Macromolecular polymers as a novel platform for the tumor directed delivery of drugs targeting molecular processes of apoptosis and radiation
Number of publications: 10
Israeli Partner: S. Lavi, Tel Aviv University
German Partner: P. Peschke (div. P. Huber), DKFZ
Publications
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Kiessling, F., Heilmann, M., Lammers, T., Ulbrich, K., Subr, V., Peschke, P., Waengler, B., Mier, W., Schrenk, H. H., Bock, M., Schad, L., Semmler, W.
Synthesis and characterization of HE-24.8: a polymeric contrast agent for magnetic resonance angiography 17 (1), Bioconjug Chem, 42-51, 2006 |
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Lammers, T., Kuhnlein, R., Kissel, M., Subr, V., Etrych, T., Pola, R., Pechar, M., Ulbrich, K., Storm, G., Huber, P., Peschke, P.
Effect of physicochemical modification on the biodistribution and tumor accumulation of HPMA copolymers 110 (1), J Control Release, 103-18, 2005 |
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Lammers, T., Lavi, S.
Role of type 2C protein phosphatases in growth regulation and in cellular stress signaling 42 (6), Crit Rev Biochem Mol Biol, 437-61, 2007 |
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Lammers, T., Peschke, P., Ehemann, V., Debus, J., Slobodin, B., Lavi, S., Huber, P.
Role of PP2Calpha in cell growth, in radio- and chemosensitivity, and in tumorigenicity 6, Mol Cancer, 65, 2007 |
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Lammers, T., Peschke, P., Kuhnlein, R., Subr, V., Ulbrich, K., Huber, P., Hennink, W., Storm, G.
Effect of intratumoral injection on the biodistribution and the therapeutic potential of HPMA copolymer-based drug delivery systems 8 (10), Neoplasia, 788-95, 2006 |
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Lammers, T., Subr, V., Peschke, P., Kuhnlein, R., Hennink, W. E., Ulbrich, K., Kiessling, F., Heilmann, M., Debus, J., Huber, P. E., Storm, G.
Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy 99 (6), Br J Cancer, 900-10, 2008 |
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Lammers, T., Subr, V., Ulbrich, K., Peschke, P., Huber, P. E., Hennink, W. E., Storm, G.
Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers 30 (20), Biomaterials, 3466-75, 2009 |
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Lammers, T., Subr, V., Ulbrich, K., Peschke, P., Huber, P. E., Hennink, W. E., Storm, G., Kiessling, F.
HPMA-based polymer therapeutics improve the efficacy of surgery, of radiotherapy and of chemotherapy combinations 5 (10), Nanomedicine (Lond), 1501-23, 2010 |
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Lammers, T., Ulbrich, K.
HPMA copolymers: 30 years of advances 62 (2), Adv Drug Deliv Rev, 119-21, 2010 |
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Shohat, M., Ben-Meir, D., Lavi, S.
Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells 7 (2), PLoS One, e32438, 2012 |