Publications 2022
Journal Article
Assessment of Body Mass Index, Polygenic Risk Score, and Development of Colorectal Cancer.
JAMA network open 5(12), e2248447 - (2022) [10.1001/jamanetworkopen.2022.48447]
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Journal Article
The power of a healthy lifestyle for cancer prevention: the example of colorectal cancer.
Cancer biology & medicine 19(11), 1586 - 1597 (2022) [10.20892/j.issn.2095-3941.2022.0397]
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Journal Article
Differences in the gut microbiome by physical activity and BMI among colorectal cancer patients.
American journal of cancer research 12(10), 4789-4801 (2022)
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Journal Article (Letter)
Indications of substantial delay of colorectal cancer diagnoses due to COVID-19 in Germany.
The lancet / Regional health. Europe 23, 100543 (2022) [10.1016/j.lanepe.2022.100543]
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Dissertation / PhD Thesis
Colorectal cancer screening in European countries: comparativeanalysis of screening offers, utilization rates, and progress in cancer control
Dissertation, Universität Heidelberg, 2022
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Dissertation / PhD Thesis
Inpatient rehabilitation among colorectal cancer patients: utilization and association with health related outcomes
Dissertation, Universität Heidelberg, 2022
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Dissertation / PhD Thesis
Risk stratification for colorectal cancer screening using epigenetic signatures
Dissertation, Universität Heidelberg, 2022
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Journal Article
Change Toward Healthier Lifestyles Is Associated With Better Health-Related Quality of Life in Long-Term Colorectal Cancer Survivors.
Journal of the National Comprehensive Cancer Network 20(11), 1233 - 1243.e10 (2022) [10.6004/jnccn.2022.7049]
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Journal Article
Assessing performance of the Healthcare Access and Quality Index, overall and by select age groups, for 204 countries and territories, 1990-2019: a systematic analysis from the Global Burden of Disease Study 2019.
The lancet <London> / Global health 10(12), e1715-e1743 (2022) [10.1016/S2214-109X(22)00429-6]
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Journal Article
Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2·5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019.
The lancet / Planetary health 6(7), e586 - e600 (2022) [10.1016/S2542-5196(22)00122-X]
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Journal Article
Occupation and SARS-CoV-2 infection risk among 108 960 workers during the first pandemic wave in Germany.
Scandinavian journal of work, environment & health 48(6), 446 - 456 (2022) [10.5271/sjweh.4037]
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Journal Article
Burden of non-communicable diseases among adolescents aged 10-24 years in the EU, 1990-2019: a systematic analysis of the Global Burden of Diseases Study 2019.
The lancet child & adolescent health 6(6), 367 - 383 (2022) [10.1016/S2352-4642(22)00073-6]
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Journal Article
Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study.
The BMJ 376, e068208 (2022) [10.1136/bmj-2021-068208]
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Journal Article
The assessment of cognitive function in the German National Cohort (NAKO) ? Associations of demographics and psychiatric symptoms with cognitive test performance
The world journal of biological psychiatry 17, 1 - 15 (2022) [10.1080/15622975.2021.2011408]
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Journal Article
Increase in mental disorders during the COVID-19 pandemic?the role of occupational and financial strains. An analysis of the German National Cohort (NAKO) Study
Deutsches A?rzteblatt international 119, 179-187 (2022) [10.3238/arztebl.m2022.0133]
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Journal Article
Lifetime and current depression in the German National Cohort (NAKO)
The world journal of biological psychiatry 17, 1 - 16 (2022) [10.1080/15622975.2021.2014152]
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Journal Article
Efficacy and Safety of a Personalized Vitamin D3 Loading Dose Followed by Daily 2000 IU in Colorectal Cancer Patients with Vitamin D Insufficiency: Interim Analysis of a Randomized Controlled Trial.
Nutrients 14(21), 4546 (2022) [10.3390/nu14214546]
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Journal Article
Comparison of discrimination performance of 11 lung cancer risk models for predicting lung cancer in a prospective cohort of screening-age adults from Germany followed over 17 years.
Lung cancer 174, 83 - 90 (2022) [10.1016/j.lungcan.2022.10.011]
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Journal Article
Common variability in oestrogen-related genes and pancreatic ductal adenocarcinoma risk in women
Scientific reports 12(1), 18100 (2022) [10.1038/s41598-022-22973-9]
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Journal Article (Review Article)
Vitamin D-Binding Protein, Bioavailable, and Free 25(OH)D, and Mortality: A Systematic Review and Meta-Analysis.
Nutrients 14(19), 3894 (2022) [10.3390/nu14193894]
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Journal Article
Changes in aortic diameter induced by weight loss: The HELENA trial- whole-body MR imaging in a dietary intervention trial.
Frontiers in physiology 13, 976949 (2022) [10.3389/fphys.2022.976949]
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Journal Article (Erratum/Correction)
Erratum to ?Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology? Medical Image Analysis, Volume 79, July 2022, 102474
Medical image analysis 82, 102622 (2022) [10.1016/j.media.2022.102622]
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Journal Article
Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study
British journal of sports medicine 56, 1157?1170 (2022) [10.1136/bjsports-2021-105132]
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Journal Article
Association of longitudinal repeated measurements of frailty index with mortality: Cohort study among community-dwelling older adults
EClinicalMedicine 53, 101630 (2022) [10.1016/j.eclinm.2022.101630]
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Journal Article
Associations of individual and combined physical activity and body mass index groups with pro-inflammatory biomarkers among colorectal cancer patients.
Cancer epidemiology, biomarkers & prevention 31(12), 2148-2156 (2022) [10.1158/1055-9965.EPI-22-0681]
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Journal Article
Derivation and validation of an epigenetic frailty risk score in population-based cohorts of older adults.
Nature Communications 13(1), 5269 (2022) [10.1038/s41467-022-32893-x]
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Journal Article
Consistent Inverse Associations of Total, 'Bioavailable', Free, and 'Non-Bioavailable' Vitamin D with Incidence of Diabetes among Older Adults with Lower Baseline HbA1c (?6%) Levels.
Nutrients 14(16), 3282 (2022) [10.3390/nu14163282]
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Journal Article
Predictive polygenic score for outcome after first-line oxaliplatin-based chemotherapy in colorectal cancer patients using supervised principal component analysis.
Cancer epidemiology, biomarkers & prevention 31(11), 2087-2091 (2022) [10.1158/1055-9965.EPI-22-0320]
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Journal Article
Treatment Costs of Colorectal Cancer by Sex and Age: Population-Based Study on Health Insurance Data from Germany.
Cancers 14(15), 3836 (2022) [10.3390/cancers14153836]
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Journal Article
Assessment of a Serum Microrna Risk Score for Colorectal Cancer among Participants of Screening Colonoscopy at Various Stages of Colorectal Carcinogenesis.
Cells 11(15), 2462 (2022) [10.3390/cells11152462]
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Journal Article (Letter)
A serum microRNA signature for enhanced selection of people for lung cancer screening.
Cancer communications 42(11), 1222-1225 (2022) [10.1002/cac2.12346]
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Journal Article
Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer.
Nature genetics 54(8), 1167-1177 (2022) [10.1038/s41588-022-01115-x]
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Journal Article
Clinical and sociodemographic determinants of disease-specific health-related quality of life in long-term breast cancer survivors.
Journal of cancer research and clinical oncology 148(12), 3461-3473 (2022) [10.1007/s00432-022-04204-w]
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Journal Article
Overall and stage-specific survival of patients with screen-detected colorectal cancer in European countries: A population-based study in 9 countries.
The lancet / Regional health. Europe 21, 100458 (2022) [10.1016/j.lanepe.2022.100458]
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Journal Article
Impact of demographic changes and screening colonoscopy on long-term projection of incident colorectal cancer cases in Germany: A modelling study.
The lancet / Regional health. Europe 20, 100451 (2022) [10.1016/j.lanepe.2022.100451]
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Journal Article (Editorial)
Vitamin D3 for reducing mortality from cancer and other outcomes before, during and beyond the COVID-19 pandemic: A plea for harvesting low-hanging fruit.
Cancer communications 42(8), 679-682 (2022) [10.1002/cac2.12328]
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Journal Article
Alcohol consumption, polygenic risk score, and early- and late-onset colorectal cancer risk.
EClinicalMedicine 49, 101460 (2022) [10.1016/j.eclinm.2022.101460]
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Journal Article
Distinct reproductive risk profiles for intrinsic-like breast cancer subtypes: pooled analysis of population-based studies.
Journal of the National Cancer Institute 114(12), 1706-1719 (2022) [10.1093/jnci/djac117]
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Journal Article
Combined performance of fecal immunochemical tests and a genetic risk score for advanced neoplasia detection.
Cancer Prevention Research 15(8), 543-552 (2022) [10.1158/1940-6207.CAPR-21-0552]
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Journal Article
Survival trends of patients with non?metastatic gastric adenocarcinoma in the US and European countries: the impact of decreasing resection rates
Cancer communications 42(7), 648-662 (2022) [10.1002/cac2.12318]
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Journal Article
Pre-surgery adhesion molecules and angiogenesis biomarkers are differently associated with outcomes in colon and rectal cancer: Results from the ColoCare Study.
Cancer epidemiology, biomarkers & prevention 31(8), 1650-1660 (2022) [10.1158/1055-9965.EPI-22-0092]
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Journal Article
Identifying colorectal cancer caused by biallelic MUTYH pathogenic variants using tumor mutational signatures
Nature Communications 13(1), 3254 (2022) [10.1038/s41467-022-30916-1]
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Journal Article
Associations of DNA methylation algorithms of aging and cancer risk: Results from a prospective cohort study.
EBioMedicine 81, 104083 (2022) [10.1016/j.ebiom.2022.104083]
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Journal Article
Reproductive factors and colorectal cancer risk: A Population-based case-control study.
JNCI cancer spectrum 6(4), pkac042 (2022) [10.1093/jncics/pkac042]
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Journal Article
Genome-Wide Interaction Analysis of Genetic Variants with Menopausal Hormone Therapy for Colorectal Cancer Risk.
Journal of the National Cancer Institute 114(8), 1135-1148 (2022) [10.1093/jnci/djac094]
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Journal Article
Higher vitamin B6 status is associated with improved survival among patients with stage I-III colorectal cancer.
The American journal of clinical nutrition 116(2), 303-313 (2022) [10.1093/ajcn/nqac090]
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Journal Article
Benchmarking weakly-supervised deep learning pipelines for whole slide classification in computational pathology.
Medical image analysis 79, 102474 (2022) [10.1016/j.media.2022.102474]
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Journal Article
Proportion and stage distribution of screen-detected and non-screen-detected colorectal cancer in nine European countries: an international, population-based study.
The lancet / Gastroenterology & Hepatology 7(8), 711-723 (2022) [10.1016/S2468-1253(22)00084-X]
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Journal Article
Response to Hawwash et al.
The American journal of gastroenterology 117(5), 812 - 813 (2022) [10.14309/ajg.0000000000001714]
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Journal Article
Incorporation of functional status, frailty, comorbidities and comedication in prediction models for colorectal cancer survival.
International journal of cancer 151(4), 539-552 (2022) [10.1002/ijc.34036]
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Journal Article (Review Article)
Vitamin D food fortification in European countries: the underused potential to prevent cancer deaths.
European journal of epidemiology 37(4), 309-320 (2022) [10.1007/s10654-022-00867-4]
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Journal Article
Potential of Inflammatory Protein Signatures for Enhanced Selection of People for Lung Cancer Screening
Cancers 14(9), 2146 (2022) [10.3390/cancers14092146]
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Journal Article
Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study.
eLife 11, e75374 (2022) [10.7554/eLife.75374]
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Journal Article
Diabetes mellitus in relation to colorectal tumor molecular subtypes: A pooled analysis of more than 9000 cases.
International journal of cancer 151(3), 348-36 (2022) [10.1002/ijc.34015]
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Journal Article
Swarm learning for decentralized artificial intelligence in cancer histopathology.
Nature medicine 28(6), 1232-1239 (2022) [10.1038/s41591-022-01768-5]
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Journal Article
Intake Patterns of Specific Alcoholic Beverages by Prostate Cancer Status.
Cancers 14(8), 1981 (2022) [10.3390/cancers14081981]
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Journal Article
Beyond GWAS of Colorectal Cancer: Evidence of Interaction with Alcohol Consumption and Putative Causal Variant for the 10q24.2 Region.
Cancer epidemiology, biomarkers & prevention 31(5), 1077-1089 (2022) [10.1158/1055-9965.EPI-21-1003]
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Journal Article
Associations between Genetic Variants and Blood Biomarkers of One-Carbon Metabolism in Postmenopausal Women from the Women's Health Initiative Observational Study.
The journal of nutrition 152(4), 1099 - 1106 (2022) [10.1093/jn/nxab444]
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Journal Article
Vitamin D-binding protein, total, 'non-bioavailable', bioavailable, and free 25-hydroxyvitamin D, and mortality in a large population-based cohort of older adults.
Journal of internal medicine 292(3), 463-476 (2022) [10.1111/joim.13494]
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Journal Article
Incidence and survival estimates for patients with myelodysplastic syndrome in the early 21st century: no evidence of improvement over time.
Leukemia and lymphoma 63(8), 1964-1969 (2022) [10.1080/10428194.2022.2053529]
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Journal Article
Risk of Gynecological Cancers in Cholecystectomized Women: A Large Nationwide Cohort Study.
Cancers 14(6), 1484 (2022) [10.3390/cancers14061484]
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Journal Article
Correlation of Repeat Measurements of 27 Candidate Protein Markers for Colorectal Cancer Screening Taken Three Years and Multiple Freeze-Thaw Cycles Apart.
Life 12(3), 359 (2022) [10.3390/life12030359]
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Journal Article
Risk of Colorectal Cancer Associated With Lifetime Excess Weight.
JAMA oncology 8(5), 730-737 (2022) [10.1001/jamaoncol.2022.0064]
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Journal Article
Accounting for EGFR Mutations in Epidemiologic Analyses of Non-Small Cell Lung Cancers: Examples Based on the International Lung Cancer Consortium Data.
Cancer epidemiology, biomarkers & prevention 31(3), cebp.0747.2021 - (2022) [10.1158/1055-9965.EPI-21-0747]
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Journal Article
Red and Processed Meat Intake, Polygenic Risk Score, and Colorectal Cancer Risk.
Nutrients 14(5), 1077 (2022) [10.3390/nu14051077]
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Journal Article
Artificial intelligence for detection of microsatellite instability in colorectal cancer-a multicentric analysis of a pre-screening tool for clinical application.
ESMO open 7(2), 100400 (2022) [10.1016/j.esmoop.2022.100400]
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Journal Article
Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score.
Prostate cancer and prostatic diseases 25(4), 755-761 (2022) [10.1038/s41391-022-00497-7]
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Journal Article
Rare germline copy number variants (CNVs) and breast cancer risk.
Communications biology 5(1), 65 (2022) [10.1038/s42003-021-02990-6]
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Journal Article
Variation of positive predictive values of fecal immunochemical tests by polygenic risk score in a large screening cohort.
Clinical and translational gastroenterology 13(3), e00458 (2022) [10.14309/ctg.0000000000000458]
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Journal Article
Risk Stratification for Early-Onset Colorectal Cancer Using a Combination of Genetic and Environmental Risk Scores: An International Multi-Center Study.
Journal of the National Cancer Institute 114(4), 528-539 (2022) [10.1093/jnci/djac003]
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Journal Article
Association of circulating leukocyte telomere length with survival in patients with colorectal cancer.
Journal of geriatric oncology 13(4), 480-485 (2022) [10.1016/j.jgo.2021.12.008]
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Journal Article
Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Breast cancer research 24(1), 2 (2022) [10.1186/s13058-021-01484-x]
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Journal Article
Genome-wide association study of mitochondrial copy number.
Human molecular genetics 31(8), 1346-1355 (2022) [10.1093/hmg/ddab341]
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Journal Article
Associations of body mass index at different ages with early-onset colorectal cancer.
Gastroenterology 162(4), 1088-1097.e3 (2022) [10.1053/j.gastro.2021.12.239]
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Journal Article
Genetic variants associated with circulating C?reactive protein levels and colorectal cancer survival: Sex? and lifestyle factors? specific associations
International journal of cancer 150(9), 1447-1454 (2022) [10.1002/ijc.33897]
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Journal Article
Model Based Evaluation of Long?Term Efficacy of Existing and Alternative Colorectal Cancer Screening Offers: A Case Study for Germany
International journal of cancer 150(9), 1471-1480 (2022) [10.1002/ijc.33894]
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Journal Article
Quality of life, distress, and posttraumatic growth 5 years after colorectal cancer diagnosis according to history of inpatient rehabilitation.
Journal of cancer research and clinical oncology 148(11), 3015-3028 (2022) [10.1007/s00432-021-03865-3]
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Journal Article
Comorbidities, Rather Than Older Age, Are Strongly Associated With Higher Utilization of Healthcare in Colorectal Cancer Survivors.
Journal of the National Comprehensive Cancer Network 20(5), 468-478 (2022) [10.6004/jnccn.2021.7030]
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Journal Article
Impact of reducing excess body weight and physical inactivity on cancer incidence in Germany from 2020 to 2050-a simulation model.
European journal of cancer 160, 215-226 (2022) [10.1016/j.ejca.2021.10.026]
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Journal Article
Urinary estrogen metabolites and gastric cancer risk among postmenopausal women.
Cancer reports 5(7), e1574 (2022) [10.1002/cnr2.1574]
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Journal Article
Health and life insurance-related problems in very long-term cancer survivors in Germany: a population-based study.
Journal of cancer research and clinical oncology 148(1), 155-162 (2022) [10.1007/s00432-021-03825-x]
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Journal Article
Weakly supervised annotation-free cancer detection and prediction of genotype in routine histopathology.
The journal of pathology 256(1), 50-60 (2022) [10.1002/path.5800]
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Journal Article
Long-term effects of smoking on serum concentrations of oxidative stress biomarkers: Results of a large, population-based cohort study.
Environmental research 204(PT A), 111923 (2022) [10.1016/j.envres.2021.111923]
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Journal Article
Association of Sugar Intake with Inflammation- and Angiogenesis-Related Biomarkers in Newly Diagnosed Colorectal Cancer Patients.
Nutrition and cancer 74(5), 1636-1643 (2022) [10.1080/01635581.2021.1957133]
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Journal Article
Association of co-medication quality with chemotherapy-related adverse drug reactions and survival in older colorectal cancer patients
The journals of gerontology / A 77(5), 1009-1019 (2022) [10.1093/gerona/glab198]
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Journal Article
Alcohol Intake and Total Mortality in 142,960 Individuals from the MORGAM Project: a population-based study.
Addiction 117(2), 312-325 (2022) [10.1111/add.15593]
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