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Prof. Dr. Moritz Gerstung

Journal Article Panten, J. (First author)DKFZ* ; Del Prete, S. (First author)DKFZ* ; Cleland, J. (First author)DKFZ* ; Saunders, L. M.DKFZ* ; van Riet, J.DKFZ* ; Schneider, A.DKFZ* ; Ginno, P.DKFZ* ; Schneider, N.DKFZ* ; Koch, M.-L.DKFZ* ; Chen, X. ; Gerstung, M.DKFZ* ; Stegle, O.DKFZ* ; Arnold, A. P. ; Turner, J. M. A. ; Heard, E. ; Odom, D. (Last author)DKFZ*
Four Core Genotypes mice harbour a 3.2MB X-Y translocation that perturbs Tlr7 dosage.
Nature Communications 15(1), 8814 (2024) [10.1038/s41467-024-52640-8]2024 DBCoverage Files Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Herms, A. ; Fernandez-Antoran, D. ; Alcolea, M. P. ; Kalogeropoulou, A. ; Banerjee, U. ; Piedrafita, G. ; Abby, E. ; Valverde-Lopez, J. A. ; Ferreira, I. S. ; Caseda, I. ; Bejar, M. T. ; Dentro, S. C.DKFZ* ; Vidal-Notari, S. ; Ong, S. H. ; Colom, B. ; Murai, K. ; King, C. ; Mahbubani, K. ; Saeb-Parsy, K. ; Lowe, A. R. ; Gerstung, M.DKFZ* ; Jones, P. H.
Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium.
Nature genetics 56(10), 2158-2173 (2024) [10.1038/s41588-024-01875-8]2024 BibTeX | EndNote: XML, Text | RIS

Journal Article Jung, A. W. ; Holm, P. C. ; Gaurav, K. ; Hjaltelin, J. X. ; Placido, D. ; Mortensen, L. H. ; Birney, E. ; Brunak, S. R. ; Gerstung, M. (Last author)DKFZ*
Multi-cancer risk stratification based on national health data: a retrospective modelling and validation study.
The lancet / Digital health 6(6), e396 - e406 (2024) [10.1016/S2589-7500(24)00062-1]2024 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article De Zuani, M. ; Xue, H. ; Park, J. S. ; Dentro, S. C.DKFZ* ; Seferbekova, Z. ; Tessier, J. ; Curras-Alonso, S. ; Hadjipanayis, A. ; Athanasiadis, E. I. ; Gerstung, M.DKFZ* ; Bayraktar, O. ; Cvejic, A.
Single-cell and spatial transcriptomics analysis of non-small cell lung cancer.
Nature Communications 15(1), 4388 (2024) [10.1038/s41467-024-48700-8]2024 DBCoverage Files BibTeX | EndNote: XML, Text | RIS

Journal Article Jin, D. (First author)DKFZ* ; Liang, S. ; Shmatko, A.DKFZ* ; Arnold, A. ; Horst, D.DKFZ* ; Grünewald, T.DKFZ* ; Gerstung, M.DKFZ* ; Bai, X.
Teacher-student collaborated multiple instance learning for pan-cancer PDL1 expression prediction from histopathology slides.
Nature Communications 15(1), 3063 (2024) [10.1038/s41467-024-46764-0]2024 DBCoverage Files BibTeX | EndNote: XML, Text | RIS

Journal Article Marconato, L. (First author)DKFZ* ; Palla, G. ; Yamauchi, K. A. ; Virshup, I. ; Heidari, E.DKFZ* ; Treis, T.DKFZ* ; Vierdag, W.-M. ; Toth, M. ; Stockhaus, S. ; Shrestha, R. B. ; Rombaut, B. ; Pollaris, L. ; Lehner, L. ; Vöhringer, H. ; Kats, I.DKFZ* ; Saeys, Y. ; Saka, S. K. ; Huber, W. ; Gerstung, M.DKFZ* ; Moore, J. ; Theis, F. J. ; Stegle, O. (Last author)DKFZ*
SpatialData: an open and universal data framework for spatial omics.
Nature methods nn, nn (2024) [10.1038/s41592-024-02212-x]2024 BibTeX | EndNote: XML, Text | RIS

Journal Article Abby, E. ; Dentro, S.DKFZ* ; Hall, M. W. J. ; Fowler, J. C. ; Ong, S. H. ; Sood, R. ; Herms, A. ; Piedrafita, G. ; Abnizova, I. ; Siebel, C. W. ; Gerstung, M.DKFZ* ; Hall, B. A. ; Jones, P. H.
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth
Nature genetics 55(2), 232-245 (2023) [10.1038/s41588-022-01280-z]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Light, N. ; Layeghifard, M. ; Attery, A. ; Subasri, V. ; Zatzman, M. ; Anderson, N. D. ; Hatkar, R. ; Blay, S. ; Chen, D. ; Novokmet, A. ; Fuligni, F. ; Tran, J. ; de Borja, R. ; Agarwal, H. ; Waldman, L. ; Abegglen, L. M. ; Albertson, D. ; Finlay, J. L. ; Hansford, J. R. ; Behjati, S. ; Villani, A. ; Gerstung, M.DKFZ* ; Alexandrov, L. B. ; Somers, G. R. ; Schiffman, J. D. ; Rotter, V. ; Malkin, D. ; Shlien, A.
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis.
Nature Communications 14(1), 77 (2023) [10.1038/s41467-022-35727-y]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Seferbekova, Z. (First author)DKFZ* ; Lomakin, A. (First author)DKFZ* ; Yates, L. R. ; Gerstung, M. (Last author)DKFZ*
Spatial biology of cancer evolution.
Nature reviews / Genetics 24(5), 295-313 (2023) [10.1038/s41576-022-00553-x]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article (Erratum/Correction) Gu, M. ; Kovilakam, S. C. ; Dunn, W. G. ; Marando, L. ; Barcena, C. ; Mohorianu, I. ; Smith, A. ; Kar, S. P. ; Fabre, M. A. ; Gerstung, M.DKFZ* ; Cargo, C. A. ; Malcovati, L. ; Quiros, P. M. ; Vassiliou, G. S.
Author Correction: Multiparameter prediction of myeloid neoplasia risk.
Nature genetics 55(10), 1777 (2023) [10.1038/s41588-023-01532-6]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Gu, M. ; Kovilakam, S. C. ; Dunn, W. G. ; Marando, L. ; Barcena, C. ; Mohorianu, I. ; Smith, A. ; Kar, S. P. ; Fabre, M. A. ; Gerstung, M.DKFZ* ; Cargo, C. A. ; Malcovati, L. ; Quiros, P. M. ; Vassiliou, G. S.
Multiparameter prediction of myeloid neoplasia risk.
Nature genetics 55(9), 1523-1530 (2023) [10.1038/s41588-023-01472-1]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article de Almeida, J. G. ; Gudgin, E. ; Besser, M. ; Dunn, W. G. ; Cooper, J. ; Haferlach, T. ; Vassiliou, G. S. ; Gerstung, M. (Last author)DKFZ*
Computational analysis of peripheral blood smears detects disease-associated cytomorphologies.
Nature Communications 14(1), 4378 (2023) [10.1038/s41467-023-39676-y]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Jung, A. W. ; Gerstung, M. (Last author)DKFZ*
Bayesian Cox regression for large-scale inference with applications to electronic health records
The annals of applied statistics 17(2), 1064 - 1085 (2023) [10.1214/22-AOAS1658]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article (Erratum/Correction) Rubanova, Y. ; Shi, R. ; Harrigan, C. F. ; et al
Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
Nature Communications 13(1), 7567 (2022) [10.1038/s41467-022-32336-7]2022 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Lomakin, A. (First author)DKFZ* ; Svedlund, J. ; Strell, C. ; Gataric, M. ; Shmatko, A.DKFZ* ; Rukhovich, G.DKFZ* ; Park, J. S.DKFZ* ; Ju, Y. S. ; Dentro, S.DKFZ* ; Kleshchevnikov, V. ; Vaskivskyi, V. ; Li, T. ; Bayraktar, O. A. ; Pinder, S. ; Richardson, A. L. ; Santagata, S. ; Campbell, P. J. ; Russnes, H. ; Gerstung, M.DKFZ* ; Nilsson, M. ; Yates, L. R.
Spatial genomics maps the structure, nature and evolution of cancer clones.
Nature <London> 611(7936), 594 - 602 (2022) [10.1038/s41586-022-05425-2]2022 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Shmatko, A. (First author)DKFZ* ; Ghaffari Laleh, N. ; Gerstung, M.DKFZ* ; Kather, J. N.
Artificial intelligence in histopathology: enhancing cancer research and clinical oncology.
Nature cancer 3(9), 1026 - 1038 (2022) [10.1038/s43018-022-00436-4]2022 BibTeX | EndNote: XML, Text | RIS

Preprint de Almeida, J. G. ; Gudgin, E. ; Besser, M. ; Dunn, W. G. ; Cooper, J. ; Haferlach, T. ; Vassiliou, G. S. ; Gerstung, M. (Last author)DKFZ*
Computational analysis of peripheral blood smears detects disease-associated cytomorphologies
[10.1101/2022.04.19.22273757] BibTeX | EndNote: XML, Text | RIS

Preprint Abbott, S. ; Sherratt, K. ; Gerstung, M.DKFZ* ; Funk, S.
Estimation of the test to test distribution as a proxy for generation interval distribution for the Omicron variant in England
[10.1101/2022.01.08.22268920] BibTeX | EndNote: XML, Text | RIS

Preprint Murai, K. ; Dentro, S.Extern* ; Ong, S. H. ; Sood, R. ; Fernandez-Antoran, D. ; Herms, A. ; Kostiou, V. ; Hall, B. A. ; Gerstung, M.Extern* ; Jones, P. H.
p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition
[10.1101/2022.02.03.478951] BibTeX | EndNote: XML, Text | RIS

Journal Article Demeulemeester, J. ; Dentro, S.Extern* ; Gerstung, M.Extern* ; Van Loo, P.
Biallelic mutations in cancer genomes reveal local mutational determinants.
Nature genetics 54(2), 128 - 133 (2022) [10.1038/s41588-021-01005-8]2022 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article (Erratum/Correction) Vöhringer, H. S. ; Sanderson, T. ; Sinnott, M. ; et al
Publisher Correction: Genomic reconstruction of the SARS CoV-2 epidemic in England
Nature <London> 606(7915), E18 - E18 (2022) [10.1038/s41586-022-04887-8]2022 BibTeX | EndNote: XML, Text | RIS

Journal Article Fabre, M. A. ; de Almeida, J. G. ; Fiorillo, E. ; Mitchell, E. ; Damaskou, A. ; Rak, J. ; Orrù, V. ; Marongiu, M. ; Chapman, M. S. ; Vijayabaskar, M. S. ; Baxter, J. ; Hardy, C. ; Abascal, F. ; Williams, N. ; Nangalia, J. ; Martincorena, I. ; Campbell, P. J. ; McKinney, E. F. ; Cucca, F. ; Gerstung, M.DKFZ* ; Vassiliou, G. S.
The longitudinal dynamics and natural history of clonal haematopoiesis.
Nature <London> 606(7913), 335-342 (2022) [10.1038/s41586-022-04785-z]2022 BibTeX | EndNote: XML, Text | RIS

Journal Article Cagan, A. ; Baez-Ortega, A. ; Brzozowska, N. ; Abascal, F. ; Coorens, T. H. H. ; Sanders, M. A. ; Lawson, A. R. J. ; Harvey, L. M. R. ; Bhosle, S. ; Jones, D. ; Alcantara, R. E. ; Butler, T. M. ; Hooks, Y. ; Roberts, K. ; Anderson, E. ; Lunn, S. ; Flach, E. ; Spiro, S. ; Januszczak, I. ; Wrigglesworth, E. ; Jenkins, H. ; Dallas, T. ; Masters, N. ; Perkins, M. W. ; Deaville, R. ; Druce, M.DKFZ* ; Bogeska, R.DKFZ* ; Milsom, M.DKFZ* ; Neumann, B. ; Gorman, F. ; Constantino-Casas, F. ; Peachey, L. ; Bochynska, D. ; Smith, E. S. J. ; Gerstung, M.Extern* ; Campbell, P. J. ; Murchison, E. P. ; Stratton, M. R. ; Martincorena, I.
Somatic mutation rates scale with lifespan across mammals.
Nature <London> 604(7906), 517 - 524 (2022) [10.1038/s41586-022-04618-z]2022 BibTeX | EndNote: XML, Text | RIS

Journal Article Kleshchevnikov, V. ; Shmatko, A.Extern* ; Dann, E. ; Aivazidis, A. ; King, H. W. ; Li, T. ; Elmentaite, R. ; Lomakin, A.Extern* ; Kedlian, V. ; Gayoso, A. ; Jain, M. S. ; Park, J. S. ; Ramona, L. ; Tuck, E. ; Arutyunyan, A. ; Vento-Tormo, R. ; Gerstung, M.Extern* ; James, L. ; Stegle, O.DKFZ* ; Bayraktar, O. A.
Cell2location maps fine-grained cell types in spatial transcriptomics
Nature biotechnology 40(5), 661-671 (2022) [10.1038/s41587-021-01139-4]2022 BibTeX | EndNote: XML, Text | RIS

Preprint Fabre, M. A. ; Almeida, J. G. d. ; Fiorillo, E. ; Mitchell, E. ; Damaskou, A. ; Rak, J. ; Orrù, V. ; Marongiu, M. ; Vijayabaskar, M. ; Baxter, J. ; Hardy, C. ; Abascal, F. ; Chapman, M. S. ; Williams, N. ; Nangalia, J. ; Martincorena, I. ; Campbell, P. J. ; McKinney, E. F. ; Cucca, F. ; Gerstung, M.Extern* ; Vassiliou., G. S.
The longitudinal dynamics and natural history of clonal haematopoiesis
[10.1038/s41586-022-04785-z] BibTeX | EndNote: XML, Text | RIS

Journal Article Dentro, S.Extern* ; Leshchiner, I. ; Haase, K. ; et al
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
Cell 184(8), 2239 - 2254.e39 (2021) [10.1016/j.cell.2021.03.009]2021 BibTeX | EndNote: XML, Text | RIS

Preprint Sanders, M. A. ; Vöhringer, H. ; Forster, V. J. ; Moore, L. ; Campbell, B. B. ; Hooks, Y. ; Edwards, M. ; Bianchi, V. ; Coorens, T. H. H. ; Butler, T. M. ; Lee-Six, H. ; Robinson, P. S. ; Flensburg, C. ; Bilardi, R. A. ; Majewski, I. J. ; Reschke, A. ; Cairney, E. ; Crooks, B. ; Lindhorst, S. ; Stearns, D. ; Tomboc, P. ; McDermott, U. ; Stratton, M. R. ; Shlien, A. ; Gerstung, M.Extern* ; Tabori, U. ; Campbell, P. J.
Life without mismatch repair
[10.1101/2021.04.14.437578] BibTeX | EndNote: XML, Text | RIS

Preprint Gataric, M. ; Park, J. S. ; Li, T. ; Vaskivskyi, V. ; Svedlund, J. ; Strell, C. ; Roberts, K. ; Nilsson, M. ; Yates, L. R. ; Bayraktar, O. ; Gerstung, M. (Last author)DKFZ*
PoSTcode: Probabilistic image-based spatial transcriptomics decoder
[10.1101/2021.10.12.464086] BibTeX | EndNote: XML, Text | RIS

Preprint Abby, E. ; Dentro, S.Extern* ; Hall, M. W. J. ; Fowler, J. C. ; Ong, S. H. ; Sood, R. ; Siebel, C. W. ; Gerstung, M.Extern* ; Hall, B. A. ; Jones, P. H.
Notch1 mutation drives clonal expansion in normal esophageal epithelium but impairs tumor growth
[10.1101/2021.06.18.448956] BibTeX | EndNote: XML, Text | RIS

Preprint Lomakin, A.Extern* ; Svedlund, J. ; Strell, C. ; Gataric, M. ; Shmatko, A. ; Park, J. S. ; Ju, Y. S. ; Dentro, S.Extern* ; Kleshchevnikov, V. ; Vaskivskyi, V. ; Li, T. ; Bayraktar, O. A. ; Moore, L. ; Pinder, S. ; Richardson, A. L. ; Campbell, P. J. ; Gerstung, M.Extern* ; Nilsson, M. ; Yates, L. R.
Spatial genomics maps the structure, character and evolution of cancer clones
[10.1101/2021.04.16.439912] BibTeX | EndNote: XML, Text | RIS

Journal Article Abascal, F. ; Harvey, L. M. R. ; Mitchell, E. ; Lawson, A. R. J. ; Lensing, S. V. ; Ellis, P. ; Russell, A. J. C. ; Alcantara, R. E. ; Baez-Ortega, A. ; Wang, Y. ; Kwa, E. J. ; Lee-Six, H. ; Cagan, A. ; Coorens, T. H. H. ; Chapman, M. S. ; Olafsson, S. ; Leonard, S. ; Jones, D. ; Machado, H. E. ; Davies, M. ; Øbro, N. F. ; Mahubani, K. T. ; Allinson, K. ; Gerstung, M.Extern* ; Saeb-Parsy, K. ; Kent, D. G. ; Laurenti, E. ; Stratton, M. R. ; Rahbari, R. ; Campbell, P. J. ; Osborne, R. J. ; Martincorena, I.
Somatic mutation landscapes at single-molecule resolution.
Nature <London> 593(7859), 405 - 410 (2021) [10.1038/s41586-021-03477-4]2021 BibTeX | EndNote: XML, Text | RIS

Journal Article Meier, B. ; Volkova, N. V. ; Hong, Y. ; Bertolini, S. ; González-Huici, V. ; Petrova, T. ; Boulton, S. ; Campbell, P. J. ; Gerstung, M.Extern* ; Gartner, A.
Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation.
PLOS ONE 16(4), e0250291 - (2021) [10.1371/journal.pone.0250291]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Tonkin-Hill, G. ; Martincorena, I. ; Amato, R. ; Lawson, A. R. J. ; Gerstung, M.Extern* ; Johnston, I. ; Jackson, D. K. ; Park, N. ; Lensing, S. V. ; Quail, M. A. ; Gonçalves, S. ; Ariani, C. ; Spencer Chapman, M. ; Hamilton, W. L. ; Meredith, L. W. ; Hall, G. ; Jahun, A. S. ; Chaudhry, Y. ; Hosmillo, M. ; Pinckert, M. L. ; Georgana, I. ; Yakovleva, A. ; Caller, L. G. ; Caddy, S. L. ; Feltwell, T. ; Khokhar, F. A. ; Houldcroft, C. J. ; Curran, M. D. ; Parmar, S. ; UK, C. G. (Collaboration Author) ; Alderton, A. ; Nelson, R. ; Harrison, E. M. ; Sillitoe, J. ; Bentley, S. D. ; Barrett, J. C. ; Torok, M. E. ; Goodfellow, I. G. ; Langford, C. ; Kwiatkowski, D. ; Team, W. S. I. C. S. (Collaboration Author)
Patterns of within-host genetic diversity in SARS-CoV-2.
eLife 10, e66857 (2021) [10.7554/eLife.66857]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Colom, B. ; Herms, A. ; Hall, M. W. J. ; Dentro, S.Extern* ; King, C. ; Sood, R. K. ; Alcolea, M. P. ; Piedrafita, G. ; Fernandez-Antoran, D. ; Ong, S. H. ; Fowler, J. C. ; Mahbubani, K. T. ; Saeb-Parsy, K. ; Gerstung, M.Extern* ; Hall, B. A. ; Jones, P. H.
Mutant clones in normal epithelium outcompete and eliminate emerging tumours.
Nature <London> 598(7881), 510 - 514 (2021) [10.1038/s41586-021-03965-7]2021 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Meier, B. ; Volkova, N. V. ; Wang, B. ; González-Huici, V. ; Bertolini, S. ; Campbell, P. J. ; Gerstung, M.Extern* ; Gartner, A.
C. elegans genome-wide analysis reveals DNA repair pathways that act cooperatively to preserve genome integrity upon ionizing radiation.
PLOS ONE 16(10), e0258269 - (2021) [10.1371/journal.pone.0258269]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Vöhringer, H. ; Hoeck, A. V. ; Cuppen, E. ; Gerstung, M.Extern*
Learning mutational signatures and their multidimensional genomic properties with TensorSignatures
Nature Communications 12(1), 3628 (2021) [10.1038/s41467-021-23551-9]2021 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Anderson, N. D. ; Babichev, Y. ; Fuligni, F. ; Comitani, F. ; Layeghifard, M. ; Venier, R. E. ; Dentro, S.Extern* ; Maheshwari, A. ; Guram, S. ; Wunker, C. ; Thompson, J. D. ; Yuki, K. E. ; Hou, H. ; Zatzman, M. ; Light, N. ; Bernardini, M. Q. ; Wunder, J. S. ; Andrulis, I. L. ; Ferguson, P. ; Razak, A. R. A. ; Swallow, C. J. ; Dowling, J. J. ; Al-Awar, R. S. ; Marcellus, R. ; Rouzbahman, M. ; Gerstung, M.Extern* ; Durocher, D. ; Alexandrov, L. B. ; Dickson, B. C. ; Gladdy, R. A. ; Shlien, A.
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival.
Nature Communications 12(1), 4496 (2021) [10.1038/s41467-021-24677-6]2021 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Preprint Cagan, A. ; Baez-Ortega, A. ; Brzozowska, N. ; Abascal, F. ; Coorens, T. H. H. ; Sanders, M. A. ; Lawson, A. R. J. ; Harvey, L. M. R. ; Bhosle, S. G. ; Jones, D. ; Alcantara, R. E. ; Butler, T. M. ; Hooks, Y. ; Roberts, K. ; Anderson, E. ; Flach, E. ; Spiro, S. ; Januszczak, I. ; Wrigglesworth, E. ; Perkins, M. W. ; Deaville, R. ; Druce, M.DKFZ* ; Bogeska, R.DKFZ* ; Milsom, M. D.DKFZ* ; Neumann, B. ; Gorman, F. ; Constantino-Casas, F. ; Peachey, L. ; Bochynska, D. ; Smith, E. S. J. ; Gerstung, M.DKFZ* ; Campbell, P. J. ; Murchison, E. P. ; Stratton, M. R. ; Martincorena, I. (Corresponding author)
Somatic mutation rates scale with lifespan across mammals
bioRxiv beta (2021) [https://doi.org/10.1101/2021.08.19.456982]2021 Fulltext BibTeX | EndNote: XML, Text | RIS

Journal Article Vöhringer, H. S. ; Sanderson, T. ; Sinnott, M. ; De Maio, N. ; Nguyen, T. ; Goater, R. ; Schwach, F. ; Harrison, I. ; Hellewell, J. ; Ariani, C. V. ; Gonçalves, S. ; Jackson, D. K. ; Johnston, I. ; Jung, A. W. ; Saint, C. ; Sillitoe, J. ; Suciu, M. ; Goldman, N. ; Panovska-Griffiths, J. ; Team, W. S. I. C. S. (Collaboration Author) ; UK, C. G. (Collaboration Author) ; Birney, E. ; Volz, E. ; Funk, S. ; Kwiatkowski, D. ; Chand, M. ; Martincorena, I. ; Barrett, J. C. ; Gerstung, M. (Last author)DKFZ*
Genomic reconstruction of the SARS-CoV-2 epidemic in England.
Nature <London> 600(7889), 506-511 (2021) [10.1038/s41586-021-04069-y]2021 BibTeX | EndNote: XML, Text | RIS

Preprint Volkova, N. V. ; Meier, B. ; González-Huici, V. ; Bertolini, S. ; Gonzalez, S. ; Voeringer, H. ; Abascal, F. ; Martincorena, I. ; Campbell, P. J. ; Gartner, A. ; Gerstung, M.Extern*
Mutational signatures are jointly shaped by DNA damage and repair
[10.1101/686295] BibTeX | EndNote: XML, Text | RIS

Preprint Fu, Y. ; Jung, A. W. ; Torne, R. V. ; Gonzalez, S. ; Vöhringer, H. ; Shmatko, A. ; Yates, L. ; Jimenez-Linan, M. ; Moore, L. ; Gerstung, M.Extern*
Pan-cancer computational histopathology reveals mutations, tumor composition and prognosis
[10.1101/813543] BibTeX | EndNote: XML, Text | RIS

Preprint Killcoyne, S. ; Gregson, E. ; Wedge, D. C. ; Woodcock, D. J. ; Eldridge, M. ; de la Rue, R. ; Miremadi, A. ; Abbas, S. ; Blasko, A. ; Januszewicz, W. ; Varanou Jenkins, A. ; Gerstung, M.Extern* ; Fitzgerald, R. C.
Genomic copy number predicts oesophageal cancer years before transformation
[10.1101/2020.02.27.967612] BibTeX | EndNote: XML, Text | RIS

Preprint Tonkin-Hill, G. ; Martincorena, I. ; Amato, R. ; Lawson, A. R. J. ; Gerstung, M.Extern* ; Johnston, I. ; Jackson, D. K. ; Park, N. R. ; Lensing, S. V. ; Quail, M. A. ; Gonçalves, S. ; Ariani, C. ; Chapman, M. S. ; Hamilton, W. L. ; Meredith, L. W. ; Hall, G. ; Jahun, A. S. ; Chaudhry, Y. ; Hosmillo, M. ; Pinckert, M. L. ; Georgana, I. ; Yakovleva, A. ; Caller, L. G. ; Caddy, S. L. ; Feltwell, T. ; Khokhar, F. A. ; Houldcroft, C. J. ; Curran, M. D. ; Parmar, S. ; Alderton, A. ; Nelson, R. ; Harrison, E. ; Sillitoe, J. ; Bentley, S. D. ; Barrett, J. C. ; Torok, M. E. ; Goodfellow, I. G. ; Langford, C. ; Kwiatkowski, D.
Patterns of within-host genetic diversity in SARS-CoV-2
[10.1101/2020.12.23.424229] BibTeX | EndNote: XML, Text | RIS

Journal Article Li, C. H. ; Prokopec, S. D. ; Sun, R. X. ; et al
Sex differences in oncogenic mutational processes
Nature Communications 11(1), 4330 (2020) [10.1038/s41467-020-17359-2]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Preprint Meier, B. ; Volkova, N. ; Hong, Y. ; Bertolini, S. ; González-Huici, V. ; Petrova, T. ; Boulton, S. ; Campbell, P. ; Gerstung, M.Extern* ; Gartner, A.
Systematic analysis of mutational spectra associated with DNA repair deficiency in C. elegans
[10.1101/2020.06.04.133306] BibTeX | EndNote: XML, Text | RIS

Preprint Kleshchevnikov, V. ; Shmatko, A.Extern* ; Dann, E. ; Aivazidis, A. ; King, H. W. ; Li, T. ; Lomakin, A.Extern* ; Kedlian, V. ; Jain, M. S. ; Park, J. S. ; Ramona, L. ; Tuck, E. ; Arutyunyan, A. ; Vento-Tormo, R. ; Gerstung, M.Extern* ; James, L. ; Stegle, O.DKFZ* ; Bayraktar, O. A.
Comprehensive mapping of tissue cell architecture via integrated single cell and spatial transcriptomics
bioRxiv (2020) [10.1101/2020.11.15.378125]2020 BibTeX | EndNote: XML, Text | RIS

Journal Article Volkova, N. V. ; Meier, B. ; González-Huici, V. ; Bertolini, S. ; Gonzalez, S. ; Vöhringer, H. ; Abascal, F. ; Martincorena, I. ; Campbell, P. J. ; Gartner, A. ; Gerstung, M.Extern*
Mutational signatures are jointly shaped by DNA damage and repair
Nature Communications 11(1), 2169 (2020) [10.1038/s41467-020-15912-7]2020 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Volkova, N. V. ; Meier, B. ; González-Huici, V. ; Bertolini, S. ; Gonzalez, S. ; Vöhringer, H. ; Abascal, F. ; Martincorena, I. ; Campbell, P. J. ; Gartner, A. ; Gerstung, M.Extern*
Mutational signatures are jointly shaped by DNA damage and repair.
Nature Communications 11(1), 2169 (2020) [10.1038/s41467-020-15912-7]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Fu, Y. ; Jung, A. W. ; Torne, R. V. ; Gonzalez, S. ; Vöhringer, H. ; Shmatko, A.Extern* ; Yates, L. R. ; Jimenez-Linan, M. ; Moore, L. ; Gerstung, M.Extern*
Pan-cancer computational histopathology reveals mutations, tumor composition and prognosis
Nature cancer 1(8), 800 - 810 (2020) [10.1038/s43018-020-0085-8]2020 BibTeX | EndNote: XML, Text | RIS

Journal Article Meier, B. ; Volkova, N. V. ; Gerstung, M.Extern* ; Gartner, A.
Analysis of mutational signatures in C. elegans: Implications for cancer genome analysis.
DNA repair 95, 102957 (2020) [10.1016/j.dnarep.2020.102957]2020 BibTeX | EndNote: XML, Text | RIS

Journal Article (Letter) Killcoyne, S. ; Gregson, E. ; Wedge, D. C. ; Woodcock, D. J. ; Eldridge, M. D. ; de la Rue, R. ; Miremadi, A. ; Abbas, S. ; Blasko, A. ; Kosmidou, C. ; Januszewicz, W. ; Jenkins, A. V. ; Gerstung, M.Extern* ; Fitzgerald, R. C.
Genomic copy number predicts esophageal cancer years before transformation.
Nature medicine 26(11), 1726 - 1732 (2020) [10.1038/s41591-020-1033-y]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Lawson, A. R. J. ; Abascal, F. ; Coorens, T. H. H. ; Hooks, Y. ; O'Neill, L. ; Latimer, C. ; Raine, K. ; Sanders, M. A. ; Warren, A. Y. ; Mahbubani, K. T. A. ; Bareham, B. ; Butler, T. M. ; Harvey, L. M. R. ; Cagan, A. ; Menzies, A. ; Moore, L. ; Colquhoun, A. J. ; Turner, W. ; Thomas, B. ; Gnanapragasam, V. ; Williams, N. ; Rassl, D. M. ; Vöhringer, H. ; Zumalave, S. ; Nangalia, J. ; Tubío, J. M. C. ; Gerstung, M.Extern* ; Saeb-Parsy, K. ; Stratton, M. R. ; Campbell, P. J. ; Mitchell, T. J. ; Martincorena, I.
Extensive heterogeneity in somatic mutation and selection in the human bladder.
Science / Science now 370(6512), 75 - 82 (2020) [10.1126/science.aba8347]2020 BibTeX | EndNote: XML, Text | RIS

Journal Article Colom, B. ; Alcolea, M. P. ; Piedrafita, G. ; Hall, M. W. J. ; Wabik, A. ; Dentro, S.Extern* ; Fowler, J. C. ; Herms, A. ; King, C. ; Ong, S. H. ; Sood, R. K. ; Gerstung, M.Extern* ; Martincorena, I. ; Hall, B. A. ; Jones, P. H.
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.
Nature genetics 52(6), 604 - 614 (2020) [10.1038/s41588-020-0624-3]2020 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Bailey, M. H. ; Meyerson, W. U. ; Dursi, L. J. ; et al
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Nature Communications 11(1), 4748 (2020) [10.1038/s41467-020-18151-y]2020 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Preprint Vöhringer, H. ; van Hoeck, A. ; Cuppen, E. ; Gerstung, M.Extern*
Learning mutational signatures and their multidimensional genomic properties with TensorSignatures
[10.1101/850453] BibTeX | EndNote: XML, Text | RIS

Journal Article Maura, F. ; Bolli, N. ; Angelopoulos, N. ; Dawson, K. J. ; Leongamornlert, D. ; Martincorena, I. ; Mitchell, T. J. ; Fullam, A. ; Gonzalez, S. ; Szalat, R. ; Abascal, F. ; Rodriguez-Martin, B. ; Samur, M. K. ; Glodzik, D. ; Roncador, M. ; Fulciniti, M. ; Tai, Y. T. ; Minvielle, S. ; Magrangeas, F. ; Moreau, P. ; Corradini, P. ; Anderson, K. C. ; Tubio, J. M. C. ; Wedge, D. C. ; Gerstung, M.Extern* ; Avet-Loiseau, H. ; Munshi, N. ; Campbell, P. J.
Genomic landscape and chronological reconstruction of driver events in multiple myeloma.
Nature Communications 10(1), 3835 (2019) [10.1038/s41467-019-11680-1]2019 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Sasca, D. ; Yun, H. ; Giotopoulos, G. ; Szybinski, J. ; Evan, T. ; Wilson, N. K. ; Gerstung, M.Extern* ; Gallipoli, P. ; Green, A. R. ; Hills, R. ; Russell, N. ; Osborne, C. S. ; Papaemmanuil, E. ; Göttgens, B. ; Campbell, P. ; Huntly, B. J. P.
Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies
Blood 134(24), 2195 - 2208 (2019) [10.1182/blood.2019001553]2019 BibTeX | EndNote: XML, Text | RIS

Preprint Dentro, S.Extern* ; Leshchiner, I. ; Haase, K. ; Tarabichi, M. ; Wintersinger, J. ; Deshwar, A. G. ; Yu, K. ; Rubanova, Y. ; Macintyre, G. ; Demeulemeester, J. ; Vázquez-García, I. ; Kleinheinz, K.DKFZ* ; Livitz, D. G. ; Malikic, S. ; Donmez, N. ; Sengupta, S. ; Anur, P. ; Jolly, C. ; Cmero, M. ; Rosebrock, D. ; Schumacher, S. ; Fan, Y. ; Fittall, M. ; Drews, R. M. ; Yao, X. ; Lee, J. ; Schlesner, M.DKFZ* ; Zhu, H. ; Adams, D. J. ; Getz, G. ; Boutros, P. C. ; Imielinski, M. ; Beroukhim, R. ; Sahinalp, S. C. ; Ji, Y. ; Peifer, M. ; Martincorena, I. ; Markowetz, F. ; Mustonen, V. ; Yuan, K. ; Gerstung, M.Extern* ; Spellman, P. T. ; Wang, W. ; Morris, Q. D. ; Wedge, D. C. ; Van Loo, P.
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
[10.1101/312041] BibTeX | EndNote: XML, Text | RIS

Preprint Maura, F. ; Bolli, N. ; Angelopoulos, N. ; Dawson, K. J. ; Leongamornlert, D. ; Martincorena, I. ; Mitchell, T. J. ; Fullam, A. ; Gonzalez, S. ; Szalat, R. ; Rodriguez-Martin, B. ; Samur, M. K. ; Glodzik, D. ; Roncador, M. ; Fulciniti, M. ; Tai, Y. T. ; Minvielle, S. ; Magrangeas, F. ; Moreau, P. ; Corradini, P. ; Anderson, K. C. ; Tubio, J. M. C. ; Wedge, D. C. ; Gerstung, M.Extern* ; Avet-Loiseau, H. ; Munshi, N. ; Campbell, P. J.
Genomic landscape and chronological reconstruction of driver events in multiple myeloma
[10.1101/388611] BibTeX | EndNote: XML, Text | RIS

Journal Article (Letter) Tarabichi, M. ; Martincorena, I. ; Gerstung, M.Extern* ; et al
Neutral tumor evolution?
Nature genetics 50(12), 1630 - 1633 (2018) [10.1038/s41588-018-0258-x]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Preprint Akdemir, K. C. ; Le, V. T. ; Killcoyne, S. ; King, D. A. ; Li, Y.-P. ; Tian, Y. ; Inoue, A. ; Amin, S. ; Robinson, F. S. ; Herrera, R. E. ; Lynn, E. J. ; Chan, K. ; Seth, S. ; Klimczak, L. J. ; Gerstung, M.Extern* ; Gordenin, D. A. ; O?Brien, J. ; Li, L. ; Verhaak, R. G. ; Campbell, P. ; Fitzgerald, R. ; Morrison, A. J. ; Dixon, J. R. ; Andrew Futreal, P.
Process-specific somatic mutation distributions vary with three-dimensional genome structure
[10.1101/426080] BibTeX | EndNote: XML, Text | RIS

Journal Article González, S. ; Volkova, N. ; Beer, P. ; Gerstung, M.Extern*
Immuno-oncology from the perspective of somatic evolution.
Seminars in cancer biology 52(Pt 2), 75 - 85 (2018) [10.1016/j.semcancer.2017.12.001]2018 BibTeX | EndNote: XML, Text | RIS

Journal Article Meier, B. ; Volkova, N. V. ; Hong, Y. ; Schofield, P. ; Campbell, P. J. ; Gerstung, M.Extern* ; Gartner, A.
Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers.
Genome research 28(5), 666 - 675 (2018) [10.1101/gr.226845.117]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Bolli, N. ; Biancon, G. ; Moarii, M. ; Gimondi, S. ; Li, Y. ; de Philippis, C. ; Maura, F. ; Sathiaseelan, V. ; Tai, Y.-T. ; Mudie, L. ; O'Meara, S. ; Raine, K. ; Teague, J. W. ; Butler, A. P. ; Carniti, C. ; Gerstung, M.Extern* ; Bagratuni, T. ; Kastritis, E. ; Dimopoulos, M. ; Corradini, P. ; Anderson, K. C. ; Moreau, P. ; Minvielle, S. ; Campbell, P. J. ; Papaemmanuil, E. ; Avet-Loiseau, H. ; Munshi, N. C.
Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.
Leukemia 32(12), 2604 - 2616 (2018) [10.1038/s41375-018-0037-9]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article (Erratum/Correction) Martincorena, I. ; Raine, K. M. ; Gerstung, M.Extern* ; Dawson, K. J. ; Haase, K. ; Van Loo, P. ; Davies, H. ; Stratton, M. R. ; Campbell, P. J.
Universal Patterns of Selection in Cancer and Somatic Tissues.
Cell 173(7), 1823 - (2018) [10.1016/j.cell.2018.06.001]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Sawas, T. ; Killcoyne, S. ; Iyer, P. G. ; et al
Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts.
Gastroenterology 155(6), 1720 - 1728.e4 (2018) [10.1053/j.gastro.2018.08.036]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Grinfeld, J. ; Nangalia, J. ; Baxter, E. J. ; Wedge, D. C. ; Angelopoulos, N. ; Cantrill, R. ; Godfrey, A. L. ; Papaemmanuil, E. ; Gundem, G. ; MacLean, C. ; Cook, J. ; O'Neil, L. ; O'Meara, S. ; Teague, J. W. ; Butler, A. P. ; Massie, C. E. ; Williams, N. ; Nice, F. L. ; Andersen, C. L. ; Hasselbalch, H. C. ; Guglielmelli, P. ; McMullin, M. F. ; Vannucchi, A. M. ; Harrison, C. N. ; Gerstung, M.Extern* ; Green, A. R. ; Campbell, P. J.
Classification and Personalized Prognosis in Myeloproliferative Neoplasms.
The New England journal of medicine 379(15), 1416 - 1430 (2018) [10.1056/NEJMoa1716614]2018 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Abelson, S. ; Collord, G. ; Ng, S. W. K. ; et al
Prediction of acute myeloid leukaemia risk in healthy individuals.
Nature <London> 559(7714), 400 - 404 (2018) [10.1038/s41586-018-0317-6]2018 BibTeX | EndNote: XML, Text | RIS

Journal Article (Letter) Ju, Y. S. ; Martincorena, I. ; Gerstung, M.Extern* ; Petljak, M. ; Alexandrov, L. B. ; Rahbari, R. ; Wedge, D. C. ; Davies, H. R. ; Ramakrishna, M. ; Fullam, A. ; Martin, S. ; Alder, C. ; Patel, N. ; Gamble, S. ; O'Meara, S. ; Giri, D. D. ; Sauer, T. ; Pinder, S. E. ; Purdie, C. A. ; Borg, Å. ; Stunnenberg, H. ; van de Vijver, M. ; Tan, B. K. T. ; Caldas, C. ; Tutt, A. ; Ueno, N. T. ; van 't Veer, L. J. ; Martens, J. W. M. ; Sotiriou, C. ; Knappskog, S. ; Span, P. N. ; Lakhani, S. R. ; Eyfjörd, J. E. ; Børresen-Dale, A.-L. ; Richardson, A. ; Thompson, A. M. ; Viari, A. ; Hurles, M. E. ; Nik-Zainal, S. ; Campbell, P. J. ; Stratton, M. R.
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo.
Nature <London> 543(7647), 714 - 718 (2017) [10.1038/nature21703]2017 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Gerstung, M.Extern* ; Papaemmanuil, E. ; Martincorena, I. ; Bullinger, L. ; Gaidzik, V. I. ; Paschka, P. ; Heuser, M. ; Thol, F. ; Bolli, N. ; Ganly, P. ; Ganser, A. ; McDermott, U. ; Döhner, K. ; Schlenk, R. F. ; Döhner, H. ; Campbell, P. J.
Precision oncology for acute myeloid leukemia using a knowledge bank approach.
Nature genetics 49(3), 332 - 340 (2017) [10.1038/ng.3756]2017 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Yates, L. R. ; Knappskog, S. ; Wedge, D. ; Farmery, J. H. R. ; Gonzalez, S. ; Martincorena, I. ; Alexandrov, L. B. ; Van Loo, P. ; Haugland, H. K. ; Lilleng, P. K. ; Gundem, G. ; Gerstung, M.Extern* ; Pappaemmanuil, E. ; Gazinska, P. ; Bhosle, S. G. ; Jones, D. ; Raine, K. ; Mudie, L. ; Latimer, C. ; Sawyer, E. ; Desmedt, C. ; Sotiriou, C. ; Stratton, M. R. ; Sieuwerts, A. M. ; Lynch, A. G. ; Martens, J. W. ; Richardson, A. L. ; Tutt, A. ; Lønning, P. E. ; Campbell, P. J.
Genomic Evolution of Breast Cancer Metastasis and Relapse.
Cancer cell 32(2), 169 - 184.e7 (2017) [10.1016/j.ccell.2017.07.005]2017 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Salgado, R. ; Moore, H. ; Martens, J. W. M. ; Lively, T. ; Malik, S. ; McDermott, U. ; Michiels, S. ; Moscow, J. A. ; Tejpar, S. ; McKee, T. ; Lacombe, D. ; IBCD-Faculty (Collaboration Author) ; Becker, R. ; Beer, P. ; Bergh, J. ; Bogaerts, J. ; Dovedi, S. ; Fojo, A. T. ; Gerstung, M.Extern* ; Golfinopoulos, V. ; Hewitt, S. ; Hochhauser, D. ; Juhl, H. ; Kinders, R. ; Lillie, T. ; Herbert, K. L. ; Maheswaran, S. ; Mesri, M. ; Nagai, S. ; Norstedt, I. ; O'Connor, D. ; Oliver, K. ; Oyen, W. J. G. ; Pignatti, F. ; Polley, E. ; Rosenfeld, N. ; Schellens, J. ; Schilsky, R. ; Schneider, E. ; Senderowicz, A. ; Tenhunen, O. ; van Dongen, A. ; Vietz, C. ; Wilking, N.
Societal challenges of precision medicine: Bringing order to chaos.
European journal of cancer 84, 325 - 334 (2017) [10.1016/j.ejca.2017.07.028]2017 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Martincorena, I. ; Raine, K. M. ; Gerstung, M.Extern* ; Dawson, K. J. ; Haase, K. ; Van Loo, P. ; Davies, H. ; Stratton, M. R. ; Campbell, P. J.
Universal Patterns of Selection in Cancer and Somatic Tissues.
Cell 171(5), 1029 - 1041.e21 (2017) [10.1016/j.cell.2017.09.042]2017 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Preprint Hauri, S. ; Comoglio, F. ; Seimiya, M. ; Gerstung, M.Extern* ; Glatter, T. ; Hansen, K. ; Aebersold, R. ; Paro, R. ; Gstaiger, M. ; Beisel, C.
A High Density Map for Navigating the Human Polycomb Complexome
[10.1101/059964] BibTeX | EndNote: XML, Text | RIS

Preprint Gerstung, M.Extern* ; Papaemmanuil, E. ; Martincorena, I. ; Bullinger, L. ; Gaidzik, V. I. ; Paschka, P. ; Heuser, M. ; Thol, F. ; Bolli, N. ; Ganly, P. ; Ganser, A. ; McDermott, U. ; Döhner, K. ; Schlenk, R. F. ; Döhner, H. ; Campbell, P. J.
Personally tailored cancer management based on knowledge banks of genomic and clinical data
[10.1101/057497] BibTeX | EndNote: XML, Text | RIS

Journal Article Nik-Zainal, S. ; Davies, H. ; Staaf, J. ; et al
Landscape of somatic mutations in 560 breast cancer whole-genome sequences.
Nature <London> 534(7605), 47 - 54 (2016) [10.1038/nature17676]2016 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Papaemmanuil, E. ; Gerstung, M.Extern* ; Bullinger, L. ; Gaidzik, V. I. ; Paschka, P. ; Roberts, N. D. ; Potter, N. E. ; Heuser, M. ; Thol, F. ; Bolli, N. ; Gundem, G. ; Van Loo, P. ; Martincorena, I. ; Ganly, P. ; Mudie, L. ; McLaren, S. ; O?Meara, S. ; Raine, K. ; Jones, D. R. ; Teague, J. W. ; Butler, A. P. ; Greaves, M. F. ; Ganser, A. ; Döhner, K. ; Schlenk, R. F. ; Döhner, H. ; Campbell, P. J.
Genomic Classification and Prognosis in Acute Myeloid Leukemia
The New England journal of medicine 374(23), 2209 - 2221 (2016) [10.1056/NEJMoa1516192]2016 BibTeX | EndNote: XML, Text | RIS

Journal Article Hauri, S. ; Comoglio, F. ; Seimiya, M. ; Gerstung, M.Extern* ; Glatter, T. ; Hansen, K. ; Aebersold, R. ; Paro, R. ; Gstaiger, M. ; Beisel, C.
A High-Density Map for Navigating the Human Polycomb Complexome.
Cell reports 17(2), 583 - 595 (2016) [10.1016/j.celrep.2016.08.096]2016 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Gaidzik, V. I. ; Teleanu, V. ; Papaemmanuil, E. ; Weber, D. ; Paschka, P. ; Hahn, J. ; Wallrabenstein, T. ; Kolbinger, B. ; Köhne, C. H. ; Horst, H. A. ; Brossart, P. ; Held, G. ; Kündgen, A. ; Ringhoffer, M. ; Götze, K. ; Rummel, M. ; Gerstung, M.Extern* ; Campbell, P. ; Kraus, J. M. ; Kestler, H. A. ; Thol, F. ; Heuser, M. ; Schlegelberger, B. ; Ganser, A. ; Bullinger, L. ; Schlenk, R. F. ; Döhner, K. ; Döhner, H.
RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features
Leukemia 30(11), 2160 - 2168 (2016) [10.1038/leu.2016.126]2016 BibTeX | EndNote: XML, Text | RIS

Journal Article (Erratum/Correction) Gaidzik, V. I. ; Teleanu, V. ; Papaemmanuil, E. ; Weber, D. ; Paschka, P. ; Hahn, J. ; Wallrabenstein, T. ; Kolbinger, B. ; Köhne, C. H. ; Horst, H. A. ; Brossart, P. ; Held, G. ; Kündgen, A. ; Ringhoffer, M. ; Götze, K. ; Rummel, M. ; Gerstung, M.Extern* ; Campbell, P. ; Kraus, J. M. ; Kestler, H. A. ; Thol, F. ; Heuser, M. ; Schlegelberger, B. ; Ganser, A. ; Bullinger, L. ; Schlenk, R. F. ; Döhner, K. ; Döhner, H.
Erratum: RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features
Leukemia 30(11), 2282 - 2282 (2016) [10.1038/leu.2016.207]2016 BibTeX | EndNote: XML, Text | RIS

Journal Article Gerstung, M.Extern* ; Pellagatti, A. ; Malcovati, L. ; Giagounidis, A. ; Porta, M. G. D. ; Jädersten, M. ; Dolatshad, H. ; Verma, A. ; Cross, N. C. P. ; Vyas, P. ; Killick, S. ; Hellström-Lindberg, E. ; Cazzola, M. ; Papaemmanuil, E. ; Campbell, P. J. ; Boultwood, J.
Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes
Nature Communications 6(1), 5901 (2015) [10.1038/ncomms6901]2015 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Beerenwinkel, N. ; Schwarz, R. F. ; Gerstung, M.Extern* ; Markowetz, F.
Cancer evolution: mathematical models and computational inference.
Systematic biology 64(1), e1 - e25 (2015) [10.1093/sysbio/syu081]2015 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article (Letter) Shlien, A. ; Campbell, B. B. ; de Borja, R. ; et al
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers
Nature genetics 47(3), 257 - 262 (2015) [10.1038/ng.3202]2015 BibTeX | EndNote: XML, Text | RIS

Journal Article Martincorena, I. ; Roshan, A. ; Gerstung, M.Extern* ; Ellis, P. ; Van Loo, P. ; McLaren, S. ; Wedge, D. C. ; Fullam, A. ; Alexandrov, L. B. ; Tubio, J. M. ; Stebbings, L. ; Menzies, A. ; Widaa, S. ; Stratton, M. R. ; Jones, P. H. ; Campbell, P. J.
Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin.
Science / Science now 348(6237), 880 - 886 (2015) [10.1126/science.aaa6806]2015 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Ju, Y. S. ; Tubio, J. M. C. ; Mifsud, W. ; et al
Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells.
Genome research 25(6), 814 - 824 (2015) [10.1101/gr.190470.115]2015 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Yates, L. R. ; Gerstung, M.Extern* ; Knappskog, S. ; Desmedt, C. ; Gundem, G. ; Van Loo, P. ; Aas, T. ; Alexandrov, L. B. ; Larsimont, D. ; Davies, H. ; Li, Y. ; Ju, Y. S. ; Ramakrishna, M. ; Haugland, H. K. ; Lilleng, P. K. ; Nik-Zainal, S. ; McLaren, S. ; Butler, A. ; Martin, S. ; Glodzik, D. ; Menzies, A. ; Raine, K. ; Hinton, J. ; Jones, D. ; Mudie, L. J. ; Jiang, B. ; Vincent, D. ; Greene-Colozzi, A. ; Adnet, P.-Y. ; Fatima, A. ; Maetens, M. ; Ignatiadis, M. ; Stratton, M. R. ; Sotiriou, C. ; Richardson, A. L. ; Lønning, P. E. ; Wedge, D. C. ; Campbell, P. J.
Subclonal diversification of primary breast cancer revealed by multiregion sequencing.
Nature medicine 21(7), 751 - 759 (2015) [10.1038/nm.3886]2015 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Gerstung, M.Extern* ; Papaemmanuil, E. ; Campbell, P. J.
Subclonal variant calling with multiple samples and prior knowledge.
Bioinformatics 30(9), 1198 - 1204 (2014) [10.1093/bioinformatics/btt750]2014 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Tubio, J. M. C. ; Li, Y. ; Ju, Y. S. ; et al
Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.
Science / Science now 345(6196), 1251343 (2014) [10.1126/science.1251343]2014 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Ju, Y. S. ; Alexandrov, L. B. ; Gerstung, M.Extern* ; et al
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.
eLife 3, e02935 (2014) [10.7554/eLife.02935]2014 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Kawamura, S. ; Gerstung, M.Extern* ; Colozo, A. T. ; Helenius, J. ; Maeda, A. ; Beerenwinkel, N. ; Park, P. S. ; Müller, D. J.
Kinetic, energetic, and mechanical differences between dark-state rhodopsin and opsin.
Structure 21(3), 426 - 437 (2013) [10.1016/j.str.2013.01.011]2013 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Papaemmanuil, E. ; Gerstung, M.Extern* ; Malcovati, L. ; Tauro, S. ; Gundem, G. ; Van Loo, P. ; Yoon, C. J. ; Ellis, P. ; Wedge, D. C. ; Pellagatti, A. ; Shlien, A. ; Groves, M. J. ; Forbes, S. A. ; Raine, K. ; Hinton, J. ; Mudie, L. J. ; McLaren, S. ; Hardy, C. ; Latimer, C. ; Della Porta, M. G. ; O'Meara, S. ; Ambaglio, I. ; Galli, A. ; Butler, A. P. ; Walldin, G. ; Teague, J. W. ; Quek, L. ; Sternberg, A. ; Gambacorti-Passerini, C. ; Cross, N. C. P. ; Green, A. R. ; Boultwood, J. ; Vyas, P. ; Hellstrom-Lindberg, E. ; Bowen, D. ; Cazzola, M. ; Stratton, M. R. ; Campbell, P. J. ; Consortium, C. M. D. W. G. o. t. I. C. G. (Collaboration Author)
Clinical and biological implications of driver mutations in myelodysplastic syndromes.
Blood 122(22), 3616 - 3627 (2013) [10.1182/blood-2013-08-518886]2013 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Kockmann, T. ; Gerstung, M.Extern* ; Schlumpf, T. ; Xhinzhou, Z. ; Hess, D. ; Beerenwinkel, N. ; Beisel, C. ; Paro, R.
The BET protein FSH functionally interacts with ASH1 to orchestrate global gene activity in Drosophila.
Genome biology 14(2), R18 (2013) [10.1186/gb-2013-14-2-r18]2013 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Ambatipudi, S. ; Gerstung, M.Extern* ; Pandey, M. ; Samant, T. ; Patil, A. ; Kane, S. ; Desai, R. S. ; Schäffer, A. A. ; Beerenwinkel, N. ; Mahimkar, M. B.
Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers.
Genes, chromosomes & cancer 51(2), 161 - 173 (2012) [10.1002/gcc.20940]2012 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Gerstung, M.Extern* ; Beisel, C. ; Rechsteiner, M. ; Wild, P. ; Schraml, P. ; Moch, H. ; Beerenwinkel, N.
Reliable detection of subclonal single-nucleotide variants in tumour cell populations.
Nature Communications 3(1), 811 (2012) [10.1038/ncomms1814]2012 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Enderle, D. ; Beisel, C. ; Stadler, M. B. ; Gerstung, M.Extern* ; Athri, P. ; Paro, R.
Polycomb preferentially targets stalled promoters of coding and noncoding transcripts.
Genome research 21(2), 216 - 226 (2011) [10.1101/gr.114348.110]2011 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Pathare, S. M. ; Gerstung, M.Extern* ; Beerenwinkel, N. ; Schäffer, A. A. ; Kannan, S. ; Pai, P. ; Pathak, K. A. ; Borges, A. M. ; Mahimkar, M. B.
Clinicopathological and prognostic implications of genetic alterations in oral cancers.
Oncology letters 2(3), 445 - 451 (2011) [10.3892/ol.2011.271]2011 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Gerstung, M.Extern* ; Nakhoul, H. ; Beerenwinkel, N.
Evolutionary Games with Affine Fitness Functions: Applications to Cancer
Dynamic games and applications 1(3), 370 - 385 (2011) [10.1007/s13235-011-0029-0]2011 BibTeX | EndNote: XML, Text | RIS

Journal Article Gerstung, M.Extern* ; Eriksson, N. ; Lin, J. ; Vogelstein, B. ; Beerenwinkel, N.
The temporal order of genetic and pathway alterations in tumorigenesis.
PLOS ONE 6(11), e27136 (2011) [10.1371/journal.pone.0027136]2011 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Ambatipudi, S. ; Gerstung, M.Extern* ; Gowda, R. ; Pai, P. ; Borges, A. M. ; Schäffer, A. A. ; Beerenwinkel, N. ; Mahimkar, M. B.
Genomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome.
PLOS ONE 6(2), e17250 (2011) [10.1371/journal.pone.0017250]2011 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Gerstung, M.Extern* ; BEERENWINKEL, N.
Waiting Time Models of Cancer Progression
Mathematical population studies 17(3), 115 - 135 (2010) [10.1080/08898480.2010.490994]2010 BibTeX | EndNote: XML, Text | RIS

Journal Article Gerstung, M.Extern* ; Timmer, J. ; Fleck, C.
Noisy signaling through promoter logic gates.
Physical review / E 79(1 Pt 1), 011923 (2009) [10.1103/PhysRevE.79.011923]2009 BibTeX | EndNote: XML, Text | RIS

Journal Article Gerstung, M.Extern* ; Baudis, M. ; Moch, H. ; Beerenwinkel, N.
Quantifying cancer progression with conjunctive Bayesian networks.
Bioinformatics 25(21), 2809 - 2815 (2009) [10.1093/bioinformatics/btp505]2009 pmc Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Geier, F. ; Lohmann, J. U. ; Gerstung, M.Extern* ; Maier, A. T. ; Timmer, J. ; Fleck, C.
A quantitative and dynamic model for plant stem cell regulation.
PLOS ONE 3(10), e3553 (2008) [10.1371/journal.pone.0003553]2008 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Anastasiou, E. ; Kenz, S. ; Gerstung, M.Extern* ; MacLean, D. ; Timmer, J. ; Fleck, C. ; Lenhard, M.
Control of plant organ size by KLUH/CYP78A5-dependent intercellular signaling.
Developmental cell 13(6), 843 - 856 (2007) [10.1016/j.devcel.2007.10.001]2007 BibTeX | EndNote: XML, Text | RIS

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