Original- und Übersichtsarbeiten im Jahr 2017 und im Druck
Taylor AE, Martin RM, Geybels MS, Stanford JL, Shui I, Eeles R, Easton DF, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pashayan N, Khaw KT, Blot W, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, and the PRACTIAL Consortium, Donovan J, Munafò MR.
Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis.
International Journal of Cancer 2017; 140:322-328.
Brunner C, Davies NM, Martin RM, Eeles R, Easton DF,…, Brenner H,…, Teixeira MR, Pandha H, the PRACTICAL Consortium, Zuccolo L.
Alcohol consumption and prostate cancer incidence and progression: a Mendelian randomization study.
International Journal of Cancer 2017; 140:75-85.
Maierthaler M, Benner A, Hoffmeister M, Surowy H, Jansen L, Knebel P, Chang-Claude J, Brenner H, Burwinkel B.
Plasma miR-122 and miR-200 family are prognostic markers in colorectal cancer.
International Journal of Cancer 2017; 140:176-187.
Weischenfeldt J, Dubash T, Drainas A, Mardin B, Chen Y, Stuetz A, Waszak S, Bosco G, Halvorsen AR, Raeder B, Efthymiopoulos T, Brenner H, Brustugun OT, Dieter S, Northcott P, Petersen I, Pfister S, Schneider M, Solberg S, Thunnissen E, Weichert W, Zichner T, Thomas R, Peifer M, Helland A, Ball C, Jechlinger M, Sotillo R, Glimm H, Siegl C, Korbel J.
Pan-cancer analysis of somatic copy number alterations implicates IRS4 and IGF2 in enhancer hijacking.
Nature Genetics 2017; 49:65-74.
Heiss JA, Breitling LP, Lehne B, Kooner JS, Chambers JC, Brenner H.
Training a model for estimating leukocyte composition using whole blood DNA methylation and cell counts as reference.
Epigenomics 2017; 9:13-20.
Jankovic N, Geelen A, Winkels RM, Mwungura B, Fedirko V, Jenab M, Illner AK, Brenner H, Ordonez-Mena JM, Kiefte-de Jong JC, Franco OH, Orfanos P, Trichopoulou A, Boffetta P, Agudo A, Peeters PH, Tjonneland A, Hallmans G, Bueno-de-Mesquita HB, Park Y, Feskens EJ, de Groot LC, Kampman E.
Adherence to the WCRF/AICR dietary recommendations for cancer prevention and risk of cancer in elderly from Europe and the United States: A Meta-Analysis within the CHANCES project.
Cancer Epidemiology, Biomarkers and Prevention 2017; 26:136-144.
Skender S, Böhm J, Schrotz-King P, Chang-Claude J, Siegel EM, Steindorf K, Owen RW, Ose J, Hoffmeister M, Brenner H, Ulrich CM.
Plasma 25-hydroxyvitamin D3 levels in colorectal cancer patients and associations with physical activity.
Nutrition and Cancer 2017; 69:229-237.
Zhang Y, Hapala J, Brenner H, Wagner W.
Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging.
Clinical Epigenetics 2017; 9:9.
Logan CA, Bornemann R, König W, Reister F, Walter V, Fantuzzi G, Weyermann M, Brenner H, Genuneit J, Rothenbacher D.
Gestational weight gain and fetal-maternal adiponectin, leptin, and CRP: results of two birth cohorts studies.
Scientific Reports 2017; 7:41847.
Hoffmeister M, Holleczek B, Zwink N, Stock C, Stegmaier C, Brenner H.
Darmkrebsscreening – Steigerung der Teilnahmeraten durch persönliche Einladung.
Eine randomisierte Interventionsstudie.
Deutsches Ärzteblatt International 2017; 114:87-93.
Brenner H, Zwink N, Ludwig L, Hoffmeister M.
Should screening colonoscopy be offered from age 50? Results from a statewide pilot project, and from a randomized intervention study.
Deutsches Ärzteblatt International 2017; 114:94-100.
Pulte D, Castro FA, Brenner H, Jansen L.
Outcome disparities by insurance type for patients with acute myeloblastic leukemia.
Leukemia Research 2017; 56: 75-81.
Katsoulis M, Benetou V, Karapetyan T, Feskanich D, Grodstein F, Kymmer U, Eriksson S, Wilsgaard T, Jorgensen L, Ahmed L, Schöttker B, Brenner H, Bellavia A, Wolk A, Kubinova R, Stegeman B, Bobak M, Boffetta P, Trichopoulou A.
Excess mortality after hip fractures in elderly from Europe and United States: the CHANCES project.
Journal of Internal Medicine 2017; 281:300-310.
Muhlack DC, Hoppe LK, Weberpals J, Brenner H, Schöttker B.
Association of potentially inappropriate medication at older age with cardiovascular events and overall mortality: a systematic review and meta-analysis of cohort studies.
Journal of the American Medical Directors Association 2017; 18:211-220.
Arndt V, Koch-Gallenkamp L, Jansen L, Bertram H, Eberle A, Holleczek B, Schmid-Höpfner S, Waldmann A, Zeissig SR, Brenner H.
Quality of life in long-term and very long-term cancer survivors versus population controls in Germany.
Acta Oncologica 2017; 56:190-197.
Saum KU, Schöttker B, Meid A, Holleczek B, Haefeli W, Hauer K, Brenner H.
Is polypharmacy associated with frailty in older people? Results from the ESTHER Cohort Study.
Journal of the American Geriatrics Society 2017; 65:e27-e32.
Gao X, Zhang Y, Saum KU, Schöttker B, Breitling LP, Brenner H.
Tobacco smoking and smoking-related DNA methylation are associated with the development of frailty among older adults.
Epigenetics 2017; 12:149-156.
Wieland E, Rodriguez-Vita J, Liebler SS, Mogler C, Moll I, Herberich SE, Espinet E, Herpel E, Menuchin A, Chang-Claude J, Hoffmeister M, Gebhardt C, Brenner H, Trumpp A, Siebel CW, Hecker M, Utikal J, Sprinzak D, Fischer A.
Endothelial Notch1 activity facilitates metastasis.
Cancer Cell 2017; 31:355-367.
Heiss JA, Brenner H.
Epigenome-wide discovery and evaluation of leukocyte DNA methylation markers for the detection of colorectal cancer in a screening setting.
Clinical Epigenetics 2017; 9:24.
Brenner H, Niedermaier T, Chen H.
Strong subsite-specific variation in detecting advanced adenomas by fecal immunochemical testing for hemoglobin.
International Journal of Cancer 2017; 140:2015-2022.
Pulte D, Jansen L, Brenner H.
Population level differences in rectal cancer survival in uninsured patients are partially explained by differences in treatment.
The Oncologist 2017; 22:351-358.
Fehringer G, Brenner DR, Zhang ZF, Lee YCA, Matsuo K,…, Brenner H,…, Consonni D, Olsson A, Straif K, Hung RJ.
Alcohol and lung cancer risk among never smokers: a pooled analysis from the International Lung Cancer Consortium and the SYNERGY study.
International Journal of Cancer 2017; 140:1976-1984.
Walter V, Jansen L, Knebel P, Chang-Claude J, Hoffmeister M, Brenner H.
Physical activity and survival of colorectal cancer patients: population-based study from Germany.
International Journal of Cancer 2017; 140:1985-1997.
Hajek A, Bock J-O, Brenner H, Saum K-U, Matschinger H, Haefeli WE, Quinzler R, Heider D, König H-H.
Welche Faktoren beeinflussen die privaten Zuzahlungen zu Gesundheitsleistungen im Alter? Ergebnisse einer Längsschnittstudie.
Das Gesundheitswesen 2017; 79:e18-e25.
Breitling LP, Mons U, Hahmann H, König W, Rothenbacher D, Brenner H.
The longer, the better? An empirical study of the extent and mechanisms of attenuating biomarker associations in cardiovascular patient cohorts.
Clinical Chemistry 2017; 63:673-682.
Zwink N, Stock C, Birkner B, Hoffmeister M, Brenner H.
Screening colonoscopy volume and detection of colorectal neoplasms: A state-wide study from Bavaria, Germany.
European Journal of Cancer Prevention 2017; 26:181-188.
Brenner H, Weberpals J, Jansen L.
Epidemiologische Forschung mit Krebsregisterdaten, Überlebenszeitanalysen, Vergleich nationaler und internationaler Ergebnisse.
Der Onkologe 2017; 23:272-279.
Zwink N, Stock C, Birkner B, Hoffmeister M, Brenner H.
Screening colonoscopy volume and detection of colorectal neoplasms: A state-wide study from Bavaria, Germany.
European Journal of Cancer Prevention 2017; 26:181-188.
Berendsen A, Kang J, van de Rest O, Jankovic N, Kampman E, Kiefte-deJong J, Franco O, Ikram A, Pikhart H, Nilsson L, Brenner H, Boffetta P, Rafnsson S, Gustafson D, Kyrozis A, Trichopoulou A, Feskens E, Grodstein F, de Groot L.
Association of adherence to a healthy diet with cognitive decline in European and American older adults: a meta-analysis within the CHANCES consortium.
Dementia and Geriatric Cognitive Disorders 2017; 43:215-227.
Zhang Y, Wilson R, Heiss J, Breitling LP, Saum KU, Schöttker B, Holleczek B, Waldenberger M, Peters A, Brenner H.
DNA methylation signatures in peripheral blood strongly predict all-cause mortality.
Nature Communications 2017; 8:14617.
Zuber V, Bettella F, Witoelar A, PRACTICAL Consortium*, CRUK GWAS, BCAC Consortium, TRICL Consortium, Andreassen OA, Mills IG, Urbanucci A.
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer.
BMC Genomics 2017; 18:270.
*Collaborator from DKFZ: Brenner H
Steele CJ, Schöttker B, Marshall AH, Kouvonen A, O’Doherty MG, Mons U, Saum KU, Boffetta P, Trichopoulou A, Brenner H*, Kee F*.
Education achievement and type 2 diabetes – What mediates the relationship in older adults? Data from the ESTHER study: a population-based cohort study.
BMJ Open 2017; 0:e013569.
*shared last authorship
Dal Maso L, Tavilla A, Pacini F, Serraino D, van Dijk BAC, Chirlaque MD, Capocaccia R, Larrañaga N, Colonna M, Agius D, Ardanaz E, Rubió-Casadevall J, Kowalska A, Virdone S, Mallone S, Amash H, De Angelis R, EUROCARE-5 Working Group*.
Survival of 86,690 patients with thyroid cancer: A population-based study in 29 European countries from EUROCARE-5.
European Journal of Cancer 2017; 77:140-152.
*Collaborator from DKFZ: Brenner H
Pulte D, Jansen L, Brenner H.
Social disparities in survival after diagnosis with colorectal cancer: contribution of race and insurance status.
Cancer Epidemiology 2017; 48:41-47.
Fagerholm R, Khan S, Schmidt MK, García-Closas M, Heikkilä P,…, Brenner H,…, Pharoah PDP, Chenevix-Trench G, Blomqvist C, Nevanlinna H.
TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer.
Oncotarget 2017; 8:18381-18398.
Mayer T, Meid AD, Saum KU, Brenner H, Schöttker B, Seidling HM, Haefeli WE.
Comparison of nine instruments to calculate anticholinergic load in a large cohort of older outpatients: association with cognitive and functional decline, falls, and use of laxatives.
American Journal of Geriatric Psychiatry 2017; 25:531-540.
NCD Risk Factor Collaboration (NCD-RisC)*.
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1,479 population-based measurement studies with 19.1 million participants.
The Lancet 2017; 389:37-55.
*Collaborators on behalf of the ESTHER study: Brenner H, Saum KU.
Ordóñez-Mena JM, Maalmi H, Schöttker B, Saum KU, Holleczek B, Wang TJ, Burwinkel B, Brenner H.
Genetic variants in the vitamin D pathway, 25(OH)D levels, and mortality in a large population-based cohort study.
Journal of Clinical Endocrinology & Metabolism 2017; 102:470-477.
Global Burden of Disease Cancer Collaboration*.
Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 Cancer Groups, 1990 to 2015: a systematic analysis for the Global Burden of Disease Study.
JAMA Oncology 2017; 3:524-548.
*Collaborator from DKFZ: Brenner H
Winter A, Sirri E, Jansen L, Wawroschek F, Kieschke J, Castro FA, Krilaviciute A, Holleczek B, Emrich K, Waldmann A, Brenner H, for the Association for Population-based Cancer Registries in Germany (GEKID) Cancer Survival Working Group.
Comparison of prostate cancer survival in Germany and the USA: can differences be attributed to differences in stage distributions?
BJU International 2017; 119:550-559.
Sluik D, Jankovic N, Hughes M, O’Doherty MG, Schöttker B,…, Brenner H,…, Iacoviello L, Boffetta P, Kee F, Feskens EJM.
Alcoholic beverage preference and diabetes incidence across Europe: the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) project.
European Journal of Clinical Nutrition 2017; 71:659-668.
Lin HY, Chen DT, Huang PY, Liu YH, Ochoa A,…, Brenner H,…, Pandha H, Lu YJ, the PRACTICAL consortium, Park JY.
SNP interaction pattern identifier (SIPI): An intensive search for SNP-SNP interaction patterns.
Bioinformatics 2017; 33:822-833.
Zwink N, Holleczek B, Stegmaier C, Hoffmeister M, Brenner H.
Complication rates in colonoscopy screening for cancer – a prospective cohort study of complications arising during the procedure and in the ensuing four weeks.
Deutsches Ärzteblatt International 2017; 114:321-327.
Freisling H, Arnold M, Soerjomataram I, O’Doherty M, Ordóñez-Mena J, Bamia C, Kampman E, Leitzmann M, Romieu I, Kee F, Tsilidis K, Tjonneland A, Trichopoulou A, Boffetta P, Benetou V, Bueno-de-Mesquita HB, Huerta JM, Brenner H, Wilsgaard T, Jenab M.
Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk: meta-analysis of individual participant data of seven prospective cohorts in Europe.
British Journal of Cancer 2017; 116:1486-1497.
Ben Khedher S, Neri M, Papadopoulos A, Christiani DC, Diao N, Harris CC, Olivo-Marston S, Schwartz AG, Cote M, Koushik A, Siemiatycki J, Landi MT, Hung RJ, McLaughlin J, Duell EJ, Andrew AS, Orlow I, Park BJ, Brenner H, Saum KU, Pesatori AC, Stücker I.
Menstrual and reproductive factors and lung cancer risk: A pooled analysis from the International Lung Cancer Consortium (ILCCO).
International Journal of Cancer 2017; 141:309-323.
Day FR, Thompson DJ, Helgason H, Chasman DI, Finucane H,…, Brenner H,..., Murabito JM, Stefansson K, Ong KK, Perry JRB.
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.
Nature Genetics 2017; 49:834-841.
Bonaventure A, Harewood R, Stiller CA, Gatta G, Clavel J, Stefan DC, Carreira H, Spika D, Marcos-Gragera R, Peris-Bonet R, Pineros M, Sant M, Kuehni CE, Murphy MFG, Coleman MP, Allemani C, CONCORD Working Group*.
Worldwide comparison of survival from childhood leukaemia for 1995-2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual data for 89 828 children from 198 registries in 53 countries.
Lancet Haematology 2017; 4:e202-e217.
*Collaborator from DKFZ: Brenner H
GBD 2015 Tobacco Collaborators.*
Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: a systematic analysis from the Global Burden of Disease Study 2015.
The Lancet 2017; 389:1885-1906.
*Collaborators from DKFZ: Brenner H, Schöttker B
Jansen L*, Weberpals J*, Kuiper JG, Vissers PAJ, Wolkewitz M, Hoffmeister M, Brenner H.
Pre- and post-diagnostic beta-blocker use and prognosis after colorectal cancer: Results from a population-based study.
International Journal of Cancer 2017; 141:62-71.
*Contributed equally
Muranen TA, Greco D, Blomqvist C, Aittomäki K, Khan S,…, Brenner H, Arndt V,…, Dennis J, Easton DF, Schmidt MK, Nevanlinna H.
Genetic modifiers of CHEK2*1100delC associated breast cancer risk.
Genetics in Medicine 2017; 19:599-603.
Weberpals J, Jansen L, Haefeli WE, Hoffmeister M, Wolkewitz M, van Herk-Sukel M, Vissers PAJ, Brenner H.
Pre- and post-diagnostic β-blocker use and lung cancer survival: A population-based cohort study.
Scientific Reports 2017; 7:2911.
Heiss JA, Brenner H.
Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with common risk factors.
Epigenomics 2017; 9:659-668.
Carr P, Holleczek B, Stegmaier C, Brenner H, Hoffmeister M.
Meat intake and risk of colorectal polyps: results from a large population based screening study in Germany.
American Journal of Clinical Nutrition 2017; 105:1453-1461.
Weberpals J*, Pulte D*, Jansen L, Luttmann S, Holleczek B, Nennecke A, Ressing M, Katalinic A, Merz M, Brenner H, for the GEKID Cancer Survival Working Group.
Survival of patients with lymphoplasmacytic lymphoma and solitary plasmacytoma in Germany and the United States in the early 21st century.
Haematologica 2017; 102:e229-e232.
*Contributed equally to the paper
Shimelis H, Mesman RLS, Von Nicolai C, Ehlen A, Guidugli L,…, Arndt V,…, Brenner H,…, Goldgar DE, Carreira A, Vreeswijk MPG, Couch FJ.
BRCA2 hypomorphic missense variants confer moderate risks of breast cancer.
Cancer Research 2017; 77:2789-2799.
Arnold A, Kloor M, Jansen L, Chang-Claude J, Brenner H, von Winterfeld M, Hoffmeister M, Bläker H.
The association between microsatellite instability and lymph node count in colorectal cancer.
Virchows Archiv 2017; 471:57-64.
Zewinger S, Kleber ME, Tragante V, McCubrey RO, Schmidt AF,…, Mons U, Brenner H,…, Fliser D, März W, Scharnagl H, Speer T.
Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.
Lancet Diabetes & Endocrinology 2017; 5:534-543.
Mons U, Brenner H.
Demographic ageing and the evolution of smoking-attributable mortality: the example of Germany.
Tobacco Control 2017; 26:455-457.
Pfetsch V, Sanin V, Jaensch A, Dallmeier D, Mons U, Brenner H, König W, Rothenbacher D.
Increased plasma concentrations of soluble ST2 independently predict mortality but not cardiovascular events in stable coronary heart disease patients: 13-year follow-up of the KAROLA study.
Cardiovascular Drugs and Therapy 2017; 31:167-177.
Brenner H, Chen H.
Fecal occult blood versus DNA testing: indirect comparison in a colorectal cancer screening population.
Clinical Epidemiology 2017; 9:377-384.
Gatta G, Peris-Bonet R, Visser O, Stiller C, Marcos-Gragera R, Sánchez MJ, Lacour B, Kaatsch P, Berrino F, Rutkowsky S, Botta L, and the EUROCARE-5 Working Group*.
Geographical variability in survival of European children with central nervous system tumours.
European Journal of Cancer 2017; 82:137-148.
*Collaborator from DKFZ: Brenner H
Reuter B, Sauer T, Gumbinger G, Bruder I, Preussler S, Hacke W, Hennerici MG, Ringleb PA, Kern R, Stock C.
Diurnal variation of intravenous thrombolysis rates for acute ischemic stroke and associated quality performance parameters.
Frontiers in Neurology 2017; 8:341.
Carr PR, Jansen L, Bienert S, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.
Associations of red and processed meat intake with major molecular pathological features of colorectal cancer.
European Journal of Epidemiology 2017; 32:409-418.
Schöttker B, Saum KU, Muhlack DC, Hoppe LK, Holleczek B, Brenner H.
Polypharmacy and mortality: new insights from a large cohort of older adults by detection of effect modification by multi-morbidity and comprehensive correction of confounding by indication.
European Journal of Clinical Pharmacology 2017; 73:1041-1048.
Brenner H, Jansen L, Saum KU, Holleczek B, Schöttker B.
Vitamin D supplementation trials aimed at reducing mortality have much higher power when focusing on people with low serum 25-hydroxyvitamin D concentrations.
Journal of Nutrition 2017; 147:1325-1333.
GBD 2015 Healthcare Access and Quality Collaborators.*
Healthcare access and quality index based on mortality from causes amenable to personal healthcare in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015.
Lancet 2017; 390:231-266.
*Collaborators from DKFZ: Brenner H, Schöttker B
Butt J, Werner S, Willhauck-Fleckenstein M, Michel A, Waterboer T, Zörnig I, Boleij A, Dramsi S, Brenner H, Pawlita M.
Serology of Streptococcus gallolyticus subspecies gallolyticus and its association with colorectal cancer and precursors.
International Journal of Cancer 2017; 141:897-904.
Gao X, Gào X, Zhang Y, Breitling LP, Schöttker B, Brenner H.
Associations of self-reported smoking, cotinine levels and epigenetic smoking indicators with oxidative stress among older adults: a population-based study.
European Journal of Epidemiology 2017; 32:443-456.
Thomas B, Matsushita K, Abate KH, Al-Aly Z, Ärnlöv J,…, Brenner H,…, Schöttker B,…, Vos T, Global Burden of Disease 2013 GFR Collaborators, CKD Prognosis Consortium, Global Burden of Disease Genitourinary Expert Group.
Global cardiovascular and renal outcomes of reduced GFR.
Journal of the American Society of Nephrology 2017; 28:2167-2179.
Chen C, Läcke E, Stock C, Hoffmeister M, Brenner H.
Colonoscopy and sigmoidoscopy use among older adults in different countries: a systematic review.
Preventive Medicine 2017; 103:33-42.
GBD 2016 Mortality Collaborators.*
Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016.
The Lancet 2017; 390:1084-1150.
*Collaborator from DKFZ: Brenner H
GBD 2016 Risk Factors Collaborators.*
Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.
The Lancet 2017; 390:1345-1422.
*Collaborator from DKFZ: Brenner H
Breitling LP, Mons U, Hahmann H, König W, Rothenbacher D, Brenner H.
Composite End Points: Implications of changing compositions with longer follow-up.
Circulation: Cardiovascular Quality and Outcomes 2017; 10:e003458.
Minicozzi P, Innos K, Sánchez MJ, Trama A, Walsh PM, Marcos-Gragera R, Dimitrova N, Botta L, Visser O, Rossi S, Tavilla A, Sant M, The EUROCARE-5 Working Group.*
Quality analysis of population-based information on cancer stage at diagnosis across Europe, with presentation of stage-specific cancer survival estimates: A EUROCARE-5 study.
European Journal of Cancer 2017; 84:335-353.
*Collaborator from DKFZ: Brenner H
Ordóñez-Mena JM, Schöttker B, Saum KU, Holleczek B, Burwinkel B, Wang TJ, Brenner H.
No association of vitamin D pathway genetic variants with cancer risks in a population-based cohort of German older adults.
Cancer Epidemiology, Biomarkers & Prevention 2017; 26:1459-1461.
Christiansen H, Brandt S, Walter V, Wabitsch M, Rothenbacher D, Brenner H, Schimmelmann BG, Hirsch O.
Prediction of BMI at age 11 in a longitudinal sample of the Ulm Birth Cohort Study.
PLoS ONE 2017; 12:e0182338.
Gao X, Thomsen H, Zhang Y, Breitling LP, Brenner H.
The impact of methylation quantitative trait loci (mQTLs) on active smoking-related DNA methylation changes.
Clinical Epigenetics 2017; 9:87.
Kirchberg FF, Brandt S, Moß A, Peissner W, König W, Rothenbacher D, Brenner H, Koletzko B, Hellmuth C*, Wabitsch M*.
Metabolomics reveals an entanglement of fasting leptin concentrations with fatty acid oxidation and gluconeogenesis in healthy children.
PLoS ONE 2017; 12:e0183185.
*Contributed equally
Pulte D, Weberpals J, Jansen L, Luttmann S, Holleczek B, Nennecke A, Ressing M, Katalinic A, Brenner H, GEKID Cancer Survival Working Group.
Survival for patients with rare hematologic malignancies: changes in the early 21st century.
European Journal of Cancer 2017; 84:81-87.
Bamia C, Orfanos P, Juerges H, Schöttker B, Brenner H, Lorbeer R, Aadahl M, Matthews CE, Klinaki E, Katsoulis M, Lagiou P, Bueno-de-Mesquita HBA, Eriksson S, Mons U, Saum KU, Kubinova R, Pajak A, Tamosiunas A, Malyutina S, Gardiner J, Peasey A, de Groot LC, Wilsgaard T, Boffetta P, Trichopoulou A, Trichopoulos D.
Self-rated health and all-cause and cause-specific mortality of older adults. Individual data meta-analysis of prospective cohort studies participating in the CHANCES Consortium.
Maturitas 2017; 103:37-44.
Brenner H, Werner S.
Selecting a cut-off for colorectal cancer screening with a fecal immunochemical test.
Clinical and Translational Gastroenterology 2017; 8:e111.
Lophatananon A, Stewart-Brown S, Kote-Jarai Z, Al Olama AA, Benlloch Garcia S, Neal DE, Hamdy FC, Donovan JL, Giles GG, Fitzgerald LM, Southey MC, Pharoah P, Pashayan N, Gronberg H, Wiklund F, Aly M, Stanford JL, Brenner H, Dieffenbach AK, Arndt V, Park JY, Lin HY, Sellers T, Slavov C, Kaneva R, Mitev V, Batra J, Spurdle A, Clements JA, APCB BioResource, The PRACTICAL consortium, Easton D, Eeles RA, Muir K.
Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium.
British Journal of Cancer 2017; 117:734-743.
Matsushita K, Ballew SH, Coresh J, Arima H, Ärnlöv J, Cirillo M, Ebert N, Hiramoto JS, Kimm H, Shlipak MG, Visseren FLJ, Gansevoort RT, Kovesdy CP, Shalev V, Woodward M, Kronenberg F, Chronic Kidney Disease Prognosis Consortium.
Measures of chronic kidney disease and risk of incident peripheral artery disease: a collaborative meta-analysis of individual participant data.
Lancet Diabetes & Endocrinology 2017; 5:718-728.
Collaborators from the ESTHER study: Brenner H, Schöttker B, Rothenbacher D, Saum KU
Krilaviciute A, Stock C, Brenner H.
International variation in the prevalence of preclinical colorectal cancer: implications for predictive values of noninvasive screening tests and potential target populations for screening.
International Journal of Cancer 2017; 141:1566-1575.
Amitay EL, Werner S, Vital M, Pieper DH, Höfler D, Gierse IJ, Butt J, Balavarca Y, Cuk K, Brenner H.
Fusobacterium and colorectal cancer: Causal factor or passenger? Results from a large colorectal cancer screening study.
Carcinogenesis 2017; 38:781-788.
Niedermaier T, Weigl K, Hoffmeister M, Brenner H.
Diagnostic performance of flexible sigmoidoscopy combined with fecal immunochemical test in colorectal cancer screening: meta-analysis & modeling.
European Journal of Epidemiology 2017; 32:481-493.
Meistere I, Werner S, Zayakin P, Siliņa K, Rulle U, Pismennaja A, Šantare D, Kikuste I, Isajevs S, Leja M, Kupčinskas L, Kupčinskas J, Jonaitis L, Wu CY, Brenner H, Linē A, Kalniņa Z.
The prevalence of cancer-associated autoantibodies in patients with gastric cancer and progressive grades of premalignant lesions.
Cancer Epidemiology, Biomarkers & Prevention 2017; 26:1564-1574.
Gu F, Zhang H, Hyland PL, Berndt S, Gapstur SM, Wheeler W, the ELLIPSE consortium, Amos CI, Bezieau S, Bickeböller H, Brenner H, Brennan P, Chang-Claude J, Conti DV, Doherty J, Gruber SB, Harrison TA, Hayes RB, Hoffmeister M, Houlston RS, Hung RJ, Jenkins MA, Kraft P, Lawrenson K, McKay J, Markt S, Mucci L, Phelan CM, Qu C, Risch A, Rossing MA, Wichmann HE, Shi J, Schernhammer E, Yu K, Landi MT, Caporaso NE.
Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia.
International Journal of Cancer 2017; 141:1794-1802.
Barrdahl M, Rudolph A, Hopper JL, Southey MC, Broeks A,…, Brenner H, Arndt V,…, Garcia-Closas M, Easton DF, Milne RL, Chang-Claude J.
Gene-environment interactions involving functional variants: results from the Breast Cancer Association Consortium.
International Journal of Cancer 2017; 141:1830-1840.
Logan CA, Brandt S, Wabitsch M, Brenner H, Wiens F, Stahl S, Marosvölgyi T, Decsi T, Rothenbacher D, Genuneit J.
New approach shows no association between maternal milk fatty acid composition and childhood wheeze or asthma.
Allergy 2017; 72:1374-1383.
Gao X, Zhang Y, Brenner H.
Associations of Helicobacter pylori infection and chronic atrophic gastritis with accelerated epigenetic ageing in older adults.
British Journal of Cancer 2017; 117:1211-1214.
Chen T, Brenner H, Fallah M, Jansen L, Castro FA, Geiss K, Holleczek B, Katalinic A, Luttmann S, Sundquist K, Ressing M, Xu L, Hemminki K, GEKID Cancer Survival Working Group.
Risk of second primary cancers in women diagnosed with endometrial cancer in German and Swedish cancer registries.
International Journal of Cancer 2017; 141:2270-2280.
Boehlen FH, Herzog W, Schellberg D, Maatouk I, Saum KU, Brenner H, Wild B.
Self-perceived coping resources of middle-aged and older adults – results of a large population-based study.
Aging and Mental Health 2017; 21:1303-1309.
Chen H, Werner S, Brenner H.
Fresh vs frozen samples and ambient temperature have little effect on detection of colorectal cancer or adenomas by a fecal immunochemical test in a colorectal cancer screening cohort in Germany.
Clinical Gastroenterology and Hepatology 2017; 15:1547-1556.
Maddock J, Zhou A, Cavadino A, Kuzma E, Bao Y,…, Brenner H, Kumari M, Power C, Llewellyn DJ, Hyppönen E.
Vitamin D and cognitive function: A mendelian randomisation study.
Scientific Reports 2017; 7:13230.
Mons U, Müezzinler A, Schöttker B, Dieffenbach AK, Butterbach K, Schick M, Peasey A, De Vivo I, Trichopoulou A, Boffetta P, Brenner H.
Leukocyte telomere length and all-cause, cardiovascular disease, and cancer mortality: Results from individual participant-data meta-analysis of two large prospective cohort studies.
American Journal of Epidemiology 2017; 185:1317-1326.
Barrow TM, Klett H, Toth R, Böhm J, Gigic B, Habermann N, Scherer D, Schrotz-King P, Skender S, Abbenhardt-Martin C, Zielske L, Schneider M, Ulrich A, Schirmacher P, Herpel E, Brenner H, Busch H, Boerries M, Ulrich CM, Michels KB.
Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study.
Journal of Pathology 2017; 243:366-375.
Dimitrakopoulou VI, Tsilidis KK, Haycock PC, Dimou NL, Al-Dabhani K,…, Brenner H,…, Hoffmeister M,…, the PRACTICAL Consortium, Kraft P, Pierce BL, Schildkraut JM, on behalf of GECCO, PRACTICAL and the GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI-OCAC and TRICL-ILCCO.
Circulating vitamin D concentration and risk of seven cancers: Mendelian randomization study.
The BMJ 2017; 359:j4761.
Michailidou K, Lindström S, Dennis J, Beesley J, Hui S,…, Arndt V,…, Brenner H,…, Chenevix-Trench G, Simard J, Kraft P, Easton DF.
Association analysis identifies 65 new breast cancer risk loci.
Nature 2017; 551:92-94.
Brouckaert O, Rudolph A, Laenen A, Keeman R, Bolla MK,…, Arndt V,…, Brenner H,…, Garcia-Closas M, Chang-Claude J, Lambrechts D, Neven P.
Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study.
Breast Cancer Research 2017; 19:119.
Maalmi H, Walter V, Jansen L, Chang-Claude J, Owen RW, Ulrich A, Schöttker B, Hoffmeister M, Brenner H.
Relationship of very low serum 25-hydroxyvitamin D3 levels with long-term survival in a large cohort of colorectal cancer patients from Germany.
European Journal of Epidemiology 2017; 32:961-971.
Weberpals J, Jansen L, van Herk-Sukel MPP, Kuiper JG, Aarts MJ, Vissers PAJ, Brenner H.
Immortal time bias in pharmacoepidemiological studies on cancer patient survival: empirical illustration for beta-blocker use in four cancers with different prognosis.
European Journal of Epidemiology 2017; 32:1019-1031.
Bhardwaj M, Erben V, Schrotz-King P, Brenner H.
Cell line secretome and tumor tissue proteome markers for early detection of colorectal cancer: a systematic review.
Cancers 2017; 9:156.
Bien SA, Auer PL, Harrison TA, Qu C, Conolly CM, Greenside PG, Chen S, Berndt SI, Bézieau S, Kang HM, Huyghe J, Brenner H, Casey G, Chan AT, Hopper JL, Banbury BL, Chang-Claude J, Chanock SJ, Haile RW, Hoffmeister M, Fuchsberger C, Jenkins MA, Leal SM, Lemire M, Newcomb PA, Gallinger S, Potter JD, Schoen RE, Slattery ML, Smith JD, Le Marchand L, White E, Zanke BW, Abecasis GR, Carlson CS, Peters U, Nickerson DA, Kundaje A, Hsu L, on behalf of GECCO and CCFR.
Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data.
PLoS ONE 2017; 12:e0186518.
Chen H, Qian J, Werner S, Cuk K, Knebel P, Brenner H.
Development and validation of a panel of five proteins as blood biomarkers for early detection of colorectal cancer.
Clinical Epidemiology 2017; 9:517-526.
Milne RL, Kuchenbaecker KB, Michailidou K, Beesley J, Kar S,…, Arndt V,…, Brenner H,…, Chenevix-Trench G, Garcia-Closas M, Schmidt MK, Antoniou AC, Simard J.
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.
Nature Genetics 2017; 49: 1767-1778.
Bozorgmehr K, Razum O, Szecsenyi J, Maier W, Stock C.
Regional deprivation is associated with the distribution of vulnerable asylum-seekers: a nation-wide small-area analysis in Germany.
Journal of Epidemiology & Community Health 2017; 71:857-862.
Bock JO, Hajek A, Brenner H, Saum KU, Matschinger H, Haefeli WE, Schöttker B, Quinzler R, Heider D, König HH.
A longitudinal investigation of willingness to pay for health insurance in Germany.
Health Services Research 2017; 52:1099-1117.
Koch-Gallenkamp L, Bertram H, Eberle A, Holleczek B, Schmid-Hopfner S, Waldmann A, Zeissig SR, Brenner H, Arndt V.
Fear of progression >=5 years after diagnosis of cancer. Results of the cancer registry and population-based CAESAR study.
Onkologe 2017; 23:295-299.
Papadimitriou N, Tsilidis KK, Orfanos P, Benetou V, Ntzani EE, Soerjomataram I, Künn-Nelen A, Pettersson-Kymmer U, Eriksson S, Brenner H, Schöttker B, Saum KU, Holleczek B, Grodstein FD, Feskanich D, Orsini N, Wolk A, Bellavia A, Wilsgaard T, Jorgensen L, Boffetta P, Trichopoulos D, Trichopoulou A.
Burden of hip fracture using disability-adjusted life-years: a pooled analysis of prospective cohorts in the CHANCES consortium.
Lancet Public Health 2017; 2:e239-246.
Guo Q, Burgess S, Turman C, Bolla MK, Wang Q,…, Arndt V,…, Brenner H,…, Hopper JL, Zheng W, Schmidt MK, Pharoah PDP.
Body mass index and breast cancer survival: A Mendelian randomisation analysis.
International Journal of Epidemiology 2017; 46:1814-1822.
Sud A, Thomsen H, Law PJ, Försti A, Inacio da Silva Filho M, Holroyd A, Broderick P, Orlando G, Lenive O, Wright L, Cooke R, Easton D, Pharoah P, Dunning A, Peto J, Canzian F, Eeles R, Kote-Jarai Z, Muir K, Pashayan N, The PRACTICAL consortium*, Hoffmann P, Nöthen MM, Jöckel KH, Pogge von Strandmann E, Lightfoot T, Kane E, Roman E, Lake A, Montgomery D, Jarrett RF, Swerdlow AJ, Engert A, Orr N, Hemminki K, Houlston RS.
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.
Nature Communications 2017; 8:1892.
*Collaborator from DKFZ: Brenner H
Matz M, Coleman MP, Sant M, Dolores Chirlaque M, Visser O, Gore M, Allemani C, the CONCORD Working Group*.
The histology of ovarian cancer: worldwide distribution and implications for international survival comparisons (CONCORD-2).
Gynecologic Oncology 2017; 144:405-413.
*Collaborator from DKFZ: Brenner H
NCD Risk Factor Collaboration (NCD-RisC).*
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults.
The Lancet 2017; 390:2627-2642.
*Collaborators on behalf of the ESTHER study: Brenner H, Saum KU
Jiao X, Aravidis C, Marikkannu R, Rantala J, Picelli S,…, Arndt V,…, Brenner H,…, Easton DF, Czene K, Hall P, Lindblom.
PHIP – a novel candidate breast cancer susceptibility locus on 6q14.1.
Oncotarget 2017; 8:102769-102782.
Gao X, Schöttker B.
Reduction-oxidation pathways involved in cancer development: a systematic review ofliterature reviews.
Oncotarget 2017; 8:51888-51906.
Bhardwaj M, Gies A, Werner S, Schrotz-King P, Brenner H.
Blood-based protein signatures for early detection of colorectal cancer: A systematic review.
Clinical and Translational Gastroenterology 2017; 8:e128.