Publications

[1] Horvat N*, Chocarro S*, Marques O, Bauer T, Qiu R, Diaz-Jimenez A, Helm B, Chen Y, Sawall S, Sparla R, Su L, Klingmüller U, Barz M, Hentze M*, Sotillo R*#, Muckenthaler M*#. Super Paramagnetic Iron Oxide Nanoparticles reprogram the tumor microenvironment and reduce lung cancer regrowth after crizotinib treatment. ACS Nano, in press.

[2] C. Durfee, N.A. Temiz, R. Levin-Klein, P.P. Argyris, L. Alsøe, S. Carracedo, A.A. de la Vega, J. Proehl, A.M. Holzhauer, Z.J. Seeman, X. Liu, Y.-H.T. Lin, R.I. Vogel, R. Sotillo, H. Nilsen, R.S. Harris, Human APOBEC3B promotes tumor development in vivo including signature mutations and metastases. Cell Reports Medicine (2023)

[3] F. Pan, S. Chocarro, M. Ramos, Y. Chen, A.A. de la Vega, K. Somogyi, R. Sotillo. FOXM1 is critical for the fitness recovery of chromosomally unstable cells. Cell Death Disease (2023)

[4] S. Kandala, M. Ramos, L.V. von Voithenberg, A. Diaz-Jimenez, S. Chocarro, J. Keding, B. Brors, C.D. Imbusch, R. Sotillo, Chronic chromosome instability induced by Plk1 results in immune suppression in breast cancer. Cell Reports (2023)

[5] B. Raach, N. Bundgaard, M.J. Haase, J. Starruß, R. Sotillo, M.L. Stanifer, F. Graw. Influence of cell type specific infectivity and tissue composition on SARS-CoV-2 infection dynamics within human airway epithelium. PLOS Computational Biology (2023)

[6] A.A. de la Vega, N.A. Temiz, R. Tasakis, K. Somogyi, L. Salgueiro, E. Zimmer, M. Ramos, A. Diaz-Jimenez, S. Chocarro, M. Fernández-Vaquero, B. Stefanovska, E. Reuveni, U. Ben-David, A. Stenzinger, T. Poth, M. Heikenwälder, N. Papavasiliou, R.S. Harris, R. Sotillo. Acute expression of human APOBEC3B in mice results in RNA editing and lethality. Genome Biology (2023)

[7] A.-S. Lamort, J.C. Kaiser, M.A.A. Pepe, I. Lilis, G. Ntaliarda, K. Somogyi, M. Spella, S.J. Behrend, G.A. Giotopoulou, W. Kujawa, M. Lindner, I. Koch, R.A. Hatz, J. Behr, R. Sotillo, A.C. Schamberger, G.T. Stathopoulos, Prognostic phenotypes of early-stage lung adenocarcinoma. European Respiratory Journal (2022).

[8] L. Salgueiro, S. Kummer, V. Sonntag-Buck, A. Weiß, M.A. Schneider, H.-G. Kräusslich, R. Sotillo. Generation of Human Lung Organoid Cultures from Healthy and Tumor Tissue to Study Infectious Diseases. Journal of Virology (2022)

[9] Y. Chen, R. Toth, S. Chocarro, D. Weichenhan, J. Hey, P. Lutsik, S. Sawall, G.T. Stathopoulos, C. Plass, R. Sotillo. Club cells employ regeneration mechanisms during lung tumorigenesis. Nature Communications (2022)

[10] K. Alikhanyan, Y. Chen, K. Somogyi, S. Kraut, R. Sotillo. Mad2 Induced Aneuploidy Contributes to Eml4-Alk Driven Lung Cancer by Generating an Immunosuppressive Environment. Cancers (2021)

[11] T.A. Bauer, N.K. Horvat, O. Marques, S. Chocarro, C. Mertens, S. Colucci, S. Schmitt, L.M. Carrella, S. Morsbach, K. Koynov, F. Fenaroli, P. Blümler, M. Jung, R. Sotillo, M.W. Hentze, M.U. Muckenthaler, M. Barz. Core Cross‐Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages. Adv Healthc Mater (2021)

[12] L. Salgueiro, C. Buccitelli, K. Rowald, K. Somogyi, S. Kandala, J.O. Korbel, R. Sotillo, Acquisition of chromosome instability is a mechanism to evade oncogene addiction. EMBO Molecular Medicine (2020)

[13] Spella M, Lilis I, Pepe MA, Chen Y, Armaka M, Lamort AS, Zazara DE, Roumelioti F, Vreka M, Kanellakis NI, Wagner DE, Giannou AD, Armenis V, Arendt KA, Klotz LV, Toumpanakis D, Karavana V, Zakynthinos SG, Giopanou I, Marazioti A, Aidinis V, Sotillo R*, Stathopoulos GT*. Club cells form lung adenocarcinomas and maintain the alveoli of adult mice. * co-last authors. Elife (2019)

[14] G. de Cárcer, S.V. Venkateswaran, L. Salgueiro, A.E. Bakkali, K. Somogyi, K. Rowald, P. Montañés, M. Sanclemente, B. Escobar, A. de Martino, N. McGranahan, M. Malumbres, R. Sotillo. Plk1 overexpression induces chromosomal instability and suppresses tumor development. Nature Communications (2018)