oncology Management During the COVID-19 Pandemic With a Focus on WHO Grade III and IV Gliomas.
Neuro-Oncology 22(7), 928-935 (2020) [10.1093/neuonc/noaa113]2020 BibTeX | EndNote: XML, Text | RIS

Monje, M. ; Borniger, J. C. ; D'Silva, N. J. ; Deneen, B. ; Dirks, P. B. ; Fattahi, F. ; Frenette, P. S. ; Garzia, L. ; Gutmann, D. H. ; Hanahan, D. ; Hervey-Jumper, S. L. ; Hondermarck, H. ; Hurov, J. B. ; Kepecs, A. ; Knox, S. M. ; Lloyd, A. C. ; Magnon, C. ; Saloman, J. L. ; Segal, R. A. ; Sloan, E. K. ; Sun, X. ; Taylor, M. D. ; Tracey, K. J. ; Trotman, L. C. ; Tuveson, D. A. ; Wang, T. C. ; White, R. A. ; Winkler, F.
Roadmap for the Emerging Field of Cancer Neuroscience.
Cell 181(2), 219 - 222 (2020) [10.1016/j.cell.2020.03.034]2020 BibTeX | EndNote: XML, Text | RIS

Karreman, M. (First author) ; Winkler, F. (Last author)
Targeting an adhesion molecule to prevent brain colonization of lung cancer.
Neuro-Oncology 22(7), 899-900 (2020) [10.1093/neuonc/noaa099]2020 BibTeX | EndNote: XML, Text | RIS

Wick, W. (First author) ; Wagener, R. J. (Last author)
Not Yet Another Negative Trial-ReACTing on Recent Glioblastoma Trials.
Clinical cancer research 26(7), 1535 - 1537 (2020) [10.1158/1078-0432.CCR-19-4032]2020 BibTeX | EndNote: XML, Text | RIS

Paech, D. (First author) ; Nagel, A. ; Schultheiss, M. N. ; Umathum, R. ; Regnery, S. ; Scherer, M. ; Wick, A. ; Platt, T. ; Wick, W. ; Bendszus, M. ; Unterberg, A. ; Schlemmer, H.-P. ; Ladd, M. ; Niesporek, S. (Last author)
Quantitative Dynamic Oxygen 17 MRI at 7.0 T for the Cerebral Oxygen Metabolism in Glioma
Radiology 295(1), 181 - 189 (2020) [10.1148/radiol.2020191711]2020 BibTeX | EndNote: XML, Text | RIS

Wick, A. (First author) ; Desjardins, A. ; Suarez, C. ; Forsyth, P. ; Gueorguieva, I. ; Burkholder, T. ; Cleverly, A. L. ; Estrem, S. T. ; Wang, S. ; Lahn, M. M. ; Guba, S. C. ; Capper, D. ; Rodon, J.
Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma.
Investigational new drugs 38(5), 1570-1579 (2020) [10.1007/s10637-020-00910-9]2020 BibTeX | EndNote: XML, Text | RIS

Aslan, K. (First author) ; Turco, V. ; Blobner, J. ; Sonner, J. ; Liuzzi, A. R. ; Núñez, N. G. ; De Feo, D. ; Kickingereder, P. ; Fischer, M. ; Green, E. ; Sadik, A. ; Friedrich, M. ; Sanghvi, K. ; Kilian, M. ; Cichon, F. ; Wolf, L. ; Jähne, K. ; von Landenberg, A. ; Bunse, L. ; Sahm, F. ; Schrimpf, D. ; Meyer, J. ; Alexander, A. ; Brugnara, G. ; Röth, R. ; Pfleiderer, K. ; Niesler, B. ; von Deimling, A. ; Opitz, C. ; Breckwoldt, M. ; Heiland, S. ; Bendszus, M. ; Wick, W. ; Becher, B. ; Platten, M. (Last author)
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas.
Nature Communications 11(1), 931 (2020) [10.1038/s41467-020-14642-0]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Schlüter, A. ; Aksan, B. ; Diem, R. ; Fairless, R. ; Mauceri, D.
VEGFD Protects Retinal Ganglion Cells and, consequently, Capillaries against Excitotoxic Injury.
Molecular therapy Methods & clinical development [...] 17, 281 - 299 (2020) [10.1016/j.omtm.2019.12.009]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Karimian-Jazi, K. (First author) ; Münch, P. ; Alexander, A. ; Fischer, M. ; Pfleiderer, K. ; Piechutta, M. ; Karreman, M. A. ; Solecki, G. M. ; Berghoff, A. S. ; Friedrich, M. ; Deumelandt, K. ; Kurz, F. T. ; Wick, W. ; Heiland, S. ; Bendszus, M. ; Winkler, F. ; Platten, M. ; Breckwoldt, M. (Last author)
Monitoring innate immune cell dynamics in the glioma microenvironment by magnetic resonance imaging and multiphoton microscopy (MR-MPM).
Theranostics 10(4), 1873 - 1883 (2020) [10.7150/thno.38659]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Bojcevski, J. (First author) ; Stojic, A. ; Hoffmann, D. B. ; Williams, S. K. ; Müller, A. ; Diem, R. ; Fairless, R. (Last author)
Influence of retinal NMDA receptor activity during autoimmune optic neuritis.
Journal of neurochemistry 153(6), 693-709 (2020) [10.1111/jnc.14980]2020 BibTeX | EndNote: XML, Text | RIS

Kessler, T. (First author) ; Latzer, P. ; Schmid, D. ; Warnken, U. ; Saffari, A. ; Ziegler, A. ; Kollmer, J. ; Möhlenbruch, M. ; Ulfert, C. ; Herweh, C. ; Wildemann, B. ; Wick, W. ; Weiler, M.
Cerebrospinal fluid proteomic profiling in nusinersen-treated patients with spinal muscular atrophy.
Journal of neurochemistry 153(5), 650-661 (2020) [10.1111/jnc.14953]2020 BibTeX | EndNote: XML, Text | RIS

Brugnara, G. ; Isensee, F. ; Neuberger, U. ; Bonekamp, D. ; Petersen, J. ; Diem, R. ; Wildemann, B. ; Heiland, S. ; Wick, W. ; Bendszus, M. ; Maier-Hein, K. ; Kickingereder, P.
Automated volumetric assessment with artificial neural networks might enable a more accurate assessment of disease burden in patients with multiple sclerosis.
European radiology 30(4), 2356-2364 (2020) [10.1007/s00330-019-06593-y]2020 BibTeX | EndNote: XML, Text | RIS

Deng, M. Y. (First author) ; Sill, M. ; Sturm, D. ; Stichel, D. ; Witt, H. ; Ecker, J. ; Wittmann, A. ; Schittenhelm, J. ; Ebinger, M. ; Schuhmann, M. U. ; Figarella-Branger, D. ; Aronica, E. ; Staszewski, O. ; Preusser, M. ; Haberler, C. ; Lauten, M. ; Schüller, U. ; Hartmann, C. ; Snuderl, M. ; Dunham, C. ; Jabado, N. ; Wesseling, P. ; Deckert, M. ; Keyvani, K. ; Gottardo, N. ; Giangaspero, F. ; von Hoff, K. ; Ellison, D. W. ; Pietsch, T. ; Herold Mende, C. ; Milde, T. ; Witt, O. ; Kool, M. ; Korshunov, A. ; Wick, W. ; von Deimling, A. ; Pfister, S. M. ; Jones, D. T. W. ; Sahm, F. (Last author)
Diffuse Glioneuronal tumour with Oligodendroglioma-like features and Nuclear Clusters (DGONC) - a molecularly-defined glioneuronal CNS tumour class displaying recurrent monosomy 14.
Neuropathology & applied neurobiology 46(5), 422-430 (2020) [10.1111/nan.12590]2020 BibTeX | EndNote: XML, Text | RIS

van den Bent, M. ; Azaro, A. ; De Vos, F. ; Sepulveda, J. ; Yung, W. K. A. ; Wen, P. Y. ; Lassman, A. B. ; Joerger, M. ; Tabatabai, G. ; Rodon, J. ; Tiedt, R. ; Zhao, S. ; Kirsilae, T. ; Cheng, Y. ; Vicente, S. ; Balbin, O. A. ; Zhang, H. ; Wick, W. (Last author)
A Phase Ib/II, open-label, multicenter study of INC280 (capmatinib) alone and in combination with buparlisib (BKM120) in adult patients with recurrent glioblastoma.
Journal of neuro-oncology 146(1), 79-89 (2020) [10.1007/s11060-019-03337-2]2020 BibTeX | EndNote: XML, Text | RIS

Berberich, A. (First author) ; Schmitt, L.-M. ; Pusch, S. ; Hielscher, T. ; Rübmann, P. ; Hucke, N. ; Latzer, P. ; Heßling, B. ; Lemke, D. ; Kessler, T. ; Platten, M. ; Wick, W. (Last author)
cMyc and ERK activity are associated with resistance to ALK inhibitory treatment in glioblastoma.
Journal of neuro-oncology 146(1), 9-23 (2020) [10.1007/s11060-019-03348-z]2020 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Chiang, J. ; Schrimpf, D. ; Stichel, D. ; Paramasivam, N. ; Sill, M. ; Gayden, T. ; Casalini, B. ; Reuss, D. E. ; Dalton, J. ; Pajtler, K. W. ; Hänggi, D. ; Herold-Mende, C. ; Rushing, E. ; Korshunov, A. ; Mawrin, C. ; Weller, M. ; Schlesner, M. ; Wick, W. ; Jabado, N. ; Jones, D. T. W. ; Pfister, S. M. ; von Deimling, A. ; Ellison, D. W. ; Sahm, F. (Last author)
YAP1-fusions in pediatric NF2-wildtype meningioma.
Acta neuropathologica 139(1), 215-218 (2020) [10.1007/s00401-019-02095-9]2020 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Schrimpf, D. ; Stichel, D. ; Reuss, D. E. ; Hasselblatt, M. ; Hagel, C. ; Staszewski, O. ; Hench, J. ; Frank, S. ; Brandner, S. ; Korshunov, A. ; Wick, W. ; Pfister, S. M. ; Reifenberger, G. ; von Deimling, A. ; Sahm, F. (Last author) ; Jones, D. (Last author)
Posterior fossa pilocytic astrocytomas with oligodendroglial features show frequent FGFR1 activation via fusion or mutation.
Acta neuropathologica 139(2), 403-406 (2020) [10.1007/s00401-019-02097-7]2020 BibTeX | EndNote: XML, Text | RIS

Brand, F. ; Förster, A. ; Christians, A. ; Bucher, M. ; Thomé, C. M. ; Raab, M. S. ; Westphal, M. ; Pietsch, T. ; von Deimling, A. ; Reifenberger, G. ; Claus, P. ; Hentschel, B. ; Weller, M. ; Weber, R. G.
FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas.
Acta neuropathologica 139(1), 175-192 (2020) [10.1007/s00401-019-02067-z]2020 BibTeX | EndNote: XML, Text | RIS

Wick, A. ; Kessler, T. ; Platten, M. ; Meisner, C. ; Bamberg, M. ; Herrlinger, U. ; Felsberg, J. ; Weyerbrock, A. ; Papsdorf, K. ; Steinbach, J. P. ; Sabel, M. ; Vesper, J. ; Debus, J. ; Meixensberger, J. ; Ketter, R. ; Hertler, C. ; Mayer-Steinacker, R. ; Weisang, S. ; Bölting, H. ; Reuss, D. ; Reifenberger, G. ; Sahm, F. ; von Deimling, A. ; Weller, M. ; Wick, W. (Last author)
Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, MGMT promoter methylated malignant astrocytoma.
Neuro-Oncology 22(8), 1162 - 1172 (2020) [10.1093/neuonc/noaa033]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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