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Allard, P. ; Alhaj, N. ; Lobitz, S. ; Cario, H. ; Jarisch, A. ; Grosse, R. ; Oevermann, L. ; Hakimeh, D. ; Tagliaferri, L. ; Kohne, E. ; Kopp-Schneider, A. ; Kulozik, A. E. ; Kunz, J. B. Genetic modifiers of fetal hemoglobin affect the course of sickle cell disease in patients treated with hydroxyurea.
Haematologica 107 (7 ), 1577-1588 (2021 ) [10.3324/haematol.2021.278952 ] 2021
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Edelmann, D. (First author) ; Terzer, T. ; Richards, D. A Basic Treatment of the Distance Covariance
Sankhya? / B 83 (S1 ), 12 - 25 (2021 ) [10.1007/s13571-021-00248-z ] 2021
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Manoochehri, M. (First author) ; Hielscher, T. ; Borhani, N. ; Gerhäuser, C. ; Fletcher, O. ; Swerdlow, A. J. ; Ko, Y.-D. ; Brauch, H. ; Brüning, T. ; Hamann, U. (Last author) Epigenetic quantification of circulating immune cells in peripheral blood of triple-negative breast cancer patients
Clinical epigenetics 13 (1 ), 207 (2021 ) [10.1186/s13148-021-01196-1 ] 2021
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Heilig, C. (First author) ; Horak, P. ; Kreutzfeldt, S. ; Teleanu, V. ; Mock, A. ; Renner, M. ; Bhatti, I. A. ; Hutter, B. ; Hüllein, J. ; Fröhlich, M. ; Uhrig, S. ; Süße, H. ; Heiligenthal, L. ; Ochsenreither, S. ; Illert, A. L. ; Vogel, A. ; Desuki, A. ; Heinemann, V. ; Heidegger, S. ; Bitzer, M. ; Scheytt, M. ; Brors, B. ; Hübschmann, D. ; Baretton, G. ; Stenzinger, A. ; Steindorf, K. ; Benner, A. ; Jäger, D. ; Heining, C. ; Glimm, H. ; Fröhling, S. ; Schlenk, R. F. Rationale and design of the CRAFT (Continuous ReAssessment with Flexible ExTension in Rare Malignancies) multicenter phase II trial.
ESMO open 6 (6 ), 100310 (2021 ) [10.1016/j.esmoop.2021.100310 ] 2021
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Khandanpour, C. ; Eisfeld, C. ; Nimmagadda, S. C. ; Raab, M. S. ; Weinhold, N. ; Seckinger, A. ; Hose, D. ; Jauch, A. ; Försti, A. ; Hemminki, K. ; Hielscher, T. ; Hummel, M. ; Lenz, G. ; Goldschmidt, H. ; Huhn, S. Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis.
Frontiers in oncology 11 , 757664 (2021 ) [10.3389/fonc.2021.757664 ] 2021
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Kiehl, L. (First author) ; Kuntz, S. ; Höhn, J. ; Jutzi, T. ; Krieghoff-Henning, E. ; Kather, J. N. ; Holland-Letz, T. ; Kopp-Schneider, A. ; Chang-Claude, J. ; Brobeil, A. ; von Kalle, C. ; Fröhling, S. ; Alwers, E. ; Brenner, H. ; Hoffmeister, M. ; Brinker, T. (Last author) Deep learning can predict lymph node status directly from histology in colorectal cancer.
European journal of cancer 157 , 464 - 473 (2021 ) [10.1016/j.ejca.2021.08.039 ] 2021
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Klein, E.-M. ; Tichy, D. ; Salwender, H. J. ; Mai, E. K. ; Duerig, J. ; Weisel, K. C. ; Benner, A. ; Bertsch, U. ; Akhavanpoor, M. ; Besemer, B. ; Munder, M. ; Lindemann, H.-W. ; Hose, D. ; Seckinger, A. ; Luntz, S. ; Jauch, A. ; Elmaagacli, A. ; Fuhrmann, S. ; Brossart, P. ; Goerner, M. ; Bernhard, H. ; Raab, M. S. ; Blau, I. W. ; Haenel, M. ; Scheid, C. ; Goldschmidt, H. ; On Behalf Of The German-Speaking Myeloma Multicenter Group Gmmg Prognostic Impact of Serum Free Light Chain Ratio Normalization in Patients with Multiple Myeloma Treated within the GMMG-MM5 Trial.
Cancers 13 (19 ), 4856 (2021 ) [10.3390/cancers13194856 ] 2021
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Maas, S. L. N. (First author) ; Stichel, D. ; Hielscher, T. ; et al Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated.
Journal of clinical oncology 39 (34 ), 3839-3852 (2021 ) [10.1200/JCO.21.00784 ] 2021
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Pouyiourou, M. (First author) ; Wohlfromm, T. ; Kraft, B. ; Hielscher, T. ; Stichel, D. ; von Deimling, A. ; Delorme, S. ; Endris, V. ; Neumann, O. ; Stenzinger, A. ; Krämer, A. ; Bochtler, T. (Last author) Local ablative treatment with surgery and/or radiotherapy in single-site and oligometastatic carcinoma of unknown primary.
European journal of cancer 157 , 179 - 189 (2021 ) [10.1016/j.ejca.2021.08.019 ] 2021
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Baertsch, M.-A. ; Fougereau, M. ; Hielscher, T. ; Sauer, S. ; Breitkreutz, I. ; Jordan, K. ; Müller-Tidow, C. ; Goldschmidt, H. ; Raab, M.-S. ; Hillengass, J. ; Giesen, N. (Last author) Carfilzomib, Lenalidomide, and Dexamethasone Followed by Salvage Autologous Stem Cell Transplant with or without Maintenance for Relapsed or Refractory Multiple Myeloma.
Cancers 13 (18 ), 4706 (2021 ) [10.3390/cancers13184706 ] 2021
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Sachpekidis, C. (First author) ; Merz, M. ; Raab, M.-S. ; Bertsch, U. ; Weru, V. ; Kopp-Schneider, A. ; Jauch, A. ; Goldschmidt, H. ; Dimitrakopoulou-Strauss, A. (Last author) The prognostic significance of [18F]FDG PET/CT in multiple myeloma according to novel interpretation criteria (IMPeTUs).
EJNMMI Research 11 (1 ), 100 (2021 ) [10.1186/s13550-021-00846-y ] 2021
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Bloehdorn, J. ; Braun, A. ; Taylor-Weiner, A. ; Jebaraj, B. M. C. ; Robrecht, S. ; Krzykalla, J. ; Pan, H. ; Giza, A. ; Akylzhanova, G. ; Holzmann, K. ; Scheffold, A. ; Johnston, H. E. ; Yeh, R.-F. ; Klymenko, T. ; Tausch, E. ; Eichhorst, B. ; Bullinger, L. ; Fischer, K. ; Weisser, M. ; Robak, T. ; Schneider, C. ; Gribben, J. ; Dahal, L. N. ; Carter, M. J. ; Elemento, O. ; Landau, D. A. ; Neuberg, D. S. ; Cragg, M. S. ; Benner, A. ; Hallek, M. ; Wu, C. J. ; Döhner, H. ; Stilgenbauer, S. ; Mertens, D. (Last author) Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia.
Nature Communications 12 (1 ), 5395 (2021 ) [10.1038/s41467-021-25403-y ] 2021
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Liang, H.-C. ; Costanza, M. ; Prutsch, N. ; Zimmerman, M. W. ; Gurnhofer, E. ; Montes-Mojarro, I. A. ; Abraham, B. J. ; Prokoph, N. ; Stoiber, S. ; Tangermann, S. ; Lobello, C. ; Oppelt, J. ; Anagnostopoulos, I. ; Hielscher, T. ; Pervez, S. ; Klapper, W. ; Zammarchi, F. ; Silva, D.-A. ; Garcia, K. C. ; Baker, D. ; Janz, M. ; Schleussner, N. ; Fend, F. ; Pospí?ilová, ?. ; Janiková, A. ; Wallwitz, J. ; Stoiber, D. ; Simonitsch-Klupp, I. ; Cerroni, L. ; Pileri, S. ; de Leval, L. ; Sibon, D. ; Fataccioli, V. ; Gaulard, P. ; Assaf, C. ; Knörr, F. ; Damm-Welk, C. ; Woessmann, W. ; Turner, S. D. ; Look, A. T. ; Mathas, S. ; Kenner, L. ; Merkel, O. Super-enhancer-based identification of a BATF3/IL-2R?module reveals vulnerabilities in anaplastic large cell lymphoma
Nature Communications 12 (1 ), 5577 (2021 ) [10.1038/s41467-021-25379-9 ] 2021
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Jain, D. ; Guleria, P. ; Singh, V. ; Parshad, R. ; Kumar, S. ; Gaiser, T. ; Kurz, K. S. ; Ott, G. ; Porubsky, S. ; Preissler, G. ; Sauer, C. G. ; Schölch, S. ; Ströbel, P. ; Hielscher, T. ; Marx, A. ; Popovic, Z. V. GTF2I Mutation in Thymomas: Independence From Racial-Ethnic Backgrounds. An Indian/German Comparative Study.
Pathology & oncology research 27 , 1609858 (2021 ) [10.3389/pore.2021.1609858 ] 2021
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Sachpekidis, C. (First author) ; Kopp-Schneider, A. ; Hassel, J. C. ; Dimitrakopoulou-Strauss, A. (Last author) Assessment of early metabolic progression in melanoma patients under immunotherapy: an 18F-FDG PET/CT study.
EJNMMI Research 11 (1 ), 89 (2021 ) [10.1186/s13550-021-00832-4 ] 2021
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Raut, J. (First author) ; Schöttker, B. ; Holleczek, B. ; Guo, F. ; Bhardwaj, M. ; Miah, K. ; Schrotz-King, P. ; Brenner, H. (Last author) A microRNA panel compared to environmental and polygenic scores for colorectal cancer risk prediction.
Nature Communications 12 (1 ), 4811 (2021 ) [10.1038/s41467-021-25067-8 ] 2021
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van Tilburg, C. M. ; Pfaff, E. ; Pajtler, K. W. ; et al The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets.
Cancer discovery 11 (11 ), 2764-2779 (2021 ) [10.1158/2159-8290.CD-21-0094 ] 2021
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Basset, M. ; Kimmich, C. R. ; Schreck, N. ; Krzykalla, J. ; Dittrich, T. ; Veelken, K. ; Goldschmidt, H. ; Seckinger, A. ; Hose, D. ; Jauch, A. ; Müller-Tidow, C. ; Benner, A. ; Hegenbart, U. ; Schönland, S. O. Lenalidomide and dexamethasone in relapsed/refractory immunoglobulin light chain (AL) amyloidosis: results from a large cohort of patients with long follow-up.
British journal of haematology 195 (2 ), 230-243 (2021 ) [10.1111/bjh.17685 ] 2021
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Klein, E.-M. ; Sauer, S. ; Klein, S. ; Tichy, D. ; Benner, A. ; Bertsch, U. ; Brandt, J. ; Kimmich, C. ; Goldschmidt, H. ; Müller-Tidow, C. ; Jordan, K. ; Giesen, N. Antibiotic Prophylaxis or Granulocyte-Colony Stimulating Factor Support in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation.
Cancers 13 (14 ), 3439 (2021 ) [10.3390/cancers13143439 ] 2021
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Gies, A. (First author) ; Niedermaier, T. (First author) ; Alwers, E. ; Hielscher, T. ; Weigl, K. ; Heisser, T. ; Schrotz-King, P. ; Hoffmeister, M. ; Brenner, H. (Last author) Consistent Major Differences in Sex- and Age-Specific Diagnostic Performance among Nine Faecal Immunochemical Tests Used for Colorectal Cancer Screening.
Cancers 13 (14 ), 3574 - (2021 ) [10.3390/cancers13143574 ] 2021
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Bajwa-Ten Broeke, S. W. ; Ballhausen, A. ; Ahadova, A. ; Suerink, M. ; Bohaumilitzky, L. ; Seidler, F. ; Morreau, H. ; van Wezel, T. ; Krzykalla, J. ; Benner, A. ; de Miranda, N. F. ; von Knebel Doeberitz, M. ; Nielsen, M. ; Kloor, M. (Last author) The coding microsatellite mutation profile of PMS2-deficient colorectal cancer.
Experimental and molecular pathology 122 , 104668 (2021 ) [10.1016/j.yexmp.2021.104668 ] 2021
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Dieter, S. (First author) ; Siegl, C. ; Codo, P. L. ; Huerta, M. ; Ostermann-Parucha, A. L. ; Schulz, E. ; Zowada, M. K. ; Martin, S. ; Laaber, K. ; Nowrouzi, A. ; Blatter, M. ; Kreth, S. ; Westermann, F. ; Benner, A. ; Uhrig, U. ; Putzker, K. ; Lewis, J. ; Haegebarth, A. ; Mumberg, D. ; Holton, S. J. ; Weiske, J. ; Toepper, L.-M. ; Scheib, U. ; Siemeister, G. ; Ball, C. R. ; Kuster, B. ; Stoehr, G. ; Hahne, H. ; Johannes, S. ; Lange, M. ; Herbst, F. ; Glimm, H. Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer.
Cell reports 36 (3 ), 109394 (2021 ) [10.1016/j.celrep.2021.109394 ] 2021
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Luft, T. ; Wendtner, C.-M. ; Kosely, F. ; Radujkovic, A. ; Benner, A. ; Korell, F. ; Kihm, L. ; Bauer, M. F. ; Dreger, P. ; Merle, U. EASIX for Prediction of Outcome in Hospitalized SARS-CoV-2 Infected Patients
Frontiers in immunology 12 , 634416 (2021 ) [10.3389/fimmu.2021.634416 ] 2021
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Sicklinger, F. ; Meyer, I. S. ; Li, X. ; Radtke, D. ; Dicks, S. ; Kornadt, M. P. ; Mertens, C. ; Meier, J. K. ; Lavine, K. J. ; Zhang, Y. ; Kuhn, T. C. ; Terzer, T. ; Patel, J. ; Börries, M. ; Schramm, G. ; Frey, N. ; Katus, H. A. ; Voehringer, D. ; Leuschner, F. Basophils balance healing after myocardial infarction via IL-4/IL-13.
The journal of clinical investigation 131 (13 ), e136778 (2021 ) [10.1172/JCI136778 ] 2021
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Porubsky, S. ; Nientiedt, M. ; Kriegmair, M. C. ; Siemoneit, J. H. ; Sandhoff, R. ; Jennemann, R. ; Borgmann, H. ; Gaiser, T. ; Weis, C.-A. ; Erben, P. ; Hielscher, T. ; Popovic, Z. V. The prognostic value of galactosylceramide-sulfotransferase (Gal3ST1) in human renal cell carcinoma.
Scientific reports 11 (1 ), 10926 (2021 ) [10.1038/s41598-021-90381-6 ] 2021
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Zhang, K. S. (First author) ; Schelb, P. ; Kohl, S. ; Radtke, J. P. ; Wiesenfarth, M. ; Schimmöller, L. ; Kuder, T. A. ; Stenzinger, A. ; Hohenfellner, M. ; Schlemmer, H.-P. ; Maier-Hein, K. ; Bonekamp, D. (Last author) Improvement of PI-RADS-dependent prostate cancer classification by quantitative image assessment using radiomics or mean ADC.
Magnetic resonance imaging 82 , 9-17 (2021 ) [10.1016/j.mri.2021.06.013 ] 2021
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Weinhold, N. ; Salwender, H. J. ; Cairns, D. A. ; Raab, M. S. ; Waldron, G. ; Blau, I. W. ; Bertsch, U. ; Hielscher, T. ; Morgan, G. J. ; Jauch, A. ; Davies, F. E. ; Hänel, M. ; Cook, G. ; Scheid, C. ; Houlston, R. ; Goldschmidt, H. ; Jackson, G. ; Kaiser, M. F. Chromosome 1q21 abnormalities refine outcome prediction in patients with multiple myeloma - a meta-analysis of 2,596 trial patients.
Haematologica 106 (10 ), 2754-2758 (2021 ) [10.3324/haematol.2021.278888 ] 2021
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Teich, K. ; Krzykalla, J. ; Kapp-Schwoerer, S. ; Gaidzik, V. I. ; Schlenk, R. F. ; Paschka, P. ; Weber, D. ; Fiedler, W. ; Kühn, M. W. M. ; Schroeder, T. ; Mayer, K. ; Lübbert, M. ; Ramachandran, D. ; Benner, A. ; Ganser, A. ; Döhner, H. ; Heuser, M. ; Döhner, K. ; Thol, F. Cluster of differentiation 33 single nucleotide polymorphism rs12459419 is a predictive factor in patients with nucleophosmin1 mutated acute myeloid leukemia receiving gemtuzumab ozogamicin.
Haematologica 106 (11 ), 2986-2989 (2021 ) [10.3324/haematol.2021.278894 ] 2021
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Netzer, N. (First author) ; Weißer, C. ; Schelb, P. ; Wang, X. ; Qin, X. ; Görtz, M. ; Schütz, V. ; Radtke, J. P. ; Hielscher, T. ; Schwab, C. ; Stenzinger, A. ; Kuder, T. A. ; Gnirs, R. ; Hohenfellner, M. ; Schlemmer, H.-P. ; Maier-Hein, K. H. ; Bonekamp, D. (Last author) Fully Automatic Deep Learning in Bi-institutional Prostate Magnetic Resonance Imaging: Effects of Cohort Size and Heterogeneity.
Investigative radiology 56 (12 ), 799-808 (2021 ) [10.1097/RLI.0000000000000791 ] 2021
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Salwender, H. ; Elmaagacli, A. ; Merz, M. ; Miah, K. ; Benner, A. ; Haenel, M. ; Jehn, C. ; Mai, E. K. ; Bertsch, U. ; Blau, I. W. ; Scheid, C. ; Hose, D. ; Seckinger, A. ; Jauch, A. ; Raab, M. S. ; Luntz, S. P. ; Besemer, B. ; Munder, M. ; Brossart, P. ; Fuhrmann, S. ; Lindemann, H.-W. ; Weisel, K. ; Duerig, J. ; Goldschmidt, H. Long-term follow-up of subcutaneous versus intravenous bortezomib during induction therapy for newly diagnosed multiple myeloma treated within the GMMG-MM5 Phase III Trial.
Leukemia 35 (10 ), 3007-3011 (2021 ) [10.1038/s41375-021-01298-y ] 2021
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Riedl, T. (First author) ; Faure-Dupuy, S. ; Rolland, M. ; Schuehle, S. ; Hizir, Z. ; Calderazzo, S. ; Zhuang, X. ; Wettengel, J. ; Lopez, M. A. ; Barnault, R. ; Mirakaj, V. ; Prokosch, S. ; Heide, D. ; Leuchtenbergeg, C. ; Schneider, M. ; Heßling, B. ; Stottmeier, B. ; Wessbecher, I. M. ; Schirmacher, P. ; McKeating, J. A. ; Protzer, U. ; Durantel, D. ; Lucifora, J. ; Dejardin, E. ; Heikenwälder, M. (Last author) HIF1?-mediated RelB/APOBEC3B downregulation allows Hepatitis B Virus persistence.
Hepatology 74 (4 ), 1766-1781 (2021 ) [10.1002/hep.31902 ] 2021
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Wiesenfarth, M. (First author) ; Reinke, A. ; Landman, B. A. ; Eisenmann, M. ; Saiz, L. A. ; Cardoso, M. J. ; Maier-Hein, L. ; Kopp-Schneider, A. (Last author) Author Correction: Methods and open-source toolkit for analyzing and visualizing challenge results.
Scientific reports 11 (1 ), 10144 (2021 ) [10.1038/s41598-021-88636-3 ] 2021
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Maier-Hein, L. (First author) ; Wagner, M. ; Ross, T. ; Reinke, A. ; Bodenstedt, S. ; Full, P. M. ; Hempe, H. ; Mindroc-Filimon, D. ; Scholz, P. ; Tran, T. N. ; Bruno, P. ; Kisilenko, A. ; Müller, B. ; Davitashvili, T. ; Capek, M. ; Tizabi, M. D. ; Eisenmann, M. ; Adler, T. J. ; Gröhl, J. ; Schellenberg, M. ; Seidlitz, S. ; Lai, T. Y. E. ; Pekdemir, B. ; Roethlingshoefer, V. ; Both, F. ; Bittel, S. ; Mengler, M. ; Mündermann, L. ; Apitz, M. ; Kopp-Schneider, A. ; Speidel, S. ; Nickel, F. ; Probst, P. ; Kenngott, H. G. ; Müller-Stich, B. P. Heidelberg colorectal data set for surgical data science in the sensor operating room.
Scientific data 8 (1 ), 101 (2021 ) [10.1038/s41597-021-00882-2 ] 2021
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Kimmich, C. R. ; Terzer, T. ; Benner, A. ; Hansen, T. ; Carpinteiro, A. ; Dittrich, T. ; Veelken, K. ; Jauch, A. ; Huhn, S. ; Basset, M. ; Goldschmidt, H. ; Müller-Tidow, C. ; Schönland, S. O. ; Hegenbart, U. Daratumumab, lenalidomide, and dexamethasone in systemic light-chain amyloidosis: High efficacy, relevant toxicity and main adverse effect of gain 1q21
American journal of hematology 96 (7 ), E253-E257 (2021 ) [10.1002/ajh.26191 ] 2021
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Seydel, F. ; Delecluse, S. (First author) ; Zeier, M. ; Holland-Letz, T. ; Haag, G. M. ; Berger, A. K. ; Grün, B. C. ; Bougatf, N. ; Hohenfellner, M. ; Duensing, S. ; Jäger, D. ; Zschäbitz, S. Efficacy and Safety of Checkpoint Inhibitor Treatment in Patients with Advanced Renal or Urothelial Cell Carcinoma and Concomitant Chronic Kidney Disease: A Retrospective Cohort Study
Cancers 13 (7 ), 1623 (2021 ) [10.3390/cancers13071623 ] 2021
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Sachpekidis, C. (First author) ; Hassel, J. C. ; Kopp-Schneider, A. ; Haberkorn, U. ; Dimitrakopoulou-Strauss, A. (Last author) Quantitative Dynamic 18F-FDG PET/CT in Survival Prediction of Metastatic Melanoma under PD-1 Inhibitors.
Cancers 13 (5 ), 1019 (2021 ) [10.3390/cancers13051019 ] 2021
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Koerber, S. A. ; Boesch, J. ; Kratochwil, C. ; Schlampp, I. ; Ristau, J. ; Winter, E. ; Zschaebitz, S. ; Hofer, L. ; Herfarth, K. ; Kopka, K. ; Holland-Letz, T. ; Jaeger, D. ; Hohenfellner, M. ; Haberkorn, U. ; Debus, J. ; Giesel, F. (Last author) Predicting the Risk of Metastases by PSMA-PET/CT-Evaluation of 335 Men with Treatment-Naïve Prostate Carcinoma.
Cancers 13 (7 ), 1508 (2021 ) [10.3390/cancers13071508 ] 2021
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Thomas, C. ; Thierfelder, F. ; Träger, M. ; Soschinski, P. ; Müther, M. ; Edelmann, D. ; Förster, A. ; Geiler, C. ; Kim, H.-Y. ; Filipski, K. ; Harter, P. ; Schittenhelm, J. ; Eckert, F. ; Ntoulias, G. ; May, S.-A. ; Stummer, W. ; Onken, J. ; Vajkoczy, P. ; Schüller, U. ; Heppner, F. L. ; Capper, D. ; Koch, A. ; Kaul, D. ; Paulus, W. ; Hasselblatt, M. ; Schweizer, L. TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma.
Acta neuropathologica 141 (6 ), 959-970 (2021 ) [10.1007/s00401-021-02300-8 ] 2021
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Wennmann, M. (First author) ; Hielscher, T. ; Kintzelé, L. ; Menze, B. H. ; Langs, G. ; Merz, M. ; Sauer, S. ; Kauczor, H.-U. ; Schlemmer, H.-P. ; Delorme, S. ; Goldschmidt, H. ; Weinhold, N. ; Hillengass, J. ; Weber, M.-A. Analyzing Longitudinal wb-MRI Data and Clinical Course in a Cohort of Former Smoldering Multiple Myeloma Patients: Connections between MRI Findings and Clinical Progression Patterns
Cancers 13 (5 ), 961 (2021 ) [10.3390/cancers13050961 ] 2021
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Awwad, M. H. S. ; Mahmoud, A. ; Bruns, H. ; Echchannaoui, H. ; Kriegsmann, K. ; Lutz, R. ; Raab, M.-S. ; Bertsch, U. ; Munder, M. ; Jauch, A. ; Weisel, K. ; Maier, B. ; Weinhold, N. ; Salwender, H. J. ; Eckstein, V. ; Hänel, M. ; Fenk, R. ; Dürig, J. ; Brors, B. ; Benner, A. ; Müller-Tidow, C. ; Goldschmidt, H. ; Hundemer, M. Selective elimination of immunosuppressive T cells in patients with multiple myeloma.
Leukemia 35 (9 ), 2602-2615 (2021 ) [10.1038/s41375-021-01172-x ] 2021
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Afshar-Oromieh, A. ; da Cunha, M. L. ; Wagner, J. ; Haberkorn, U. ; Debus, N. ; Weber, W. ; Eiber, M. ; Holland-Letz, T. (Last author) ; Rauscher, I. Performance of [68Ga]Ga-PSMA-11 PET/CT in patients with recurrent prostate cancer after prostatectomy-a multi-centre evaluation of 2533 patients.
European journal of nuclear medicine and molecular imaging 48 (9 ), 2925-2934 (2021 ) [10.1007/s00259-021-05189-3 ] 2021
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Bhardwaj, M. (First author) ; Terzer, T. ; Schrotz-King, P. ; Brenner, H. (Last author) Comparison of Proteomic Technologies for Blood-Based Detection of Colorectal Cancer.
International journal of molecular sciences 22 (3 ), 1189 (2021 ) [10.3390/ijms22031189 ] 2021
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Kappenberg, F. ; Grinberg, M. ; Jiang, X. ; Kopp-Schneider, A. ; Hengstler, J. G. ; Rahnenführer, J. Comparison Of Observation-Based And Model-Based Identification Of Alert Concentrations From Concentration-Expression Data.
Bioinformatics 37 (14 ), 1990-1996 (2021 ) [10.1093/bioinformatics/btab043 ] 2021
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Wiesenfarth, M. (First author) ; Reinke, A. ; Landman, B. A. ; Eisenmann, M. ; Saiz, L. A. ; Cardoso, M. J. ; Maier-Hein, L. ; Kopp-Schneider, A. (Last author) Methods and open-source toolkit for analyzing and visualizing challenge results.
Scientific reports 11 (1 ), 2369 (2021 ) [10.1038/s41598-021-82017-6 ] 2021
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Wang, X. (First author) ; Hielscher, T. ; Radtke, J. P. ; Görtz, M. ; Schütz, V. ; Kuder, T. A. ; Gnirs, R. ; Schwab, C. ; Stenzinger, A. ; Hohenfellner, M. ; Schlemmer, H.-P. ; Bonekamp, D. (Last author) Comparison of single-scanner single-protocol quantitative ADC measurements to ADC ratios to detect clinically significant prostate cancer.
European journal of radiology 136 , 109538 (2021 ) [10.1016/j.ejrad.2021.109538 ] 2021
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Baertsch, M.-A. ; Mai, E. K. ; Hielscher, T. ; Bertsch, U. ; Salwender, H. J. ; Munder, M. ; Fuhrmann, S. ; Dührsen, U. ; Brossart, P. ; Neben, K. ; Schlenzka, J. ; Kunz, C. ; Raab, M. S. ; Hillengaß, J. ; Jauch, A. ; Seckinger, A. ; Hose, D. ; Luntz, S. ; Sonneveld, P. ; Lokhorst, H. ; Martin, H. ; Goerner, M. ; Hoffmann, M. ; Lindemann, H.-W. ; Bernhard, H. ; Blau, I. W. ; Scheid, C. ; Besemer, B. ; Weisel, K. C. ; Hänel, M. ; Dürig, J. ; Goldschmidt, H. ; Group, G. M. M. (Collaboration Author) Lenalidomide versus bortezomib maintenance after frontline autologous stem cell transplantation for multiple myeloma.
Blood cancer journal 11 (1 ), 1 (2021 ) [10.1038/s41408-020-00390-3 ] 2021
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Gebhardt, C. (First author) ; Simon, S. C. S. ; Weber, R. ; Gries, M. ; Mun, D. H. ; Reinhard, R. ; Holland-Letz, T. ; Umansky, V. ; Utikal, J. (Last author) Potential therapeutic effect of low-dose paclitaxel in melanoma patients resistant to immune checkpoint blockade: A pilot study.
Cellular immunology 360 , 104274 (2021 ) [10.1016/j.cellimm.2020.104274 ] 2021
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Sachpekidis, C. (First author) ; Kopp-Schneider, A. ; Pan, L. ; Papamichail, D. ; Haberkorn, U. ; Hassel, J. C. ; Dimitrakopoulou-Strauss, A. (Last author) Interim [18F]FDG PET/CT can predict response to anti-PD-1 treatment in metastatic melanoma.
European journal of nuclear medicine and molecular imaging 48 (6 ), 1932-1943 (2021 ) [10.1007/s00259-020-05137-7 ] 2021
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Holland-Letz, T. (First author) ; Kopp-Schneider, A. (Last author) An R-shiny application to calculate optimal designs for single substance and interaction trials in dose response experiments.
Toxicology letters 337 , 18 - 27 (2021 ) [10.1016/j.toxlet.2020.11.018 ] 2021
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Ross, T. (First author) ; Reinke, A. ; Full, P. M. ; Wagner, M. ; Kenngott, H. ; Apitz, M. ; Hempe, H. ; Mindroc Filimon, D. ; Scholz, P. ; Tran, T. N. ; Bruno, P. ; Arbeláez, P. ; Bian, G.-B. ; Bodenstedt, S. ; Bolmgren, J. L. ; Bravo-Sánchez, L. ; Chen, H.-B. ; González, C. ; Guo, D. ; Halvorsen, P. ; Heng, P.-A. ; Hosgor, E. ; Hou, Z.-G. ; Isensee, F. ; Jha, D. ; Jiang, T. ; Jin, Y. ; Kirtac, K. ; Kletz, S. ; Leger, S. ; Li, Z. ; Maier-Hein, K. H. ; Ni, Z.-L. ; Riegler, M. A. ; Schoeffmann, K. ; Shi, R. ; Speidel, S. ; Stenzel, M. ; Twick, I. ; Wang, G. ; Wang, J. ; Wang, L. ; Wang, L. ; Zhang, Y. ; Zhou, Y.-J. ; Zhu, L. ; Wiesenfarth, M. ; Kopp-Schneider, A. ; Müller-Stich, B. P. ; Maier-Hein, L. (Last author) Comparative validation of multi-instance instrument segmentation in endoscopy: results of the ROBUST-MIS 2019 challenge
Medical image analysis 70 , 101920 (2021 ) [10.1016/j.media.2020.101920 ] 2021
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Schelb, P. (First author) ; Tavakoli, A. A. ; Tubtawee, T. ; Hielscher, T. ; Radtke, J.-P. ; Görtz, M. ; Schütz, V. ; Kuder, T. A. ; Schimmöller, L. ; Stenzinger, A. ; Hohenfellner, M. ; Schlemmer, H.-P. ; Bonekamp, D. (Last author) Comparison of Prostate MRI Lesion Segmentation Agreement Between Multiple Radiologists and a Fully Automatic Deep Learning System.[Vergleich der Kongruenz von Prostata-MRT-Läsionssegmentationen durch mehrere Radiologen und ein vollautomatisches Deep-Learning-System].
Ro?Fo 193 (5 ), 559-573 (2021 ) [10.1055/a-1290-8070 ] 2021
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Edelmann, D. (First author) ; Móri, T. F. ; Székely, G. J. On relationships between the Pearson and the distance correlation coefficients
Statistics & probability letters 169 , 108960 (2021 ) [10.1016/j.spl.2020.108960 ] 2021
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Tavakoli, A. A. (First author) ; Kuder, T. A. ; Tichy, D. ; Radtke, J. P. ; Görtz, M. ; Schütz, V. ; Stenzinger, A. ; Hohenfellner, M. ; Schlemmer, H.-P. ; Bonekamp, D. (Last author) Measured Multipoint Ultra-High b-Value Diffusion MRI in the Assessment of MRI-Detected Prostate Lesions.
Investigative radiology 56 (2 ), 94-102 (2021 ) [10.1097/RLI.0000000000000712 ] 2021
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Kopp-Schneider, A. (Last author) Comments on 'Incorporating historical two-arm data in clinical trials with binary outcome: A practical approach' by Manuel Feißt, Johannes Krisam and Meinhard Kieser.
Pharmaceutical statistics 20 (1 ), 196-198 (2021 ) [10.1002/pst.2061 ] 2021
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Radtke, J. P. (First author) ; Nyarangi-Dix, J. ; Wiesenfarth, M. ; Hadaschik, B. Re: The Key Combined Value of Multiparametric Magnetic Resonance Imaging, and Magnetic Resonance Imaging-targeted and Concomitant Systematic Biopsies for the Prediction of Adverse Pathological Features in Prostate Cancer Patients Undergoing Radical Prostatectomy.
European urology 79 (1 ), 164-165 (2021 ) [10.1016/j.eururo.2020.08.019 ] 2021
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Sprute, K. ; Kramer, V. ; Koerber, S. ; Meneses, M. ; Fernandez, R. ; Soza-Ried, C. ; Eiber, M. ; Weber, W. ; Rauscher, I. ; Rahbar, K. ; Schaefers, M. ; Watabe, T. ; Uemura, M. ; Naka, S. ; Nonomura, N. ; Hatazawa, J. ; Schwab, C. ; Schütz, V. ; Hohenfellner, M. ; Holland-Letz, T. ; Debus, J. ; Kratochwil, C. ; Amaral, H. ; Choyke, P. L. ; Haberkorn, U. ; Sandoval, C. ; Giesel, F. L. Diagnostic accuracy of 18F-PSMA-1007-PET/CT imaging for lymph node staging of prostate carcinoma in primary and biochemical recurrence.
Journal of nuclear medicine 62 (2 ), 208-213 (2021 ) [10.2967/jnumed.120.246363 ] 2021
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Schelb, P. (First author) ; Wang, X. ; Radtke, J. P. ; Wiesenfarth, M. ; Kickingereder, P. ; Stenzinger, A. ; Hohenfellner, M. ; Schlemmer, H.-P. ; Maier-Hein, K. H. ; Bonekamp, D. (Last author) Simulated clinical deployment of fully automatic deep learning for clinical prostate MRI assessment.
European radiology 31 (1 ), 302-313 (2021 ) [10.1007/s00330-020-07086-z ] 2021
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Mai, E. K. ; Miah, K. ; Bertsch, U. ; Dürig, J. ; Scheid, C. ; Weisel, K. C. ; Kunz, C. ; Munder, M. ; Lindemann, H.-W. ; Merz, M. ; Hose, D. ; Jauch, A. ; Seckinger, A. ; Luntz, S. ; Sauer, S. ; Fuhrmann, S. ; Brossart, P. ; Elmaagacli, A. ; Goerner, M. ; Bernhard, H. ; Hoffmann, M. ; Raab, M. S. ; Blau, I. W. ; Hänel, M. ; Benner, A. ; Salwender, H. J. ; Goldschmidt, H. ; Group, G. M. M. (Collaboration Author) Bortezomib-based induction, high-dose melphalan and lenalidomide maintenance in myeloma up to 70 years of age.
Leukemia 35 (3 ), 809-822 (2021 ) [10.1038/s41375-020-0976-9 ] 2021
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Goldschmidt, H. ; Baertsch, M.-A. ; Schlenzka, J. ; Becker, N. ; Habermehl, C. ; Hielscher, T. ; Raab, M.-S. ; Hillengass, J. ; Sauer, S. ; Müller-Tidow, C. ; Luntz, S. ; Jauch, A. ; Hose, D. ; Seckinger, A. ; Brossart, P. ; Goerner, M. ; Klein, S. ; Schmidt-Hieber, M. ; Reimer, P. ; Graeven, U. ; Fenk, R. ; Haenel, M. ; Martin, H. ; Lindemann, H. W. ; Scheid, C. ; Nogai, A. ; Salwender, H. ; Noppeney, R. ; Besemer, B. ; Weisel, K. ; Group, G. M. M. (Collaboration Author) Salvage autologous transplant and lenalidomide maintenance vs. lenalidomide/dexamethasone for relapsed multiple myeloma: the randomized GMMG phase III trial ReLApsE.
Leukemia 35 (4 ), 1134-1144 (2021 ) [10.1038/s41375-020-0948-0 ] 2021
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Tschirdewahn, S. ; Wiesenfarth, M. ; Bonekamp, D. ; Püllen, L. ; Reis, H. ; Panic, A. ; Kesch, C. ; Darr, C. ; Heß, J. ; Giganti, F. ; Moore, C. M. ; Guberina, N. ; Forsting, M. ; Wetter, A. ; Hadaschik, B. ; Radtke, J. P. (Last author) Detection of Significant Prostate Cancer Using Target Saturation in Transperineal Magnetic Resonance Imaging/Transrectal Ultrasonography-fusion Biopsy.
European urology focus 7 (6 ), 1300-1307 (2021 ) [10.1016/j.euf.2020.06.020 ] 2021
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Koerber, S. A. ; Sprute, K. ; Kratochwil, C. ; Winter, E. ; Haefner, M. F. ; Katayama, S. ; Schlampp, I. ; Herfarth, K. ; Kopka, K. ; Afshar-Oromieh, A. ; Zschaebitz, S. ; Holland-Letz, T. ; Choyke, P. L. ; Jaeger, D. ; Hohenfellner, M. ; Haberkorn, U. ; Debus, J. ; Giesel, F. (Last author) Clinical outcome of PSMA-guided radiotherapy for patients with oligorecurrent prostate cancer.
European journal of nuclear medicine and molecular imaging 48 (1 ), 143-151 (2021 ) [10.1007/s00259-020-04777-z ] 2021
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Jiang, S. ; Penack, O. ; Terzer, T. ; Schult, D. ; Majer-Lauterbach, J. ; Radujkovic, A. ; Blau, I. W. ; Bullinger, L. ; Müller-Tidow, C. ; Dreger, P. ; Luft, T. Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel.
Haematologica 106 (2 ), 446-453 (2021 ) [10.3324/haematol.2019.238790 ] 2021
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Sachpekidis, C. ; Sachpekidis, V. ; Kopp-Schneider, A. ; Arsos, G. ; Moralidis, E. Equilibrium radionuclide angiography: Intra- and inter-observer repeatability and reproducibility in the assessment of cardiac systolic and diastolic function.
Journal of nuclear cardiology 28 (4 ), 1304-1314 (2021 ) [10.1007/s12350-019-01830-9 ] 2021
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