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Research

Publications 2019

Püllen, L. ; Radtke, J. P. ; Wiesenfarth, M. ; Roobol, M. J. ; Verbeek, J. F. M. ; Wetter, A. ; Guberina, N. ; Pandey, A. ; Hüttenbrink, C. ; Tschirdewahn, S. ; Pahernik, S. ; Hadaschik, B. A. ; Distler, F. A.
External validation of novel MRI-based models for prostate cancer prediction.
BJU international 125(3), 407-416 (2019) [10.1111/bju.14958]2019 BibTeX | EndNote: XML, Text | RIS

Luft, T. ; Benner, A. ; Terzer, T. ; Jodele, S. ; Dandoy, C. E. ; Storb, R. ; Kordelas, L. ; Beelen, D. ; Gooley, T. ; Sandmaier, B. M. ; Sorror, M. ; Zeisbrich, M. ; Radujkovic, A. ; Dreger, P. ; Penack, O.
EASIX and mortality after allogeneic stem cell transplantation.
Bone marrow transplantation 55(3), 553-561 (2019) [10.1038/s41409-019-0703-1]2019 BibTeX | EndNote: XML, Text | RIS

Röhrich, M. ; Loktev, A. ; Wefers, A. ; Paech, D. ; Adeberg, S. ; Windisch, P. ; Hielscher, T. ; Flechsig, P. ; Floca, R. ; Debus, J. ; Deimling, A. ; Lindner, T. ; Haberkorn, U.
Fibroblast Activation Protein specific PET: A novel imaging method for IDH-wildtype Glioblastomas and IDH-mutant Gliomas
2019NuklearMedizin 2019, BremenBremen, 3 Apr 2019 - 6 Apr 20192019-04-032019-04-06 Nuklearmedizin 58(02), 123-124 (2019) [10.1055/s-0039-1683524]2019 BibTeX | EndNote: XML, Text | RIS

van Tilburg, C. M. (First author) ; Milde, T. (First author) ; Witt, R. ; Ecker, J. ; Hielscher, T. ; Seitz, A. ; Schenk, J.-P. ; Buhl, J. L. ; Riehl, D. ; Frühwald, M. C. ; Pekrun, A. ; Rossig, C. ; Wieland, R. ; Flotho, C. ; Kordes, U. ; Gruhn, B. ; Simon, T. ; Linderkamp, C. ; Sahm, F. ; Taylor, L. ; Freitag, A. ; Burhenne, J. ; Foerster, K. I. ; Meid, A. D. ; Pfister, S. M. ; Karapanagiotou-Schenkel, I. ; Witt, O. (Last author)
Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia
Clinical epigenetics 11(1), 188 (2019) [10.1186/s13148-019-0775-1]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Wagner, N. B. (First author) ; Weide, B. ; Gries, M. ; Reith, M. ; Tarnanidis, K. ; Schuermans, V. ; Kemper, C. ; Kehrel, C. ; Funder, A. ; Lichtenberger, R. ; Sucker, A. ; Herpel, E. ; Holland-Letz, T. ; Schadendorf, D. ; Garbe, C. ; Umansky, V. ; Utikal, J. ; Gebhardt, C. (Last author)
Tumor microenvironment-derived S100A8/A9 is a novel prognostic biomarker for advanced melanoma patients and during immunotherapy with anti-PD-1 antibodies.
Journal for ImmunoTherapy of Cancer 7(1), 343 (2019) [10.1186/s40425-019-0828-1]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Neumeyer, S. M. (First author) ; Popanda, O. ; Butterbach, K. ; Edelmann, D. ; Bläker, H. ; Toth, C. ; Roth, W. ; Herpel, E. ; Jäkel, C. ; Schmezer, P. ; Benner, A. ; Burwinkel, B. ; Hoffmeister, M. ; Brenner, H. ; Chang-Claude, J. (Last author)
DNA methylation profiling to explore colorectal tumor differences according to menopausal hormone therapy use in women.
Epigenomics 11(16), 1765-1778 (2019) [10.2217/epi-2019-0051]2019 BibTeX | EndNote: XML, Text | RIS

Merz, A. ; Germing, U. ; Kobbe, G. ; Kaivers, J. ; Jauch, A. ; Radujkovic, A. ; Hummel, M. ; Benner, A. ; Merz, M. ; Dreger, P. ; Luft, T.
EASIX for prediction of survival in lower-risk myelodysplastic syndromes.
Blood cancer journal 9(11), 85 (2019) [10.1038/s41408-019-0247-z]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Maier-Hein, K. (First author) ; Neher, P. ; Houde, J.-C. ; et al
Author Correction: The challenge of mapping the human connectome based on diffusion tractography.
Nature Communications 10(1), 5059 (2019) [10.1038/s41467-019-12867-2]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Jung, A. Y. (First author) ; Behrens, S. ; Schmidt, M. ; Thoene, K. ; Obi, N. ; Hüsing, A. ; Benner, A. ; Steindorf, K. ; Chang-Claude, J. (Last author)
Pre- to postdiagnosis leisure-time physical activity and prognosis in postmenopausal breast cancer survivors.
Breast cancer research 21(1), 117 (2019) [10.1186/s13058-019-1206-0]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Edelmann, D. (Last author)
Generalized linear models with examples in R
Biometrical journal nn, bimj.201900264 (2019) [10.1002/bimj.201900264]2019 BibTeX | EndNote: XML, Text | RIS

Schelb, P. (First author) ; Kohl, S. ; Radtke, J. P. ; Wiesenfarth, M. ; Kickingereder, P. ; Bickelhaupt, S. ; Kuder, T. A. ; Stenzinger, A. ; Hohenfellner, M. ; Schlemmer, H.-P. ; Maier-Hein, K. ; Bonekamp, D. (Last author)
Classification of Cancer at Prostate MRI: Deep Learning versus Clinical PI-RADS Assessment.
Radiology 293(3), 607-617 (2019) [10.1148/radiol.2019190938]2019 BibTeX | EndNote: XML, Text | RIS

Schwarz, D. (First author) ; Niederle, T. ; Münch, P. ; Hielscher, T. ; Hassel, J. C. ; Schlemmer, H.-P. ; Platten, M. ; Winkler, F. ; Wick, W. ; Heiland, S. ; Delorme, S. ; Bendszus, M. ; Bäumer, P. ; Breckwoldt, M. (Last author)
Susceptibility-weighted imaging in malignant melanoma brain metastasis.
Journal of magnetic resonance imaging 50(4), 1251 - 1259 (2019) [10.1002/jmri.26692]2019 BibTeX | EndNote: XML, Text | RIS

Herling, C. D. ; Coombes, K. R. ; Benner, A. ; Bloehdorn, J. ; Barron, L. L. ; Abrams, Z. B. ; Majewski, T. ; Bondaruk, J. E. ; Bahlo, J. ; Fischer, K. ; Hallek, M. ; Stilgenbauer, S. ; Czerniak, B. A. ; Oakes, C. C. ; Ferrajoli, A. ; Keating, M. J. ; Abruzzo, L. V.
Time-to-progression after front-line fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy for chronic lymphocytic leukaemia: a retrospective, multicohort study.
The lancet <London> / Oncology Oncology 20(11), 1576-1586 (2019) [10.1016/S1470-2045(19)30503-0]2019 BibTeX | EndNote: XML, Text | RIS

Kopp-Schneider, A. (First author) ; Hielscher, T. (Last author)
How to evaluate agreement between quantitative measurements.
Radiotherapy and oncology 141, 321-326 (2019) [10.1016/j.radonc.2019.09.004]2019 BibTeX | EndNote: XML, Text | RIS

Delecluse, S. (First author) ; Yu, J. ; Bernhardt, K. ; Haar, J. ; Poirey, R. ; Tsai, M.-H. ; Kiblawi, R. ; Kopp-Schneider, A. ; Schnitzler, P. ; Zeier, M. ; Dreger, P. ; Wuchter, P. ; Bulut, O. C. ; Behrends, U. ; Delecluse, H.-J. (Last author)
Spontaneous lymphoblastoid cell lines from patients with Epstein-Barr virus infection show highly variable proliferation characteristics that correlate with the expression levels of viral microRNAs.
PLOS ONE 14(9), e0222847 - (2019) [10.1371/journal.pone.0222847]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Menzer, C. ; Menzies, A. M. ; Carlino, M. S. ; Reijers, I. ; Groen, E. J. ; Eigentler, T. ; de Groot, J. W. B. ; van der Veldt, A. A. M. ; Johnson, D. B. ; Meiss, F. ; Schlaak, M. ; Schilling, B. ; Westgeest, H. M. ; Gutzmer, R. ; Pföhler, C. ; Meier, F. ; Zimmer, L. ; Suijkerbuijk, K. P. M. ; Haalck, T. ; Thoms, K.-M. ; Herbschleb, K. ; Leichsenring, J. ; Menzer, A. ; Kopp-Schneider, A. ; Long, G. V. ; Kefford, R. ; Enk, A. ; Blank, C. U. ; Hassel, J. C.
Targeted Therapy in Advanced Melanoma With Rare BRAF Mutations.
Journal of clinical oncology 37(33), 3142-3151 (2019) [10.1200/JCO.19.00489]2019 BibTeX | EndNote: XML, Text | RIS

Gao, X. (First author) ; Xuan, Y. ; Benner, A. ; Anusruti, A. ; Brenner, H. ; Schöttker, B. (Last author)
Nitric Oxide Metabolites and Lung Cancer Incidence: A Matched Case-Control Study Nested in the ESTHER Cohort.
Oxidative medicine and cellular longevity 2019, 6470950 (2019) [10.1155/2019/6470950]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Bhardwaj, M. (First author) ; Gies, A. ; Weigl, K. ; Tikk, K. ; Benner, A. ; Schrotz-King, P. ; Borchers, C. H. ; Brenner, H. (Last author)
Evaluation and Validation of Plasma Proteins Using Two Different Protein Detection Methods for Early Detection of Colorectal Cancer.
Cancers 11(10), 1426 (2019) [10.3390/cancers11101426]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Maier-Hein, L. (First author) ; Eisenmann, M. ; Reinke, A. ; Onogur, S. ; Stankovic, M. ; Scholz, P. ; Arbel, T. ; Bogunovic, H. ; Bradley, A. P. ; Carass, A. ; Feldmann, C. ; Frangi, A. F. ; Full, P. ; van Ginneken, B. ; Hanbury, A. ; Honauer, K. ; Kozubek, M. ; Landman, B. A. ; März, K. ; Maier, O. ; Maier-Hein, K. ; Menze, B. H. ; Müller, H. ; Neher, P. ; Niessen, W. ; Rajpoot, N. ; Sharp, G. C. ; Sirinukunwattana, K. ; Speidel, S. ; Stock, C. ; Stoyanov, D. ; Taha, A. A. ; van der Sommen, F. ; Wang, C.-W. ; Weber, M.-A. ; Zheng, G. ; Jannin, P. ; Kopp-Schneider, A. (Last author)
Author Correction: Why rankings of biomedical image analysis competitions should be interpreted with care.
Nature Communications 10(1), 588 (2019) [10.1038/s41467-019-08563-w]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Tisch, N. ; Freire-Valls, A. ; Yerbes, R. ; Paredes, I. ; La Porta, S. ; Wang, X. ; Martín-Pérez, R. ; Castro, L. ; Wong, W. W. ; Coultas, L. ; Strilic, B. ; Gröne, H.-J. ; Hielscher, T. ; Mogler, C. ; Adams, R. ; Heiduschka, P. ; Claesson-Welsh, L. ; Mazzone, M. ; López-Rivas, A. ; Schmidt, T. ; Augustin, H. G. ; Ruiz de Almodovar, C.
Caspase-8 modulates physiological and pathological angiogenesis during retina development.
The journal of clinical investigation 129(12), 5092-5107 (2019) [10.1172/JCI122767]2019 BibTeX | EndNote: XML, Text | RIS

Heinzl, H. ; Benner, A. (Last author)
Three brief pieces of statistical advice for medical peer reviewers.
European journal of clinical investigation 49(11), e13171 (2019) [10.1111/eci.13171]2019 BibTeX | EndNote: XML, Text | RIS

Zhan, T. ; Hielscher, T. ; Eckardt, M. ; Giese, T. ; Schäfer, C. ; Riemann, J. F. ; Ebert, M. P. ; Belle, S.
The effect of gender-specific invitation letters on utilization of colorectal cancer screening.
Zeitschrift fu?r Gastroenterologie 57(9), 1051-1058 (2019) [10.1055/a-0958-2874 ]2019 BibTeX | EndNote: XML, Text | RIS

Edelmann, D. (First author) ; Fokianos, K. ; Pitsillou, M.
An Updated Literature Review of Distance Correlation and Its Applications to Time Series
International statistical review 87(2), 237 - 262 (2019) [10.1111/insr.12294]2019 BibTeX | EndNote: XML, Text | RIS

Das, K. (First author) ; Eisel, D. ; Vormehr, M. ; Müller-Decker, K. ; Hommertgen, A. ; Jäger, D. ; Zörnig, I. ; Feuerer, M. ; Kopp-Schneider, A. ; Osen, W. ; Eichmüller, S. (Last author)
A transplantable tumor model allowing investigation of NY-BR-1-specific T cell responses in HLA-DRB1*0401 transgenic mice.
BMC cancer 19(1), 914 (2019) [10.1186/s12885-019-6102-6]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Hekler, A. (First author) ; Utikal, J. S. ; Enk, A. H. ; et al
Superior skin cancer classification by the combination of human and artificial intelligence.
European journal of cancer 120, 114 - 121 (2019) [10.1016/j.ejca.2019.07.019]2019 BibTeX | EndNote: XML, Text | RIS

Merz, M. ; Hielscher, T. ; Mai, E. K. ; Seckinger, A. ; Hose, D. ; Jauch, A. ; Sauer, S. ; Luntz, S. ; Bertsch, U. ; Raab, M. S. ; Neben, K. ; Salwender, H. ; Blau, I. W. ; Lindemann, H.-W. ; Dürig, J. ; Scheid, C. ; Haenel, M. ; Weisel, K. ; Weber, T. ; Delorme, S. ; Goldschmidt, H. ; Hillengass, J.
Cystic transformation of focal lesions after therapy is associated with remission but adverse outcome in myeloma.
Blood cancer journal 9(9), 71 (2019) [10.1038/s41408-019-0235-3]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Radtke, J. P. (First author) ; Giganti, F. ; Wiesenfarth, M. ; Stabile, A. ; Marenco, J. ; Orczyk, C. ; Kasivisvanathan, V. ; Nyarangi-Dix, J. N. ; Schütz, V. ; Dieffenbacher, S. ; Görtz, M. ; Stenzinger, A. ; Roth, W. ; Freeman, A. ; Punwani, S. ; Bonekamp, D. ; Schlemmer, H.-P. ; Hohenfellner, M. ; Emberton, M. ; Moore, C. M.
Prediction of significant prostate cancer in biopsy-naïve men: Validation of a novel risk model combining MRI and clinical parameters and comparison to an ERSPC risk calculator and PI-RADS.
PLOS ONE 14(8), e0221350 - (2019) [10.1371/journal.pone.0221350]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Schlenk, R. F. (First author) ; Weber, D. ; Herr, W. ; Wulf, G. ; Salih, H. R. ; Derigs, H. G. ; Kuendgen, A. ; Ringhoffer, M. ; Hertenstein, B. ; Martens, U. M. ; Grießhammer, M. ; Bernhard, H. ; Krauter, J. ; Girschikofsky, M. ; Wolf, D. ; Lange, E. ; Westermann, J. ; Koller, E. ; Kremers, S. ; Wattad, M. ; Heuser, M. ; Thol, F. ; Göhring, G. ; Haase, D. ; Teleanu, V. ; Gaidzik, V. ; Benner, A. ; Döhner, K. ; Ganser, A. ; Paschka, P. ; Döhner, H.
Randomized phase-II trial evaluating induction therapy with idarubicin and etoposide plus sequential or concurrent azacitidine and maintenance therapy with azacitidine.
Leukemia 33(8), 1923 - 1933 (2019) [10.1038/s41375-019-0395-y]2019 BibTeX | EndNote: XML, Text | RIS

Maron, R. C. (First author) ; Weichenthal, M. ; Utikal, J. S. ; et al
Systematic outperformance of 112 dermatologists in multiclass skin cancer image classification by convolutional neural networks.
European journal of cancer 119, 57 - 65 (2019) [10.1016/j.ejca.2019.06.013]2019 BibTeX | EndNote: XML, Text | RIS

Röhrich, M. (First author) ; Loktev, A. (First author) ; Wefers, A. K. ; Altmann, A. ; Paech, D. ; Adeberg, S. ; Windisch, P. ; Hielscher, T. ; Flechsig, P. ; Floca, R. ; Leitz, D. ; Schuster, J. P. ; Huber, P. E. ; Debus, J. ; von Deimling, A. ; Lindner, T. (Last author) ; Haberkorn, U. (Last author)
IDH-wildtype glioblastomas and grade III/IV IDH-mutant gliomas show elevated tracer uptake in fibroblast activation protein-specific PET/CT.
European journal of nuclear medicine and molecular imaging 46(12), 2569-2580 (2019) [10.1007/s00259-019-04444-y]2019 BibTeX | EndNote: XML, Text | RIS

Brinker, T. J. (First author) ; Hekler, A. ; Enk, A. H. ; Berking, C. ; Haferkamp, S. ; Hauschild, A. ; Weichenthal, M. ; Klode, J. ; Schadendorf, D. ; Holland-Letz, T. ; von Kalle, C. ; Fröhling, S. ; Schilling, B. ; Utikal, J. (Last author)
Deep neural networks are superior to dermatologists in melanoma image classification.
European journal of cancer 119, 11 - 17 (2019) [10.1016/j.ejca.2019.05.023]2019 BibTeX | EndNote: XML, Text | RIS

Pal, A. (First author) ; Zimmer, P. ; Schmidt, M. E. ; Hummel, M. ; Ulrich, C. M. ; Wiskemann, J. ; Steindorf, K. (Last author)
No Evidence for Effect of Exercise on Transcriptome of NK Cells in Breast Cancer Patients Undergoing Adjuvant Therapy: Results From a Pilot Study
Frontiers in physiology 10, 959 (2019) [10.3389/fphys.2019.00959]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Jia, M. (First author) ; Zhang, Y. ; Jansen, L. ; Walter, V. ; Edelmann, D. ; Gündert, M. ; Tagscherer, K. E. ; Roth, W. ; Bewerunge-Hudler, M. ; Herpel, E. ; Kloor, M. ; Ulrich, A. ; Burwinkel, B. ; Bläker, H. ; Chang-Claude, J. ; Brenner, H. ; Hoffmeister, M. (Last author)
A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival.
Clinical epigenetics 11(1), 109 (2019) [10.1186/s13148-019-0703-4]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Afshar-Oromieh, A. ; Vollnberg, B. ; Alberts, I. ; Bähler, A. ; Sachpekidis, C. ; Dijkstra, L. ; Haupt, F. ; Boxler, S. ; Gross, T. ; Holland-Letz, T. ; Thalmann, G. ; Heverhagen, J. ; Rominger, A. ; Härmä, K. ; Maurer, M. H.
Comparison of PSMA-ligand PET/CT and multiparametric MRI for the detection of recurrent prostate cancer in the pelvis.
European journal of nuclear medicine and molecular imaging 46(11), 2289-2297 (2019) [10.1007/s00259-019-04438-w]2019 BibTeX | EndNote: XML, Text | RIS

Calderazzo, S. (First author) ; Tavel, D. ; Zurich, M.-G. ; Kopp-Schneider, A. (Last author)
Model-based estimation of lowest observed effect concentration from replicate experiments to identify potential biomarkers of in vitro neurotoxicity.
Archives of toxicology 93(9), 2635-2644 (2019) [10.1007/s00204-019-02520-8]2019 BibTeX | EndNote: XML, Text | RIS

Dittrich, T. (First author) ; Benner, A. ; Kimmich, C. ; Siepen, F. A. d. ; Veelken, K. ; Kristen, A. V. ; Bochtler, T. ; Katus, H. A. ; Müller-Tidow, C. ; Hegenbart, U. ; Schönland, S. O.
Performance analysis of AL amyloidosis cardiac biomarker staging systems with special focus on renal failure and atrial arrhythmia.
Haematologica 104(7), 1451 - 1459 (2019) [10.3324/haematol.2018.205336]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Hose, D. ; Beck, S. ; Salwender, H. ; Emde, M. ; Bertsch, U. ; Kunz, C. ; Scheid, C. ; Hänel, M. ; Weisel, K. ; Hielscher, T. ; Raab, M. S. ; Goldschmidt, H. ; Jauch, A. ; Moreaux, J. ; Seckinger, A.
Prospective target assessment and multimodal prediction of survival for personalized and risk-adapted treatment strategies in multiple myeloma in the GMMG-MM5 multicenter trial.
Journal of hematology & oncology 12(1), 65 (2019) [10.1186/s13045-019-0750-5]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Bonekamp, D. (First author) ; Kohl, S. ; Wiesenfarth, M. ; Schelb, P. ; Radtke, J. P. ; Goetz, M. ; Kickingereder, P. ; Yaqubi, K. ; Hitthaler, B. ; Gaehlert, N. ; Kuder, T. A. ; Deister, F. ; Freitag, M. ; Hohenfellner, M. ; Hadaschik, B. A. ; Schlemmer, H.-P. ; Maier-Hein, K. H. (Last author)
Radiomic Machine Learning: Is It Really a Useful Method for the Characterization of Prostate Cancer? Response
Radiology 291(1), 270 - 270 (2019)2019 BibTeX | EndNote: XML, Text | RIS

Sachpekidis, C. (First author) ; Merz, M. ; Kopp-Schneider, A. ; Jauch, A. ; Raab, M.-S. ; Sauer, S. ; Hillengass, J. ; Goldschmidt, H. ; Dimitrakopoulou-Strauss, A. (Last author)
Quantitative dynamic 18F-FDG PET/CT before autologous stem cell transplantation predicts survival in multiple myeloma.
Haematologica 104(9), e420-e423 (2019) [10.3324/haematol.2018.213041]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Hekler, A. (First author) ; Utikal, J. S. ; Enk, A. H. ; Berking, C. ; Klode, J. ; Schadendorf, D. ; Jansen, P. ; Franklin, C. ; Holland-Letz, T. ; Krahl, D. ; von Kalle, C. ; Fröhling, S. ; Brinker, T. J. (Last author)
Pathologist-level classification of histopathological melanoma images with deep neural networks.
European journal of cancer 115, 79 - 83 (2019) [10.1016/j.ejca.2019.04.021]2019 BibTeX | EndNote: XML, Text | RIS

Haffa, M. (First author) ; Lin, T. ; Holowatyj, A. N. ; Kratz, M. ; Toth, R. ; Benner, A. ; Gigic, B. ; Habermann, N. ; Schrotz-King, P. ; Böhm, J. ; Brenner, H. ; Schneider, M. ; Ulrich, A. ; Herpel, E. ; Schirmacher, P. ; Straub, B. K. ; Nattenmüller, J. ; Kauczor, H.-U. ; Ball, C. R. ; Ulrich, C. M. (Last author) ; Glimm, H. (Last author) ; Scherer, D. (Last author)
Transcriptome profiling of adipose tissue reveals depot-specific metabolic alterations among colorectal cancer patients.
The journal of clinical endocrinology & metabolism 104, 5225-5237 (2019) [10.1210/jc.2019-00461]2019 BibTeX | EndNote: XML, Text | RIS

Zgheib, E. ; Limonciel, A. ; Jiang, X. ; Wilmes, A. ; Wink, S. ; van de Water, B. ; Kopp-Schneider, A. ; Bois, F. Y. ; Jennings, P.
Corrigendum: Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases.
Frontiers in genetics 10, 517 (2019) [10.3389/fgene.2019.00517]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Slynko, A. ; Benner, A. (Last author)
Statistical methods for classification of 5hmC levels based on the Illumina Inifinium HumanMethylation450 (450k) array data, under the paired bisulfite (BS) and oxidative bisulfite (oxBS) treatment.
PLOS ONE 14(6), e0218103 - (2019) [10.1371/journal.pone.0218103]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Schulze-Edinghausen, L. (First author) ; Dürr, C. ; Öztürk, S. ; Zucknick, M. ; Benner, A. ; Kalter, V. ; Ohl, S. ; Close, V. ; Wuchter, P. ; Stilgenbauer, S. ; Lichter, P. ; Seiffert, M. (Last author)
Dissecting the Prognostic Significance and Functional Role of Progranulin in Chronic Lymphocytic Leukemia.
Cancers 11(6), 822 (2019) [10.3390/cancers11060822]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Salwender, H. ; Bertsch, U. ; Weisel, K. ; Duerig, J. ; Kunz, C. ; Benner, A. ; Blau, I. W. ; Raab, M. S. ; Hillengass, J. ; Hose, D. ; Huhn, S. ; Hundemer, M. ; Andrulis, M. ; Jauch, A. ; Seidel-Glaetzer, A. ; Lindemann, H.-W. ; Hensel, M. ; Fronhoffs, S. ; Martens, U. ; Hansen, T. ; Wattad, M. ; Graeven, U. ; Munder, M. ; Fenk, R. ; Haenel, M. ; Scheid, C. ; Goldschmidt, H.
Rationale and design of the German-speaking myeloma multicenter group (GMMG) trial HD6: a randomized phase III trial on the effect of elotuzumab in VRD induction/consolidation and lenalidomide maintenance in patients with newly diagnosed myeloma.
BMC cancer 19(1), 504 (2019) [10.1186/s12885-019-5600-x]2019 DBCoverage BibTeX | EndNote: XML, Text | RIS

Muenchau, S. ; Deutsch, R. ; de Castro, I. J. ; Hielscher, T. ; Heber, N. ; Niesler, B. ; Lusic, M. ; Stanifer, M. L. ; Boulant, S. (Last author)
Hypoxic environment promotes barrier formation in human intestinal epithelial cells through regulation of miRNA-320a expression.
Molecular and cellular biology 39(14), e00553-18 (2019) [10.1128/MCB.00553-18]2019 BibTeX | EndNote: XML, Text | RIS

Brenner, H. (First author) ; Calderazzo, S. ; Seufferlein, T. ; Ludwig, L. ; Dikopoulos, N. ; Mangold, J. ; Böck, W. ; Stolz, T. ; Eisenbach, T. ; Block, T. ; Kopp-Schneider, A. ; Czock, D. ; Tikk, K. (Last author)
Effect of a Single Aspirin Dose Prior to Fecal Immunochemical Testing on Test Sensitivity for Detecting Advanced Colorectal Neoplasms: A Randomized Clinical Trial.
The journal of the American Medical Association 321(17), 1686 - 1692 (2019) [10.1001/jama.2019.4755]2019 BibTeX | EndNote: XML, Text | RIS

Weisel, K. C. ; Scheid, C. ; Zago, M. ; Besemer, B. ; Mai, E. K. ; Haenel, M. ; Duerig, J. ; Munder, M. ; Lindemann, H.-W. ; Seckinger, A. ; Kunz, C. ; Benner, A. ; Hose, D. ; Jauch, A. ; Salwender, H. ; Goldschmidt, H.
Addition of cyclophosphamide on insufficient response to pomalidomide and dexamethasone: results of the phase II PERSPECTIVE Multiple Myeloma trial.
Blood cancer journal 9(4), 45 (2019) [10.1038/s41408-019-0206-8]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Brinker, T. J. (First author) ; Hekler, A. ; Enk, A. H. ; et al
Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task.
European journal of cancer 113, 47 - 54 (2019) [10.1016/j.ejca.2019.04.001]2019 BibTeX | EndNote: XML, Text | RIS

Delacher, M. (First author) ; Schmidl, C. ; Herzig, Y. ; Breloer, M. ; Hartmann, W. ; Brunk, F. ; Kägebein, D. ; Träger, U. ; Hofer, A.-C. ; Bittner, S. ; Weichenhan, D. ; Imbusch, C. D. ; Hotz-Wagenblatt, A. ; Hielscher, T. ; Breiling, A. ; Federico, G. ; Gröne, H.-J. ; Schmid, R. M. ; Rehli, M. ; Abramson, J. ; Feuerer, M. (Last author)
Rbpj expression in regulatory T cells is critical for restraining TH2 responses.
Nature Communications 10(1), 1621 (2019) [10.1038/s41467-019-09276-w]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Srinivas, N. (First author) ; Rachakonda, S. ; Hielscher, T. ; Calderazzo, S. ; Rudnai, P. ; Gurzau, E. ; Koppova, K. ; Fletcher, T. ; Kumar, R. (Last author)
Telomere length, arsenic exposure and risk of basal cell carcinoma of skin.
Carcinogenesis 40(6), 715-723 (2019) [10.1093/carcin/bgz059]2019 BibTeX | EndNote: XML, Text | RIS

Bonsack, M. (First author) ; Hoppe, S. (First author) ; Winter, J. ; Tichy, D. ; Zeller, C. ; Küpper, M. ; Schitter, E. C. ; Blatnik, R. ; Riemer, A. (Last author)
Performance evaluation of MHC class-I binding prediction tools based on an experimentally validated MHC-peptide binding dataset.
Cancer immunology research 7(5), 719-736 (2019) [10.1158/2326-6066.CIR-18-0584]2019 BibTeX | EndNote: XML, Text | RIS

Neumeyer, S. M. (First author) ; Popanda, O. ; Edelmann, D. ; Butterbach, K. ; Toth, C. ; Roth, W. ; Bläker, H. ; Jiang, R. ; Herpel, E. ; Jäkel, C. ; Schmezer, P. ; Jansen, L. ; Alwers, E. ; Benner, A. ; Burwinkel, B. ; Hoffmeister, M. ; Brenner, H. ; Chang-Claude, J. (Last author)
Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancer.
Epigenetics 14(5), 477-493 (2019) [10.1080/15592294.2019.1595998]2019 BibTeX | EndNote: XML, Text | RIS

Kraft, B. (First author) ; Lombard, J. ; Kirsch, M. ; Wuchter, P. ; Bugert, P. ; Hielscher, T. ; Blank, N. ; Krämer, A. (Last author)
SMC3 protein levels impact on karyotype and outcome in acute myeloid leukemia.
Leukemia 33(3), 795 - 799 (2019) [10.1038/s41375-018-0287-6]2019 BibTeX | EndNote: XML, Text | RIS

Buhl, J. L. (First author) ; Selt, F. ; Hielscher, T. ; Guiho, R. ; Ecker, J. ; Sahm, F. ; Ridinger, J. ; Riehl, D. ; Usta, D. ; Ismer, B. ; Sommerkamp, A. C. ; Martinez-Barbera, J. P. ; Wefers, A. K. ; Remke, M. ; Picard, D. ; Pusch, S. ; Gronych, J. ; Oehme, I. ; van Tilburg, C. M. ; Kool, M. ; Kuhn, D. ; Capper, D. ; von Deimling, A. ; Schuhmann, M. U. ; Herold-Mende, C. ; Korshunov, A. ; Brummer, T. ; Pfister, S. ; Jones, D. ; Witt, O. ; Milde, T. (Last author)
The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma.
Clinical cancer research 25(6), 1851 - 1866 (2019) [10.1158/1078-0432.CCR-18-1965]2019 BibTeX | EndNote: XML, Text | RIS

Krilaviciute, A. (First author) ; Leja, M. ; Kopp-Schneider, A. ; Barash, O. ; Khatib, S. ; Amal, H. ; Broza, Y. Y. ; Polaka, I. ; Parshutin, S. ; Rudule, A. ; Haick, H. ; Brenner, H. (Last author)
Associations of diet and lifestyle factors with common volatile organic compounds in exhaled breath of average-risk individuals.
Journal of breath research 13(2), 026006 (2019) [10.1088/1752-7163/aaf3dc]2019 BibTeX | EndNote: XML, Text | RIS

Schlenk, R. ; Weber, D. ; Fiedler, W. ; Salih, H. R. ; Wulf, G. ; Salwender, H. ; Schroeder, T. ; Kindler, T. ; Lübbert, M. ; Wolf, D. ; Westermann, J. ; Kraemer, D. ; Götze, K. S. ; Horst, H.-A. ; Krauter, J. ; Girschikofsky, M. ; Ringhoffer, M. ; Südhoff, T. ; Held, G. ; Derigs, H.-G. ; Schroers, R. ; Greil, R. ; Grießhammer, M. ; Lange, E. ; Burchardt, A. ; Martens, U. ; Hertenstein, B. ; Marretta, L. ; Heuser, M. ; Thol, F. ; Gaidzik, V. I. ; Herr, W. ; Krzykalla, J. ; Benner, A. ; Döhner, K. ; Ganser, A. ; Paschka, P. ; Döhner, H. ; Group, G. A. S. (Collaboration Author)
Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD.
Blood 133(8), 840 - 851 (2019) [10.1182/blood-2018-08-869453]2019 BibTeX | EndNote: XML, Text | RIS

Korshunov, A. (First author) ; Casalini, B. ; Chavez, L. ; Hielscher, T. ; Sill, M. ; Ryzhova, M. ; Sharma, T. ; Schrimpf, D. ; Stichel, D. ; Capper, D. ; Reuss, D. E. ; Sturm, D. ; Absalyamova, O. ; Golanov, A. ; Lambo, S. ; Bewerunge-Hudler, M. ; Lichter, P. ; Herold-Mende, C. ; Wick, W. ; Pfister, S. ; Kool, M. ; Jones, D. ; von Deimling, A. ; Sahm, F. (Last author)
Integrated molecular characterization of IDH-mutant glioblastomas.
Neuropathology & applied neurobiology 45(2), 108 - 118 (2019) [10.1111/nan.12523]2019 BibTeX | EndNote: XML, Text | RIS

Sachpekidis, C. (First author) ; Kopp-Schneider, A. ; Hakim-Meibodi, L. ; Dimitrakopoulou-Strauss, A. (Last author) ; Hassel, J. C.
18F-FDG PET/CT longitudinal studies in patients with advanced metastatic melanoma for response evaluation of combination treatment with vemurafenib and ipilimumab.
Melanoma research 29(2), 178 - 186 (2019) [10.1097/CMR.0000000000000541]2019 BibTeX | EndNote: XML, Text | RIS

Kriegsmann, K. ; Baertsch, M.-A. ; Awwad, M. H. S. ; Merz, M. ; Hose, D. ; Seckinger, A. ; Jauch, A. ; Becker, N. ; Benner, A. ; Raab, M. S. ; Hillengass, J. ; Bertsch, U. ; Dürig, J. ; Salwender, H. J. ; Hänel, M. ; Fenk, R. ; Munder, M. ; Weisel, K. ; Müller-Tidow, C. ; Goldschmidt, H. ; Hundemer, M.
Cereblon-binding proteins expression levels correlate with hyperdiploidy in newly diagnosed multiple myeloma patients.
Blood cancer journal 9(2), 13 (2019) [10.1038/s41408-019-0174-z]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Maatouk, I. ; He, S. ; Hummel, M. ; Hemmer, S. ; Hillengass, M. ; Goldschmidt, H. ; Hartmann, M. ; Herzog, W. ; Hillengass, J.
Patients with precursor disease exhibit similar psychological distress and mental HRQOL as patients with active myeloma.
Blood cancer journal 9(2), 9 (2019) [10.1038/s41408-019-0172-1]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Jobst, B. J. ; Owsijewitsch, M. ; Kauczor, H.-U. ; Biederer, J. ; Ley, S. ; Becker, N. ; Kopp-Schneider, A. ; Delorme, S. ; Heussel, C. P. ; Puderbach, M. ; Wielpütz, M. O. ; Ley-Zaporozhan, J.
GOLD stage predicts thoracic aortic calcifications in patients with COPD.
Experimental and Therapeutic Medicine 17(1), 967-973 (2019) [10.3892/etm.2018.7039]2019 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Flechsig, P. ; Zabeck, H. ; Reubold, S. ; Sachpekidis, C. ; Rathke, H. ; Röhrich, M. ; Holland-Letz, T. ; Heussel, C.-P. ; Harms, A. ; Kauczor, H.-U. ; Haberkorn, U. ; Giesel, F. (Last author)
Impact of FDG-PET and Dynamic Contrast-Enhanced MRI in Comparison with DWI for N-Staging in Lung Cancer Patients
Iranian journal of radiology 16(1), e68638 (2019) [10.5812/iranjradiol.68638]2019 BibTeX | EndNote: XML, Text | RIS

Gündert, M. (First author) ; Edelmann, D. ; Benner, A. ; Jansen, L. ; Jia, M. ; Walter, V. ; Knebel, P. ; Herpel, E. ; Chang-Claude, J. ; Hoffmeister, M. ; Brenner, H. ; Burwinkel, B. (Last author)
Genome-wide DNA methylation analysis reveals a prognostic classifier for non-metastatic colorectal cancer (ProMCol classifier).
Gut 68(1), 101 - 110 (2019) [10.1136/gutjnl-2017-314711]2019 BibTeX | EndNote: XML, Text | RIS

Sachpekidis, C. (First author) ; Larribère, L. ; Kopp-Schneider, A. ; Hassel, J. C. ; Dimitrakopoulou-Strauss, A. (Last author)
Can benign lymphoid tissue changes in 18F-FDG PET/CT predict response to immunotherapy in metastatic melanoma?315
Cancer immunology immunotherapy 68(2), 297-303 (2019) [10.1007/s00262-018-2279-9]2019 BibTeX | EndNote: XML, Text | RIS

Koerber, S. A. ; Seither, B. ; Slynko, A. ; Haefner, M. F. ; Krug, D. ; Liermann, J. ; Adeberg, S. ; Herfarth, K. ; Debus, J. ; Sterzing, F.
Chemoradiation in female patients with anal cancer: Patient-reported outcome of acute and chronic side effects.
Tumori journal 105(2), 174-180 (2019) [10.1177/0300891618811273]2019 BibTeX | EndNote: XML, Text | RIS

Bochtler, T. (First author) ; Kartal-Kaess, M. ; Granzow, M. ; Hielscher, T. ; Cosenza, M. R. ; Herold-Mende, C. ; Jauch, A. ; Krämer, A. (Last author)
Micronucleus formation in human cancer cells is biased by chromosome size.
Genes, chromosomes & cancer 58(6), 392-395 (2019) [10.1002/gcc.22707]2019 BibTeX | EndNote: XML, Text | RIS

Prutsch, N. ; Gurnhofer, E. ; Suske, T. ; Liang, H. C. ; Schlederer, M. ; Roos, S. ; Wu, L. C. ; Simonitsch-Klupp, I. ; Alvarez-Hernandez, A. ; Kornauth, C. ; Leone, D. A. ; Svinka, J. ; Eferl, R. ; Limberger, T. ; Aufinger, A. ; Shirsath, N. ; Wolf, P. ; Hielscher, T. ; Aberger, F. ; Schmoellerl, J. ; Stoiber, D. ; Strobl, B. ; Jäger, U. ; Staber, P. B. ; Grebien, F. ; Moriggl, R. ; Müller, M. ; Inghirami, G. G. ; Sanda, T. ; Look, A. T. ; Turner, S. D. ; Kenner, L. ; Merkel, O.
Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.
Leukemia 33(3), 696-709 (2019) [10.1038/s41375-018-0239-1]2019 BibTeX | EndNote: XML, Text | RIS

Mai, E. K. ; Hielscher, T. ; Bertsch, U. ; Schlenzka, J. ; Salwender, H. J. ; Munder, M. ; Gerecke, C. ; Dührsen, U. ; Brossart, P. ; Neben, K. ; Hillengass, J. ; Raab, M. S. ; Merz, M. ; Baertsch, M.-A. ; Jauch, A. ; Hose, D. ; Martin, H. ; Lindemann, H.-W. ; Blau, I. W. ; Scheid, C. ; Weisel, K. C. ; Goldschmidt, H. ; Group, G. M. M. (Collaboration Author)
Bortezomib-based induction therapy with high or low-dose dexamethasone in newly diagnosed, transplant-eligible multiple myeloma.
Leukemia 33(1), 258-261 (2019) [10.1038/s41375-018-0195-9]2019 BibTeX | EndNote: XML, Text | RIS

Koerber, S. A. (First author) ; Will, L. ; Kratochwil, C. ; Haefner, M. F. ; Rathke, H. ; Kremer, C. ; Merkle, J. ; Herfarth, K. ; Kopka, K. ; Choyke, P. L. ; Holland-Letz, T. ; Haberkorn, U. ; Debus, J. ; Giesel, F. (Last author)
68Ga-PSMA-11 PET/CT in Primary and Recurrent Prostate Carcinoma: Implications for Radiotherapeutic Management in 121 Patients.
Journal of nuclear medicine 60(2), 234-240 (2019) [10.2967/jnumed.118.211086]2019 BibTeX | EndNote: XML, Text | RIS

Abukiwan, A. ; Nwaeburu, C. C. ; Bauer, N. ; Zhao, Z. ; Liu, L. ; Gladkich, J. ; Gross, W. ; Benner, A. ; Strobel, O. ; Fellenberg, J. ; Herr, I.
Dexamethasone-induced inhibition of miR-132 via methylation promotes TGF-?-driven progression of pancreatic cancer.
International journal of oncology 54(1), 53-64 (2019) [10.3892/ijo.2018.4616]2019 BibTeX | EndNote: XML, Text | RIS

von Hagens, C. ; Walter-Sack, I. ; Goeckenjan, M. ; Storch-Hagenlocher, B. ; Sertel, S. ; Elsässer, M. ; Remppis, B. A. ; Munzinger, J. ; Edler, L. ; Efferth, T. ; Schneeweiss, A. ; Strowitzki, T.
Long-term add-on therapy (compassionate use) with oral artesunate in patients with metastatic breast cancer after participating in a phase I study (ARTIC M33/2)
Phytomedicine 54, 140 - 148 (2019) [10.1016/j.phymed.2018.09.178]2019 BibTeX | EndNote: XML, Text | RIS

Bonekamp, D. (First author) ; Schelb, P. ; Wiesenfarth, M. ; Kuder, T. A. ; Deister, F. ; Stenzinger, A. ; Nyarangi-Dix, J. ; Röthke, M. ; Hohenfellner, M. ; Schlemmer, H.-P. ; Radtke, J. P. (Last author)
Histopathological to multiparametric MRI spatial mapping of extended systematic sextant and MR/TRUS-fusion-targeted biopsy of the prostate.
European radiology 29(4), 1820-1830 (2019) [10.1007/s00330-018-5751-1]2019 BibTeX | EndNote: XML, Text | RIS

Berberich, A. (First author) ; Kessler, T. ; Thome, C. ; Pusch, S. ; Hielscher, T. ; Sahm, F. ; Oezen, I. ; Schmitt, L.-M. ; Ciprut, S. ; Hucke, N. ; Rübmann, P. ; Fischer, M. ; Lemke, D. ; Breckwoldt, M. ; von Deimling, A. ; Bendszus, M. ; Platten, M. ; Wick, W. (Last author)
Targeting resistance against the MDM2 inhibitor RG7388 in glioblastoma cells by the MEK inhibitor trametinib.
Clinical cancer research 25(1), 253-265 (2019) [10.1158/1078-0432.CCR-18-1580]2019 BibTeX | EndNote: XML, Text | RIS

Calderazzo, S. (First author) ; Brancaccio, M. ; Finkenstädt, B.
Filtering and Inference for stochastic oscillators with distributed delays.
Bioinformatics 144(6), 1275-1283 (2019) [10.1093/bioinformatics/bty782]2019 BibTeX | EndNote: XML, Text | RIS

Lorenz, N. ; Dänicke, S. ; Edler, L. ; Gottschalk, C. ; Lassek, E. ; Marko, D. ; Rychlik, M. ; Mally, A.
A critical evaluation of health risk assessment of modified mycotoxins with a special focus on zearalenone.
Mycotoxin research 35(1), 27-46 (2019) [10.1007/s12550-018-0328-z]2019 BibTeX | EndNote: XML, Text | RIS

Kopp-Schneider, A. (First author) ; Wiesenfarth, M. ; Witt, R. ; Edelmann, D. ; Witt, O. ; Abel, U.
Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions-A calibration approach.
Biometrical journal 61(3), 488-502 (2019) [10.1002/bimj.201700209]2019 BibTeX | EndNote: XML, Text | RIS

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