Publications 2018
EGFR heterogeneity and implications for therapeutic intervention in glioblastoma.
Neuro-Oncology 20(6), 743 - 752 (2018) [10.1093/neuonc/nox191]
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The mechanics of metastatic seeding.
Nature cell biology 20(8), 860 - 862 (2018) [10.1038/s41556-018-0162-8]
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Chemical exchange saturation transfer MRI serves as predictor of early progression in glioblastoma patients.
OncoTarget 9(47), 28772-28783 (2018) [10.18632/oncotarget.25594]
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Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T.
Neuro-Oncology 20(12), 1661 - 1671 (2018) [10.1093/neuonc/noy073]
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cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant.
Acta neuropathologica 135(4), 639 - 642 (2018) [10.1007/s00401-018-1826-y]
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Perspectives of immunotherapy in isocitrate dehydrogenase-mutant gliomas.
Current opinion in oncology 30(6), 368-374 (2018) [10.1097/CCO.0000000000000478]
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Correlated light and electron microscopy of cell division in large marine oocytes, eggs, and embryos.
Methods in cell biology 145, 293-313 (2018) [10.1016/bs.mcb.2018.03.031]
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Voxel-wise radiogenomic mapping of tumor location with key molecular alterations in patients with glioma.
Neuro-Oncology 20(11), 1517 - 1524 (2018) [10.1093/neuonc/noy134]
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Post-chemoradiation volumetric response predicts survival in newly diagnosed glioblastoma treated with radiation, temozolomide, and bevacizumab or placebo.
Neuro-Oncology 20(11), 1525 - 1535 (2018) [10.1093/neuonc/noy064]
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Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence.
Acta neuropathologica 135(6), 955 - 963 (2018) [10.1007/s00401-018-1844-9]
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Gd contrast administration is dispensable in patients with MS without new T2 lesions on follow-up MRI.
Neurology 5(5), e480 (2018) [10.1212/NXI.0000000000000480]
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Nonmeasurable Speckled Contrast-Enhancing Lesions Appearing During Course of Disease Are Associated With IDH Mutation in High-Grade Astrocytoma Patients.
International journal of radiation oncology, biology, physics 102(5), 1472 - 1480 (2018) [10.1016/j.ijrobp.2018.07.2004]
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Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p.1
Acta neuropathologica 136(6), 975-978 (2018) [10.1007/s00401-018-1924-x]
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First results on the DCVax phase III trial: raising more questions than providing answers.
Neuro-Oncology 20(10), 1283 - 1284 (2018) [10.1093/neuonc/noy125]
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Understanding and Treating Glioblastoma.
Neurologic clinics 36(3), 485 - 499 (2018) [10.1016/j.ncl.2018.04.006]
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Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma.
Acta neuropathologica 136(5), 793-803 (2018) [10.1007/s00401-018-1905-0]
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Associations of anticoagulant use with outcome in newly diagnosed glioblastoma.
European journal of cancer 101, 95 - 104 (2018) [10.1016/j.ejca.2018.06.029]
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Leukaemia follows a blood-vessel track to enter the nervous system
Nature <London> 560(7716), 35 - 36 (2018) [10.1038/d41586-018-05693-x]
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Treatment of glioblastoma in adults.
Therapeutic advances in neurological disorders 11, 1756286418790452 (2018) [10.1177/1756286418790452]
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New glioblastoma heterogeneity atlas - a shared resource.
Nature reviews / Neurology 14(8), 453 - 454 (2018) [10.1038/s41582-018-0038-3]
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Validation of post-operative residual contrast enhancing tumor volume as an independent prognostic factor for overall survival in newly diagnosed glioblastoma.
Neuro-Oncology 20(9), 1240 - 1250 (2018) [10.1093/neuonc/noy053]
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A PRDX1-p38? heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas.
International journal of cancer 143(5), 1176 - 1187 (2018) [10.1002/ijc.31404]
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The Evolving Landscape of Brain Metastasis.
Trends in cancer 4(3), 176 - 196 (2018) [10.1016/j.trecan.2018.01.003]
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Novel, improved grading system(s) for IDH-mutant astrocytic gliomas.
Acta neuropathologica 136(1), 153 - 166 (2018) [10.1007/s00401-018-1849-4]
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Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.
Acta neuropathologica 136(2), 181 - 210 (2018) [10.1007/s00401-018-1879-y]
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Vessel radius mapping in an extended model of transverse relaxation.
Magnetic resonance materials in physics, biology and medicine 31(4), 531 - 551 (2018) [10.1007/s10334-018-0677-9]
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Regimen of procarbazine, lomustine, and vincristine versus temozolomide for gliomas.
Cancer 124(13), 2674 - 2676 (2018) [10.1002/cncr.31371]
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Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation-the NCT Neuro Master Match (N2M2) pilot study.
Neuro-Oncology 20(6), 826 - 837 (2018) [10.1093/neuonc/nox216]
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Radiomic subtyping improves disease stratification beyond key molecular, clinical, and standard imaging characteristics in patients with glioblastoma.
Neuro-Oncology 20(6), 848 - 857 (2018) [10.1093/neuonc/nox188]
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Vaccine Strategies in Gliomas.
Current treatment options in neurology 20(5), 11 (2018) [10.1007/s11940-018-0498-1]
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Impact of 18F-FET PET on Target Volume Definition and Tumor Progression of Recurrent High Grade Glioma Treated with Carbon-Ion Radiotherapy.
Scientific reports 8(1), 7201 (2018) [10.1038/s41598-018-25350-7]
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Inhibition of CD95/CD95L (FAS/FASLG) Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma.
Molecular cancer research 16(5), 767 - 776 (2018) [10.1158/1541-7786.MCR-17-0563]
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Anti-Angiogenics: Their Role in the Treatment of Glioblastoma.
Oncology research and treatment 41(4), 181 - 186 (2018) [10.1159/000488258]
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Radiologic progression of glioblastoma under therapy-an exploratory analysis of AVAglio.
Neuro-Oncology 20(4), 557 - 566 (2018) [10.1093/neuonc/nox162]
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Hemodynamic Forces Tune the Arrest, Adhesion, and Extravasation of Circulating Tumor Cells.
Developmental cell 45(1), 33 - 52.e12 (2018) [10.1016/j.devcel.2018.02.015]
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New Directions in the Treatment of Glioblastoma.
Seminars in neurology 38(1), 050 - 061 (2018) [10.1055/s-0038-1623534]
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Neuro-Oncology
Seminars in neurology 38(01), 003 - 004 (2018) [10.1055/s-0038-1635105]
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Increased Delay Between Gadolinium Chelate Administration and T1-Weighted Magnetic Resonance Imaging Acquisition Increases Contrast-Enhancing Tumor Volumes and T1 Intensities in Brain Tumor Patients.
Investigative radiology 53(4), 223 - 228 (2018) [10.1097/RLI.0000000000000432]
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Toward Precision Medicine in Brain Metastases.
Seminars in neurology 38(1), 095 - 103 (2018) [10.1055/s-0038-1627469]
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The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033.
Acta neuropathologica 135(4), 601 - 615 (2018) [10.1007/s00401-018-1810-6]
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cIMPACT-NOW update 1: Not Otherwise Specified (NOS) and Not Elsewhere Classified (NEC).
Acta neuropathologica 135(3), 481 - 484 (2018) [10.1007/s00401-018-1808-0]
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Rapid detection of 2-hydroxyglutarate in frozen sections of IDH mutant tumors by MALDI-TOF mass spectrometry.
Acta Neuropathologica Communications 6(1), 21 (2018) [10.1186/s40478-018-0523-3]
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Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation.
Neuro-Oncology 20(3), 367 - 379 (2018) [10.1093/neuonc/nox160]
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Glioblastoma in elderly patients: solid conclusions built on shifting sand?
Neuro-Oncology 20(2), 174 - 183 (2018) [10.1093/neuonc/nox133]
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Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07).
Neuro-Oncology 20(3), 400 - 410 (2018) [10.1093/neuonc/nox155]
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Drug Repositioning Meets Precision in Glioblastoma.
Clinical cancer research 24(2), 256 - 258 (2018) [10.1158/1078-0432.CCR-17-2989]
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