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Research

Publications of Pediatric Neurooncology

2018

Feng, W. (First author) ; Liu, H.-K. ; Kawauchi, D. (Last author)
CRISPR-engineered genome editing for the next generation neurological disease modeling.
Progress in neuro-psychopharmacology & biological psychiatry 81, 459 - 467 (2018) [10.1016/j.pnpbp.2017.05.019]2018 BibTeX | EndNote: XML, Text | RIS

Halliday, G. C. ; Junckerstorff, R. C. ; Bentel, J. M. ; Miles, A. ; Jones, D. ; Hovestadt, V. ; Capper, D. ; Endersby, R. ; Cole, C. H. ; van Hagen, T. ; Gottardo, N. G.
The case for DNA methylation based molecular profiling to improve diagnostic accuracy for central nervous system embryonal tumors (not otherwise specified) in adults.
Journal of clinical neuroscience 47, 163 - 167 (2018) [10.1016/j.jocn.2017.09.013]2018 BibTeX | EndNote: XML, Text | RIS

van Tilburg, C. M. (First author) ; Selt, F. ; Sahm, F. ; Bächli, H. ; Pfister, S. ; Witt, O. ; Milde, T. (Last author)
Response in a child with a BRAF V600E mutated desmoplastic infantile astrocytoma upon retreatment with vemurafenib.
Pediatric blood & cancer 65(3), e26893 - (2018) [10.1002/pbc.26893]2018 BibTeX | EndNote: XML, Text | RIS

Jones, D. (First author) ; Witt, O. ; Pfister, S. (Last author)
BRAF V600E Status Alone Is Not Sufficient as a Prognostic Biomarker in Pediatric Low-Grade Glioma.
Journal of clinical oncology 36(1), 96 - 96 (2018) [10.1200/JCO.2017.75.8987]2018 BibTeX | EndNote: XML, Text | RIS

Karremann, M. ; Gielen, G. H. ; Hoffmann, M. ; Wiese, M. ; Colditz, N. ; Warmuth-Metz, M. ; Bison, B. ; Claviez, A. ; van Vuurden, D. G. ; von Bueren, A. O. ; Gessi, M. ; Kühnle, I. ; Hans, V. H. ; Benesch, M. ; Sturm, D. ; Kortmann, R.-D. ; Waha, A. ; Pietsch, T. ; Kramm, C. M.
Diffuse high-grade gliomas with H3 K27M mutations carry a dismal prognosis independent of tumor location.
Neuro-Oncology 20(1), 123 - 131 (2018) [10.1093/neuonc/nox149]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Mack, S. C. ; Pajtler, K. (First author) ; Chavez, L. (First author) ; et al
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling.
Nature <London> 553(7686), 101 - 105 (2018) [10.1038/nature25169]2018 BibTeX | EndNote: XML, Text | RIS

Beier, D. ; Proescholdt, M. ; Reinert, C. ; Pietsch, T. ; Jones, D. ; Pfister, S. ; Hattingen, E. ; Seidel, C. ; Dirven, L. ; Luerding, R. ; Reijneveld, J. ; Warmuth-Metz, M. ; Bonsanto, M. ; Bremer, M. ; Combs, S. E. ; Rieken, S. ; Herrlinger, U. ; Kuntze, H. ; Mayer-Steinacker, R. ; Moskopp, D. ; Schneider, T. ; Beringer, A. ; Schlegel, U. ; Stummer, W. ; Welker, H. ; Weyerbrock, A. ; Paulsen, F. ; Rutkowski, S. ; Weller, M. ; Wick, W. ; Kortmann, R.-D. ; Bogdahn, U. ; Hau, P.
Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07).
Neuro-Oncology 20(3), 400 - 410 (2018) [10.1093/neuonc/nox155]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Hasselblatt, M. ; Kurniawan, A. D. ; Rozsnoki, S. ; Johann, P. ; Bens, S. ; Oyen, F. ; Schneppenheim, R. ; Siebert, R. ; Capper, D. ; Kool, M. ; Schul, C. ; Paulus, W.
Glial papillary tumour of the spinal cord with SMARCB1/INI1-loss and favourable long-term outcome.
Neuropathology & applied neurobiology 44(2), 229 - 232 (2018) [10.1111/nan.12395]2018 BibTeX | EndNote: XML, Text | RIS

Hübner, J.-M. (First author) ; Kool, M. ; Pfister, S. ; Pajtler, K. (Last author)
Epidemiology, molecular classification and WHO grading of ependymoma.
Journal of neurosurgical sciences 62(1), 46-50 (2018) [DOI:10.23736/S0390-5616.17.04152-2 ]2018 BibTeX | EndNote: XML, Text | RIS

Jones, D. (First author) ; Kieran, M. W. ; Bouffet, E. ; Alexandrescu, S. ; Bandopadhayay, P. ; Bornhorst, M. ; Ellison, D. ; Fangusaro, J. ; Fisher, M. J. ; Foreman, N. ; Fouladi, M. ; Hargrave, D. ; Hawkins, C. ; Jabado, N. ; Massimino, M. ; Mueller, S. ; Perilongo, G. ; Schouten van Meeteren, A. Y. N. ; Tabori, U. ; Warren, K. ; Waanders, A. J. ; Walker, D. ; Weiss, W. ; Witt, O. ; Wright, K. ; Zhu, Y. ; Bowers, D. C. ; Pfister, S. ; Packer, R. J.
Pediatric low-grade gliomas: next biologically driven steps.
Neuro-Oncology 20(2), 160 - 173 (2018) [10.1093/neuonc/nox141]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Vermeulen, J. F. ; Van Hecke, W. ; Adriaansen, E. J. M. ; Jansen, M. K. ; Bouma, R. G. ; Villacorta Hidalgo, J. ; Fisch, P. ; Broekhuizen, R. ; Spliet, W. G. M. ; Kool, M. ; Bovenschen, N.
Prognostic relevance of tumor-infiltrating lymphocytes and immune checkpoints in pediatric medulloblastoma.
OncoImmunology 7(3), e1398877 - (2018) [10.1080/2162402X.2017.1398877]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Kessler, T. (First author) ; Sahm, F. ; Sadik, A. ; Stichel, D. ; Hertenstein, A. ; Reifenberger, G. ; Zacher, A. ; Sabel, M. ; Tabatabai, G. ; Steinbach, J. ; Sure, U. ; Krex, D. ; Grosu, A.-L. ; Bewerunge-Hudler, M. ; Jones, D. ; Pfister, S. ; Weller, M. ; Opitz, C. ; Bendszus, M. ; von Deimling, A. ; Platten, M. ; Wick, W. (Last author)
Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation.
Neuro-Oncology 20(3), 367 - 379 (2018) [10.1093/neuonc/nox160]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Li, R. ; Cauchy, P. ; Ramamoorthy, S. ; Boller, S. ; Chavez, L. ; Grosschedl, R.
Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming.
Genes & development 32(2), 96 - 111 (2018) [10.1101/gad.309583.117]2018 BibTeX | EndNote: XML, Text | RIS

Infante, P. ; Faedda, R. ; Bernardi, F. ; Bufalieri, F. ; Lospinoso Severini, L. ; Alfonsi, R. ; Mazzà, D. ; Siler, M. ; Coni, S. ; Po, A. ; Petroni, M. ; Ferretti, E. ; Mori, M. ; De Smaele, E. ; Canettieri, G. ; Capalbo, C. ; Maroder, M. ; Screpanti, I. ; Kool, M. ; Pfister, S. ; Guardavaccaro, D. ; Gulino, A. ; Di Marcotullio, L.
Itch/?-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.
Nature Communications 9(1), 976 (2018) [10.1038/s41467-018-03339-0]2018 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Majewsky, M. ; Castel, D. ; Le Dret, L. ; Johann, P. ; Jones, D. ; Pfister, S. ; Haefeli, W. E. ; Burhenne, J.
Systematic identification of suspected anthelmintic benzimidazole metabolites using LC-MS/MS.
Journal of pharmaceutical and biomedical analysis 151, 151 - 158 (2018) [10.1016/j.jpba.2017.12.056]2018 BibTeX | EndNote: XML, Text | RIS

Capper, D. (First author) ; Jones, D. (First author) ; Sill, M. (First author) ; et al
DNA methylation-based classification of central nervous system tumours.
Nature <London> 555(7697), 469 - 474 (2018) [10.1038/nature26000]2018 BibTeX | EndNote: XML, Text | RIS

Filbin, M. G. ; Sturm, D. (Last author)
Gliomas in Children.
Seminars in neurology 38(1), 121 - 130 (2018) [10.1055/s-0038-1635106]2018 BibTeX | EndNote: XML, Text | RIS

Gerstner, E. R. ; Pajtler, K. (Last author)
Ependymoma.
Seminars in neurology 38(1), 104 - 111 (2018) [10.1055/s-0038-1636503]2018 BibTeX | EndNote: XML, Text | RIS

Gröbner, S. (First author) ; Worst, B. (First author) ; Weischenfeldt, J. ; et al
The landscape of genomic alterations across childhood cancers.
Nature <London> 555(7696), 321 - 327 (2018) [10.1038/nature25480]2018 BibTeX | EndNote: XML, Text | RIS

Gómez, S. ; Garrido-Garcia, A. ; Garcia-Gerique, L. ; Lemos, I. ; Suñol, M. ; de Torres, C. ; Kulis, M. ; Pérez-Jaume, S. ; Carcaboso, Á. M. ; Luu, B. ; Kieran, M. W. ; Jabado, N. ; Kozlenkov, A. ; Dracheva, S. ; Ramaswamy, V. ; Hovestadt, V. ; Johann, P. ; Jones, D. ; Pfister, S. ; Morales La Madrid, A. ; Cruz, O. ; Taylor, M. D. ; Martin-Subero, J.-I. ; Mora, J. ; Lavarino, C.
A Novel Method for Rapid Molecular Subgrouping of Medulloblastoma.
Clinical cancer research 24(6), 1355 - 1363 (2018) [10.1158/1078-0432.CCR-17-2243]2018 BibTeX | EndNote: XML, Text | RIS

Iorgulescu, J. B. ; Van Ziffle, J. ; Stevers, M. ; Grenert, J. P. ; Bastian, B. C. ; Chavez, L. ; Stichel, D. ; Buchhalter, I. ; Samuel, D. ; Nicolaides, T. ; Banerjee, A. ; Mueller, S. ; Gupta, N. ; Tihan, T. ; Bollen, A. W. ; Northcott, P. A. ; Kool, M. ; Pfister, S. ; Korshunov, A. ; Perry, A. ; Solomon, D. A.
Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation.
Acta neuropathologica 135(4), 635 - 638 (2018) [10.1007/s00401-018-1819-x]2018 BibTeX | EndNote: XML, Text | RIS

Merk, D. J. ; Ohli, J. ; Merk, N. D. ; Thatikonda, V. ; Morrissy, S. ; Schoof, M. ; Schmid, S. N. ; Harrison, L. ; Filser, S. ; Ahlfeld, J. ; Erkek, S. ; Raithatha, K. ; Andreska, T. ; Weißhaar, M. ; Launspach, M. ; Neumann, J. E. ; Shakarami, M. ; Plenker, D. ; Marra, M. A. ; Li, Y. ; Mungall, A. J. ; Moore, R. A. ; Ma, Y. ; Jones, S. J. M. ; Lutz, B. ; Ertl-Wagner, B. ; Rossi, A. ; Wagener, R. ; Siebert, R. ; Jung, A. ; Eberhart, C. G. ; Lach, B. ; Sendtner, M. ; Pfister, S. ; Taylor, M. D. ; Chavez, L. ; Kool, M. ; Schüller, U.
Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma.
Developmental cell 44(6), 709 - 724.e6 (2018) [10.1016/j.devcel.2018.02.012]2018 BibTeX | EndNote: XML, Text | RIS

Johann, P. (First author) ; Bens, S. ; Oyen, F. ; Wagener, R. ; Giannini, C. ; Perry, A. ; Raisanen, J. M. ; Reis, G. F. ; Nobusawa, S. ; Arita, K. ; Felsberg, J. ; Reifenberger, G. ; Agaimy, A. ; Buslei, R. ; Capper, D. ; Pfister, S. ; Schneppenheim, R. ; Siebert, R. ; Frühwald, M. C. ; Paulus, W. ; Kool, M. ; Hasselblatt, M.
Sellar Region Atypical Teratoid/Rhabdoid Tumors (ATRT) in Adults Display DNA Methylation Profiles of the ATRT-MYC Subgroup.
The American journal of surgical pathology 42(4), 506 - 511 (2018) [10.1097/PAS.0000000000001023]2018 BibTeX | EndNote: XML, Text | RIS

Rogers, S. ; Jones, D. ; Ireland, A. ; Gottardo, N. G. ; Endersby, R.
Unusual paediatric spinal myxopapillary ependymomas: Unique molecular entities or pathological variations on a theme?
Journal of clinical neuroscience 50, 144 - 148 (2018) [10.1016/j.jocn.2018.01.048]2018 BibTeX | EndNote: XML, Text | RIS

Rudà, R. ; Reifenberger, G. ; Frappaz, D. ; Pfister, S. ; Laprie, A. ; Santarius, T. ; Roth, P. ; Tonn, J. C. ; Soffietti, R. ; Weller, M. ; Moyal, E. C.
EANO guidelines for the diagnosis and treatment of ependymal tumors.
Neuro-Oncology 20(4), 445 - 456 (2018) [10.1093/neuonc/nox166]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Apps, J. R. ; Carreno, G. ; Gonzalez-Meljem, J. M. ; Haston, S. ; Guiho, R. ; Cooper, J. E. ; Manshaei, S. ; Jani, N. ; Hölsken, A. ; Pettorini, B. ; Beynon, R. J. ; Simpson, D. M. ; Fraser, H. C. ; Hong, Y. ; Hallang, S. ; Stone, T. J. ; Virasami, A. ; Donson, A. M. ; Jones, D. ; Aquilina, K. ; Spoudeas, H. ; Joshi, A. R. ; Grundy, R. ; Storer, L. C. D. ; Korbonits, M. ; Hilton, D. A. ; Tossell, K. ; Thavaraj, S. ; Ungless, M. A. ; Gil, J. ; Buslei, R. ; Hankinson, T. ; Hargrave, D. ; Goding, C. ; Andoniadou, C. L. ; Brogan, P. ; Jacques, T. S. ; Williams, H. J. ; Martinez-Barbera, J. P.
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Acta neuropathologica 135(5), 757 - 777 (2018) [10.1007/s00401-018-1830-2]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Benzel, J. (First author) ; Fendrich, V.
Chemoprevention and Treatment of Pancreatic Cancer: Update and Review of the Literature.
Digestion 97(4), 275 - 287 (2018) [10.1159/000485741]2018 BibTeX | EndNote: XML, Text | RIS

Rahimzadeh, V. ; Schickhardt, C. ; Knoppers, B. M. ; Sénécal, K. ; Vears, D. F. ; Fernandez, C. V. ; Pfister, S. ; Plon, S. ; Terry, S. ; Williams, J. ; Williams, M. S. ; Cornel, M. ; Friedman, J. M.
Key Implications of Data Sharing in Pediatric Genomics.
JAMA pediatrics 172(5), 476-481 (2018) [10.1001/jamapediatrics.2017.5500]2018 BibTeX | EndNote: XML, Text | RIS

Mackay, A. ; Burford, A. ; Molinari, V. ; Jones, D. ; Izquierdo, E. ; Brouwer-Visser, J. ; Giangaspero, F. ; Haberler, C. ; Pietsch, T. ; Jacques, T. S. ; Figarella-Branger, D. ; Rodriguez, D. ; Morgan, P. S. ; Raman, P. ; Waanders, A. J. ; Resnick, A. C. ; Massimino, M. ; Garrè, M. L. ; Smith, H. ; Capper, D. ; Pfister, S. ; Würdinger, T. ; Tam, R. ; Garcia, J. ; Thakur, M. D. ; Vassal, G. ; Grill, J. ; Jaspan, T. ; Varlet, P. ; Jones, C.
Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial.
Cancer cell 33(5), 829 - 842.e5 (2018) [10.1016/j.ccell.2018.04.004]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Kickingereder, P. ; Neuberger, U. ; Bonekamp, D. ; Piechotta, P. L. ; Götz, M. ; Wick, A. ; Sill, M. ; Kratz, A. ; Shinohara, R. T. ; Jones, D. ; Radbruch, A. ; Muschelli, J. ; Unterberg, A. ; Debus, J. ; Schlemmer, H.-P. ; Herold-Mende, C. ; Pfister, S. ; von Deimling, A. ; Wick, W. ; Capper, D. ; Maier-Hein, K. (Last author) ; Bendszus, M.
Radiomic subtyping improves disease stratification beyond key molecular, clinical, and standard imaging characteristics in patients with glioblastoma.
Neuro-Oncology 20(6), 848 - 857 (2018) [10.1093/neuonc/nox188]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Pfaff, E. (First author) ; Kessler, T. (First author) ; Balasubramanian, G. P. ; Berberich, A. ; Schrimpf, D. ; Wick, A. ; Debus, J. ; Unterberg, A. ; Bendszus, M. ; Herold-Mende, C. ; Capper, D. ; Schenkel, I. ; Eisenmenger, A. ; Dettmer, S. ; Brors, B. ; Platten, M. ; Pfister, S. ; von Deimling, A. ; Jones, D. (Last author) ; Wick, W. (Last author) ; Sahm, F. (Last author)
Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation-the NCT Neuro Master Match (N2M2) pilot study.
Neuro-Oncology 20(6), 826 - 837 (2018) [10.1093/neuonc/nox216]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Gozdecka, M. ; Meduri, E. ; Mazan, M. ; Tzelepis, K. ; Dudek, M. ; Knights, A. J. ; Pardo, M. ; Yu, L. ; Choudhary, J. S. ; Metzakopian, E. ; Iyer, V. ; Yun, H. ; Park, N. ; Varela, I. ; Bautista, R. ; Collord, G. ; Dovey, O. ; Garyfallos, D. A. ; De Braekeleer, E. ; Kondo, S. ; Cooper, J. ; Göttgens, B. ; Bullinger, L. ; Northcott, P. A. ; Adams, D. ; Vassiliou, G. S. ; Huntly, B. J. P.
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs.
Nature genetics 50(6), 883 - 894 (2018) [10.1038/s41588-018-0114-z]2018 BibTeX | EndNote: XML, Text | RIS

Robinson, G. W. ; Rudneva, V. A. ; Buchhalter, I. ; Billups, C. A. ; Waszak, S. M. ; Smith, K. S. ; Bowers, D. C. ; Bendel, A. ; Fisher, P. G. ; Partap, S. ; Crawford, J. R. ; Hassall, T. ; Indelicato, D. J. ; Boop, F. ; Klimo, P. ; Sabin, N. D. ; Patay, Z. ; Merchant, T. E. ; Stewart, C. F. ; Orr, B. A. ; Korbel, J. O. ; Jones, D. ; Sharma, T. ; Lichter, P. ; Kool, M. ; Korshunov, A. ; Pfister, S. ; Gilbertson, R. J. ; Sanders, R. P. ; Onar-Thomas, A. ; Ellison, D. W. ; Gajjar, A. ; Northcott, P. A.
Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial.
The lancet <London> / Oncology 19(6), 768 - 784 (2018) [10.1016/S1470-2045(18)30204-3]2018 BibTeX | EndNote: XML, Text | RIS

Waszak, S. M. ; Northcott, P. A. (First author) ; Buchhalter, I. ; et al
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.
The lancet <London> / Oncology 19(6), 785 - 798 (2018) [10.1016/S1470-2045(18)30242-0]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Rivero-Hinojosa, S. ; Lau, L. S. ; Stampar, M. ; Staal, J. ; Zhang, H. ; Gordish-Dressman, H. ; Northcott, P. A. ; Pfister, S. ; Taylor, M. D. ; Brown, K. J. ; Rood, B. R.
Proteomic analysis of Medulloblastoma reveals functional biology with translational potential.
Acta Neuropathologica Communications 6(1), 48 (2018) [10.1186/s40478-018-0548-7]2018 DBCoverage BibTeX | EndNote: XML, Text | RIS

Akgül, S. ; Li, Y. ; Zheng, S. ; Kool, M. ; Treisman, D. M. ; Li, C. ; Wang, Y. ; Gröbner, S. ; Ikenoue, T. ; Shen, Y. ; Camelo-Piragua, S. ; Tomasek, G. ; Stark, S. ; Guduguntla, V. ; Gusella, J. F. ; Guan, K.-L. ; Pfister, S. ; Verhaak, R. G. W. ; Zhu, Y.
Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma.
Cell reports 24(2), 463 - 478.e5 (2018) [10.1016/j.celrep.2018.06.050]2018 DBCoverage BibTeX | EndNote: XML, Text | RIS

Capper, D. (First author) ; Engel, N. W. ; Stichel, D. ; Lechner, M. ; Glöss, S. ; Schmid, S. ; Koelsche, C. ; Schrimpf, D. ; Niesen, J. ; Wefers, A. K. ; Jones, D. ; Sill, M. ; Weigert, O. ; Ligon, K. L. ; Olar, A. ; Koch, A. ; Forster, M. ; Moran, S. ; Tirado, O. M. ; Sáinz-Jaspeado, M. ; Mora, J. ; Esteller, M. ; Alonso, J. ; Del Muro, X. G. ; Paulus, W. ; Felsberg, J. ; Reifenberger, G. ; Glatzel, M. ; Frank, S. ; Monoranu, C. M. ; Lund, V. J. ; von Deimling, A. ; Pfister, S. ; Buslei, R. ; Ribbat-Idel, J. ; Perner, S. ; Gudziol, V. ; Meinhardt, M. ; Schüller, U.
DNA methylation-based reclassification of olfactory neuroblastoma.
Acta neuropathologica 136(2), 255 - 271 (2018) [10.1007/s00401-018-1854-7]2018 BibTeX | EndNote: XML, Text | RIS

Capper, D. (First author) ; Stichel, D. ; Sahm, F. ; Jones, D. ; Schrimpf, D. ; Sill, M. ; Schmid, S. ; Hovestadt, V. ; Reuss, D. E. ; Koelsche, C. ; Reinhardt, A. ; Wefers, A. K. ; Huang, K. ; Sievers, P. ; Ebrahimi, A. ; Schöler, A. ; Teichmann, D. ; Koch, A. ; Hänggi, D. ; Unterberg, A. ; Platten, M. ; Wick, W. ; Witt, O. ; Milde, T. ; Korshunov, A. ; Pfister, S. ; von Deimling, A. (Last author)
Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.
Acta neuropathologica 136(2), 181 - 210 (2018) [10.1007/s00401-018-1879-y]2018 BibTeX | EndNote: XML, Text | RIS

Cavalli, F. M. G. ; Hübner, J.-M. (First author) ; Sharma, T. (First author) ; et al
Heterogeneity within the PF-EPN-B ependymoma subgroup.
Acta neuropathologica 136(2), 227 - 237 (2018) [10.1007/s00401-018-1888-x]2018 BibTeX | EndNote: XML, Text | RIS

Deng, M. Y. (First author) ; Sill, M. ; Chiang, J. ; Schittenhelm, J. ; Ebinger, M. ; Schuhmann, M. U. ; Monoranu, C.-M. ; Milde, T. ; Wittmann, A. ; Hartmann, C. ; Sommer, C. ; Paulus, W. ; Gärtner, J. ; Brück, W. ; Rüdiger, T. ; Leipold, A. ; Jaunmuktane, Z. ; Brandner, S. ; Giangaspero, F. ; Nozza, P. ; Mora, J. ; Morales la Madrid, A. ; Cruz Martinez, O. ; Hansford, J. R. ; Pietsch, T. ; Tietze, A. ; Hernáiz-Driever, P. ; Stoler, I. ; Capper, D. ; Korshunov, A. ; Ellison, D. W. ; von Deimling, A. ; Pfister, S. ; Sahm, F. ; Jones, D. (Last author)
Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features.
Acta neuropathologica 136(2), 239 - 253 (2018) [10.1007/s00401-018-1865-4]2018 BibTeX | EndNote: XML, Text | RIS

Koelsche, C. (First author) ; Mynarek, M. ; Schrimpf, D. ; Bertero, L. ; Serrano, J. ; Sahm, F. ; Reuss, D. E. ; Hou, Y. ; Baumhoer, D. ; Vokuhl, C. ; Flucke, U. ; Petersen, I. ; Brück, W. ; Rutkowski, S. ; Zambrano, S. C. ; Garcia Leon, J. L. ; Diaz Coronado, R. Y. ; Gessler, M. ; Tirado, O. M. ; Mora, J. ; Alonso, J. ; Garcia Del Muro, X. ; Esteller, M. ; Sturm, D. ; Ecker, J. ; Milde, T. ; Pfister, S. ; Korshunov, A. ; Snuderl, M. ; Mechtersheimer, G. ; Schüller, U. ; Jones, D. (Last author) ; von Deimling, A. (Last author)
Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.
Acta neuropathologica 136(2), 327 - 337 (2018) [10.1007/s00401-018-1871-6]2018 BibTeX | EndNote: XML, Text | RIS

Korshunov, A. (First author) ; Sahm, F. ; Stichel, D. ; Schrimpf, D. ; Ryzhova, M. ; Zheludkova, O. ; Golanov, A. ; Lichter, P. ; Jones, D. ; von Deimling, A. ; Pfister, S. ; Kool, M. (Last author)
Molecular characterization of medulloblastomas with extensive nodularity (MBEN).
Acta neuropathologica 136(2), 303 - 313 (2018) [10.1007/s00401-018-1840-0]2018 BibTeX | EndNote: XML, Text | RIS

Pajtler, K. (First author) ; Pfister, S. (Last author)
A Mouse Ependymoma Model Provides Molecular Insights into Tumor Formation.
Cell reports 23(13), 3699 - 3700 (2018) [10.1016/j.celrep.2018.06.062]2018 DBCoverage BibTeX | EndNote: XML, Text | RIS

Pajtler, K. (First author) ; Wen, J. ; Sill, M. (First author) ; Lin, T. ; Orisme, W. ; Tang, B. ; Hübner, J.-M. ; Ramaswamy, V. ; Jia, S. ; Dalton, J. D. ; Haupfear, K. ; Rogers, H. A. ; Punchihewa, C. ; Lee, R. ; Easton, J. ; Wu, G. ; Ritzmann, T. A. ; Chapman, R. ; Chavez, L. ; Boop, F. A. ; Klimo, P. ; Sabin, N. D. ; Ogg, R. ; Mack, S. C. ; Freibaum, B. D. ; Kim, H. J. ; Witt, H. ; Jones, D. ; Vo, B. ; Gajjar, A. ; Pounds, S. ; Onar-Thomas, A. ; Roussel, M. F. ; Zhang, J. ; Taylor, J. P. ; Merchant, T. E. ; Grundy, R. ; Tatevossian, R. G. ; Taylor, M. D. ; Pfister, S. M. ; Korshunov, A. ; Kool, M. (Last author) ; Ellison, D. W.
Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.
Acta neuropathologica 136(2), 211 - 226 (2018) [10.1007/s00401-018-1877-0]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Reinhardt, A. (First author) ; Stichel, D. ; Schrimpf, D. ; et al
Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.
Acta neuropathologica 136(2), 273 - 291 (2018) [10.1007/s00401-018-1837-8]2018 BibTeX | EndNote: XML, Text | RIS

Sexton-Oates, A. ; Dodgshun, A. ; Hovestadt, V. ; Jones, D. ; Ashley, D. M. ; Sullivan, M. ; MacGregor, D. ; Saffery, R.
Methylation profiling of paediatric pilocytic astrocytoma reveals variants specifically associated with tumour location and predictive of recurrence.
Molecular oncology 12(8), 1219 - 1232 (2018) [10.1002/1878-0261.12062]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Shirahata, M. ; Ono, T. ; Stichel, D. (First author) ; Schrimpf, D. ; Reuss, D. E. ; Sahm, F. ; Koelsche, C. ; Wefers, A. ; Reinhardt, A. ; Huang, K. ; Sievers, P. ; Shimizu, H. ; Nanjo, H. ; Kobayashi, Y. ; Miyake, Y. ; Suzuki, T. ; Adachi, J.-I. ; Mishima, K. ; Sasaki, A. ; Nishikawa, R. ; Bewerunge-Hudler, M. ; Ryzhova, M. ; Absalyamova, O. ; Golanov, A. ; Sinn, P. ; Platten, M. ; Jungk, C. ; Winkler, F. ; Wick, A. ; Hänggi, D. ; Unterberg, A. ; Pfister, S. ; Jones, D. ; van den Bent, M. ; Hegi, M. ; French, P. ; Baumert, B. G. ; Stupp, R. ; Gorlia, T. ; Weller, M. ; Capper, D. ; Korshunov, A. ; Herold-Mende, C. ; Wick, W. ; Louis, D. N. ; von Deimling, A. (Last author)
Novel, improved grading system(s) for IDH-mutant astrocytic gliomas.
Acta neuropathologica 136(1), 153 - 166 (2018) [10.1007/s00401-018-1849-4]2018 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Stichel, D. ; Schrimpf, D. ; Sahm, F. ; Koelsche, C. ; Reuss, D. E. ; Wefers, A. K. ; Reinhardt, A. ; Huang, K. ; Ebrahimi, A. ; Hou, Y. ; Pajtler, K. ; Pfister, S. ; Hasselblatt, M. ; Stummer, W. ; Schick, U. ; Hartmann, C. ; Hagel, C. ; Staszewski, O. ; Reifenberger, G. ; Beschorner, R. ; Coras, R. ; Keyvani, K. ; Kohlhof, P. ; Diomedi-Camassei, F. ; Herold-Mende, C. ; Giangaspero, F. ; Rushing, E. ; Giannini, C. ; Korshunov, A. ; Jones, D. (Last author) ; von Deimling, A. (Last author)
FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.
Acta neuropathologica 136(2), 293 - 302 (2018) [10.1007/s00401-018-1882-3]2018 BibTeX | EndNote: XML, Text | RIS

Snuderl, M. ; Kannan, K. ; Pfaff, E. ; Wang, S. ; Stafford, J. M. ; Serrano, J. ; Heguy, A. ; Ray, K. ; Faustin, A. ; Aminova, O. ; Dolgalev, I. ; Stapleton, S. L. ; Zagzag, D. ; Chiriboga, L. ; Gardner, S. L. ; Wisoff, J. H. ; Golfinos, J. G. ; Capper, D. ; Hovestadt, V. ; Rosenblum, M. K. ; Placantonakis, D. G. ; LeBoeuf, S. E. ; Papagiannakopoulos, T. Y. ; Chavez, L. ; Ahsan, S. ; Eberhart, C. G. ; Pfister, S. ; Jones, D. ; Karajannis, M. A.
Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma.
Nature Communications 9(1), 2868 (2018) [10.1038/s41467-018-05029-3]2018 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Solomon, D. A. ; Korshunov, A. ; Sill, M. ; Jones, D. ; Kool, M. ; Pfister, S. ; Fan, X. ; Bannykh, S. ; Hu, J. ; Danielpour, M. ; Li, R. ; Johnston, J. ; Cham, E. ; Cooney, T. ; Sun, P. P. ; Oberheim Bush, N. A. ; McDermott, M. ; Van Ziffle, J. ; Onodera, C. ; Grenert, J. P. ; Bastian, B. C. ; Villanueva-Meyer, J. E. ; Pekmezci, M. ; Bollen, A. W. ; Perry, A.
Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile.
Acta neuropathologica 136(2), 339 - 343 (2018) [10.1007/s00401-018-1883-2]2018 BibTeX | EndNote: XML, Text | RIS

Wegert, J. ; Vokuhl, C. ; Collord, G. ; Del Castillo Velasco-Herrera, M. ; Farndon, S. J. ; Guzzo, C. ; Jorgensen, M. ; Anderson, J. ; Slater, O. ; Duncan, C. ; Bausenwein, S. ; Streitenberger, H. ; Ziegler, B. ; Furtwängler, R. ; Graf, N. ; Stratton, M. R. ; Campbell, P. J. ; Jones, D. ; Koelsche, C. ; Pfister, S. ; Mifsud, W. ; Sebire, N. ; Sparber-Sauer, M. ; Koscielniak, E. ; Rosenwald, A. ; Gessler, M. ; Behjati, S.
Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants.
Nature Communications 9(1), 2378 (2018) [10.1038/s41467-018-04650-6]2018 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Hoffman, L. M. ; Veldhuijzen van Zanten, S. E. M. ; Colditz, N. ; et al
Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.
Journal of clinical oncology 36(19), 1963 - 1972 (2018) [10.1200/JCO.2017.75.9308]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Bächli, H. ; Ecker, J. ; van Tilburg, C. M. ; Sturm, D. ; Selt, F. ; Sahm, F. ; Koelsche, C. ; Grund, K. B. ; Sutter, C. ; Pietsch, T. ; Witt, H. ; Herold-Mende, C. ; von Deimling, A. ; Jones, D. ; Pfister, S. ; Witt, O. ; Milde, T. (Last author)
Molecular Diagnostics in Pediatric Brain Tumors: Impact on Diagnosis and Clinical Decision-Making - A Selected Case Series.
Klinische Pädiatrie 230(6), 305-313 (2018) [10.1055/a-0637-9653]2018 BibTeX | EndNote: XML, Text | RIS

Koelsche, C. (First author) ; Hartmann, W. ; Schrimpf, D. ; Stichel, D. ; Jabar, S. ; Ranft, A. ; Reuss, D. E. ; Sahm, F. ; Jones, D. ; Bewerunge-Hudler, M. ; Trautmann, M. ; Klingebiel, T. ; Vokuhl, C. ; Gessler, M. ; Wardelmann, E. ; Petersen, I. ; Baumhoer, D. ; Flucke, U. ; Antonescu, C. ; Esteller, M. ; Fröhling, S. ; Kool, M. ; Pfister, S. ; Mechtersheimer, G. ; Dirksen, U. ; von Deimling, A. (Last author)
Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information.
Modern pathology 31(8), 1246 - 1256 (2018) [10.1038/s41379-018-0045-3]2018 BibTeX | EndNote: XML, Text | RIS

Stichel, D. (First author) ; Ebrahimi, A. (First author) ; Reuss, D. ; Schrimpf, D. ; Ono, T. ; Shirahata, M. ; Reifenberger, G. ; Weller, M. ; Hänggi, D. ; Wick, W. ; Herold-Mende, C. ; Westphal, M. ; Brandner, S. ; Pfister, S. ; Capper, D. ; Sahm, F. ; von Deimling, A. (Last author)
Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma.
Acta neuropathologica 136(5), 793-803 (2018) [10.1007/s00401-018-1905-0]2018 BibTeX | EndNote: XML, Text | RIS

Archer, T. C. ; Ehrenberger, T. ; Mundt, F. ; Gold, M. P. ; Krug, K. ; Mah, C. K. ; Mahoney, E. L. ; Daniel, C. J. ; LeNail, A. ; Ramamoorthy, D. ; Mertins, P. ; Mani, D. R. ; Zhang, H. ; Gillette, M. A. ; Clauser, K. ; Noble, M. ; Tang, L. C. ; Pierre-François, J. ; Silterra, J. ; Jensen, J. ; Tamayo, P. ; Korshunov, A. ; Pfister, S. ; Kool, M. ; Northcott, P. A. ; Sears, R. C. ; Lipton, J. O. ; Carr, S. A. ; Mesirov, J. P. ; Pomeroy, S. L. ; Fraenkel, E.
Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups.
Cancer cell 34(3), 396 - 410.e8 (2018) [10.1016/j.ccell.2018.08.004]2018 BibTeX | EndNote: XML, Text | RIS

Forget, A. ; Martignetti, L. ; Puget, S. ; Calzone, L. ; Brabetz, S. ; Picard, D. J. ; Montagud, A. ; Liva, S. ; Sta, A. ; Dingli, F. ; Arras, G. ; Rivera, J. ; Loew, D. ; Besnard, A. ; Lacombe, J. ; Pagès, M. ; Varlet, P. ; Dufour, C. ; Yu, H. ; Mercier, A. L. ; Indersie, E. ; Chivet, A. ; Leboucher, S. ; Sieber, L. ; Beccaria, K. ; Gombert, M. ; Meyer, F.-D. ; Qin, N. ; Bartl, J. ; Chavez, L. ; Okonechnikov, K. ; Sharma, T. ; Thatikonda, V. ; Bourdeaut, F. ; Pouponnot, C. ; Ramaswamy, V. ; Korshunov, A. ; Borkhardt, A. ; Reifenberger, G. ; Poullet, P. ; Taylor, M. D. ; Kool, M. ; Pfister, S. ; Kawauchi, D. ; Barillot, E. ; Remke, M. ; Ayrault, O.
Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.
Cancer cell 34(3), 379 - 395.e7 (2018) [10.1016/j.ccell.2018.08.002]2018 BibTeX | EndNote: XML, Text | RIS

Feng, W. (First author) ; Herbst, L. (First author) ; Lichter, P. ; Pfister, S. ; Liu, H.-K. ; Kawauchi, D. (Last author)
CRISPR-mediated Loss of Function Analysis in Cerebellar Granule Cells Using In Utero Electroporation-based Gene Transfer.
Journal of visualized experiments 9(136), 57311 (2018) [10.3791/57311]2018 BibTeX | EndNote: XML, Text | RIS

Dudvarski Stankovic, N. ; Bicker, F. ; Keller, S. ; Jones, D. ; Harter, P. ; Kienzle, A. ; Gillmann, C. ; Arnold, P. ; Golebiewska, A. ; Keunen, O. ; Giese, A. ; von Deimling, A. ; Bäuerle, T. ; Niclou, S. P. ; Mittelbronn, M. ; Ye, W. ; Pfister, S. ; Schmidt, M. H.
EGFL7 enhances surface expression of integrin ? 5 ? 1 to promote angiogenesis in malignant brain tumors
EMBO molecular medicine 10(9), e8420 (2018) [10.15252/emmm.201708420]2018 DBCoverage BibTeX | EndNote: XML, Text | RIS

Patel, A. K. ; Vipparthi, K. ; Thatikonda, V. ; Arun, I. ; Bhattacharjee, S. ; Sharan, R. ; Arun, P. ; Singh, S.
A subtype of cancer-associated fibroblasts with lower expression of alpha-smooth muscle actin suppresses stemness through BMP4 in oral carcinoma.
Oncogenesis 7(10), 78 (2018) [10.1038/s41389-018-0087-x]2018 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Appay, R. ; Fina, F. ; Macagno, N. ; Padovani, L. ; Colin, C. ; Barets, D. ; Ordioni, J. ; Scavarda, D. ; Giangaspero, F. ; Badiali, M. ; Korshunov, A. ; Pfister, S. ; Jones, D. ; Figarella-Branger, D.
Duplications of KIAA1549 and BRAF screening by Droplet Digital PCR from formalin-fixed paraffin-embedded DNA is an accurate alternative for KIAA1549-BRAF fusion detection in pilocytic astrocytomas.
Modern pathology 31(10), 1490 - 1501 (2018) [10.1038/s41379-018-0050-6]2018 BibTeX | EndNote: XML, Text | RIS

Wang, A. C. ; Jones, D. ; Abecassis, I. J. ; Cole, B. L. ; Leary, S. E. S. ; Lockwood, C. M. ; Chavez, L. ; Capper, D. ; Korshunov, A. ; Fallah, A. ; Wang, S. ; Ene, C. ; Olson, J. M. ; Geyer, J. R. ; Holland, E. C. ; Lee, A. ; Ellenbogen, R. G. ; Ojemann, J. G.
Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIG/DIA) Are Distinct Entities with Frequent BRAFV600 Mutations.
Molecular cancer research 16(10), 1491 - 1498 (2018) [10.1158/1541-7786.MCR-17-0507]2018 BibTeX | EndNote: XML, Text | RIS

Benzel, J. (First author) ; Fendrich, V.
Familial Pancreatic Cancer.
Oncology research and treatment 41(10), 611 - 618 (2018) [10.1159/000493473]2018 BibTeX | EndNote: XML, Text | RIS

Hwang, E. I. ; Kool, M. (First author) ; Burger, P. C. ; Capper, D. ; Chavez, L. ; Brabetz, S. ; Williams-Hughes, C. ; Billups, C. ; Heier, L. ; Jaju, A. ; Michalski, J. ; Li, Y. ; Leary, S. ; Zhou, T. ; von Deimling, A. ; Jones, D. ; Fouladi, M. ; Pollack, I. F. ; Gajjar, A. ; Packer, R. J. ; Pfister, S. ; Olson, J. M.
Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial.
Journal of clinical oncology 36(34), 3388 (2018) [10.1200/JCO.2017.76.4720]2018 BibTeX | EndNote: XML, Text | RIS

Sievers, P. (First author) ; Stichel, D. ; Hielscher, T. ; Schrimpf, D. ; Reinhardt, A. ; Wefers, A. K. ; Reuss, D. ; Jones, D. ; Bewerunge-Hudler, M. ; Hartmann, C. ; Baumgarten, P. ; Wirsching, H.-G. ; Winther-Kristensen, B. ; Brokinkel, B. ; Ketter, R. ; Idoate Gastearena, M. A. ; Lamszus, K. ; Seiz-Rosenhagen, M. ; Mawrin, C. ; Harter, P. ; Felsberg, J. ; Hänggi, D. ; Herold-Mende, C. ; Berghoff, A. S. ; Weller, M. ; Pfister, S. ; Wick, W. ; Reifenberger, G. ; Preusser, M. ; von Deimling, A. ; Sahm, F. (Last author)
Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p.1
Acta neuropathologica 136(6), 975-978 (2018) [10.1007/s00401-018-1924-x]2018 BibTeX | EndNote: XML, Text | RIS

Brabetz, S. (First author) ; Leary, S. E. S. ; Gröbner, S. ; Nakamoto, M. W. ; ?eker-Cin, H. ; Girard, E. J. ; Cole, B. ; Strand, A. D. ; Bloom, K. L. ; Hovestadt, V. ; Mack, N. ; Pakiam, F. ; Schwalm, B. ; Korshunov, A. ; Balasubramanian, G. P. ; Northcott, P. A. ; Pedro, K. D. ; Dey, J. ; Hansen, S. ; Ditzler, S. ; Lichter, P. ; Chavez, L. ; Jones, D. ; Koster, J. ; Pfister, S. ; Kool, M. ; Olson, J. M.
A biobank of patient-derived pediatric brain tumor models.
Nature medicine 24(11), 1752 - 1761 (2018) [10.1038/s41591-018-0207-3]2018 BibTeX | EndNote: XML, Text | RIS

Castel, D. ; Philippe, C. ; Kergrohen, T. ; Sill, M. ; Merlevede, J. ; Barret, E. ; Puget, S. ; Sainte-Rose, C. ; Kramm, C. M. ; Jones, C. ; Varlet, P. ; Pfister, S. ; Grill, J. ; Jones, D. ; Debily, M.-A.
Transcriptomic and epigenetic profiling of diffuse midline gliomas, H3 K27M-mutant discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location.
Acta Neuropathologica Communications 6(1), 117 (2018) [10.1186/s40478-018-0614-1]2018 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Korshunov, A. (First author) ; Chavez, L. ; Sharma, T. ; Ryzhova, M. ; Schrimpf, D. ; Stichel, D. ; Capper, D. ; Sturm, D. ; Kool, M. ; Habel, A. ; Kleinschmidt-DeMasters, B. K. ; Rosenblum, M. ; Absalyamova, O. ; Golanov, A. ; Lichter, P. ; Pfister, S. ; Jones, D. ; Perry, A. ; von Deimling, A. (Last author)
Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.
Brain pathology 28(5), 656 - 662 (2018) [10.1111/bpa.12566]2018 BibTeX | EndNote: XML, Text | RIS

Tejada Neyra, M. A. ; Neuberger, U. ; Reinhardt, A. ; Brugnara, G. ; Bonekamp, D. ; Sill, M. ; Wick, A. ; Jones, D. ; Radbruch, A. ; Unterberg, A. ; Debus, J. ; Heiland, S. ; Schlemmer, H.-P. ; Herold-Mende, C. ; Pfister, S. ; von Deimling, A. ; Wick, W. ; Capper, D. ; Bendszus, M. ; Kickingereder, P.
Voxel-wise radiogenomic mapping of tumor location with key molecular alterations in patients with glioma.
Neuro-Oncology 20(11), 1517 - 1524 (2018) [10.1093/neuonc/noy134]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Ratnaparkhe, M. (First author) ; Wong, J. K. L. ; Wei, P.-C. ; Hlevnjak, M. ; Kolb, T. ; Simovic, M. ; Haag, D. ; Paul, Y. ; Devens, F. ; Northcott, P. ; Jones, D. ; Kool, M. ; Jauch, A. ; Pastorczak, A. ; Mlynarski, W. ; Korshunov, A. ; Kumar, R. ; Downing, S. M. ; Pfister, S. ; Zapatka, M. ; McKinnon, P. J. ; Alt, F. W. ; Lichter, P. ; Ernst, A. (Last author)
Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors.
Nature Communications 9(1), 4760 (2018) [10.1038/s41467-018-06925-4]2018 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Ackermann, S. ; Cartolano, M. ; Hero, B. ; Welte, A. ; Kahlert, Y. ; Roderwieser, A. ; Bartenhagen, C. ; Walter, E. ; Gecht, J. ; Kerschke, L. ; Volland, R. ; Menon, R. ; Heuckmann, J. M. ; Gartlgruber, M. ; Hartlieb, S. ; Henrich, K.-O. ; Okonechnikov, K. ; Altmüller, J. ; Nürnberg, P. ; Lefever, S. ; de Wilde, B. ; Sand, F. ; Ikram, F. ; Rosswog, C. ; Fischer, J. ; Theissen, J. ; Hertwig, F. ; Singhi, A. D. ; Simon, T. ; Vogel, W. ; Perner, S. ; Krug, B. ; Schmidt, M. ; Rahmann, S. ; Achter, V. ; Lang, U. ; Vokuhl, C. ; Ortmann, M. ; Büttner, R. ; Eggert, A. ; Speleman, F. ; O'Sullivan, R. J. ; Thomas, R. K. ; Berthold, F. ; Vandesompele, J. ; Schramm, A. ; Westermann, F. (Last author) ; Schulte, J. (Last author) ; Peifer, M. ; Fischer, M.
A mechanistic classification of clinical phenotypes in neuroblastoma.
Science 362(6419), 1165 - 1170 (2018) [10.1126/science.aat6768]2018 BibTeX | EndNote: XML, Text | RIS

Okonechnikov, K. (First author) ; Mack, S. C. ; Kool, M. ; Pfister, S. ; Pajtler, K. (Last author)
Interrogating the enhancer landscape of intracranial ependymomas: perspectives for precision medicine
Expert review of precision medicine and drug development 3(3), 147 - 149 (2018) [10.1080/23808993.2018.1467210]2018 BibTeX | EndNote: XML, Text | RIS

Rutkowski, S. ; Modena, P. ; Williamson, D. ; Kerl, K. ; Nysom, K. ; Pizer, B. ; Bartels, U. ; Puget, S. ; Doz, F. ; Michalski, A. ; von Hoff, K. ; Chevignard, M. ; Avula, S. ; Murray, M. J. ; Schönberger, S. ; Czech, T. ; Schouten-van Meeteren, A. Y. N. ; Kordes, U. ; Kramm, C. M. ; van Vuurden, D. G. ; Hulleman, E. ; Janssens, G. O. ; Solanki, G. A. ; van Veelen, M. C. ; Thomale, U. ; Schuhmann, M. U. ; Jones, C. ; Giangaspero, F. ; Figarella-Branger, D. ; Pietsch, T. ; Clifford, S. C. ; Pfister, S. ; Van Gool, S. W.
Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group.
The lancet <London> / Oncology Oncology 19(8), e419 - e428 (2018) [10.1016/S1470-2045(18)30364-4]2018 BibTeX | EndNote: XML, Text | RIS

Zuckermann, M. (First author) ; Hlevnjak, M. ; Yazdanparast, H. ; Zapatka, M. ; Jones, D. ; Lichter, P. ; Gronych, J. (Last author)
A novel cloning strategy for one-step assembly of multiplex CRISPR vectors.
Scientific reports 8(1), 17499 (2018) [10.1038/s41598-018-35727-3]2018 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Wirsching, H.-G. ; Tabatabai, G. ; Roelcke, U. ; Hottinger, A. F. ; Jörger, F. ; Schmid, A. ; Plasswilm, L. ; Schrimpf, D. ; Mancao, C. ; Capper, D. ; Conen, K. ; Hundsberger, T. ; Caparrotti, F. ; von Moos, R. ; Riklin, C. ; Felsberg, J. ; Roth, P. ; Jones, D. ; Pfister, S. ; Rushing, E. J. ; Abrey, L. ; Reifenberger, G. ; Held, L. ; von Deimling, A. ; Ochsenbein, A. ; Weller, M.
Bevacizumab plus hypofractionated radiotherapy versus radiotherapy alone in elderly patients with glioblastoma: the randomized, open-label, phase II ARTE trial.
Annals of oncology 29(6), 1423 - 1430 (2018) [10.1093/annonc/mdy120]2018 BibTeX | EndNote: XML, Text | RIS

Witt, H. (First author) ; Gramatzki, D. ; Hentschel, B. ; Pajtler, K. ; Felsberg, J. ; Schackert, G. ; Löffler, M. ; Capper, D. ; Sahm, F. ; Sill, M. ; von Deimling, A. ; Kool, M. ; Herrlinger, U. ; Westphal, M. ; Pietsch, T. ; Reifenberger, G. ; Pfister, S. ; Tonn, J. C. ; Weller, M. ; Network, G. G. (Collaboration Author)
DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment.
Neuro-Oncology 20(12), 1616 - 1624 (2018) [10.1093/neuonc/noy118]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Nowak, J. ; Nemes, K. ; Hohm, A. ; Vandergrift, L. A. ; Hasselblatt, M. ; Johann, P. ; Kool, M. ; Frühwald, M. C. ; Warmuth-Metz, M.
Magnetic resonance imaging surrogates of molecular subgroups in atypical teratoid/rhabdoid tumor.
Neuro-Oncology 20(12), 1672 - 1679 (2018) [10.1093/neuonc/noy111]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Rogers, H. A. ; Chapman, R. ; Kings, H. ; Allard, J. ; Barron-Hastings, J. ; Pajtler, K. W. ; Sill, M. ; Pfister, S. ; Grundy, R. G.
Limitations of current in vitro models for testing the clinical potential of epigenetic inhibitors for treatment of pediatric ependymoma.
OncoTarget 9(92), 36530-36541 (2018) [10.18632/oncotarget.26370]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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