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Robador, J. R. ; Feinauer, M. (First author) ; Schneider, S. W. ; Mayer, F. T. ; Gorzelanny, C. ; Sacharow, A. ; Liu, X. ; Berghoff, A. S. ; Brehm, M. A. ; Hirsch, D. ; Stadler, J. ; Vidal-Y-Si, S. ; Wladykowski, E. ; Asong, M. ; Nowak, K. ; Seiz-Rosenhagen, M. ; Umansky, V. ; Mess, C. ; Pantel, K. ; Winkler, F. (Last author) ; Bauer, A. T. Involvement of platelet-derived VWF in metastatic growth of melanoma in the brain.
Neuro-oncology advances 3 (1 ), vdab175 (2021 ) [10.1093/noajnl/vdab175 ] 2021
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Kilian, M. (First author) ; Bunse, T. ; Wick, W. ; Platten, M. ; Bunse, L. (Last author) Genetically Modified Cellular Therapies for Malignant Gliomas
International journal of molecular sciences 22 (23 ), 12810 (2021 ) [10.3390/ijms222312810 ] 2021
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Karimian-Jazi, K. (First author) ; Neuberger, U. ; Schregel, K. ; Brugnara, G. ; Bendszus, M. ; Breckwoldt, M. ; Schwarz, D. ; Jäger, L. B. ; Wick, W. (Last author) Diagnostic value of gadolinium contrast administration for spinal cord magnetic resonance imaging in multiple sclerosis patients and correlative markers of lesion enhancement.
Multiple sclerosis journal - experimental, translational and clinical 7 (4 ), 205521732110479 - (2021 ) [10.1177/20552173211047978 ] 2021
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Jordan, B. ; Benesova, K. ; Hassel, J. C. ; Wick, W. ; Jordan, K. How we identify and treat neuromuscular toxicity induced by immune checkpoint inhibitors.
ESMO open 6 (6 ), 100317 (2021 ) [10.1016/j.esmoop.2021.100317 ] 2021
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Srinivasan, E. S. ; Deshpande, K. ; Neman, J. ; Winkler, F. (Last author) ; Khasraw, M. The microenvironment of brain metastases from solid tumors.
Neuro-oncology advances 3 (Supplement_5 ), v121-v132 (2021 ) [10.1093/noajnl/vdab121 ] 2021
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Lagrèze, W. A. ; Küchlin, S. ; Ihorst, G. ; et al Safety and efficacy of erythropoietin for the treatment of patients with optic neuritis (TONE): a randomised, double-blind, multicentre, placebo-controlled study.
The lancet <London> / Neurology 20 (12 ), 991 - 1000 (2021 ) [10.1016/S1474-4422(21)00322-7 ] 2021
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Fairless, R. (First author) ; Bading, H. ; Diem, R. Pathophysiological Ionotropic Glutamate Signalling in Neuroinflammatory Disease as a Therapeutic Target
Frontiers in neuroscience 15 , 741280 (2021 ) [10.3389/fnins.2021.741280 ] 2021
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Song, A. J. ; Ding, K. ; Alnahhas, I. ; Laperriere, N. J. ; Perry, J. ; Mason, W. P. ; Winch, C. ; O'Callaghan, C. J. ; Menten, J. J. ; Brandes, A. A. ; Phillips, C. ; Fay, M. F. ; Nishikawa, R. ; Osoba, D. ; Cairncross, J. G. ; Roa, W. ; Wick, W. ; Shi, W. Impact of lymphopenia on survival for elderly patients with glioblastoma: A secondary analysis of the CCTG CE.6 (EORTC 26062-22061, TROG03.01) randomized clinical trial.
Neuro-oncology advances 3 (1 ), vdab153 (2021 ) [10.1093/noajnl/vdab153 ] 2021
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Blobner, J. (First author) ; Kilian, M. ; Tan, C. L. ; Aslan, K. ; Sanghvi, K. ; Meyer, J. ; Fischer, M. ; Jähne, K. ; Breckwoldt, M. O. ; Sahm, F. ; von Deimling, A. ; Bendszus, M. ; Wick, W. ; Platten, M. ; Green, E. ; Bunse, L. (Last author) Comparative evaluation of T-cell receptors in experimental glioma-draining lymph nodes.
Neuro-oncology advances 3 (1 ), vdab147 (2021 ) [10.1093/noajnl/vdab147 ] 2021
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Jayachandran Preetha, C. ; Meredig, H. ; Brugnara, G. ; Mahmutoglu, M. A. ; Foltyn, M. ; Isensee, F. ; Kessler, T. ; Pflüger, I. ; Schell, M. ; Neuberger, U. ; Petersen, J. ; Wick, A. ; Heiland, S. ; Debus, J. ; Platten, M. ; Idbaih, A. ; Brandes, A. A. ; Winkler, F. ; van den Bent, M. J. ; Nabors, B. ; Stupp, R. ; Maier-Hein, K. H. ; Gorlia, T. ; Tonn, J.-C. ; Weller, M. ; Wick, W. ; Bendszus, M. ; Vollmuth, P. Deep-learning-based synthesis of post-contrast T1-weighted MRI for tumour response assessment in neuro-oncology: a multicentre, retrospective cohort study.
The lancet 3 (12 ), e784-e794 (2021 ) [10.1016/S2589-7500(21)00205-3 ] 2021
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Panitz, V. (First author) ; Kon?arevi?, S. ; Sadik, A. ; Friedel, D. ; Bausbacher, T. ; Trump, S. ; Farztdinov, V. ; Schulz, S. ; Sievers, P. ; Schmidt, S. ; Jürgenson, I. ; Jung, S. ; Kuhn, K. ; Pflüger, I. ; Sharma, S. ; Wick, A. ; Pfänder, P. ; Selzer, S. ; Vollmuth, P. ; Sahm, F. ; von Deimling, A. ; Heiland, I. ; Hopf, C. ; Schulz-Knappe, P. ; Pike, I. ; Platten, M. ; Wick, W. ; Opitz, C. (Last author) Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma.
Theranostics 11 (19 ), 9217 - 9233 (2021 ) [10.7150/thno.60679 ] 2021
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Maas, S. L. N. (First author) ; Stichel, D. ; Hielscher, T. ; et al Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated.
Journal of clinical oncology 39 (34 ), 3839-3852 (2021 ) [10.1200/JCO.21.00784 ] 2021
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Sievers, P. (First author) ; Stichel, D. (First author) ; Sill, M. ; Schrimpf, D. ; Sturm, D. ; Selt, F. ; Ecker, J. ; Kazdal, D. ; Miele, E. ; Kranendonk, M. E. G. ; Tops, B. B. J. ; Kohlhof-Meinecke, P. ; Beschorner, R. ; Kramm, C. M. ; Hasselblatt, M. ; Reifenberger, G. ; Capper, D. ; Wesseling, P. ; Stenzinger, A. ; Milde, T. ; Korshunov, A. ; Witt, O. ; Pfister, S. M. ; Wick, W. ; von Deimling, A. ; Jones, D. T. W. ; Sahm, F. (Last author) GOPC:ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types.
Acta neuropathologica 142 (6 ), 1065-1069 (2021 ) [10.1007/s00401-021-02369-1 ] 2021
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Platten, M. (First author) ; Bunse, L. ; Wick, W. (Last author) Brain tumor immunotherapy-Possibilities and challenges of personalization.[Hirntumorimmuntherapie ? Möglichkeiten und Herausforderungen der Personalisierung].
Der Nervenarzt 92 (10 ), 996-1001 (2021 ) [10.1007/s00115-021-01178-x ] 2021
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Le Rhun, E. ; Guckenberger, M. ; Smits, M. ; Dummer, R. ; Bachelot, T. ; Sahm, F. ; Galldiks, N. ; de Azambuja, E. ; Berghoff, A. S. ; Metellus, P. ; Peters, S. ; Hong, Y.-K. ; Winkler, F. ; Schadendorf, D. ; van den Bent, M. ; Seoane, J. ; Stahel, R. ; Minniti, G. ; Wesseling, P. ; Weller, M. ; Preusser, M. ; Board, E. E. ; Committee, E. G. (Collaboration Author) EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with brain metastasis from solid tumours.
Annals of oncology 32 (11 ), 1332-1347 (2021 ) [10.1016/j.annonc.2021.07.016 ] 2021
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Sievers, P. (First author) ; Henneken, S. (First author) ; Blume, C. ; et al Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors.
Acta neuropathologica 142 (5 ), 827-839 (2021 ) [10.1007/s00401-021-02356-6 ] 2021
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Winkler, F. (Last author) Silencing glioblastoma networks to make temozolomide more effective.
Neuro-Oncology 23 (11 ), 1807-1809 (2021 ) [10.1093/neuonc/noab186 ] 2021
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Richter, F. ; Williams, S. K. ; John, K. ; Huber, C. ; Vaslin, C. ; Zanker, H. ; Fairless, R. ; Pichi, K. ; Marhenke, S. ; Vogel, A. ; Dhaen, M.-A. ; Herrmann, S. ; Herrmann, A. ; Pfizenmaier, K. ; Bantel, H. ; Diem, R. ; Kontermann, R. E. ; Fischer, R. The TNFR1 Antagonist Atrosimab Is Therapeutic in Mouse Models of Acute and Chronic Inflammation.
Frontiers in immunology 12 , 705485 (2021 ) [10.3389/fimmu.2021.705485 ] 2021
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Hau, P. ; Frappaz, D. ; Hovey, E. ; McCabe, M. G. ; Pajtler, K. W. ; Wiestler, B. ; Seidel, C. ; Combs, S. E. ; Dirven, L. ; Klein, M. ; Anazodo, A. ; Hattingen, E. ; Hofer, S. ; Pfister, S. M. ; Zimmer, C. ; Kortmann, R.-D. ; Sunyach, M.-P. ; Tanguy, R. ; Effeney, R. ; von Deimling, A. ; Sahm, F. ; Rutkowski, S. ; Berghoff, A. S. ; Franceschi, E. ; Pineda, E. ; Beier, D. ; Peeters, E. ; Gorlia, T. ; Vanlancker, M. ; Bromberg, J. E. C. ; Gautier, J. ; Ziegler, D. S. ; Preusser, M. ; Wick, W. ; Weller, M. Development of Randomized Trials in Adults with Medulloblastoma-The Example of EORTC 1634-BTG/NOA-23.
Cancers 13 (14 ), 3451 (2021 ) [10.3390/cancers13143451 ] 2021
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Platten, M. (First author) ; Bunse, L. ; Wick, W. (Last author) Emerging targets for anticancer vaccination: IDH
ESMO open 6 (4 ), 100214 (2021 ) [10.1016/j.esmoop.2021.100214 ] 2021
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Sokpor, G. ; Kerimoglu, C. ; Nguyen, H. ; Pham, L. ; Rosenbusch, J. ; Wagener, R. ; Nguyen, H. P. ; Fischer, A. ; Staiger, J. F. ; Tuoc, T. Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner.
Frontiers in molecular neuroscience 14 , 687581 (2021 ) [10.3389/fnmol.2021.687581 ] 2021
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Müller, J. (First author) ; Weiler, M. ; Schneeweiss, A. ; Haag, G. M. ; Steindorf, K. ; Wick, W. ; Wiskemann, J. Preventive effect of sensorimotor exercise and resistance training on chemotherapy-induced peripheral neuropathy: a randomised-controlled trial.
British journal of cancer 125 (7 ), 955-965 (2021 ) [10.1038/s41416-021-01471-1 ] 2021
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Tan, A. C. ; Bagley, S. J. ; Wen, P. Y. ; Lim, M. ; Platten, M. ; Colman, H. ; Ashley, D. M. ; Wick, W. ; Chang, S. M. ; Galanis, E. ; Mansouri, A. ; Khagi, S. ; Mehta, M. P. ; Heimberger, A. B. ; Puduvalli, V. K. ; Reardon, D. A. ; Sahebjam, S. ; Simes, J. ; Antonia, S. J. ; Berry, D. ; Khasraw, M. Systematic review of combinations of targeted or immunotherapy in advanced solid tumors.
Journal for ImmunoTherapy of Cancer 9 (7 ), e002459 (2021 ) [10.1136/jitc-2021-002459 ] 2021
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Michalak, M. (First author) ; Kalteis, M. S. ; Ahadova, A. ; Kloor, M. ; Kriegsmann, M. ; Kriegsmann, K. ; Warnken, U. ; Helm, D. ; Kopitz, J. (Last author) Differential Glycosite Profiling?A Versatile Method to Compare Membrane Glycoproteomes
Molecules 26 (12 ), 3564 (2021 ) [10.3390/molecules26123564 ] 2021
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Walbert, T. ; Harrison, R. A. ; Schiff, D. ; Avila, E. K. ; Chen, M. ; Kandula, P. ; Lee, J. W. ; Le Rhun, E. ; Stevens, G. H. J. ; Vogelbaum, M. A. ; Wick, W. ; Weller, M. ; Wen, P. Y. ; Gerstner, E. R. SNO and EANO practice guideline update: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors.
Neuro-Oncology 23 (11 ), 1835-1844 (2021 ) [10.1093/neuonc/noab152 ] 2021
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Kessler, T. (First author) ; Wick, W. (Last author) Oncolytic virotherapy: Potentially a game-changing tumor treatment.
Cancer cell 39 (6 ), 753 - 755 (2021 ) [10.1016/j.ccell.2021.05.014 ] 2021
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Venkataramani, V. (First author) ; Winkler, F. (Last author) Activation of retinal neurons triggers tumour formation in cancer-prone mice
Nature <London> 594 (7862 ), 179 - 180 (2021 ) [10.1038/d41586-021-01353-9 ] 2021
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Friedrich, M. (First author) ; Sankowski, R. ; Bunse, L. ; Kilian, M. ; Green, E. ; Ramallo Guevara, C. ; Pusch, S. ; Poschet, G. ; Sanghvi, K. ; Hahn, M. ; Bunse, T. ; Münch, P. ; Gegner, H. M. ; Sonner, J. ; von Landenberg, A. ; Cichon, F. ; Aslan, K. ; Trobisch, T. ; Schirmer, L. ; Abu-Sammour, D. ; Kessler, T. ; Ratliff, M. ; Schrimpf, D. ; Sahm, F. ; Hopf, C. ; Heiland, D. H. ; Schnell, O. ; Beck, J. ; Böttcher, C. ; Fernandez-Zapata, C. ; Priller, J. ; Heiland, S. ; Gutcher, I. ; Quintana, F. J. ; von Deimling, A. ; Wick, W. ; Prinz, M. ; Platten, M. (Last author) Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas
Nature cancer 2 , 723?740 (2021 ) [10.1038/s43018-021-00201-z ] 2021
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Nasir, A. ; Cardall, A. ; Othman, R. T. ; Nicolaou, N. ; Lourdusamy, A. ; Linke, F. ; Onion, D. ; Ryzhova, M. ; Cameron, H. ; Valente, C. ; Ritchie, A. ; Korshunov, A. ; Pfister, S. M. ; Grabowska, A. M. ; Kerr, I. D. ; Coyle, B. ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma.
Neuro-oncology advances 3 (1 ), 1-12 (2021 ) [10.1093/noajnl/vdab030 ] 2021
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Taranda, J. (First author) ; Turcan, S. (Last author) 3D Whole-Brain Imaging Approaches to Study Brain Tumors
Cancers 13 (8 ), 1897 (2021 ) [10.3390/cancers13081897 ] 2021
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Suwala, A. K. (First author) ; Stichel, D. ; Schrimpf, D. ; Maas, S. L. N. ; Sill, M. ; Dohmen, H. ; Banan, R. ; Reinhardt, A. ; Sievers, P. ; Hinz, F. ; Blattner-Johnson, M. ; Hartmann, C. ; Schweizer, L. ; Boldt, H. B. ; Kristensen, B. W. ; Schittenhelm, J. ; Wood, M. D. ; Chotard, G. ; Bjergvig, R. ; Das, A. ; Tabori, U. ; Hasselblatt, M. ; Korshunov, A. ; Abdullaev, Z. ; Quezado, M. ; Aldape, K. ; Harter, P. ; Snuderl, M. ; Hench, J. ; Frank, S. ; Acker, T. ; Brandner, S. ; Winkler, F. ; Wesseling, P. ; Pfister, S. M. ; Reuss, D. E. ; Wick, W. ; von Deimling, A. ; Jones, D. T. W. ; Sahm, F. (Last author) Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1.
Acta neuropathologica 142 (1 ), 179-189 (2021 ) [10.1007/s00401-021-02302-6 ] 2021
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Doubrovinskaia, S. ; Sahm, F. ; Thier, M. C. ; Bendszus, M. ; Wick, W. ; Seliger, C. ; Kaulen, L. D. Primary CNS lymphoma after CLIPPERS: a case series.
Journal of neurology, neurosurgery, and psychiatry 92 (12 ), 1348-1349 (2021 ) [10.1136/jnnp-2020-325759 ] 2021
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Platten, M. (First author) ; Bunse, L. ; Wick, A. ; Bunse, T. ; Le Cornet, L. ; Harting, I. ; Sahm, F. ; Sanghvi, K. ; Tan, C. L. ; Poschke, I. ; Green, E. ; Justesen, S. ; Behrens, G. A. ; Breckwoldt, M. O. ; Freitag, A. ; Rother, L.-M. ; Schmitt, A. ; Schnell, O. ; Hense, J. ; Misch, M. ; Krex, D. ; Stevanovic, S. ; Tabatabai, G. ; Steinbach, J. P. ; Bendszus, M. ; von Deimling, A. ; Schmitt, M. ; Wick, W. A vaccine targeting mutant IDH1 in newly diagnosed glioma.
Nature <London> 592 (7854 ), 463-468 (2021 ) [10.1038/s41586-021-03363-z ] 2021
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Azorín, D. D. (First author) ; Winkler, F. (Last author) Two routes of direct intercellular communication in brain cancer.
Biochemical journal 478 (6 ), 1283 - 1286 (2021 ) [10.1042/BCJ20200990 ] 2021
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Schnabel, E. (First author) ; Knoll, M. (First author) ; Schwager, C. ; Warta, R. ; Mock, A. ; Campos, B. ; König, L. ; Jungk, C. ; Wick, W. ; Unterberg, A. ; Debus, J. ; Herold-Mende, C. ; Abdollahi, A. (Last author) Prognostic Value of microRNA-221/2 and 17-92 Families in Primary Glioblastoma Patients Treated with Postoperative Radiotherapy
International journal of molecular sciences 22 (6 ), 2960 (2021 ) [10.3390/ijms22062960 ] 2021
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Schmid, D. (First author) ; Warnken, U. ; Latzer, P. ; Hoffmann, D. C. ; Roth, J. ; Kutschmann, S. ; Jaschonek, H. ; Rübmann, P. ; Foltyn, M. ; Vollmuth, P. ; Winkler, F. ; Seliger, C. ; Felix, M. ; Sahm, F. ; Haas, J. ; Reuss, D. ; Bendszus, M. ; Wildemann, B. ; von Deimling, A. ; Wick, W. ; Kessler, T. (Last author) Diagnostic Biomarkers from Proteomic Characterization of Cerebrospinal Fluid in Patients with Brain Malignancies.
Journal of neurochemistry 158 (2 ), 522-538 (2021 ) [10.1111/jnc.15350 ] 2021
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Winkler, F. (Last author) In glioma, all endothelial cells are not created the same.
Neuro-Oncology 23 (6 ), 863-864 (2021 ) [10.1093/neuonc/noab065 ] 2021
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Wick, A. ; Bähr, O. ; Schuler, M. ; Rohrberg, K. S. ; Chawla, S. P. ; Filip, J. ; Schiff, D. ; Heinemann, V. ; Narita, Y. ; Lenz, H.-J. ; Ikeda, M. ; Ando, Y. ; Wick, W. ; Steinbach, J. P. ; Burger, M. C. ; Wenger, K. J. ; Lassen, U. ; Sankhala, K. K. ; Roggia, C. M. ; Genvresse, I. ; Munhoz, C. ; Rentzsch, C. ; Reschke, S. ; Langer, S. ; Wagner, M. ; Kaulfuss, S. ; Cai, C. ; Lagkadinou, E. ; Jeffers, M. ; Pena, C. ; Tabatabai, G. Phase I assessment of safety and therapeutic activity of BAY1436032 in patients with IDH1-mutant solid tumors.
Clinical cancer research 27 (10 ), 2723-2733 (2021 ) [10.1158/1078-0432.CCR-20-4256 ] 2021
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Gramatzki, D. ; Felsberg, J. ; Hentschel, B. ; Wolter, M. ; Schackert, G. ; Westphal, M. ; Regli, L. ; Thon, N. ; Tatagiba, M. ; Wick, W. ; Schlegel, U. ; Krex, D. ; Matschke, J. ; Roth, P. ; Suresh, M. P. ; Kamp, M. A. ; Rushing, E. J. ; Pietsch, T. ; von Deimling, A. ; Sabel, M. ; Loeffler, M. ; Weller, M. ; Reifenberger, G. Telomerase reverse transcriptase promoter mutation- and O6-methylguanine DNA methyltransferase promoter methylation-mediated sensitivity to temozolomide in isocitrate dehydrogenase-wild-type glioblastoma: is there a link?
European journal of cancer 147 , 84 - 94 (2021 ) [10.1016/j.ejca.2021.01.014 ] 2021
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Jung, E. (First author) ; Osswald, M. ; Ratliff, M. ; Dogan, H. ; Xie, R. ; Weil, S. ; Hoffmann, D. C. ; Kurz, F. T. ; Kessler, T. ; Heiland, S. ; von Deimling, A. ; Sahm, F. ; Wick, W. ; Winkler, F. (Last author) Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma.
Nature Communications 12 (1 ), 1014 (2021 ) [10.1038/s41467-021-21117-3 ] 2021
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Koelsche, C. (First author) ; Schrimpf, D. (First author) ; Stichel, D. (First author) ; et al Sarcoma classification by DNA methylation profiling.
Nature Communications 12 (1 ), 498 (2021 ) [10.1038/s41467-020-20603-4 ] 2021
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Berghoff, A. S. (First author) ; Liao, Y. (First author) ; Karreman, M. A. ; Ilhan-Mutlu, A. ; Gunkel, K. ; Sprick, M. ; Eisen, C. ; Kessler, T. ; Osswald, M. ; Wunsche, S. ; Feinauer, M. ; Gril, B. ; Marme, F. ; Michel, L. L. ; Bago-Horvath, Z. ; Sahm, F. ; Becker, N. ; Breckwoldt, M. O. ; Solecki, G. M. ; Gommel, M. ; Huang, L. ; Rübmann, P. ; Thomé, C. ; Ratliff, M. ; Trumpp, A. ; Steeg, P. S. ; Preusser, M. ; Wick, W. ; Winkler, F. (Last author) Identification and characterization of cancer cells that initiate metastases to the brain and other organs.
Molecular cancer research 19 (4 ), 688-701 (2021 ) [10.1158/1541-7786.MCR-20-0863 ] 2021
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Chuntova, P. ; Chow, F. ; Watchmaker, P. ; Galvez, M. ; Heimberger, A. B. ; Newell, E. W. ; Diaz, A. ; DePinho, R. A. ; Li, M. O. ; Wherry, E. J. ; Mitchell, D. ; Terabe, M. ; Wainwright, D. A. ; Berzofsky, J. A. ; Herold-Mende, C. ; Heath, J. R. ; Lim, M. ; Margolin, K. A. ; Chiocca, E. A. ; Kasahara, N. ; Ellingson, B. M. ; Brown, C. ; Chen, Y. ; Fecci, P. ; Reardon, D. A. ; Dunn, G. P. ; Liau, L. M. ; Costello, J. F. ; Wick, W. ; Cloughesy, T. ; Timmer, W. C. ; Wen, P. Y. ; Prins, R. M. ; Platten, M. ; Okada, H. Unique challenges for glioblastoma immunotherapy - Discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology.
Neuro-Oncology 23 (3 ), 356-375 (2021 ) [10.1093/neuonc/noaa277 ] 2021
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Sievers, P. (First author) ; Sill, M. (First author) ; Blume, C. ; Tauziede-Espariat, A. ; Schrimpf, D. ; Stichel, D. ; Reuss, D. E. ; Dogan, H. ; Hartmann, C. ; Mawrin, C. ; Hasselblatt, M. ; Stummer, W. ; Schick, U. ; Hench, J. ; Frank, S. ; Ketter, R. ; Schweizer, L. ; Schittenhelm, J. ; Puget, S. ; Brandner, S. ; Jaunmuktane, Z. ; Küsters, B. ; Abdullaev, Z. ; Pekmezci, M. ; Snuderl, M. ; Ratliff, M. ; Herold-Mende, C. ; Unterberg, A. ; Aldape, K. ; Ellison, D. W. ; Wesseling, P. ; Reifenberger, G. ; Wick, W. ; Perry, A. ; Varlet, P. ; Pfister, S. M. ; Jones, D. T. W. ; von Deimling, A. ; Sahm, F. (Last author) Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1
Acta neuropathologica 141 (2 ), 281-290 (2021 ) [10.1007/s00401-020-02247-2 ] 2021
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Xie, R. (First author) ; Kessler, T. ; Grosch, J. ; Hai, L. ; Venkataramani, V. ; Huang, L. ; Hoffmann, D. C. ; Solecki, G. ; Ratliff, M. ; Schlesner, M. ; Wick, W. ; Winkler, F. (Last author) Tumor cell network integration in glioma represents a stemness feature
Neuro-Oncology 23 (5 ), 757-769 (2021 ) [10.1093/neuonc/noaa275 ] 2021
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Weller, M. ; van den Bent, M. ; Preusser, M. ; Le Rhun, E. ; Tonn, J. C. ; Minniti, G. ; Bendszus, M. ; Balana, C. ; Chinot, O. ; Dirven, L. ; French, P. ; Hegi, M. E. ; Jakola, A. S. ; Platten, M. ; Roth, P. ; Rudà, R. ; Short, S. ; Smits, M. ; Taphoorn, M. J. B. ; von Deimling, A. ; Westphal, M. ; Soffietti, R. ; Reifenberger, G. ; Wick, W. (Last author) EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood.
Nature reviews / Clinical oncology 18 (3 ), 170-186 (2021 ) [10.1038/s41571-020-00447-z ] 2021
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Feinauer, M. (First author) ; Schneider, S. W. ; Berghoff, A. S. ; Robador, J. R. ; Tehranian, C. ; Karreman, M. A. ; Venkataramani, V. ; Solecki, G. ; Grosch, J. K. ; Frey, K. ; Kovalchuk, B. ; Mayer, F. T. ; Fischer, M. ; O. Breckwoldt, M. ; Brune, M. ; Schwab, Y. ; Wick, W. ; Bauer, A. T. ; Winkler, F. (Last author) Local blood coagulation drives cancer cell arrest and brain metastasis in a mouse model
Blood 137 (9 ), 1219-1232 (2021 ) [10.1182/blood.2020005710 ] 2021
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Roth, P. ; Pace, A. ; Le Rhun, E. ; Weller, M. ; Ay, C. ; Cohen-Jonathan Moyal, E. ; Coomans, M. ; Giusti, R. ; Jordan, K. ; Nishikawa, R. ; Winkler, F. ; Hong, J. T. ; Ruda, R. ; Villà, S. ; Taphoorn, M. J. B. ; Wick, W. ; Preusser, M. ; Board, E. E. (Collaboration Author) ; Committee, E. G. (Collaboration Author) Neurological and vascular complications of primary and secondary brain tumours: EANO-ESMO Clinical Practice Guidelines for prophylaxis, diagnosis, treatment and follow-up.
Annals of oncology 32 (2 ), 171-182 (2021 ) [10.1016/j.annonc.2020.11.003 ] 2021
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Suwala, A. K. (First author) ; Stichel, D. ; Schrimpf, D. ; Kloor, M. ; Wefers, A. K. ; Reinhardt, A. ; Maas, S. L. N. ; Kratz, C. P. ; Schweizer, L. ; Hasselblatt, M. ; Snuderl, M. ; Abedalthagafi, M. S. J. ; Abdullaev, Z. ; Monoranu, C. M. ; Bergmann, M. ; Pekrun, A. ; Freyschlag, C. ; Aronica, E. ; Kramm, C. M. ; Hinz, F. ; Sievers, P. ; Korshunov, A. ; Kool, M. ; Pfister, S. M. ; Sturm, D. ; Jones, D. T. W. ; Wick, W. ; Unterberg, A. ; Hartmann, C. ; Dodgshun, A. ; Tabori, U. ; Wesseling, P. ; Sahm, F. ; von Deimling, A. ; Reuß, D. (Last author) Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis.
Acta neuropathologica 141 (1 ), 85-100 (2021 ) [10.1007/s00401-020-02243-6 ] 2021
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Sievers, P. (First author) ; Sill, M. ; Schrimpf, D. ; Stichel, D. ; Reuß, D. ; Sturm, D. ; Hench, J. ; Frank, S. ; Krskova, L. ; Vicha, A. ; Zapotocky, M. ; Bison, B. ; Castel, D. ; Grill, J. ; Debily, M.-A. ; Harter, P. N. ; Snuderl, M. ; Kramm, C. M. ; Reifenberger, G. ; Korshunov, A. ; Jabado, N. ; Wesseling, P. ; Wick, W. ; Solomon, D. A. ; Perry, A. ; Jacques, T. S. ; Jones, C. ; Witt, O. ; Pfister, S. ; von Deimling, A. ; Jones, D. (Last author) ; Sahm, F. (Last author) A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR.
Neuro-Oncology 23 (1 ), 34-43 (2021 ) [10.1093/neuonc/noaa251 ] 2021
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Hahn, A. ; Bode, J. ; Alexander, A. ; Karimian-Jazi, K. ; Schregel, K. ; Schwarz, D. ; Sommerkamp, A. C. ; Krüwel, T. ; Abdollahi, A. ; Wick, W. ; Platten, M. ; Bendszus, M. ; Tews, B. ; Kurz, F. T. ; Breckwoldt, M. (Last author) Large-scale characterization of the microvascular geometry in development and disease by tissue clearing and quantitative ultramicroscopy.
Journal of cerebral blood flow & metabolism 41 (7 ), 1536-1546 (2021 ) [10.1177/0271678X20961854 ] 2021
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Park, J.-W. ; Sahm, F. ; Steffl, B. ; Arrillaga-Romany, I. ; Cahill, D. ; Monje, M. ; Herold-Mende, C. ; Wick, W. ; Turcan, ?. TERT and DNMT1 expression predict sensitivity to decitabine in gliomas.
Neuro-Oncology 23 (1 ), 76-87 (2021 ) [10.1093/neuonc/noaa207 ] 2021
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Venkataramani, V. (First author) ; Tanev, D. I. ; Kuner, T. ; Wick, W. ; Winkler, F. (Last author) Synaptic Input to Brain Tumors: Clinical Implications.
Neuro-Oncology 23 (1 ), 23-33 (2021 ) [10.1093/neuonc/noaa158 ] 2021
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