Dr. Stefan Dentro
Journal Article
Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium.
Nature genetics nn, nn (2024) [10.1038/s41588-024-01875-8]
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Journal Article
The history of chromosomal instability in genome doubled tumors.
Cancer discovery 14(10), 1810-1822 (2024) [10.1158/2159-8290.CD-23-1249]
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Journal Article
Single-cell and spatial transcriptomics analysis of non-small cell lung cancer.
Nature Communications 15(1), 4388 (2024) [10.1038/s41467-024-48700-8]
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Journal Article
AmplificationTimeR: An R Package for Timing Sequential Amplification Events.
Bioinformatics 40(6), btae281 (2024) [10.1093/bioinformatics/btae281]
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Journal Article
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth
Nature genetics 55(2), 232-245 (2023) [10.1038/s41588-022-01280-z]
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Journal Article (Erratum/Correction)
Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
Nature Communications 13(1), 7567 (2022) [10.1038/s41467-022-32336-7]
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Journal Article
Spatial genomics maps the structure, nature and evolution of cancer clones.
Nature <London> 611(7936), 594 - 602 (2022) [10.1038/s41586-022-05425-2]
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Preprint
p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition
[10.1101/2022.02.03.478951]
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Journal Article
Biallelic mutations in cancer genomes reveal local mutational determinants.
Nature genetics 54(2), 128 - 133 (2022) [10.1038/s41588-021-01005-8]
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Journal Article
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
Cell 184(8), 2239 - 2254.e39 (2021) [10.1016/j.cell.2021.03.009]
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Preprint
Notch1 mutation drives clonal expansion in normal esophageal epithelium but impairs tumor growth
[10.1101/2021.06.18.448956]
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Preprint
Spatial genomics maps the structure, character and evolution of cancer clones
[10.1101/2021.04.16.439912]
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Journal Article
Mutant clones in normal epithelium outcompete and eliminate emerging tumours.
Nature <London> 598(7881), 510 - 514 (2021) [10.1038/s41586-021-03965-7]
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Journal Article
Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site.
Cancer discovery 11(2), 340 - 361 (2021) [10.1158/2159-8290.CD-20-1092]
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Journal Article
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival.
Nature Communications 12(1), 4496 (2021) [10.1038/s41467-021-24677-6]
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Journal Article
Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes.
Nature Communications 12(1), 6946 (2021) [10.1038/s41467-021-27079-w]
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Journal Article
Sex differences in oncogenic mutational processes
Nature Communications 11(1), 4330 (2020) [10.1038/s41467-020-17359-2]
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Journal Article
A community effort to create standards for evaluating tumor subclonal reconstruction.
Nature biotechnology 38(1), 97 - 107 (2020) [10.1038/s41587-019-0364-z]
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Journal Article
The mutational landscape of normal human endometrial epithelium.
Nature <London> 580(7805), 640 - 646 (2020) [10.1038/s41586-020-2214-z]
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Journal Article
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium.
Nature genetics 52(6), 604 - 614 (2020) [10.1038/s41588-020-0624-3]
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Journal Article
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Nature Communications 11(1), 4748 (2020) [10.1038/s41467-020-18151-y]
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Journal Article
Pervasive chromosomal instability and karyotype order in tumour evolution.
Nature <London> 587(7832), 126-132 (2020) [10.1038/s41586-020-2698-6]
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Journal Article
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition.
Nature genetics 52(3), 306-319 (2020) [10.1038/s41588-019-0562-0]
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Preprint
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
[10.1101/312041]
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Journal Article (Letter)
Neutral tumor evolution?
Nature genetics 50(12), 1630 - 1633 (2018) [10.1038/s41588-018-0258-x]
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Journal Article
Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets.
Nature genetics 50(5), 682 - 692 (2018) [10.1038/s41588-018-0086-z]
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Preprint
Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours
[10.1101/179705]
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Journal Article
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.
Nature <London> 545(7655), 446 - 451 (2017) [10.1038/nature22364]
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Journal Article
Genomic analysis and clinical management of adolescent cutaneous melanoma.
Pigment cell & melanoma research 30(3), 307 - 316 (2017) [10.1111/pcmr.12574]
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Journal Article
Tracking the Evolution of Non-Small-Cell Lung Cancer.
The New England journal of medicine 376(22), 2109 - 2121 (2017) [10.1056/NEJMoa1616288]
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Journal Article
Principles of Reconstructing the Subclonal Architecture of Cancers.
Cold Spring Harbor perspectives in medicine 7(8), a026625 - (2017) [10.1101/cshperspect.a026625]
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Journal Article
Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters.
Annals of oncology 28(10), 2472 - 2480 (2017) [10.1093/annonc/mdx355]
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Journal Article
Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
Cell 171(6), 1259 - 1271.e11 (2017) [10.1016/j.cell.2017.10.001]
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Journal Article
The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma.
Cancer research 76(17), 5092 - 5102 (2016) [10.1158/0008-5472.CAN-16-0658]
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Journal Article
Diagnosis of fanconi anemia: mutation analysis by next-generation sequencing.
Anemia 2012, 1 - 7 (2012) [10.1155/2012/132856]
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