Publications 2017

Afshar-Oromieh A., Holland-Letz T., Giesel F.L., Kratochwil C., Mier W., Haufe S., Debus N., Eder M., Eisenhut M., Schäfer M., Neels O., Hohenfellner M., Kopka K., Kauczor H.U., Debus J., Haberkorn U.: Diagnostic performance of 68Ga-PSMA-11 (HBED-CC) PET/CT in patients with recurrent prostate cancer: evaluation in 1007 patients. Eur.J.Nucl.Med.Mol.Imag. 44 (8) 1258-1268, 2017.

Afshar-Oromieh A., Haberkorn U., Zechmann C., Armor T., Mier W., Spohn F., Debus N., Holland-Letz T., Babich J., Kratochwil C.: Repeated PSMA-targeting radioligand therapy of metastatic prostate cancer with 131I-MIP-1095. Eur.J.Nucl.Med.Mol.Imag. 44 (6) 950-959, 2017.

Afshar-Oromieh A., Sattler L.P., Mier W., Hadaschik B.A., Debus J., Holland-Letz T., Kopka K., Haberkorn U.: The clinical impact of additional late PET/CT imaging with 68Ga-PSMA-11 (HBED-CC) in the diagnosis of prostate cancer. J.Nucl.Med. 58 (5) 750-755, 2017.

Bärtsch M.A., Schlenzka J., Lisenko K., Krzykalla J., Becker N., Weisel K., Noppeney R., Martin H., Lindemann H.W., Hänel M., Nogai A., Scheid C., Salwender H., Fenk R., Graeven U., Reimer P., Schmidt-Hieber M., Görner M., Schmidt-Wolf I.G.H., Klein S., Ho A.D., Goldschmidt H., Wuchter P.: Cyclophosphamide-based stem cell mobilization in relapsed multiple myeloma patients: A subgroup analysis from the phase III trial ReLApsE. Eur.J.Haematol. 99 (1) 42-50, 2017.

Beisel C., Benner A., Kunz C., Kopp-Schneider A.: Heterogeneous treatment effects in stratified clinical trials with time-to-event endpoints. Biometr.J. 59 (3) 511-530, 2017.

Berghoff A.S., Wolpert F., Holland-Letz T., Koller R., Widhalm G., Gatterbauer B., Dieckman K., Birner P., Bartsch R., Zielinski C.C., Weller M., Preusser M.: Combining standard clinical blood values for improving survival prediction in patients with newly diagnosed brain metastases-development and validation of the LabBM score. Neuro-Oncol. 19 (9) 1255-1262, 2017.

Bickelhaupt S., Paech D., Laun F.B., Steudle F., Kuder T.A., Mlynarska A., Bach M., Lederer W., Teiner S., Schneider S., Ladd M.E., Daniel H., Stieber A., Kopp-Schneider A., Delorme S., Schlemmer H.P.: Maximum intensity breast diffusion MRI for BI-RADS 4 lesions detected on X-ray mammography. Clin.Radiol. 72 (10) 900.e1-900.e8, 2017.

Bickelhaupt S., Paech D., Kickingereder P., Steudle F., Lederer W., Daniel H., Götz M., Gählert N., Tichy D., Wiesenfarth M., Laun F.B., Maier-Hein K.H., Schlemmer H.P., Bonekamp D.: Prediction of malignancy by a radiomic signature from contrast agent-free diffusion MRI in suspicious breast lesions found on screening mammography. J.Magnet.Resonan.Imag. 46 (2) 604-616, 2017.

Bingel C., Koeneke E., Ridinger J., Bittmann A., Sill M., Peterziel H., Wrobel J.K., Rettig I., Milde T., Fernekorn U., Weise E., Schober A., Witt O., Öhme I.: Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance. Cell Death Dis. 8 (8) e3013, 2017.

Bochtler T., Granzow M., Stölzel F., Kunz C., Mohr B., Kartal-Kaess M., Hinderhofer K., Heilig C.E., Kramer M., Thiede C., Endris V., Kirchner M., Stenzinger A., Benner A., Bornhäuser M., Ehninger G., Ho A.D., Jauch A., Krämer A., Study Alliance Leukemia Investigators: Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia. Blood 129 (10) 1333-1342, 2017.

Breckwoldt M.O., Gradl J., Hähnel S., Hielscher T., Wildemann B., Diem R., Platten M., Wick W., Heiland S., Bendszus M.: Increasing the sensitivity of MRI for the detection of multiple sclerosis lesions by long axial coverage of the spinal cord: a prospective study in 119 patients. J.Neurol. 264 (2) 341-349, 2017.

Brunk F., Michel C., Holland-Letz T., Slynko A., Kopp-Schneider A., Kyewski B., Pinto S.: Dissecting and modeling the emergent murine TEC compartment during ontogeny. Eur.J.Immunol. 47 (7) 1153-1159, 2017.

Cosenza M.R., Cazzola M., Rossberg A., Schieber N.L., Konotop G., Bausch E., Slynko A., Holland-Letz T., Raab M.S., Dubash T., Glimm H., Poppelreuther S., Herold-Mende C., Schwab Y., Krämer A.: Asymmetric centriole numbers at spindle poles cause chromosome missegregation in cancer. Cell Rep. 20 (8) 1906-1920, 2017.

Dittrich C., Bochtler T., Kimmich C., Becker N., Jauch A., Goldschmidt H., Ho A.D., Hegenbart U., Schönland S.O.: AL amyloidosis patients with low amyloidogenic free light chain levels at first diagnosis have an excellent prognosis. Blood 130 (5) 632-642, 2017.

Dueck J., Edelmann D., Richards D.: Distance correlation coefficients for Lancaster distributions. J.Multivar.Anal. 154 19-39, 2017.

Frölich M., Huber M., Wiesenfarth M.: The finite sample performance of semi- and nonparametric estimators for treatment effects and policy evaluation. Comput.Statist.Data Anal. 115 91-102, 2017.

Giesel F., Schneider F., Kratochwil C., Rath D., Holland-Letz T., Moltz J., Kauczor H.U., Schwartz L., Haberkorn U., Flechsig P.: Correlation between SUVmax and CT radiomic analysis using lymph node density in PET/CT-based lymph node staging. J.Nucl.Med. 58 (2) 282-287, 2017.

Göppert B., Rössler S., Becker N., Zucknick M., Vogel M., Warth A., Pathil-Warth A., Mehrabi A., Schirmacher P., Mollenhauer J., Renner M.: DMBT1 expression in biliary carcinogenesis with correlation of clinicopathological data. Histopathol. 70 (7) 1064-1071, 2017.

Gross J.P., Nattenmüller J., Hemmer S., Tichy D., Krzykalla J., Goldschmidt H., Bertsch U., Delorme S., Kauczor H.U., Hillengass J., Merz M.: Body fat composition as predictive factor for treatment response in patients with newly diagnosed multiple myeloma - subgroup analysis of the prospective GMMG MM5 trial. Oncotarget 8 (40) 68460-68471, 2017.

Gündert M., Edelmann D., Benner A., Jansen L., Jia M., Walter V., Knebel P., Herpel E., Chang-Claude J., Hoffmeister M., Brenner A., Burwinkel B.: Genome-wide DNA methylation analysis reveals a prognostic classifier for non-metastatic colorectal cancer (ProMCol classifier). Gut (epub) , 2017.

Haderk F., Schulz R., Iskar M., Cid L.L., Worst T., Willmund K.V., Schulz A., Warnken U., Seiler J., Benner A., Nessling M., Zenz T., Göbel M., Dürig J., Diederichs S., Paggetti J., Moussay E., Stilgenbauer S., Zapatka M., Lichter P., Seiffert M.: Tumor-derived exosomes modulate PD-L1 expression in monocytes. Sci.Immunol. 2 (13) eaah5509, 2017.

Hagens C.v., Walter-Sack I., Göckenjahn M., Osburg J., Storch-Hagenlocher B., Sertel S., Elsässer M., Remppis B.A., Edler L., Munzinger J., Efferth T., Schneeweiss A., Strowitzki T.: Prospective open uncontrolled phase I study to define a well-tolerated dose of oral artesunate as add-on therapy in patients with metastatic breast cancer (ARTIC M33/2). Breast Cancer Res.Treat. 164 (2) 359-369, 2017.

Hegenbart U., Bochtler T., Benner A., Becker N., Kimmich C., Kristen A.V., Beimler J., Hund E., Zorn M., Freiberger A., Gawlik M., Goldschmidt H., Hose D., Jauch A., Ho A.D., Schönland S.O.: Lenalidomide/melphalan/dexamethasone in newly diagnosed patients with immunoglobulin light chain amyloidosis: results of a prospective phase 2 study with long-term follow up. Haematologica 102 (8) 1424-1431, 2017.

Hillengass J., Moulopoulos L.A., Delorme S., Koutoulidis V., Mosebach J., Hielscher T., Drake M., Rajkumar S.V., Oestergaard B., Abildgaard N., Hinge M., Plesner T., Suehara Y., Matsue K., Withofs N., Caers J., Waage A., Goldschmidt H., Dimopoulos M.A., Lentzsch S., Durie B., Terpos E.: Whole-body computed tomography versus conventional skeletal survey in patients with multiple myeloma: a study of the International Myeloma Working Group. Blood Cancer J. 7 (8) e599, 2017.

Holland-Letz T.: On the combination of c- and D-optimal designs: General approaches and applications in dose-response studies. Biometrics 73 (1) 206-213, 2017.

Holland-Letz T., Gunkel N., Amtmann E., Kopp-Schneider A.: Parametric modeling and optimal experimental designs for estimating isobolograms for drug interactions in toxicology. J.Biopharm.Stat. (epub) , 2017.

Holland-Letz T., Kopp-Schneider A.: Optimal experimental designs for estimating the drug combination index in toxicology. Comput.Statist.Data Anal. 117 (182) 193, 2017.

Holzinger D., Wichmann G., Baboci L., Michel A., Höfler D., Wiesenfarth M., Schröder L., Boscolo-Rizzo P., Herold-Mende C., Dyckhoff G., Böhm A., Del Mistro A., Bosch F.X., Dietz A., Pawlita M., Waterboer T.: Sensitivity and specificity of antibodies against HPV16 E6 and other early proteins for the detection of HPV16-driven oropharyngeal squamous cell carcinoma. Int.J.Cancer 140 (12) 2748-2757, 2017.

Huhn S., Weinhold N., Nickel J., Pritsch M., Hielscher T., Hummel M., Bertsch U., Hügle-Dörr B., Vogel M., Angermund R., Hanel M., Salwender H., Weisel K., Durig J., Görner M., Kirchner H., Peter N., Graeven U., Lordick F., Hoffmann M., Reimer P., Blau I.W., Jauch A., Dembowsky K., Möhler T., Wuchter P., Goldschmidt H.: Circulating tumor cells as a biomarker for response to therapy in multiple myeloma patients treated within the GMMG-MM5 trial. Bone Marrow Transplant. 52 (8) 1194-1198, 2017.

Hummel M., Edelmann D., Kopp-Schneider A.: Clustering of samples and variables with mixed-type data. PLoS_ONE 12 (11) e0188274, 2017.

Jaramillo S., Benner A., Krauter J., Martin H., Kindler T., Bentz M., Salih H.R., Held G., Kohne C.H., Gotze K., Lubbert M., Kundgen A., Brossart P., Wattad M., Salwender H., Hertenstein B., Nachbaur D., Wulf G., Horst H.A., Kirchen H., Fiedler W., Raghavachar A., Kremers S., Koller E., Runde V., Heil G., Weber D., Göhring G., Döhner K., Ganser A., Döhner H., Schlenk R.F.: Condensed versus standard schedule of high-dose cytarabine consolidation therapy with pegfilgrastim growth factor support in acute myeloid leukemia. Blood Cancer J. 7 (5) e564, 2017.

Jennemann R., Frederico G., Mathow D., Rabionet M., Rampoldi F., Popovic Z.V., Volz M., Hielscher T., Sandhoff R., Gröne H.J.: Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis. Oncotarget 8 (65) 109201-109216, 2017.

Jiang X., Wink S., van de Water B., Kopp-Schneider A.: Functional analysis of high-content highthroughput imaging data. J.Appl.Statist. 44 (11) 1903-1919, 2017.

Kayser S., Feszler M., Krzykalla J., Schick M., Kramer M., Benner A., Thol F., Platzbecker U., Müller-Tidow C., Ho A.D., Ehninger G., Heuser M., Schlenk R.F., Thiede C., Röllig C., Krämer A.: Clinical impact of KMT2C and SPRY4 expression levels in intensively treated younger adult acute myeloid leukemia patients. Eur.J.Haematol. 99 (6) 544-552, 2017.

Kayser S., Krzykalla J., Elliot M.A., Norsworthy K., Gonzales P., Hills R.K., Baer M.R., Racil Z., Mayer J., Novak J., Zak P., Szotkowski T., Grimwade D., Russell N.H., Walter R.B., Estey E.H., Westermann J., Görner M., Benner A., Krämer A., Smith B.D., Burnett A.K., Thiede C., Röllig C., Ho A.D., Ehninger G., Schlenk R.F., Tallman M.S., Levis M.J., Platzbecker U.: Characteristics and outcome of patients with therapy-related acute promyelocytic leukemia front-line treated with or without arsenic trioxide. Leukem. 31 (11) 2347-2354, 2017.

Kesch C., Vinsensia M., Radtke J.P., Schlemmer H.P., Heller M., Ellert E., Holland-Letz T., Dünsing S., Grabe N., Afshar-Oromieh A., Wieczorek K., Schäfer M., Neels O.C., Cardinale J., Kratochwil C., Hohenfellner M., Kopka K., Haberkorn U., Hadaschik B.A., Giesel F.L.: Intra-individual comparison of 18F-PSMA-1007-PET/CT, multi-parametric MRI and radical prostatectomy specimen in patients with primary prostate cancer - a retrospective, proof of concept study. J.Nucl.Med. 58 (11) 1805-1810, 2017.

Kischkel F.C., Eich J., Meyer C.I., Weidemüller P., Krapfl J., Yassin-Kelepir R., Job L., Fraefel M., Braicu I., Kopp-Schneider A., Sehouli J., de Wilde R.L.: New in vitro system to predict chemotherapeutic efficacy of drug combinations in fresh tumor samples. PeerJ 5 (e3030) , 2017.

Kischkel F.C., Meyer C., Eich J., Nassir M., Mentze M., Braicu I., Kopp-Schneider A., Sehouli J.: Prediction of clinical response to drugs in ovarian cancer using the chemotherapy resistance test (CTR-test). J.Ovar.Res. 10 (1) 72, 2017.

Kölsche C., Schrimpf D., Tharun L., Roth E., Sturm D., Jones D.T.W., Renker E.K., Sill M., Baude A., Sahm F., Capper D., Bewerunge-Hudler M., Hartmann W., Kulozik A.E., Petersen I., Flucke U., Schreuder H.W.B., Büttner R., Weber M.A., Schirmacher P., Plass C., Pfister S.M., von Deimling A., Mechtersheimer G.: Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases. Clin.Sarcoma Res. 7 (9) , 2017.

Laudato S., Patil N., Abba M.L., Leupold J.H., Benner A., Gaiser T., Marx A., Allgayer H.: P53-induced miR-30e-5p inhibits colorectal cancer invasion and metastasis by targeting ITGA6 and ITGB1. Int.J.Cancer 141 (9) 1879-1890, 2017.

Lehners N., Kraemer I., Saadati M., Benner A., Ho A.D., Witzens-Harig M.: Analysis of prognostic factors in patients with newly diagnosed diffuse large B-cell lymphoma and skeletal involvement. BMC Cancer 17 (1) 128, 2017.

Liebers N., Holland-Letz T., Welschof M., Hogset A., Jäger D., Arndt M.A.E., Krauss J.: Highly efficient destruction of squamous carcinoma cells of the head and neck by photochemical internalization of Ranpirnase. J.Exp.Ther.Oncol. 12 (2) 113-120, 2017.

Lipka D., Witte T., Toth R., Yang J., Wiesenfarth M., Nöllke P., Fischer A., Brocks D., Gu Z., Park J., Strahm B., Wlodarski M., Yoshimi A., Claus R., Lübbert M., Busch H., Boerries M., Hartmann M., Schönung M., Kilik U., Langstein J., Wierzbinska J., Pabst C., Garg S., Catala A., De Moerloose B., Dworzak M., Hasle H., Locatelli F., Masetti R., Schmugge M., Smith O., Stary J., Ussowicz M., van den Heuvel-Eibrink M., Assenov Y., Schlesner M., Niemeyer C., Flotho C., Plass C.: RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia. Nat.Commun. (epub) , 2017.

Lisenko K., Wuchter P., Hansberg M., Mangatter A., Benner A., Ho A.D., Goldschmidt H., Hegenbart U., Schönland S.: Comparison of different stem cell mobilization regimens in AL amyloidosis patients. Biol.Blood Marrow Transplant. 23 (11) 1870-1878, 2017.

Luft T., Benner A., Jodele S., Dandoy C.E., Storb R., Gooley T., Sandmaier B.M., Becker N., Radujkovic A., Dreger P., Penack O.: EASIX in patients with acute graft-versus-host disease: a retrospective cohort analysis. Lancet Haematol. 4 (9) e414-e423, 2017.

Maier-Hein K.H., Neher P.F., Houde J.C., Cote M.A., Garyfallidis E., Zhong J., Chamberland M., Yeh F.C., Lin Y.C., Ji Q., Reddick W.E., Glass J.O., Chen D.Q., Feng Y., Gao C., Wu Y., Ma J., Renjie H., Li Q., Westin C.F., Deslauriers-Gauthier S., Gonzalez J.O.O., Paquette M., St-Jean S., Girard G., Rheault F., Sidhu J., Tax C.M.W., Guo F., Mesri H.Y., David S., Froeling M., Heemskerk A.M., Leemans A., Bore A., Pinsard B., Bedetti C., Desrosiers M., Brambati S., Doyon J., Sarica A., Vasta R., Cerasa A., Quattrone A., Yeatman J., Khan A.R., Hodges W., Alexander S., Romascano D., Barakovic M., Auria A., Esteban O., Lemkaddem A., Thiran J.P., Cetingul H.E., Odry B.L., Mailhe B., Nadar M.S., Pizzagalli F., Prasad G., Villalon-Reina J.E., Galvis J., Thompson P.M., Requejo F.S., Laguna P.L., Lacerda L.M., Barrett R., Dell'Acqua F., Calani M., Petit L., Caruyer E., Daducci A., Dyrby T.B., Holland-Letz T., Hilgetag C.C., Stieltjes B., Descoteaux M.: The challenge of mapping the human connectome based on diffusion tractography. Nat.Commun. 8 (1) 1349, 2017.

Maierthaler M., Benner A., Hoffmeister M., Surowy H., Jansen L., Knebel P., Chang-Claude J., Brenner H., Burwinkel B.: Plasma miR-122 and miR-200 family are prognostic markers in colorectal cancer. Int.J.Cancer 140 (1) 176-187, 2017.

Merz M., Jauch A., Hielscher T., Mai E.K., Seckinger A., Hose D., Bertsch U., Neben K., Raab M.S., Salwender H., Blau I.W., Lindemann H.W., Schmidt-Wolf I., Scheid C., Hänel M., Weisel K., Goldschmidt H., Hillengass J.: Longitudinal fluorescence in situ hybridization reveals cytogenetic evolution in myeloma relapsing after autologous transplantation. Haematologica 102 (8) 1432-1438, 2017.

Popovic Z.V., Embgenbroich M., Chessa F., Nordström V., Bonrouhi M., Hielscher T., Gretz N., Wang S., Mathow D., Quast T., Kolanus W., Burgdorf S., Gröne H.J.: Hyperosmolarity impedes the cross-priming competence of dendritic cells in a TRIF-dependent manner. Sci.Rep. 7 (1) 311, 2017.

Radtke J.P., Wiesenfarth M., Kesch C., Freitag M.T., Alt C.D., Celik K., Distler F., Roth W., Wieczorek K., Stock C., Dünsing S., Röthke M.C., Teber D., Schlemmer H.P., Hohenfellner M., Bonekamp D., Hadaschik B.A.: Combined clinical parameters and multiparametric magnetic resonance imaging for advanced risk modeling of prostate cancer-patient-tailored risk stratification can reduce unnecessary biopsies. Europ.Urol. S0302-2838 (17) 30267-30271, 2017.

Radujkovic A., Kordelas L., Krzykalla J., Beelen D.W., Benner A., Lehners N., Schmidt K., Dreger P., Luft T.: Pretransplant vitamin D deficiency Is associated with higher relapse rates in patients allografted for myeloid malignancies. J.Clin.Oncol. 35 (27) 3143-3152, 2017.

Ramin M., Holland-Letz T., Schwab A., Schenkel J.: Age-related yields of mouse sperm and oocytes. J.Anim.Res.Nutrit. 2 (22) 1-6, 2017.

Sahm F., Toprak U.H., Hübschmann D., Kleinheinz K., Buchhalter I., Sill M., Stichel D., Schick M., Bewerunge-Hudler M., Schrimpf D., Zadeh G., Aldape K., Herold-Mende C., Beck K., Staszweski O., Prinz M., Harosch C.B., Eils R., Sturm D., Jones D.T.W., Pfister S.M., Paulus W., Ram Z., Schlesner M., Grossman R., von Deimling A.: Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature. Acta Neuropathol. 134 (1) 155-158, 2017.

Sahm F., Schrimpf D., Stichel D., Jones D.T.W., Hielscher T., Schefzyk S., Okonechnikov K., Kölsche C., Reuss D., Capper D., Sturm D., Wirsching H.G., Berghoff A.S., Baumgarten P., Kratz A., Huang K., Wefers A., Hovestadt V., Sill M., Ellis H., Kurian K., Okuducu A., Jungk C., Drueschler K., Schick M., Bewerunge-Hudler M., Mawrin C., Seiz-Rosenhagen M., Ketter R., Simon M., Westphal M., Lamszus K., Becker A., Koch A., Schittenhelm J., Rushing E., Collins V.P., Brehmer S., Chavez L., Platten M., Hänggi D., Unterberg A., Paulus W., Wick W., Pfister S., Mittelbronn M., Preusser M., Herold-Mende C., Weller M., Deimling A.v.: DNA methylation-based classification and grading system for meningioma: A multi-centre, retrospective analysis. Lancet Oncol. 18 (5) 682-694, 2017.

Schlenk R.F., Müller-Tidow C., Benner A., Kieser M.: Relapsed/refractory acute myeloid leukemia: any progress? Curr.Opin.Oncol. 29 (6) 467-473, 2017.

Schlenk R.F., Stegelmann F., Reiter A., Jost E., Gattermann N., Hebart H., Waller C., Hochhaus A., Platzbecker U., Schaffhausen P., Blau I.W., Verbeek W., Heidel F.H., Werner M., Kreipe H., Teleanu V., Benner A., Döhner H., Grießhammer M., Döhner K.: Pomalidomide in myeloproliferative neoplasm-associated myelofibrosis. Leukem. 31 (4) 889-895, 2017.

Schönsteiner S.S., Bauder-Mißbach H., Benner A., Mack S., Hamel T., Orth M., Landwehrmeyer B., Süßmuth S.D., Geitner C., Mayer-Steinacker R., Riester A., Prokein A., Erhardt E., Kunecki J., Eisenschink A.M., Rawer R., Döhner H., Kirchner E., Schlenk R.F.: A randomized exploratory phase 2 study in patients with chemotherapy-related peripheral neuropathy evaluating whole-body vibration training as adjunct to an integrated program including massage, passive mobilization and physical exercises. Exp.Hematol.Oncol. 6 (5) 1-11, 2017.

Schröder L., Boscolo-Rizzo P., Dal Cin E., Romeo S., Baboci L., Dyckhoff G., Hess J., Lucena-Porcel C., Byl A., Becker N., Alemany L., Castellsague X., Quer M., Leon X., Wiesenfarth M., Pawlita M., Holzinger D.: Human papillomavirus as prognostic marker with rising prevalence in neck squamous cell carcinoma of unknown primary: A retrospective multicentre study. Eur.J.Cancer 74 (73) 81, 2017.

Selt F., Hohloch J., Hielscher T., Sahm F., Capper D., Korshunov A., Usta D., Brabetz S., Ridinger J., Ecker J., Öhme I., Gronych J., Marquardt V., Pauck D., Bächli H., Stiles C., von Deimling A., Remke M., Schuhmann M., Pfister S., Brummer T., Jones D., Witt O., Milde T.: Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing. Oncotarget 8 (7) 11460-11479, 2017.

Shumilov A., Tsai M.H., Schlosser Y.T., Kratz A.S., Bernhardt K., Fink S., Mizani T., Lin X., Jauch A., Mautner J., Kopp-Schneider A., Feederle R., Hoffmann I., Delecluse H.J.: Epstein-Barr virus particles induce centrosome amplification and chromosomal instability. Nat.Commun. 8 14257, 2017.

Thole T.M., Lodrini M., Fabian J., Wünschel J., Pfeil S., Hielscher T., Kopp-Schneider A., Heinike U., Fulda S., Witt O., Eggert A., Fischer M., Deubzer H.E.: Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival. Cell Death Dis. 8 (3) e2635, 2017.

Tichy D., Pickl J.M.A., Benner A., Sültmann H.: Experimental design and data analysis of Ago-RIP-Seq experiments for the identification of microRNA targets. Brief.Bioinformat. (epub) , 2017.

Tsai M.H., Lin X., Shumilov A., Bernhardt K., Feederle R., Poirey R., Kopp-Schneider A., Pereira B., Almeida R., Delecluse H.J.: The biological properties of different Epstein-Barr virus strains explain their association with various types of cancers. Oncotarget 8 (6) 10238-10254, 2017.

Ugurel S., Loquai C., Terheyden P., Schadendorf D., Richtig E., Utikal J., Gutzmer R., Rass K., Sunderkötter C., Stein A., Fluck M., Kaatz M., Trefzer U., Kähler K., Stadler R., Berking C., Höller C., Kerschke L., Edler L., Kopp-Schneider A., Becker J.C.: Chemosensitivity-directed therapy compared to dacarbazine in chemo-naive advanced metastatic melanoma: a multicenter randomized phase-3 DeCOG trial. Oncotarget 8 (76029) 76043, 2017.

Vinsensia M., Choyke P.L., Hadaschik B., Holland-Letz T., Moltz J., Kopka K., Rauscher I., Mier W., Schwaiger M., Haberkorn U., Maurer T., Kratochwil C., Eiber M., Giesel F.: 68Ga-PSMA PET/CT and volumetric morphology of PET-positive lymph nodes stratified by tumor differentiation of prostate cancer. J.Nucl.Med. 58 (12) 1949-1955, 2017.

Wagener N., Edelmann D., Benner A., Zigeuner R., Borgmann H., Wolff I., Krabbe L.M., Musquera M., Dell'Oglio P., Capitanio U., Klatte T., Cindolo L., May M., Brookman-May S.D.: Outcome of papillary versus clear cell renal cell carcinoma varies significantly in non-metastatic disease. PLoS_ONE 12 (9) e0184173, 2017.

Wattad M., Weber D., Döhner K., Krauter J., Gaidzik V.I., Paschka P., Heuser M., Thol F., Kindler T., Lübbert M., Salih H.R., Kündgen A., Horst H.A., Brossart P., Götze K., Nachbaur D., Köhne C.H., Ringhoffer M., Wulf G., Held G., Salwender H., Benner A., Ganser A., Döhner H., Schlenk R.F.: Impact of salvage regimens on response and overall survival in acute myeloid leukemia with induction failure. Leukem. 31 (6) 1306-1313, 2017.

Wolf M.B., Edler C., Tichy D., Röthke M.C., Schlemmer H.P., Herfarth K., Bonekamp D.: Diffusion-weighted MRI treatment monitoring of primary hypofractionated proton and carbon ion prostate cancer irradiation using raster scan technique. J.Magnet.Resonan.Imag. 46 (3) 850-860, 2017.

Zeisbrich M., Becker N., Benner A., Radujkovic A., Schmitt K., Beimler J., Ho A.D., Zeier M., Dreger P., Luft T.: Transplant-associated thrombotic microangiopathy is an endothelial complication associated with refractoriness of acute GvHD. Bone Marrow Transplant. 52 (10) 1399-1405, 2017.

Zhan T., Hahn F., Hielscher T., Bilge A., Grüger J., Weers J., Betge J., Gaiser T., Kahler G., Ebert M.P., Belle S.: Multiple behavioral factors are associated with occurrence of large, flat colorectal polyps. Int.J.Colorect.Disease 32 (4) 575-582, 2017.

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