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Publications of E041 in 2021

Master Thesis Baltazar, F.DKFZ*
FLASH optimization for multi-beam proton therapy
Masterarbeit, IST, University of Lisbon, 2021 BibTeX | EndNote: XML, Text | RIS

Bachelor Thesis Behr, C.DKFZ*
Detectability of radiation induced H2O2 with lowconcentrated fluorophores NucPE1 and PY1-ME
Bachelorarbeit, Universität Heidelberg, 2021 BibTeX | EndNote: XML, Text | RIS

Master Thesis Brieger, E.DKFZ*
Characterisation and comparison ofsmall extracellular vesicles after irradiationwith X-rays versus Carbon ions
Masterarbeit, Universität Heidelberg, 2021 BibTeX | EndNote: XML, Text | RIS

Bachelor Thesis Da Silva Azevedo, J.DKFZ*
Interconnection between cancer derived small extracellular vesicles and lipid droplets
Bachelorarbeit, University of Applied Sciences Mannheim, 2021 BibTeX | EndNote: XML, Text | RIS

Master Thesis Espinha, C.DKFZ*
A Computational Model for Radiotherapy Studieswith Proton and Carbon ion Mini-Beams
Masterarbeit, IST, University of Lisbon, 2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Freitas, H. (First author)DKFZ* ; Magalhaes Martins, P. J. (First author)DKFZ* ; Tessonnier, T. ; Ackermann, B. ; Brons, S. ; Seco, J. (Last author)DKFZ*
Dataset for predicting single-spot proton ranges in proton therapy of prostate cancer.
Scientific data 8(1), 252 (2021) [10.1038/s41597-021-01028-0]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Conference Presentation (Invited) Genard, G.DKFZ* ; Pagliari, F.DKFZ* ; Seco, J. (Corresponding author)DKFZ*
Carbon-ion therapy for immune activation in solid cancer: focus on small extracellular vesicles
2021The 5th Edition of the International Conference on Immunotherapy Radiotherapy Combinations, ParisParis, France, 14 Sep 2021 - 17 Sep 20212021-09-142021-09-17 BibTeX | EndNote: XML, Text | RIS

Dissertation / PhD Thesis Hanley, R.DKFZ*
Studying radiation generated DNA damage and how it is affected by oxygen and cellular metabolism
Dissertation, Universität Heidelberg, 2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Harris, T. (First author)DKFZ* ; Seco, J.DKFZ* ; Ferguson, D. ; Jacobson, M. ; Myronakis, M. ; Lozano, I. V. ; Lehmann, M. ; Huber, P. ; Fueglistaller, R. ; Morf, D. ; Mamon, H. J. ; Mancias, J. D. ; Martin, N. E. ; Berbeco, R. I.
Beam's-Eye-View Imaging of Liver SBRT With a Novel Multi-Layer Imager.
International journal of radiation oncology, biology, physics 111(3S), S47 (2021) [10.1016/j.ijrobp.2021.07.127]2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Harris, T. C. (First author)DKFZ* ; Seco, J.DKFZ* ; Ferguson, D. ; Jacobson, M. ; Myronakis, M. ; Lozano, I. V. ; Lehmann, M. ; Huber, P. ; Fueglistaller, R. ; Morf, D. ; Mamon, H. J. ; Mancias, J. D. ; Martin, N. E. ; Berbeco, R. I.
Improvements in beam's eye view fiducial tracking using a novel multilayer imager.
Physics in medicine and biology 66(15), 155007 (2021) [10.1088/1361-6560/ac1246]2021 BibTeX | EndNote: XML, Text | RIS

Dissertation / PhD Thesis Harris, T.DKFZ*
A Novel Megavoltage Multilayer Imager Improves Clinical Beam?s-Eye-View Performance
Dissertation, Universität Heidelberg, 2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Jansen, J. (First author)DKFZ* ; Knoll, J.DKFZ* ; Beyreuther, E. ; Pawelke, J. ; Skuza, R.DKFZ* ; Hanley, R.DKFZ* ; Brons, S. ; Pagliari, F.DKFZ* ; Seco, J. (Last author)DKFZ*
Does FLASH deplete Oxygen? Experimental Evaluation for Photons, Protons and Carbon Ions.
Medical physics 48(7), 3982-3990 (2021) [10.1002/mp.14917]2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Jansen, J. (First author)DKFZ* ; Vieten, P.DKFZ* ; Pagliari, F.DKFZ* ; Hanley, R.DKFZ* ; Marafioti, M. G. ; Tirinato, L.DKFZ* ; Seco, J. (Last author)DKFZ*
A Novel Analysis Method for Evaluating the Interplay of Oxygen and Ionizing Radiation at the Gene Level
Frontiers in genetics 12, 597635 (2021) [10.3389/fgene.2021.597635]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Dissertation / PhD Thesis Jansen, J.DKFZ*
Oxygen Effects in (FLASH-) Radiotherapy on a Radiochemical and Genetic Level
Dissertation, Universität Heidelberg, 2021 BibTeX | EndNote: XML, Text | RIS

Conference Presentation (Invited) Jansen, J.DKFZ* ; Knoll, J.DKFZ* ; Pagliari, F.DKFZ* ; Seco, J. (Corresponding author)DKFZ*
Implementation of an online oxygen meter for studying oxygen removal during FLASH irradiation
2021PTCOG 59, TaipeiTaipei, Taiwan, 4 Jun 2021 - 7 Jun 20212021-06-042021-06-07 BibTeX | EndNote: XML, Text | RIS

Conference Presentation (Invited) Karle, C.DKFZ* ; Seco, J. (Corresponding author)DKFZ*
Investigating water radiolysis during proton mini and micro beam irradiation with TOPAS-nBio
2021PTCOG 59, TaipeiTaipei, Taiwan, 4 Jun 2021 - 7 Jun 20212021-06-042021-06-07 BibTeX | EndNote: XML, Text | RIS

Conference Presentation (Invited) Knoll, J.DKFZ* ; Jansen, J.DKFZ* ; Seco, J. (Corresponding author)DKFZ*
MODULATING THE FLASH EFFECT ON A CELLULAR LEVEL FOR VARIABLE OXYGEN LEVELS
2021FRPT 2021 - FLASH RADIOTHERAPY AND PARTICLE THERAPY CONFERENCE, ViennaVienna, Austria, 1 Dec 2021 - 4 Dec 20212021-12-012021-12-04 BibTeX | EndNote: XML, Text | RIS

Journal Article Limongi, T. ; Brigo, L. ; Tirinato, L.DKFZ* ; Pagliari, F.DKFZ* ; Gandin, A. ; Contessotto, P. ; Giugni, A. ; Brusatin, G.
Three-dimensionally two-photon lithography realized vascular grafts.
Biomedical materials 16(3), 035013 (2021) [10.1088/1748-605X/abca4b]2021 BibTeX | EndNote: XML, Text | RIS

Contribution to a book Magalhaes Martins, P. J. (First author)DKFZ* ; Dal Bello, R.DKFZ* ; Seco, J. (Last author)DKFZ*
Prompt Gamma Detection forProton Range Verification
2021Radiation Therapy Dosimetry Boca Raton : CRC Press : 1st, 427-439 (2021)2021 Fulltext BibTeX | EndNote: XML, Text | RIS

Journal Article Magalhaes Martins, P. J. (First author)DKFZ* ; Freitas, H.DKFZ* ; Tessonnier, T. ; Ackermann, B. ; Brons, S. ; Seco, J. (Last author)DKFZ*
Towards real-time PGS range monitoring in proton therapy of prostate cancer.
Scientific reports 11(1), 15331 (2021) [10.1038/s41598-021-93612-y]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Contribution to a book Martins, P. ; Bello, R. D. ; Seco, J. (Corresponding author)DKFZ*
Prompt Gamma Detection for Proton Range Verification
2021Radiation Therapy Dosimetry: A Practical Handbook Boca Raton : CRC Press 427-442 (2021)2021 BibTeX | EndNote: XML, Text | RIS

Bachelor Thesis Milewski, K.DKFZ*
The damage response of human cancercells to irradiation under the variation ofthe dose rate and oxygen level
Bachelorarbeit, Universität Heidelberg, 2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Niebuhr, N. I. (First author)DKFZ* ; Splinter, M.DKFZ* ; Bostel, T.DKFZ* ; Seco, J.DKFZ* ; Hentschke, C. M. ; Floca, R. O.DKFZ* ; Hörner-Rieber, J.DKFZ* ; Alber, M. ; Huber, P.DKFZ* ; Nicolay, N. H.DKFZ* ; Pfaffenberger, A. (Last author)DKFZ*
Biologically consistent dose accumulation using daily patient imaging.
Radiation oncology 16(1), 65 (2021) [10.1186/s13014-021-01789-3]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Nistico, C. (First author)DKFZ* ; Pagliari, F.DKFZ* ; Chiarella, E. ; Fernandes Guerreiro, J. F.DKFZ* ; Marafioti, M. G.DKFZ* ; Aversa, I.DKFZ* ; Genard, G.DKFZ* ; Hanley, R.DKFZ* ; Garcia-Calderón, D.DKFZ* ; Bond, H. M. ; Mesuraca, M. ; Tirinato, L.DKFZ* ; Spadea, M. F. ; Seco, J. (Last author)DKFZ*
Lipid Droplet Biosynthesis Impairment through DGAT2 Inhibition Sensitizes MCF7 Breast Cancer Cells to Radiation
International journal of molecular sciences 22(18), 10102 (2021) [10.3390/ijms221810102]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Master Thesis Ochoa Parra, P.
End-to-end range prediction forheavier ion radiation therapy basedon Monte Carlo simulations
Masterarbeit, Universidad Nacional de Colombia, 2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Pettersen, H. E. S. ; Volz, L.DKFZ* ; Sølie, J. R. ; Alme, J. ; Barnaföldi, G. G. ; Barthel, R. ; van den Brink, A. ; Borshchov, V. ; Chaar, M. ; Eikeland, V. N. ; Genov, G. ; Grøttvik, O. S. ; Helstrup, H. ; Keidel, R. ; Kobdaj, C. ; van der Kolk, N. ; Mehendale, S. ; Meric, I. ; Odland, O. H. ; Papp, G. ; Peitzmann, T. ; Piersimoni, P. ; Protsenko, M. ; Rehman, A. U. ; Richter, M. ; Samnøy, A. T. ; Seco, J.DKFZ* ; Shafiee, H. ; Songmoolnak, A. ; Tambave, G. ; Tymchuk, I. ; Ullaland, K. ; Varga-Kofarago, M. ; Wagner, B. ; Xiao, R. ; Yang, S. ; Yokoyama, H. ; Roehrich, D.
Helium radiography with a digital tracking calorimeter-a Monte Carlo study for secondary track rejection.
Physics in medicine and biology 66(3), 035004 (2021) [10.1088/1361-6560/abca03]2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Pettersen, H. E. S. ; Aehle, M. ; Alme, J. ; Barnaföldi, G. G. ; Borshchov, V. ; van den Brink, A. ; Chaar, M. ; Eikeland, V. ; Feofilov, G. ; Garth, C. ; Gauger, N. R. ; Genov, G. ; Grøttvik, O. ; Helstrup, H. ; Igolkin, S. ; Keidel, R. ; Kobdaj, C. ; Kortus, T. ; Leonhardt, V. ; Mehendale, S. ; Mulawade, R. N. ; Odland, O. H. ; Papp, G. ; Peitzmann, T. ; Piersimoni, P. ; Protsenko, M. ; Rehman, A. U. ; Richter, M. ; Santana, J. ; Schilling, A. ; Seco, J.DKFZ* ; Songmoolnak, A. ; Sølie, J. R. ; Tambave, G. ; Tymchuk, I. ; Ullaland, K. ; Varga-Kofarago, M. ; Volz, L. ; Wagner, B. ; Wendzel, S. ; Wiebel, A. ; Xiao, R. ; Yang, S. ; Yokoyama, H. ; Zillien, S. ; Röhrich, D.
Investigating particle track topology for range telescopes in particle radiography using convolutional neural networks.
Acta oncologica 60(11), 1413-1418 (2021) [10.1080/0284186X.2021.1949037]2021 BibTeX | EndNote: XML, Text | RIS

Lecture (Invited) Seco, J. (Corresponding author)DKFZ*
Proton Therapy Lecture
2021Lecture at Teaching Course on Innovation in Radiation Therapy (), BibTeX | EndNote: XML, Text | RIS

Lecture (Outreach) Seco, J. (Corresponding author)DKFZ*
Particle Therapy Masterclass: From particle physics to radiation dose
2021Lecture at (), BibTeX | EndNote: XML, Text | RIS

Talk (non-conference) (Invited) Seco, J. (Corresponding author)DKFZ*
Think Like a Proton ?Be Positive?
2021EFOMP-ECMP 2020 Meeting, IrelandIreland, BibTeX | EndNote: XML, Text | RIS

Talk (non-conference) (Invited) Seco, J. (Corresponding author)DKFZ*
FLASH Radiation
2021Invited Talk by Department of Radiation Oncology, Washington University School of Medicine USA, USAUSA, BibTeX | EndNote: XML, Text | RIS

Lecture (Outreach) Seco, J. (Corresponding author)DKFZ*
Cancer Radiotherapy Introduction
2021Lecture at Heavy Ion Therapy Masterclass organized by CERN, Switzerland (Switzerland), BibTeX | EndNote: XML, Text | RIS

Lecture (Outreach) Seco, J. (Corresponding author)DKFZ*
Imaging in Radiotherapy andParticle Therapy
2021Lecture at Heavy Ion Therapy Masterclass organized by CERN, Switzerland (Switzerland), BibTeX | EndNote: XML, Text | RIS

Talk (non-conference) (Invited) Seco, J. (Corresponding author)DKFZ*
Radiotherapy requirements for a next generation ion therapy accelerator
2021NIMMS - Next Ion Medical Machine Study - CERN, Switzerland, SwitzerlandSwitzerland, BibTeX | EndNote: XML, Text | RIS

Talk (non-conference) (Invited) Seco, J. (Corresponding author)DKFZ*
Oxygen Consumption in FLASH Radiation
2021Invited Lecture University of Dartmouth, USA, USAUSA, BibTeX | EndNote: XML, Text | RIS

Talk (non-conference) (Invited) Seco, J. (Corresponding author)DKFZ*
?To FLASH or Not to FLASH?
2021Invited Lecture by Mayo Clinic, Rochester USA, USAUSA, BibTeX | EndNote: XML, Text | RIS

Lecture (Invited) Seco, J. (Corresponding author)DKFZ*
Computational_Methods_for_Radiochemistry
2021Lecture at Summer School: Applied computational methods in RT (), BibTeX | EndNote: XML, Text | RIS

Lecture (Invited) Seco, J. (Corresponding author)DKFZ*
Monte Carlo Application to Photon Beams
2021Lecture at 3rd Virtual Summer School - DKFZ (Germany), BibTeX | EndNote: XML, Text | RIS

Lecture (Plenary/Keynote) Seco, J. (Corresponding author)DKFZ*
To FLASH or Not to FLASH???
2021Lecture at UT Austin - Portugal Annual Meeting (), BibTeX | EndNote: XML, Text | RIS

Conference Presentation (Invited) Seco, J. (Corresponding author)DKFZ*
Oxygen Effect in FLASH RT
2021FRPT 2021 - FLASH RADIOTHERAPY AND PARTICLE THERAPY CONFERENCE, ViennaVienna, Austria, 1 Dec 2021 - 4 Dec 20212021-12-012021-12-04 BibTeX | EndNote: XML, Text | RIS

Lecture (Invited) Seco, J. (Corresponding author)DKFZ*
Proton Therapy research: what are the main future challenges?
2021Lecture at UT Austin Portugal Program - Short-Term Advanced Training in Proton Therapy (), BibTeX | EndNote: XML, Text | RIS

Lecture (Outreach) Seco, J. (Corresponding author)DKFZ*
Proton Therapy: An Overview and Research Directions
2021Lecture at LIP Mini Mini-School on Charged Particle Therapy Applications (Portugal), BibTeX | EndNote: XML, Text | RIS

Book Seco, J. (Editor)DKFZ* ; Verhaegen, F. (Editor)
Monte Carlo Techniques in Radiation Therapy: Applications to Dosimetry, Imaging, and Preclinical Radiotherapy
Boca Raton : CRC Press all (2021)2021 BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Spadea, M. F. ; Maspero, M. ; Zaffino, P. ; Seco, J. (Last author)DKFZ*
Deep learning-based synthetic-CT generation in radiotherapy and PET: a review.
Medical physics 48(11), 6537-6566 (2021) [10.1002/mp.15150]2021 BibTeX | EndNote: XML, Text | RIS

Abstract Thummerer, A. ; Zaffino, P. ; Oria, C. S. ; Meijers, A. ; Marmitt, G. G. ; Seco, J.DKFZ* ; Langendijk, J. ; Knopf, A. ; Spadea, M. ; Both, S.
Neural network based synthetic CTs for adaptive proton therapy of lung cancer
2021ESTRO Annual Meeting, Meeting location, BibTeX | EndNote: XML, Text | RIS

Journal Article Thummerer, A. ; Oria, C. S. ; Zaffino, P. ; Meijers, A. ; Marmitt, G. G. ; Wijsman, R. ; Seco, J.DKFZ* ; Langendijk, J. A. ; Knopf, A.-C. ; Spadea, M. F. ; Both, S.
Clinical suitability of deep learning based synthetic CTs for adaptive proton therapy of lung cancer.
Medical physics 48(12), 7673-7684 (2021) [10.1002/mp.15333]2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Tirinato, L. (First author)DKFZ* ; Marafioti, M. G. (First author)DKFZ* ; Pagliari, F. (First author)DKFZ* ; Jansen, J.DKFZ* ; Aversa, I.DKFZ* ; Hanley, R.DKFZ* ; Nisticò, C.DKFZ* ; Garcia-Calderón, D.DKFZ* ; Genard, G.DKFZ* ; Guerreiro, J. F. ; Costanzo, F. S. ; Seco, J. (Last author)DKFZ*
Lipid droplets and ferritin heavy chain: a devilish liaison in human cancer cell radioresistance.
eLife 10, e72943 (2021) [10.7554/eLife.72943]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Book Verhaegen, F. ; Seco, J. (Corresponding author)DKFZ*
Monte Carlo Techniques in Radiation TherapyIntroduction, Source Modelling, and Patient Dose Calculations
Boca Raton : CRC Press all (2021)2021 BibTeX | EndNote: XML, Text | RIS

Abstract Volz, L.DKFZ* ; Vichtl, T. ; Collins-Fekete, C.-A. ; Seco, J. (Corresponding author)DKFZ*
Towards a clinical helium ion imaging system
2021ESTRO Annual Meeting, Meeting location, BibTeX | EndNote: XML, Text | RIS

Conference Presentation (Invited) Volz, L.DKFZ* ; schulte, r. ; Seco, J. (Corresponding author)DKFZ*
Status update on the PTCOG-funded project ?Proof of Concept Evaluation of Helium imaging for range uncertainty reduction in particle therapy?
2021PTCOG 59, TaipeiTaipei, Taiwan, 4 Jun 2021 - 7 Jun 20212021-06-042021-06-07 BibTeX | EndNote: XML, Text | RIS

Award Volz, L. (Corresponding author)DKFZ*
Heidelberger Wilhelm-und-Else-Heraeus-Dissertations preis 2021
Wilhelm und Else Heraeus Foundation (2021)2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Volz, L. (First author)DKFZ* ; Collins-Fekete, C.-A. ; Bär, E. ; Brons, S. ; Graeff, C. ; Johnson, R. P. ; Runz, A.DKFZ* ; Sarosiek, C. ; Schulte, R. W. ; Seco, J. (Last author)DKFZ*
The accuracy of helium ion CT based particle therapy range prediction: an experimental study comparing different particle and x-ray CT modalities
Physics in medicine and biology 66(23), 235010 (2021) [10.1088/1361-6560/ac33ec]2021 BibTeX | EndNote: XML, Text | RIS

Bachelor Thesis Wüllner, A.DKFZ*
Toxicity studies on lung and pancreatic cancer celllines: An approach towards FLASH mechanisms
Bachelorarbeit, Universität Heidelberg, 2021 BibTeX | EndNote: XML, Text | RIS