Publikationen

Publikationen 2024

Publikationen 2023

Publikationen 2022

Publikationen 2021

Mukama T, Kharazmi E, Xu X, Sundquist K, Sundquist J, Brenner H, Fallah M.
Risk-adapted starting age of screening for relatives of patients with breast cancer.
JAMA Oncology 2020 6(1):68-74.

Fallah M, Mukama T, Kharazmi E.
Determining the Appropriate risk-adapted screening age for familial breast cancer—Reply.
JAMA Oncol 2020 (In Press; online publication date: 7 May 2020 DOI: 10.1001/jamaoncol.2020.0292).

Mukama T, Fallah M=, Xu X, Sundquist K, Sundquist J, Brenner H, Kharazmi E=.
Risk of invasive breast cancer in relatives of patients with breast carcinoma in situ.
BMC Medicine 2020 (In press)

Balavarca Y, Weigl K, Thomsen H, Brenner H.
Performance of individual and joint risk stratification by an environmental risk score and a genetic risk score in a colorectal cancer screening setting.
International Journal of Cancer 2020; 146:627-634.

McNabb S, Harrison TA, Albanes D, Berndt SI, Brenner H,…, Hoffmeister M,…, Wolk A, Woods MO, Phipps AI, Peters U.
Meta-analysis of 16 studies of the association of alcohol with colorectal cancer.
International Journal of Cancer 2020; 146:861-873.

Hilvo M, Meikle PJ, Pedersen ER, Tell GS, Dhar I, Brenner H, Schöttker B, Lääperi M, Kauhanen D, Koistinen KM, Jylhä A, Huynh K, Mellett NA, Tonkin AM, Sullivan DR, Simes J, Nestel P, Koenig W, Rothenbacher D, Nygard O, Laaksonen R.
Development and validation of ceramide and phospholipid based cardiovascular risk estimation score for coronary artery disease patients.
European Heart Journal 2020; 41:371-380.

Gào X, Wilsgaard T, Jansen EHJM, Yang X, Anusruti A, Brenner H, Schöttker B.
Serum total thiol levels and the risk of lung, colorectal, breast and prostate cancer: A prospective case-cohort study.
International Journal of Cancer 2020; 146:1261-1267.

Boakye D, Walter V, Jansen L, Martens U, Chang-Claude J, Hoffmeister M, Brenner H.
Magnitude of the age advancement effect of comorbidites in colorectal cancer prognosis.
Journal of the National Comprehensive Cancer Network 2020; 18:59-68.

Stocker H, Nabers A, Perna L, Möllers T, Rujescu D, Hartmann A, Holleczek B, Schöttker B, Gerwert K, Brenner H.
Prediction of Alzheimer’s disease diagnosis within 14 years through Aβ misfolding in blood plasma compared to APOE4 status, and other risk factors.
Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association 2020; 16:283-291.

Cornish AJ, Law PJ, Timofeeva M, Palin K, Farrington SM, Palles C, Jenkins MA, Casey G, Brenner H, Chang-Claude J, Hoffmeister M, Kirac I, Maughan T, Brezina S, Gsur A, Cheadle JP, Aaltonen LA, Tomlinson I, Dunlop MG, Houlston RS.
Modifiable pathways for colorectal cancer: a Mendelian randomisation analysis.
The Lancet Gastroenterology & Hepatology 2020; 5:55-62.

Niersmann C, Carstensen-Kirberg M, Maalmi H, Holleczek B, Roden M, Brenner H, Herder C, Schöttker B.
Higher circulating omentin is associated with increased risk of primary cardiovascular events in individuals with diabetes.
Diabetologia 2020; 63:410-418.

Guan Z, Raut JR, Weigl K, Schöttker B, Holleczek B, Zhang Y, Brenner H.
Individual and joint performance of DNA methylation profiles, genetic risk scores and environmental risk scores for predicting breast cancer risk.
Molecular Oncology 2020; 14:42-53.

Mukama T, Fallah M, Tian Y, Sundquist K, Sundquist J, Brenner H, Kharazmi E.
Risk-tailored starting age of breast cancer screening based on women’s reproductive profile: nationwide cohort study.
European Journal of Cancer 2020; 124:207-213.

Niedermaier T, Balavarca Y, Brenner H.
Stage specific sensitivity of fecal immunochemical tests for detecting colorectal cancer: systematic review and meta-analysis.
American Journal of Gastroenterology 2020; 115:56-69.

Möllers T, Perna L, Stocker H, Ihle P, Schubert I, Schöttker B, Frölich L, Bauer J, Brenner H.
Alzheimer’s disease medication and outcomes of hospitalization among patients with dementia.
Epidemiology and Psychiatric Sciences 2020; 29:e73, 1-9.

Bhardwaj M, Weigl K, Tikk K, Benner A, Schrotz-King P, Brenner H.
Multiplex screening of 275 plasma protein biomarkers for identifying a signature for early detection of colorectal cancer.
Molecular Oncology 2020; 14:8-21.

Gies A, Niedermaier T, Weigl K, Schrotz-King P, Hoffmeister M, Brenner H. Effect of long-term frozen storage and thawing of stool samples on faecal haemoglobin concentration and diagnostic performance of faecal immunochemical tests. Clinical Chemistry and Laboratory Medicine 2020; 58:390-398.

Schöttker B, Xuan Y, Gào X, Anusruti A, Brenner H.
Oxidatively damaged DNA/RNA and 8-isoprostane levels are associated with the development of type 2 diabetes mellitus at older age: results from a large cohort study.
Diabetes Care 2020; 43:130-136.

Bielska-Lasota M, Rossi S, Krzyzak M, Haelens A, Domenic A, De Angelis R, Maciejczyk A, Rodriguez-Barranco M, Zadnik V, Minicozzi P, EUROCARE-5 Working Group*.
Reasons for low cervical cancer survival in new accession European Union countries: a EUROCARE-5 study.
Archives of Gynecology and Obstetrics 2020; 301:591-602.
*Collaborator from DKFZ: Brenner H

Fachal L, Aschard H, Beesley J, Barnes DR, Allen J,..., Brenner H,..., Schöttker B,..., Simard J, Easton DF, Kraft P, Dunning AM.
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.
Nature Genetics 2020; 52:56-73.

Barahona Ponce C, Scherer D, Boekstegers F, Garate-Calderon V, Jenab M, Aleksandrova K, Katzke V, Weiderpass E, Bonet C, Moradi T, Fischer K, Bossers W, Brenner H, Schöttker B, Holleczek B, Hveem K, Eklund N, Völker U, Waldenberger M, Lorenzo Bermejo J.
Arsenic and gallbladder cancer risk: Mendelian randomization analysis of European prospective data.
International Journal of Cancer 2020; 146:2648-2650.

Guo F, Chen C, Schöttker B, Holleczek B, Hoffmeister M, Brenner H.
Changes in colorectal cancer screening use after introduction of alternative screening offer in Germany: Prospective cohort study.
International Journal of Cancer 2020; 146:2423-2432.

Anusruti A, Xuan Y, Gào X, Jansen E, Laetsch DC, Brenner H, Schöttker B.
Factors associated with high oxidative stress in type 2 diabetes patients: a meta-analysis of two cohort studies.
BMJ Open Diabetes Research & Care 2020; 8:e000933.

Anusruti A, Jansen EHJM, Gào X, Xuan Y, Brenner H, Schöttker B.
Longitudinal associations of body mass index, waist circumference and waist to hip ratio with biomarkers of oxidative stress in older adults: Results of a large cohort study.
Obesity Facts 2020; 13:66-76.

Boekstegers F, Marcelain K, Barahona Ponce C, Baez Benavides PF, Müller B, de Toro G, Retamales J, Barajas O, Ahumada M, Morales E, Rojas A, Sanhueza V, Loader D, Rivera MT, Gutiérrez L, Bernal G, Ortega A, Montalvo D, Portino S, Bertrán ME, Gabler F, Spencer L, Olloquequi J, Silos RG, Fischer C, Scherer D, Jenab M, Aleksandrova K, Katzke V, Weiderpass E, Moradi T, Fischer K, Bossers W, Brenner H, Hveem K, Eklund N, Völker U, Waldenberger M, Guajardo MF, Gonzalez-Jose R, Bedoya G, Bortolini MC, Canizales S, Gallo C, Linares AR, Rothhammer F, Bermejo JL.
ABCB1/4 Gallbladder cancer risk variants identified in India also show strong effects in Chileans.
Cancer Epidemiology 2020; 65:101643.

Alwers E, Jansen L, Bläker H, Kloor M, Tagscherer K, Roth W, Boakye D, Herpel E, Grüllich C, Chang-Claude J, Brenner H, Hoffmeister M.
Microsatellite instability and survival after adjuvant chemotherapy among stage II and III colon cancer patients: Results from a population-based study.
Molecular Oncology 2020; 14:363-372.

Carr PR, Amitay E, Jansen L, Alwers E, Roth W, Herpel E, Kloor M, Schneider M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.
Association of body mass index and major molecular pathological markers of colorectal cancer among men and women.
American Journal of Clinical Nutrition 2020; 111:562-569.

Beyerle J, Holowatyj AN, Haffa M, Frei E, Gigic B, Schrotz-King P, Böhm J, Habermann N, Stiborova M, Scherer D, Koelsch T, Skender S, Becker N, Herpel E, Schneider M, Ulrich A, Schirmacher P, Chang-Claude J, Brenner H, Hoffmeister M, Haug U, Owen RW, Ulrich CM.
Expression patterns of xenobiotic metabolizing enzymes in tumor and adjacent normal mucosa tissues among patients with colorectal cancer: The ColoCare study.
Cancer Epidemiology, Biomarkers & Prevention 2020; 29:460-469.

Jaeschke L, Steinbrecher A, Boeing H, Gastell S, Ahrens W,..., Brenner H,..., Schipf S, Schmidt B, Zinkhan M, Pischon T.
Factors associated with habitual time spent in different physical activity intensities using multiday accelerometry.
Scientific Reports 2020; 10:774.

Riegger J, Rehm M, Büchele G, Brenner H, Günther KP, Rothenbacher D, Brenner RE.
Serum cartilage oligomeric matrix protein in late-stage osteoarthritis: Association with clinical features, renal function and cardiovascular biomarkers.
Journal of Clinical Medicine 2020; 9:268.

Papadimitriou N, Dimou N, Tsilidis K, Banbury B, Martin R,..., Brenner H,..., Hoffmeister M,..., Wu A, Peters U, Gunter M, Murphy N.
Physical activity and risks of breast and colorectal cancer: a Mendelian randomization analysis.
Nature Communications 2020; 11:597.

Escala-Garcia M, Abraham J, Andrulis IL, Anton-Culver H, Arndt V,..., Brenner H,..., Dörk T, Easton D, Canisius S, Schmidt M.
A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.
Nature Communications 2020; 11:312.

Bhardwaj M, Weigl K, Tikk K, Holland-Letz T, Schrotz-King P, Borchers CH, Brenner H.
Multiplex quantitation of 270 plasma protein markers to identify a signature for early detection of colorectal cancer.
European Journal of Cancer 2020; 127:30-40.

Boehlen FH, Herzog W, Schellberg D, Maatouk I, Schöttker B, Brenner H, Wild B.
Gender-specific predictors of generalized anxiety disorder symptoms in older adults: results of a large population-based study.
Journal of Affective Disorders 2020; 262:174-181.

Schipf S, Schöne G, Schmidt B, Günther K, Stübs G,..., Brenner H,..., Holleczek B,..., Wirkner K, Völzke H, Pischon T, Ahrens W.
Die Basiserhebung der NAKO Gesundheitsstudie: Teilnahme an den Untersuchungsmodulen, Qualitätssicherung und Nutzung von Sekundärdaten.
Bundesgesundheitsblatt 2020; 63:254-266.

Dragano N, Reuter M, Greiser KH, Becher H, Zeeb H,..., Holleczek B, Brenner H,..., Legath N, Ahrens W, Lampert T, Schmidt B.
Soziodemografische und erwerbsbezogene Merkmale in der NAKO Gesundheitsstudie.
Bundesgesungsheitsblatt 2020; 63:267-278.

Leitzmann M, Gastell S, Hillreiner A, Herbolsheimer F, Baumeister SE,..., Brenner H,..., Holleczek B,..., Thierry S, Völzke H, Wirkner K, Steindorf K.
Körperliche Aktivität in der NAKO Gesundheitsstudie: erste Ergebnisse des multimodalen Erhebungskonzepts.
Bundesgesundheitsblatt 2020; 63:301-311.

Karrasch S, Peters A, Meisinger C, Ferland M, Jaeschke L,..., Leitzmann M, Brenner H, Holleczek B, Schulz H.
Lungenfunktion in der NAKO Gesundheitsstudie: Methoden und erste Ergebnisse.
Bundesgesundheitsblatt 2020; 63:322-331.

Wolf K, Kraus U, Dzolan M, Bolte G, Lakes T,..., Brenner H,..., Holleczek B,..., Wirkner K, Zschocke J, Peters A, Schneider A.
Nächtliche Vekehrslärmbelästigung in Deutschland: individuelle und regionale Unterschiede in der NAKO Gesundheitsstudie.
Bundesgesundheitsblatt 2020; 63:332-343.

Gruner LF, Hoffmeister M, Ludwig L, Brenner H.
Effect of various invitation schemes on use of fecal immunochemical tests (FITs) for colorectal cancer screening: Protocol for a randomized controlled
trial.
JMIR Research Protocols 2020; 9:e16413.

Trares K*, Gào X*, Perna L, Rujescu D, Stocker H, Möllers T, Beyreuther K, Brenner H, Schöttker B.
Associations of urinary 8-iso-prostaglandin F2α levels with all-cause dementia, Alzheimer's disease and vascular dementia incidence: results from a prospective cohort study.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2020; 16:804-813.
*geteilte Erstautorenschaft

Gigic B, Nattenmüller J, Schneider M, Kulu Y, Syrjala K, Böhm J, Schrotz-King P, Brenner H, Colditz GA, Figueiredo JC, Grady WM, Li CI, Shibata D, Siegel EM, Toriola AT, Kauczor HU, Ulrich A, Ulrich C.
The role of CT-quantified body composition on longitudinal health-related quality of life in colorectal cancer patients: the ColoCare study.
Nutrients 2020; 12:1247.

Mukama T, Kharazmi E, Sundquist K, Sundquist J, Brenner H, Fallah M.
Familial risk of breast cancer by dynamic, accumulative, and static definition of family history.
Cancer 2020; 126:2837-2848.

Amitay E, Carr P, Jansen L, Roth W, Alwers E, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.
Smoking, alcohol consumption and colorectal cancer risk by molecular pathological subtypes and pathways.
British Journal of Cancer 2020; 122:1604-1610.

Jansen L, Schröder CC, Emrich K, Holleczek B, Pritzkuleit R, Brenner H.
Disclosing progress in cancer survival with less delay.
International Journal of Cancer 2020; 147:838-846.

Feng H, Gusev A, Pasaniuc B, Wu L, Long J,..., Brenner H,..., Chenevix-Trench G, Zheng W, Kraft P, Jiang X.
Transcriptome-wide association study of breast cancer risk by estrogen-receptor status.
Genetic Epidemiology 2020; 44:442-468.

Liu J, Prager-van der Smissen WJC, Collée M, Bolla MK, Wang Q,..., Arndt V,..., Brenner H,..., Easton DF, Hooning MJ, Martens JWM, Hollestelle A.
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
Scientific Reports 2020; 10:9688.

Yang Y, Wu L, Shu XO, Cai Q, Shu X, Li B, Guo X, Ye F, Michailidou K, Bolla MK, Wang Q, Dennis J, Andrulis IL, Brenner H, Chenevix-Trench G, Campa D, Castelao JE, Gago-Dominguez M, Dörk T, Hollestelle A, Lophatananon A, Muir K, Neuhausen SL, Olsson H, Sandler DP, Simard J, Kraft P, Pharoah PDP, Easton DF, Zheng W, Long J.
Genetically predicted levels of DNA methylation biomarkers and breast cancer risk: data from 228,951 women of European descent.
Journal of the National Cancer Institute 2020; 112:295-304.

NCD Risk Factor Collaboration (NCD-RisC).*
National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: an analysis of trends in Asian and Western countries.
International Journal of Epidemiology 2020; 49:173-192.
*Collaborators on behalf of the ESTHER study: Brenner H, Saum KU, Schöttker B

Holleczek B, SchöttkerB, Brenner H.
Helicobacter pylori infection, chronic atrophic gastritis and risk of stomach and esophagus cancer: results from the prospective population-based ESTHER cohort study.
International Journal of Cancer 2020; 146:2773-2783.

Geijsen AJMR, van Roekel EH, van Duijnhoven FJB, Achaintre D, Bachleitner-Hofmann T,..., Brenner H,..., Hoffmeister M,..., Schrotz-King P,..., Ulrich AB, Ulrich CM, Weijenberg MP, Kok DE.
Plasma metabolites associated with colorectal cancer stage: findings from an international consortium.
International Journal of Cancer 2020; 146:3256-3266.

Kapoor PM, Lindström S, Behrens S, Wang X, Michailidou K, Bolla MK, Wang Q, Dennis J, Dunning AM, Pharoah PDP, Schmidt MK, Kraft P, Garcia-Closas M, Easton DF, Milne RL, Chang-Claude J, on behalf of the Breast Cancer Association Consortium.*
Assessment of interactions between 205 breast cancer susceptibility loci and 13 established risk factors in relation to breast cancer risk in the Breast Cancer Association Consortium.
International Journal of Epidemiology 2020; 49:216-230.
*Co-authors on behalf of ESTHER study: Arndt V, Brenner H, Schöttker B

Adam S, Doege D, Koch-Gallenkamp L, Thong MSY, Bertram H, Eberle A, Holleczek B, Pritzkuleit R, Waldeyer-Sauerland M, Waldmann A, Zeissig SR, Jansen L, Rohrmann S, Brenner H, Arndt V.
Age-specific health-related quality of life in disease-free long-term prostate cancer survivors versus male
population controls – results from a population-based study.
Supportive Care in Cancer 2020; 28:2875-2885.

Khankari NK, Banbury BL, Borges MC, Haycock PC, Albanes D, Arndt V,..., Brenner H,..., Hoffmeister M,..., Murff HJ, Gruber SB, Peters U, Zheng W.
Mendelian randomization of circulating polyunsaturated fatty acids and colorectal cancer risk.
Cancer Epidemiology, Biomarkers and Prevention 2020; 29:860-870.

Pulte D, Jansen L, Brenner H.
Changes in long term survival after diagnosis with common hematologic malignancies in the early 21st century.
Blood Cancer Journal 2020; 10:56.

Gruner LF, Hoffmeister M, Ludwig L, Brenner H.
Effect of various invitation schemes on use of fecal immunochemical tests (FITs) for colorectal cancer screening: Protocol for a randomized controlled trial.
JMIR Research Protocols 2020; 9:e16413.

d'Errico M, Alwers E, Zhang Y, Edelmann D, Brenner H, Hoffmeister M.
Identification of prognostic DNA methylation biomarkers in patients with gastrointestinal adenocarcinomas: a systematic review of epigenome-wide studies.
Cancer Treatment Reviews 2020; 82:101933.

Vishram-Nielsen JKK, Laurent S, Nilsson PM, Linneberg A, Sehested TSG, Greve SV, Pareek M, Palmieri
L, Giampaoli S, Donfrancesco C, Kee F, Mancia G, Cesana G, Veronesi G, Kuulasmaa K, Salomaa V, Kontto J, Palosaari T, Sans S, Ferrieres J, Dallongeville J, Söderberg S, Moitry M, Drygas W, Tamosiunas A, Peters A, Brenner H, Njolstad I, Olsen MH, on behalf of the MORGAM project.
Does estimated pulse wave velocity add prognostic information? The MORGAM prospective cohort project.
Hypertension 2020; 75:1420-1428.

Ochoa-Rosales C, Portilla-Fernandez E, Nano J, Wilson R, Lehne B, Mishra PP, Gao X, Ghanbari M,
Rueda-Ochoa OL, Juvinao-Quintero D, Loh M, Zhang W, Kooner JS, Grabe HJ, Felix SB, Schöttker B, Zhang Y, Gieger C, Müller-Nurasyid M, Heier M, Peters A, Lehtimäki T, Teumer A, Brenner H,
Waldenberger M, Ikram MA, van Meurs JBJ, Franco OH, Voortman T, Chambers J, Stricker BH, Muka T.
Epigenetic link between statin therapy and type 2 diabetes.
Diabetes Care 2020; 43:875-884.

Murphy N, Carreras-Torres R, Song M, Chan AT, Martin RM,..., Brenner H,..., Hoffmeister M,..., Wu AH, Zheng W, Peters U, Gunter MJ.
Circulating levels of insulin-like growth factor 1 and insulin-linke growth factor binding protein 3 associate with risk of colorectal cancer based on serologic and Mendelian randomization analyses.
Gastroenterology 2020; 158:1300-1312.

Amitay EL, Carr PR, Jansen L, Alwers E, Roth W, Herpel E, Kloor M, Bläker H, Chang- Claude J, Brenner H, Hoffmeister M.
Postmenopausal hormone replacement therapy and colorectal cancer risk by molecular subtypes and pathways.
International Journal of Cancer 2020; 147:1018-1026.

Archambault AN, Su YR, Jeon J, Thomas M, Lin Y,..., Brenner H,..., Hoffmeister M,..., Corley DA, Hsu L, Peters U, Hayes RB.
Cumulative burden of colorectal cancer-associated genetic variants is more strongly associated with
early-onset vs late-onset cancer.
Gastroenterology 2020; 158:1274-1286.

Niedermaier T, Amitay E, Gies A, Weigl K, Hoffmeister M, Brenner H.
Impact of inadequate bowel cleansing on colonoscopic findings in routine screening practice.
Clinical and Translational Gastroenterology 2020; 11:e00169.

Trares K*, Gào X*, Perna L, Rujescu D, Stocker H, Möllers T, Beyreuther K, Brenner H, Schöttker B.
Associations of urinary 8-iso-prostaglandin F2α levels with all-cause dementia, Alzheimer's disease and vascular dementia incidence: results from a prospective cohort study.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2020; 16:804-813.
*geteilte Erstautorenschaft

Neumeyer S, Butterbach K, Banbury BL, Berndt SI, Campbell PT, Chlebowski R, Chan AT, Giovannucci EL, Joshi AD, Ogino S, Song M, McCullough M, Manson JE, Sakoda LC, Schoen RE, Slattery ML, White
E, Maalmi H, Win AK, Figueiredo JC, Hopper J, Macrae F, Peters U, Brenner H, Hoffmeister M, Newcomb PA, Chang-Claude J.
Genetic predictors of circulating 25-hydroxyvitamin D and prognosis after colorectal cancer.
Cancer Epidemiology, Biomarkers & Prevention 2020; 29:1128-1134.

Möllers T, Perna L, Stocker H, Ihle P, Schubert I, Schöttker B, Frölich L, Brenner H.
New use of psychotropic medication after hospitalization among people with dementia.
International Journal of Geriatric Psychiatry 2020; 35:640-649.

Phipps AI*, Alwers E*, Harrison T*, Banbury B, Brenner H, Campbell PT, Chang-Claude J, Buchanan D, Chan AT, Farris AB, Figueiredo J, Gallinger S, Giles G, Hudson T, Newcomb PA, Slattery ML, Song M, Ogino S, Zaidi SH, Hoffmeister M†, Peters U†.
Association between molecular subtypes of colorectal tumors and patient survival, based on pooled analysis of 7 international studies.
Gastroenterology 2020; 158:2158-2168.
*geteilte Erstautorenschaft
† geteilte Letztautorenschaft

Ji X, Mukherjee S, Landi M, Bossé Y, Joubert P,..., Brenner H, Chanock S, Brennan P, McKay J, Amos C. Protein-altering germline mutations implicate novel genes related to lung cancer development.
Nature Communications 2020; 11:2220.

Eyl RE, Thong MSY, Carr PR, Jansen L, Koch-Gallenkamp L, Hoffmeister M, Chang- Claude J, Brenner H, Arndt V.
Physical activity and long-term fatigue among colorectal cancer survivors – a population- based prospective study.
BMC Cancer 2020; 20:438.

Gigic B, Nattenmüller J, Schneider M, Kulu Y, Syrjala K, Böhm J, Schrotz-King P, Brenner H, Colditz GA, Figueiredo JC, Grady WM, Li CI, Shibata D, Siegel EM, Toriola AT, Kauczor HU, Ulrich A, Ulrich C.
The role of CT-quantified body composition on longitudinal health-related quality of life in colorectal cancer patients: the ColoCare study.
Nutrients 2020; 12:1247.

NCD Risk Factor Collaboration (NCD-RisC).*
Repositioning of the global epicenter of non-optimal cholesterol.
Nature 2020; 582:73-77.
*Collaborators on behalf of the ESTHER study: Brenner H, Saum KU, Schöttker B

Cardoso R, Guo F, Heißer T, Hoffmeister M, Brenner H.
Utilisation of colorectal cancer screening tests in European countries by type of screening offer: Results from the European Health Interview Survey.
Cancers 2020; 12:E1409.

Yu H, Raut JR, Schöttker B, Holleczek B, Zhang Y, Brenner H.
Individual and joint contributions of genetic and methylation risk scores for enhancing lung cancer risk stratification: data from a population-based cohort in Germany.
Clinical Epigenetics 2020; 12:89.

Peng L, Balavarca Y, Niedermaier T, Weigl K, Hoffmeister M, Brenner H.
Risk-adapted cutoffs in colorectal cancer screening by fecal immunochemical tests.
American Journal of Gastroenterology 2020; 115:1110-1116.

Scherer D, Deutelmoser H, Balavarca Y, Toth R, Habermann N, Buck K, Kap EJ, Botma A, Seibold P, Jansen L, Bermejo JL, Weigl K, Benner A, Hoffmeister M, Ulrich A, Brenner H, Burwinkel B, Chang-Claude J, Ulrich CM.
Polymorphisms in the angiogenesis-related genes EFNB2, MMP2 and JAG1 are associated with survival of colorectal cancer patients.
International Journal of Molecular Sciences 2020; 21:5395.

Guo F, de Brabander I, Francart J, Candeur M, Polus M, Van Eycken L, Brenner H.
Benefits of switching from guaiac-based faecal occult blood to faecal immunochemical testing: Experience from the Wallonia-Brussels colorectal cancer screening programme.
British Journal of Cancer 2020; 122:1109-1117.

Sirri E, Kieschke J, Vohmann C, Katalinic A, Nennecke A, Ressing M, Eberle A, Holleczek B, Jansen L, Brenner H, for the GEKID Cancer Survival Working Group.
Survival of malignant mesothelioma and other rare thoracic cancers in Germany and the United States.
Internal Journal of Cancer 2020; 147:1548-1558.

Finke I, Behrens G, Schwettmann L, Gerken M, Pritzkuleit R, Holleczek B, Brenner H, Jansen L, for the German Cancer Survival Working Group.
Socioeconomic differences and lung cancer survival in Germany: Investigation based on population-based clinical cancer registration.
Lung Cancer 2020; 142:1-8.

Carr P, Weigl K, Edelmann D, Jansen L, Chang J, Brenner H, Hoffmeister M.
Estimation of absolute risk of colorectal cancer based on healthy lifestyle, genetic risk, and colonoscopy status in a population-based study.
Gastroenterology 2020; 159:129-138.e9.

Campa D, Gentiluomo M, Obazee O, Ballerini A, Vodickova L,..., Brenner H,..., Schöttker B,..., Kaaks R, Neoptolemos J, Lucchesi M, Canzian F.
Genome-wide association study identifies an early onset pancreatic cancer risk locus.
International Journal of Cancer 2020; 147:2065-2074.

Peter RS, Meyer ML, Mons U, Schöttker B, Keller F, Schmucker R, Koenig W, Brenner H, Rothenbacher D.
Long-term trajectories of anxiety and depression in patients with stable coronary heart diesase and risk of subsequent cardiovascular events.
Depression and Anxiety 2020; 37:784-792.

Ali Khan U, Fallah M, Tian Y, Sundquist K, Sundquist J, Brenner H, Kharazmi E.
Personal history of diabetes as important as family history of colorectal cancer for risk of colorectal cancer: A nationalwide cohort study.
American Journal of Gastroenterology 2020; 115:1103-1109.

Eyl RE, Koch-Gallenkamp L, Jansen L, Walter V, Carr PR, Hoffmeister M, Chang-Claude J, Brenner H, Arndt V.
Physical activity and long-term quality of life among colorectal cancer survivors – a population-based prospective study.
Cancer Prevention Research 2020; 13:611-622.

Tian Y, Kharazmi E, Brenner H, Xu X, Sundquist K, Sundquist J, Fallah M.
Calculating starting age for screening in relatives of patients with colorectal cancer based on data from large nationwide datasets.
Gastroenterology 2020; 159:159-168.e3.

Gredner T, Niedermaier T, Brenner H, Mons U.
Impact of tobacco control policies on smoking-related cancer incidence in Germany 2020 to 2050 – a simulation study.
Cancer Epidemiology, Biomarkers & Prevention 2020; 29:1413-1422.

Ma J, Rebholz CM, Braun KVE, Reynolds LM, Aslibekyan S,..., Zhang Y, Schöttker B, Brenner H,..., Hu FB, Fornage M, Voortman T, Levy D.
Whole blood DNA methylation signatures of diet are associated with cardiovascular disease risk factors and all-cause mortality.
Circulation: Genomic and Precision Medicine 2020; 13:e002766.

Zaidi SH, Harrison TA, Phipps AI, Steinfelder R, Trinh QM,..., Alwers E, Amitay EL,..., Brenner H,..., Hoffmeister M,..., Thibodeau SN, Sun W, Hudson TJ, Peters U.
Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.
Nature Communications 2020; 11:3644.

Wu L, Yang Y, Guo X, Shu XO, Cai Q, Shu X, Li B, Tao R, Wu C, Nikas JB, Sun Y, Zhu J, Roobol MJ, Giles GG, Brenner H, John EM, Clements J, Grindedal EM, Park JY, Stanford JL, Kote-Jarai Z, Haiman CA, Eeles RA, Zheng W, Long J, PRACTICAL, CRUK, BPC3, CAPS, PEGASUS consortia.
An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk.
Nature Communications 2020; 11:3905.

Heißer T, Weigl K, Hoffmeister M, Brenner H.
Age-specific sequence of colorectal cancer screening options in Germany: a model-based critical evaluation.
PLOS Medicine 2020; 17:e1003194.

Brenner H, Holleczek B, Schöttker B.
Vitamin D insufficiency and deficiency and mortality from respiratory diseases in a cohort of older adults: potential for limiting the death toll during and beyond the COVID-19 pandemic?
Nutrients 2020; 12:E2488.

Huang L, Jansen L, Balavarca Y, van der Geest L, Lemmens V, Groot Koerkamp B, van Santvoort HC, Grützmann R, Besselink MG, Schrotz-King P, Brenner H.
Significance of exmined lymp node number in accurate staging and long-term survival in resected stage I-II pancreatic cancer-more is better? A large international population-based cohort study.
Annals of Surgery (im Druck).

Laetsch DC, Hoppe LK, Saum KU, Haefeli WE, Brenner H, Schöttker B.
Investigation of a possible association of potentially inappropriate medication for older adults and frailty in a prospective cohort study from Germany.
Age and Ageing (im Druck).

Weigl K, Tikk K, Hoffmeister M, Hampe J, Igel S, Kolligs F, Klug SJ, Mansmann U, Müller O, Nagel JM, Pichler M, Schwab M, Schweigler D, Stephan AM, De Toni EN, Brenner H.
Prevalence of a first-degree relative with colorectal cancer and uptake of screening among persons 40 to 54 years old.
Clinical Gastroenterology and Hepatology (im Druck).

Niedermaier T, Tikk K, Gies A, Bieck S, Brenner H.
Sensitivity of fecal immunochemical test for colorectal cancer detection differs strongly according to stage and location.
Clinical Gastroenterology and Hepatology (im Druck).

Kar SP, Brenner H, Giles GG, Huo D, Milne RL, Rennert G, Simard J, Zheng W, Burgess S, Pharoah PDP.
Body mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk.
International Journal of Epidemiology (im Druck).

Campbell PT, Lin Y, Bien SA, Figueiredo JC, Harrison TA, Guinter MJ, Berndt SI, Brenner H, Chan AT, Chang-Claude J, Gallinger SJ, Gapstur SM, Giles GG, Giovannucci E, Gruber SB, Gunter M, Hoffmeister M, Jacobs EJ, Jenkins MA, Le Marchand L, Li L, McLaughlin JR, Murphy N, Milne RL, Newcomb PA, Newton C, Ogino S, Potter JD, Rennert G, Rennert HS, Robinson J, Sakoda LC, Slattery ML, Song Y, White E, Woods MO, Casey G, Hsu L, Peters U.
Association of body mass index with colorectal cancer risk according to genome-wide variants.
Journal of the National Cancer Institute (im Druck).

Chen H, Lu M, Liu C, Zou S, Du L, Liao X, Dong D, Wei D, Gao Y, Zhu C, Zhu L, Zheng W, Xiao H, Kong Y, Yin H, Zhou H, Ying R, Wang B, Zhang J, Zhang X, Zhang Q, Zhang X, Zhang Y, Wang H, Guo L, Liu L, Ren J, Shi J, Miao X, Brenner H, Dai M.
Comparative evaluation of participation and diagnostic yield of colonoscopy vs fecal immunochemical test vs risk-adapted screening in colorectal cancer screening: interim analysis of a multicenter randomized controlled trial (TARGET-C).
American Journal of Gastroenterology (im Druck).

Boakye D, Jansen L, Schöttker B, Jansen E, Schneideer M, Halama N, Gào X, Chang-Claude J, Hoffmeister M, Brenner H.
Blood markers of oxidative stress are strongly associated with poorer prognosis in colorectal cancer patients.
International Journal of Cancer (im Druck).

Jansen L*, Merz M*, Engelhardt M, Weisel K, Scheid C, Straka C, Langer C, Salwender H, Einsele H, Kröger N, Beelen D, Dreger P, Goldschmidt H*, Brenner H*, German National Registry for Stem Cell Transplants (DRST).
Autologous stem cell transplantation in multiple myeloma patients: Utilization patterns and hospital effects.
Leukemia and Lymphoma (im Druck).
*geteilte Erstautorenschaft

Jansen L, Behrens G, Finke I, Maier W, Gerken M, Pritzkuleit R, Holleczek B, Brenner H.
Area-based socioeconomic inequalities in colorectal cancer survival in Germany: Investigation based on population-based clinical cancer registration.
Frontiers in Oncology (im Druck).

Guo F, Weigl K, Carr PR, Heißer T, Jansen L, Knebel P, Chang-Claude J, Hoffmeister M, Brenner H.
Use of polygenic risk scores to select screening intervals after negative findings from colonoscopy.
Clinical Gastroenterology and Hepatology (im Druck).

Stocker H, Perna L, Weigl K, Möllers T, Schöttker B, Thomsen H, Holleczek B, Rujescu D, Brenner H.
Prediction of clinical diagnosis of Alzheimer's disease, vascular, mixed, and all-cause dementia by a polygenic riskscore and APOE status in a community-based prospectively followed over 17 years.
Molecular Psychiatry (im Druck).

Kather JN, Heij LR, Grabsch HI, Loeffler C, Echle A, Muti HS, Krause J, Niehues JM, Sommer KAJ, Bankhead P, Kooreman LFS, Schulte JJ, Cipriani NA, Buelow RD, Boor P, Ortiz-Brüchle N, Hanby AM, Speirs V, Kochanny S, Patnaik A, Srisuwananukorn A, Brenner H, Hoffmeister M, van den Brandt PA, Jäger D, Trautwein C, Pearson AT, Luedde T.
Pan-cancer image-based detection of clinically actionable genetic alterations.
Nature Cancer (im Druck).

Gruner LF, Ludwig L, Hoffmeister M, Meny S, Brenner H.
The effects of different invitation schemes on use of fecal immunochemical tests (FITs): Results from a randomized controlled trial.
Effekte verschiedener Einladungsmodelle auf die Inanspruchnahme immunologischer Tests auf Blut im Stuhl: Ergebnisse einer randomisierten kontrollierten Studie.
Deutsches Ärzteblatt (im Druck).

Kapoor PM, Mavaddat N, Choudhury PP, Wilcox AN, Lindström S,..., Arndt V,..., Brenner H,..., Holleczek B,..., Schöttker B,..., Easton DF, Milne RL, Garcia-Closas M, Chang-Claude J.
Combined associations of a polygenic risk score and classical risk factors with breast cancer risk.
Journal of the National Cancer Institute (im Druck).

Chen LJ, Trares K, Laetsch DC, Nguyen Thi Ngoc M, Brenner H, Schöttker B.
Systematic review and meta-analysis on the associations of polypharmacy and potentially inappropriate medication with adverse outcomes in older cancer patients.
Journal of Gerontology: Medical Sciences (im Druck).

Zhang Y, Bewerbunge-Hudler M, Schick M, Burwinkel B, Herpel E, Hoffmeister M, Brenner H.
Blood-derived DNA methylation predictors of mortality discriminate tumor and healthy tissue in multiple organs.
Molecular Oncology (im Druck).

Huynh-Le MP, Chieh Fan C, Karunamuni R, Walsh EI, Turner EL,..., Brenner H, Schöttker B, Holleczek B,..., Mills IG, Andreassen OA, Dale AM, Seibert TM.
A genetic risk score to personalize prostate cancer screening, applied to population data.
Cancer Epidemiology, Biomarkers & Prevention (im Druck).

Schrotz-King P, Hoffmeister M, Sauer P, Schaible A, Brenner H.
Protocol of the DARIO randomized trial: Effects of alternative offers of screening sigmoidoscopy and colonoscopy on utilization and yield of endoscopic screening for colorectal neoplasms.
JMIR Research (im Druck).

Echle A, Grabsch HI, Quirke P, van den Brandt PA, West NP, Hutchins GGA, Heij LR, Tan X, Richman SD, Krause J, Alwers E, Jenniskens J, Offermans K, Gray R, Brenner H, Chang-Claude J, Trautwein C, Pearson AT, Boor P, Luedde T, Gaisa NT, Hoffmeister M, Kather JN.
Clinical-grade detection of microsatellite instability in colorectal tumors by deep learning.
Gastroenterology (im Druck).

Bravi F, Lee YCA, Hashibe M, Boffetta P, Conway DI, Ferraroni M, La Vecchia C, Edefonti V, on behalf of the INHANCE Consortium investigators.*
Lessons learned from the INHANCE consortium: an overview of recent results on head and neck cancer.
Oral Diseases (im Druck).
*Collaborators from DKFZ: Brenner H

Karunamuni R, Huynh-Le MP, Fan C, Eeles R, Easton D,..., Brenner H, Schöttker B, Holleczek B,..., Andreassen O, Dale AM, Seibert T, and the Practical Consortium.
The effect of sample size on polygenic hazard models for prostate cancer.
Nature (im Druck).

Hoffmeister M, Bläker H, Jansen L, Alwers E, Amitay EL, Carr PR, Kloor M, Herpel E, Roth W, Chang-Claude J, Brenner H.
Colonoscopy and reduction of colorectal cancer risk by molecular tumor subtypes: a population-based case-control study.
American Journal of Gastroenterology (im Druck).

Xu X, Kharazmi E, Tian Y, Sundquist K, Sundquist J, Brenner H, Fallah M.
Risk of invasive prostate cancer and prostate cancer death in relatives of patients with prostatic borderline or in situ neoplasia: A nationwide cohort study.
Cancer (im Druck). 

Nguyen TNM, Laetsch DC, Chen LJ, Haefeli WE, Meid AD, Brenner H, Schöttker B.
Pain severity and analgesics use in the community-dwelling older population. A drug utilization study from Germany.
European Journal of Clinical Pharmacology (im Druck).

Thomas M, Sakoda LC, Hoffmeister M, Lee JK, van Duijnhoven FJB,..., Arndt V,..., Brenner H, Corley DA, Peters U, Hsu L.
Genome-wide modelling of polygenic risk score in colorectal cancer risk.
The American Journal of Human Genetics (im Druck).

Ahadova A, Seppälä T, Engel C, Gallon R, Burn J, Holinski-Feder E, Steinke-Lange V, Möslein G, Nielsen M, ten Broeke S, Laghi L, Dominguez-Valentin M, Capella G, Macrae F, Hüneburg R, Nattermann J, Hoffmeister M, Brenner H, Bläker H, von Knebel Doeberitz M, Sampson JR, Vasen H, Mecklin JP, Moller P, Kloor M.
The "unnatural" history of colorectal cancer in Lynch syndrome: lessons from colonoscopy surveillance.
International Journal of Cancer (im Druck).

Raut J, Guan Z, Schrotz-King P, Brenner H.
Fecal DNA methylation markers for detecting stages of colorectal cancer and its precursors: a systematic review.
Clinical Epigenetics (im Druck).

Jarvik GP, Wang X, Fontanillas P, Kim E, Chanprasert S,..., Brenner H,..., Hoffmeister M,..., Jenkins MA, Mountain J, Peters U, Crosslin DR.
Hemochromatosis risk genotype is not associated with colorectal cancer or age at its diagnosis.
Human Genetics and Genomics Advances (im Druck).

Chen C, Stock C, Hoffmeister M, Brenner H.
Self-reported lower gastrointestinal endoscopy use and changes in colorectal cancer mortality rates in European countries.
Clinical and Translational Gastroenterology (im Druck).

Repky S, Büchele G, Günther KP, Huch K, Brenner H, Stürmer T, Beyersmann J, Brenner RE, Rothenbacher D.
Five years' trajectories of functionality and pain in patients after hip or knee replacement and association with long-term patient survival.
Scientific Reports (im Druck).

Jansen L, Boakye D, Alwers E, Carr PR, Reissfelder C, Schneider M, Martens UM, Chang-Claude J, Hoffmeister M, Brenner H.
Uptake rates of novel therapies and survival among privately compared to publicly insured colorectal cancer patients in Germany.
Journal of the National Comprehensive Cancer Network (im Druck).

Bläker H, Haupt S, Morak M, Holinski-Feder E, Arnold A,..., Alwers E,..., Brenner H,..., von Knebel Doeberitz M, Ahadova A, Hoffmeister M, Kloor M.
Age-dependent performance of BRAF mutations testing in Lynch syndrome diagnostics.
International Journal of Cancer (im Druck).

Barahona Ponce C, Scherer D, Brinster R, Boekstegers F, Marcelain K,..., Brenner H,..., Gallo C, Ruiz Linares A, Rothhammer F, Lorenzo Bermejo J.
Gallstones, body mass index, C-reactive protein and gallbladder cancer – Mendelian randomization analysis of Chilean and European genotype data.
Hepatology (im Druck).

Heisser T, Guo F, Niedermaier T, Holleczek B, Hoffmeister M, Brenner H.
Low risk of advanced neoplasms for up to 20 years after negative colonoscopy: potential for personalized follow-up screening intervals.
Gastroenterology (im Druck).

Deutelmoser H, Scherer D, Brenner H, Waldenberger M, Suhre K, Kastenmüller G, Bermejo L.
Robust Huber-Lasso for improved prediction of protein metabolite, and gene expression levels relying on individual genotype data.
Briefings in Bioinformatics (im Druck).

Jansen L, Holleczek B, Kraywinkel K, Weberpals J, Schröder CC, Eberle A, Emrich K, Kajüter H, Katalinic A, Kieschke J, Nennecke A, Sirri E, Heil J, Schneeweiss A, Brenner H.
Divergent patterns and trends in breast cancer incidence, mortality and survival among older women in Germany and the United States.
Cancers (im Druck).

Brenner DR, Fehringer G, Zhang ZF, Lee YA, Meyers T, Matsuo K, Ito H, Vineis P, Stucker I, Boffetta P, Brennan P, Christiani DC, Diao N, Hong YC, Landi MT, Morgenstern H, Schwartz AG, Rennert G, Saliba W, McLaughlin JR, Harris CC, Orlow I, Barros Dios JM, Ruano Ravina A, Siemiatycki J, Koushik A, Cote M, Lazarus P, Fernandez-Tardon G, Tardon A, Le Marchand L, Brenner H, Saum KU, Duell EJ, Andrew AS, Consonni D, Olsson A, Hung RJ, Straif K.
Alcohol consumption and lung cancer risk: A pooled analysis from the International Lung Cancer Consortium and the SYNERGY study.
Cancer Epidemiology 2019; 58:25-32.

Quinzler R, Freitag MH, Wiese B, Beyer M, Brenner H, Dahlhaus A, Döring A, Freund T, Heier M, Knopf H, Luppa M, Prokein J, Riedel-Heller SG, Schäfer I, Scheidt-Nave C, Scherer M, Schöttker B, Szecsenyi J, Thürmann P, van den Bussche H, Gensichen J, Haefeli WE.
A novel superior medication-based chronic disease score predicted all-cause mortality in independent geriatric cohorts.
Journal of Clinical Epidemiology 2019; 105:112-124.

Hohls JK, Wild B, Heider D, Brenner H, Böhlen F, Saum KU, Schöttker B, Matschinger H, Haefeli WE, König HH, Hajek A.
Association of generalized anxiety symptoms and panic with health care costs in older age – Results from the ESTHER cohort study.
Journal of Affective Disorders 2019; 245:978-986.

Gies A, Cuk K, Schrotz-King P, Brenner H.
Combination of different fecal immunochemical tests in colorectal cancer screening: Any gain in diagnostic performance?
Cancers 2019; 11:120.

Gündert M, Edelmann D, Benner A, Jansen L, Jia M, Walter V, Knebel P, Herpel E, Chang-Claude J, Hoffmeister M, Brenner H, Burwinkel B.
Genome-wide DNA methylation analysis reveals a prognostic classifier for non-metastatic colorectal cancer (ProMCol classifier).
Gut 2019; 68:101-110.

Huang L, Jansen L, Balavarca Y, Molina-Montes E, Babaei M, van der Geest L, Lemmens V, Van Eycken L, De Schutter H, Johannesen TB, Fristrup CW, Mortensen MB, Zakelj MP, Zadnik V, Becker N, Hackert T, Mägi M, Cassetti T, Sassatelli R, Grützmann R, Merkel S, Goncalves AF, Bento MJ, Hegyi P, Lakatos G, Szentesi A, Moreau M, van de Velde T, Broeks A, Sant M, Minicozzi P, Mazzaferro V, Real FX, Carrato A, Molero X, Besselink MG, Malats N, Büchler MW, Schrotz-King P, Brenner H.
Resection of pancreatic cancer in Europe and the US: an international large-scale study highlighting large variations.
Gut 2019; 68:130-139.

Doege D, Thong MSY, Koch-Gallenkamp L, Bertram H, Eberle A, Holleczek B, Waldeyer-Sauerland M, Waldmann A, Zeissig SR, Brenner H, Arndt V.
The role of psychosocial resources for long-term breast, colorectal and prostate cancer survivors: Prevalence and associations with health-related quality of life.
Supportive Care in Cancer 2019; 27:275-286.

Hoffmeister M, Holleczek B, Stock C, Zwink N, Stolz T, Stegmaier C, Brenner H.
Utilization and determinants of follow-up colonoscopies within 6 years after screening colonoscopy: prospective cohort study.
International Journal of Cancer 2019; 144:402-410.

Weigl K, Tikk K, Hoffmeister M, De Toni EN, Hampe J, Kolligs F, Klug SJ, Mansmann U, Nasseh D, Radlovic J, Schwab M, Schweigler D, Stephan A, Brenner H.
A web-based survey among adults aged 40-54 years was time-effective and yielded stable response patterns.
Journal of Clinical Epidemiology 2019; 105:10-18.

Campa D, Matarazzi M, Greenhalf W, Bijlsma M, Saum KU,..., Valsuani C, Vashist YK, Brenner H, Canzian F.
Genetic determinants of telomere length and risk of pancreatic cancer: a PANDoRA study.
International Journal of Cancer 2019; 144:1275-1283.

Schöttker B, Hagen L, Zhang Y, Gào X, Holleczek B, Gao X, Brenner H.
Serum 25-hydroxyvitamin D levels as an ageing marker. Strong associations with age and all-cause mortality independent from telomere length, epigenetic age acceleration and 8-isoprostane levels.
Journal of Gerontology: Medical Sciences 2019; 74:121-128.

Mavaddat N, Michailidou K, Dennis J, Lush M, Fachal L,..., Arndt V,..., Brenner H,..., Kraft P, Garcia-Closas M, Simard J, Easton DF.
Polygenic risk scores for prediction of breast cancer and breast cancer subtypes.
The American Journal of Human Genetics 2019; 104:21-34.
Travis RC, Perez-Cornago A, Appleby PN, Albanes D, Joshu CE, Lutsey PL, Mondul AM, Platz EA, Weinstein SJ, Layne TM, Helzlsouer KJ, Visvanathan K, Palli D, Peeters PH, Bueno-de-Mesquita B, Trichopoulou A, Gunter MJ, Tsilidis KK, Sanchez MJ, Olsen A, Brenner H, Schöttker B, Perna L, Holleczek B, Knekt P, Rissanen H, Yeap BB, Flicker L, Almeida OP, Wong YYE, Chan JM, Giovannucci EL, Stampfer MJ, Ursin G, Gislefoss RE, Bjorge T, Meyer HE, Blomhoff R, Tsugane S, Sawada N, English DR, Eyles DW, Heath AK, Williamson EJ, Manjer J, Malm J, Almquist M, Le Marchand L, Haiman CA, Wilkens LR, Schenk JM, Tangen CM, Black A, Cook MB, Huang WY, Ziegler RG, Martin RM, Hamdy FC, Donovan JL, Neal DE, Touvier M, Hercberg S, Galan P, Deschasaux M, Key TJ, Allen NE.
A collaborative analysis of individual participant data from 19 prospective studies assesses circulating vitamin D and prostate cancer risk.
Cancer Research 2019; 79:274-285.

Caputo M, Horn J, Karch A, Akmatov M, Becher H, Braun B, Brenner H, Castell S, Fischer B, Giani G, Günther K, Hoffmann B, Jöckel KH, Keil T, Klüppelholz B, Krist L, Leitzmann MF, Lieb W, Linseisen J, Meisinger C, Moebus S, Obi N, Pischon T, Schipf S, Schmidt B, Sievers C, Steinbrecher A, Völzke H, Mikolajczyk R.
Herpes zoster incidence in Germany – an indirect validation study for self-reported disease data from pretest studies of the population-based German National Cohort.
BMC Infectious Diseases 2019; 19:99.

Möllers T, Perna L, Ihle P, Schubert I, Bauer J, Brenner H.
Factors associated with length of stay in hospital patients with and without dementia.
Journal of Alzheimer's Disease 2019; 67:1055-1065.

Rahbari NN*, Carr PR*, Jansen L, Chang-Claude J, Weitz J, Hoffmeister M, Brenner H.
Time of metastasis and outcome in colorectal cancer.
Annals of Surgery 2019; 269:494-502.
*contributed equally

Raina P, Gilsing A, Freisling H, van den Heuvel E, Sohel N, Jenab M, Ferrari P, Tjonneland A, Benetou V, Picavet S, Eriksson S, Schöttker B, Brenner H, Saum KU, Perna L, Wilsgaard T, Trichopoulou A, Boffetta P, Griffith L.
The combined effect of cancer and cardio-metabolic conditions on the mortality burden in older adults.
Journals of Gerontology: Medical Sciences 2019; 74:366-372.

Schmit SL, Edlund CK, Schumacher FR, Gong J, Harrison TA,..., Arndt V,..., Brenner H,..., Casey G, Hsu L, Conti DV, Gruber SB.
Novel common genetic susceptibility loci for colorectal cancer.
Journal of the National Cancer Institute 2019; 111:djy099.

Logan C, Weiss J, König W, Stahl B, Carr P, Brenner H, Rothenbacher D, Genuneit J.
Soluble CD14 concentration in human breast milk and its potential role in child atopic dermatitis: Results of the Ulm Birth Cohort Studies.
Clinical & Experimental Allergy 2019; 49:199-206.

Brenner H, Gies A.
Immunologische Stuhlbluttests – welche Verbesserungen gegenüber dem Guajak basierten Test?
Der Gastroenterologe 2019; 14:6-13, sowie Best Practice Onkologie 2019; 5:190-194.

Jiang R, Poschet G, Owen R, Celik M, Jansen L, Hell R, Hoffmeister M, Brenner H, Chang-Claude J.
Serum concentration of genistein, luteolin and colorectal cancer prognosis.
Nutrients 2019; 11:600.

Meyer ML, Lin FC, Jaensch A, Mons U, Hahmann H, Koenig W, Brenner H, Rothenbacher D.
Multi-state models of transitions in depression and anxiety symptom severity and cardiovascular events in patients with coronary heart disease.
PloS ONE 2019; 14:e0213334.

Bläker H, Alwers E, Arnold A, Herpel E, Tagscherer KE, Roth W, Jansen L, Walter V, Kloor M, Chang-Claude J, Brenner H, Hoffmeister M.
The association between mutations in BRAF and colorectal cancer-specific survival depends on microsatellite status and tumor stage.
Clinical Gastroenterology and Hepatology 2019; 17:455-462.

Wild B, Herzog W, Schellberg D, Böhlen F, Brenner H, Saum KU, Maatouk I.
A short intervention targeting psychosomatic care in older adults with complex health care needs – results of a randomized controlled trial.
International Journal of Geriatric Psychiatry 2019; 34:272-279.

Krilaviciute A, Leja M, Kopp-Schneider A, Barash O, Khatib S, Amal H, Broza Y, Polaka I, Parshutin S, Rudule A, Haick H, Brenner H.
Associations of diet and lifestyle factors with common volatile organic compounds in exhaled breath of average-risk individuals.
Journal of Breath Research 2019; 13:026006.

Erben V, Carr PR, Holleczek B, Stegmaier C, Hoffmeister M, Brenner H.
Strong associations of a healthy lifestyle with all stages of colorectal carcinogenesis: results from a large cohort of participants of screening colonoscopy.
International Journal of Cancer 2019; 144:2135-2143.

Jiang X, Finucane H, Schumacher F, Schmit S, Tyrer J,..., Brenner H,..., Hoffmeister M,..., Lane J, Saxena R, Kraft P, Lindstrom S.
Shared heritability and functional enrichment across six solid cancers.
Nature Communications 2019; 10:431.

Gào X, Zhang Y, Burwinkel B, Xuan Y, Holleczek B, Brenner H, Schöttker B.
The associations of DNA methylation alterations in oxidative stress related genes with cancer incidence and mortality outcomes: A population-based cohort study.
Clinical Epigenetics 2019; 11:14.
Kather JN, Krisam J, Charoentong P, Luedde T, Herpel E, Weis CA, Gaiser T, Marx A, Valous NA, Ferber D, Jansen L, Reyes-Aldasoro CC, Zörnig I, Jäger D, Brenner H, Chang-Claude J, Hoffmeister M, Halama N.
Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study.
PLoS Medicine 2019; 16:e1002730.

Brunssen A, Jansen L, Eisemann N, Waldmann A, Weberpals J, Kraywinkel K, Eberle A, Holleczek B, Zeissig SR, Brenner H, Katalinic K, GEKID Cancer Survival Working Group.
A population-based registry study on relative survival from melanoma in Germany stratified by tumor thickness for each histologic subtype.
Journal of the American Academy of Dermatology 2019; 80:938-946.

Amitay E, Gies A, Weigl K, Brenner H.
Fecal immunochemical tests for colorectal cancer screening: Is fecal sampling from multiple sites necessary?
Cancers 2019; 11:400.

Amitay E, Cuk K, Niedermaier T, Weigl K, Brenner H.
Factors associated with false-positive fecal immunochemical tests in a large German colorectal cancer screening study.
International Journal of Cancer 2019; 144:2419-2427.

Böhlen F, Freigofas J, Herzog W, Meid A, Saum KU, Schöttker B, Brenner H, Haefeli W, Wild B.
Evidence for underuse and overuse of antidepressants in older adults: Results of a large population-based study.
International Journal of Geriatric Psychiatry 2019; 34:539-547.

Tian Y, Kharazmi E, Sundquist K, Sundquist J, Brenner H, Fallah M.
Familial colorectal cancer risk in half-siblings and siblings: nationwide cohort study.
BMJ 2019; 364:1803.

Hellmuth C, Kirchberg FF, Brandt S, Moß A, Walter V, Rothenbacher D, Brenner H, Grote V, Gruszfeld D, Socha P, Closa-Monasterolo R, Escribano J, Luque V, Verduci E, Mariani B, Langhendries JP, Poncelet P, Heinrich J, Lehmann I, Standl M, Uhl O, Koletzko B, Thiering E, Wabitsch M.
An individual participant data meta-analysis on metabolomics profiles for obesity and insulin resistance in European children.
Scientific Reports 2019; 9:5053.

Huang L, Balavarca Y, van der Geest L, Lemmens V, Van Eycken L, De Schutter H, Johannesen TB, Zadnik V, Primic-Zakelj M, Mägi M, Grützmann R, Besselink MG, Schrotz-King P, Brenner H, Jansen L.
Development and validation of a prognostic model to predict the prognosis of patients who underwent chemotherapy and resection of pancreatic adenocarcinoma: a large international population-based cohort study.
BMC Medicine 2019; 17:66.

Xuan Y, Bobak M, Anusruti A, Jansen EHJM, Pajak A, Tamosiunas A, Saum KU, Holleczek B, Gao X, Brenner H, Schöttker B.
Association of serum markers of oxidative stress with myocardinal infarction and stroke: Pooled results from four large European cohort studies.
European Journal of Epidemiology 2019; 34:471-481.

Ferreira MA, Al-Ejeh F, Campa D, Gamazon E, Parsons M,..., Arndt V, Brenner H,..., Caldés T, de la Hoya M, BCFR Investigators, GC-HBOC Collaborators.
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer.
Nature Communications 2019; 10:1741.

Gao X, Gào X, Zhang Y, Holleczek B, Schöttker B, Brenner H.
Oxidative stress and epigenetic mortality risk score: associations with all-cause mortality among elderly people.
European Journal of Epidemiology 2019; 34:451-462.

Thomas AM, Manghi P, Asnicar F, Pasolli E, Armanini F,..., Schrotz-King P,..., Brenner H,..., Rescigno M, Waldron L, Naccarati A, Segata N.
Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation.
Nature Medicine 2019; 25:667-678.

Wirbel J, Pyl PT, Kartal E, Zych K, Kashani A,..., Brenner H, Arumugam M, Bork P, Zeller G.
Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer.
Nature Medicine 2019; 25:679-689.

Chen C, Stock C, Hoffmeister M, Brenner H.
Optimal age for screening colonoscopy: a modeling study.
Gastrointestinal Endoscopy 2019; 89:1017-1025.

Gregson J, Kaptoge S, Bolton T, Pennells L, Willeit P,..., Arndt V,..., Brenner H,..., Thompson SG, Danesh J, Di Angelantonio E, Meade T, for the Emerging Risk Factors Collaboration.
Cardiovascular risk factors associated with venous thromboembolism.
JAMA Cardiology 2019; 4:163-173.

Doege D, Thong MSY, Koch-Gallenkamp L, Bertram H, Eberle A, Holleczek B, Pritzkuleit R, Waldeyer-Sauerland M, Waldmann A, Zeissig SR, Jansen L, Brenner H, Arndt V.
Health-related quality of life in long-term disease-free breast cancer survivors versus female population controls in Germany.
Breast Cancer Research and Treatment 2019; 175:499-510.

Law P, Timofeeva M, Fernandez-Rozadilla C, Broderick P, Studd J,..., Butterbach K, Chang-Claude J, Hoffmeister M, Brenner H,..., Cheadle J, Tomlinson I, Houlston R, Dunlop M.
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
Nature Communications 2019; 10:2154.

Di Credico G, Edefonti V, Polesel J, Pauli F, Torelli N,..., Brenner H,..., Boffetta P, Hashibe M, Lee YCA, Dal Maso L.
Joint effects of intensity and duration of cigarette smoking on the risk of head and neck cancer: a bivariate spline model approach.
Oral Oncology 2019; 94:47-57.

Amitay EL, Carr PR, Jansen L, Walter V, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.
Association of aspirin and non-steroidal anti-inflammatory drugs and colorectal cancer risk by molecular subtypes.
Journal of the National Cancer Institute 2019; 111:djy170.

Zaimenko I, Jaeger C, Brenner H, Chang-Claude J, Hoffmeister M, Grötzinger C, Detjen K, Burock S, Schmitt CA, Stein U, Lisec J.
Non-invasive metastasis prognosis from plasma metabolites in stage II colorectal cancer patients: the DACHS study.
International Journal of Cancer 2019; 145:221-231.

Gào X, Wilsgaard T, Jansen EHJM, Holleczek B, Zhang Y, Xuan Y, Anusruti A, Brenner H, Schöttker B.
Pre-diagnostic derivatives of reactive oxygen metabolites and the occurrence of lung, colorectal, breast and prostate cancer: An individual participant data meta-analysis of two large population-based studies.
International Journal of Cancer 2019; 145:49-57.

Kar SP, Andrulis IL, Brenner H, Burgess S, Chang-Claude J, Considine D, Dörk T, Evans GR, Gago-Dominguez M, Giles GG, Hartman M, Huo D, Kaaks R, Li J, Lophatananon A, Margolin S, Milne RL, Muir KR, Olsson H, Punie K, Radice P, Simard J, Tamimi RM, Van Nieuwenhuysen E, Wendt C, Zheng W, Pharoah PDP.
The association between weight at birth and breast cancer risk revisited using Mendelian randomisation.
European Journal of Epidemiology 2019; 34:591-600.

Bien S, Su YR, Conti DV, Harrison TA, Qu C,..., Brenner H,..., Hoffmeister M,..., Gruber SB, Hsu L, Zhang W, Peters U.
Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer.
Human Genetics 2019; 138:307-326.

Chen C, Stock C, Jansen L, Chang-Claude J, Hoffmeister M, Brenner H.
Trends in colonoscopy and fecal occult blood test use after the introduction of dual screening offers in Germany: Results from a large population-based study, 2003-2016.
Preventive Medicine 2019; 123:333-340.

Fiorito G, McCrory C, Robinson O, Carmeli C, Rosales CO, Zhang Y,..., Brenner H,..., Elliot P, Stringhini S, Vineis P, Polidoro S, and the Lifepath consortium.
Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis.
Aging 2019; 11:2045-2070.

Brenner H, Calderazzo S, Seufferlein T, Ludwig L, Dikopoulos N, Mangold J, Böck W, Stolz T, Eisenbach T, Block T, Kopp-Schneider A, Czock D, Tikk K.
Effect of a single aspirin dose prior to fecal immunochemical testing on test sensitivity for detecting advanced colorectal neoplasms: A randomized clinical trial.
JAMA 2019; 321:1686-1692.

Gào X, Holleczek B, Cuk K, Zhang Y, Anusruti A, Xuan Y, Xu Y, Brenner H, Schöttker B.
Investigation on potential associations of oxidatively generated DNA/RNA damage with lung, colorectal, breast, prostate and total cancer incidence.
Scientific Reports 2019; 9:7109.

NCD Risk Factor Collaboration (NCD-RisC).*
Rising rural body-mass index is the main driver of the global obesity epidemic in adults.
Nature 2019; 569:260-264.
*Collaborators on behalf of the ESTHER study: Brenner H, Saum KU, Schöttker B

Wuttke M, Li Y, Li M, Sieber KB, Feitosa MF,..., Brenner H,..., Schöttker B,..., Scholz M, Teumer A, Köttgen A, Pattaro C.
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
Nature Genetics 2019; 51:957-972.

Holleczek B, Stegmaier C, Radosa JC, Solomayer EF, Brenner H.
Risk of loco-regional recurrence and distant metastases of patients with invasive breast cancer up to ten years after diagnosis – results from a registry-based study from Germany.
BMC Cancer 2019; 19:520.

Thong MSY, Koch-Gallenkamp L, Jansen L, Bertram H, Eberle A, Holleczek B, Waldeyer-Sauerland M, Waldmann A, Zeissig SR, Brenner H, Arndt V.
Age-specific health-related quality of life in long-term and very long-term colorectal cancer survivors versus population controls – A population-based study.
Acta Oncologica 2019; 58:801-810.

Arndt V, Koch-Gallenkamp L, Bertram H, Eberle A, Holleczek B, Pritzkuleit R, Waldeyer-Sauerland M, Waldmann A, Zeissig SR, Doege D, Thong MSY, Brenner H.
Return to work after cancer. A multi-regional population-based study from Germany.
Acta Oncologica 2019; 58:811-818.

Obazee O, Archibugi L, Andriulli A, Soucek P, Malecka-Panas E,..., Brenner H,..., Vodicka P, Tjaden C, Iskierka-Jazdzewska E, Canzian F.
Germline BRCA2 K3326X and CHEK2 I157T mutations increase risk for sporadic pancreatic ductal adenocarcinoma.
International Journal of Cancer 2019; 145:686-693.

Möllers T, Stocker H, Wei W, Perna L, Brenner H.
Length of hospital stay and dementia: a systematic review of observational studies.
International Journal of Geriatric Psychiatry 2019; 34:8-21.

Wild CP, Espina C, Bauld L, Bonanni B, Brenner H, Brown K, Dillner J, Forman D, Kampman E, Nilbert M, Steindorf K, Storm H, Vineis P, Baumann M, Schüz J.
Cancer Prevention Europe.
Molecular Oncology 2019; 13:528-534.

Alwers E, Bläker H, Walter V, Jansen L, Kloor M, Arnold A, Sieber-Frank J, Herpel E, Tagscherer KE, Roth W, Chang-Claude J, Brenner H, Hoffmeister M.
External validation of molecular subtype classifications of colorectal cancer based on microsatellite instability, CIMP, BRAF and KRAS.
BMC Cancer 2019; 19:681.

Raut JR, Guan Z, Schrotz-King P, Brenner H.
Whole-blood DNA methylation markers for risk stratification in colorectal cancer screening: A systematic review.
Cancers 2019; 11:912.

Jansen H, Jaensch A, Schöttker B, Dallmeier D, Schmucker R, Brenner H, Koenig W, Rothenbacher D.
Repeat measurements of high sensitivity troponins for the prediction of recurrent cardiovascular events in patients with established coronary heart disease – an analysis from the KAROLA study.
Journal of the American Heart Association 2019; 8:e011882.

Gies A, Gruner LF, Schrotz-King P, Brenner H.
Effect of imperfect compliance with instructions for fecal sample collection on diagnostic performance of 9 fecal immunochemical tests.
Clinical Gastroenterology and Hepatology 2019; 17:1829-1839.

Broza YY, Khatib S, Gharra A, Krilaviciute A, Amal H, Polaka I, Parshutin S, Kikuste I, Gasenko E, Skapars R, Brenner H, Leja M, Haick H.
Screening for gastric cancer using exhaled breath samples.
British Journal of Surgery 2019; 106:1122-1125.

Khetan P, Boffetta P, Luce D, Stucker I, Curado MP, Menezes A, Wunsch-Filho V, Ahrens W, Lagiou P, Serraino D, Richiardi L, Kjaerheim K, Conway D, Thomson P, Muscat J, Mates D, Ramroth H, Menvielle G, Vaughan TL, Brenner H, Lee YA, La Vecchia C, Hashibe M, Hashim D.
Occupations and the risk of head and neck cancer: A pooled analysis of the International Head and Neck Cancer Epidemiology (INHANCE) Consortium.
Journal of Occupational and Environmental Medicine 2019; 61:397-404.

Kather JN, Pearson AT, Halama N, Jäger D, Krause J, Loosen SH, Marx A, Boor P, Tacke F, Neumann UP, Grabsch HI, Yoshikawa T, Brenner H, Chang-Claude J, Hoffmeister M, Trautwein C, Luedde T.
Deep learning can predict microsatellite instability direct from histology in gastrointestinal cancer.
Nature Medicine 2019; 25:1054-1056.

Pulte D, Weberpals J, Jansen L, Brenner H.
Changes in population-level survival for advanced solid malignancies with new treatment options in the second decade of the 21st century.
Cancer 2019; 125:2656-2665.

Geijsen AJMR, van Roekel EH, van Duijnhoven FJB, Achaintre D, Bachleitner-Hofmann T,..., Brenner H,..., Hoffmeister M,..., Schrotz-King P,..., Ulrich AB, Ulrich CM, Weijenberg MP, Kok DE.
Plasma metabolites associated with colorectal cancer: A discovery-replication strategy.
International Journal of Cancer 2019; 145:1221-1231.

Carr PR, Banbury B, Berndt SI, Campbell PT, Chang-Claude J, Hayes RB, Howard BV, Jansen L, Jacobs E, Lane DS, Nishihara R, Ogino S, Phipps AI, Slattery ML, Stefanick ML, Wallace R, Walter V, White E, Wu K, Peters U, Chan AT, Newcomb PA, Brenner H, Hoffmeister M.
Association between intake of red and processed meat and survival in patients with colorectal cancer in a pooled analysis.
Clinical Gastroenterology and Hepatology 2019; 17:1561-1570.

Campa D, Martino A, Macauda A, Dudzinski M, Suska A,..., Brenner H,..., Zaucha JM, Andersen V, Zawirska D, Canzian F.
Genetic polymorphisms in genes of class switch recombination and multiple myeloma risk and survival: an IMMEnSE study.
Leukemia and Lymphoma 2019; 60:1803-1811.

Patel RS, Tragante V, Schmidt AF, McCubrey RO, Holmes MV,..., Breitling LP,..., Mons U,..., Brenner H,..., Wallentin L, Samani NJ, Hingorani AD, Asselbergs FW.
Subsequent event risk in individuals with established coronary heart disease: design and rationale of the GENIUS-CHD consortium.
Circulation: Genomic and Precision Medicine 2019; 12:e002470.

Patel RS, Schmidt AF, Tragante V, McCubrey RO, Holmes MV,..., Breitling L,..., Mons U,..., Brenner H,..., Horne BD, Samani NJ, Hingorani AD, Asselbergs FW.
Association of chromosome 9p21 with subsequent coronary heart disease events: a GENIUS-CHD study of individual participant data.
Circulation: Genomic and Precision Medicine 2019; 12:e002471.

Ran T, Cheng CY, Misselwitz B, Brenner H, Ubels J, Schlander M.
Cost-effectiveness of colorectal cancer screening strategies – A systematic review.
Clinical Gastroenterology and Hepatology 2019; 17:1969-1981.

Logan CA, Siziba LP, König W, Carr P, Brenner H, Rothenbacher D, Genuneit J.
Leptin in human milk and child body mass index: Results of the Ulm Birth Cohort Studies.
Nutrients 2019; 11:1883.

Perna L, Wahl HW, Weberpals J, Jansen L, Mons U, Schöttker B, Brenner H.
Incident depression and mortality among people with different types of dementia: Results from a longitudinal cohort study.
Social Psychiatry and Psychiatric Epidemiology 2019; 54:793-801.

Hung RJ, Spitz MR, Houlston RS, Schwartz AG, Field JK,..., Brenner H,..., Christiani DC, Amos CI, Yang P, Gorlova OY.
Lung cancer risk in never smokers of European descent is associated with genetic variation in the 5P15.33 TERT-CLPTM1L region.
Journal of Thoracic Oncology 2019; 14:1360-1369.

Xuan Y, Gào X, Anusruti A, Holleczek B, Jansen EHJM, Muhlack DC, Brenner H, Schöttker B.
Association of serum markers of oxidative stress with incident major cardiovascular events, cancer incidence and all-cause mortality in type 2 diabetes patients: Pooled results from two cohort studies.
Diabetes Care 2019; 42:1436-1445.

Jia M, Zhang Y, Jansen L, Walter V, Edelmann D, Gündert M, Tagscherer K, Roth W, Bewerunge-Hudler M, Herpel E, Kloor M, Ulrich A, Burwinkel B, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M.
A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival.
Clinical Epigenetics 2019; 11:109.

Peng L, Balavarca Y, Weigl K, Hoffmeister M, Brenner H.
Head-to-head comparison of the performance of 17 risk models for predicting presence of advanced neoplasms in colorectal cancer screening.
American Journal of Gastroenterology 2019; 114:1520-1530.

Boakye D, Walter V, Martens U, Chang-Claude J, Hoffmeister M, Jansen L, Brenner H.
Treatment selection bias for chemotherapy persists in colorectal cancer patient cohort studies even in comprehensive propensity score analyses.
Clinical Epidemiology 2019; 11:821-832.

Cardoso R, Niedermaier T, Chen C, Hoffmeister M, Brenner H.
Colonoscopy and sigmoidoscopy use among the average-risk population for colorectal cancer: a systematic review and trend analysis.
Cancer Prevention Research 2019; 12:617-630.

Gào X, Xuan Y, Benner A, Anusruti A, Brenner H, Schöttker B.
Nitric oxide metabolites and lung cancer incidence: A matched case-control study nested in the ESTHER cohort.
Oxidative Medicine and Cellular Longevity 2019; 6470950.

Wang X, Dai JY, Albanes D, Arndt V, Berndt SI,..., Brenner H,..., Hoffmeister M, Wu AH, Gruber SB, Peters U, White E.
Mendelian randomization analysis of C-reactive protein on colorectal cancer risk.
International Journal of Epidemiology 2019; 48:767-780.

Shu X, Wu L, Khankari NK, Shu XO, Wang TJ, Michailidou K, Bolla MK, Wang Q, Dennis J, Milne RL, Schmidt MK, Pharoah PDP, Andrulis IL, Hunter DJ, Simard J, Easton DF, Zheng W, Breast Cancer Association Consortium*.
Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis.
International Journal of Epidemiology 2019; 48:795-806.
*Co-authors on behalf of the ESTHER study: Arndt V, Brenner H

Walter V, Boakye D, Weberpals J, Jansen L, Haefeli WE, Martens UM, Knebel P, Chang-Claude J, Hoffmeister M, Brenner H.
Decreasing use of chemotherapy in older stage III colon cancer patients irrespective of comorbidities.
Journal of the National Comprehensive Cancer Network 2019; 17:1089-1099.

Adam S, Koch-Gallenkamp L, Bertram H, Eberle A, Holleczek B, Pritzkuleit R, Waldeyer-Sauerland M, Waldmann A, Zeissig SR, Rohrmann S, Brenner H, Arndt V.
Health-related quality of life in long-term survivors with localised prostate cancer by therapy – results from a population-based study.
European Journal of Cancer Care 2019; 28:e13076.

The WHO CVD Risk Chart Working Group.*
World Health Organization (WHO) cardiovascular disease risk charts: revised models to estimate risk in 21 global regions.
The Lancet Global Health 2019; 7:e1332-1345.
*Co-authors on behalf of the ESTHER study: Brenner H, Schöttker B

Shepshelovich D, Xu W, Lu L, Fares A, Yang P, Christiani D, Zhang J, Shiraishi K, Ryan BM, Chen C, Schwartz AG, Tardon A, Wu X, Schabath MB, Teare MD, Le Marchand L, Zhang ZF, Field JK, Brenner H, Daio N, Xie J, Kohno T, Harris CC, Wenzlaff AS, Fernandez-Tardon G, Ye Y, Taylor F, Wilkens LR, Davies M, Liu Y, Barnett MJ, Goodman GE, Morgenstern H, Holleczek B, Brown MC, Hung R, Liu G.
Body mass index (BMI), BMI change, and overall survival in patients with SCLC and NSCLC: A pooled analysis of the International Lung Cancer Consortium.
Journal of Thoracic Oncology 2019; 14:1594-1607.

Haffa M, Lin T, Holowatyj AN, Kratz M, Toth R, Benner A, Gigic B, Habermann N, Schrotz-King P, Böhm J, Brenner H, Schneider M, Ulrich A, Herpel E, Schirmacher P, Straub BK, Nattenmüller J, Kauczor HU, Ball CR, Ulrich CM, Glimm H, Scherer D.
Transcriptome profiling of adipose tissue reveals depot-specific metabolic alterations among patients with colorectal cancer.
The Journal of Clinical Endocrinology & Metabolism 2019; 104:5225-5237.

Teumer A, Li Y, Ghasemi S, Prins B, Wuttke M,..., Brenner H,..., Schöttker B,..., Kottgen A, Gerstner L, Chen M, Grundner-Culemann F.
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
Nature Communications 2019; 10:4130.

Dörk T, Peterlongo P, Mannermaa A, Bolla MK, Wang Q,..., Brenner H,..., Pharoah PDP, Schindler D, Devilee P, Easton DF.
Two truncating variants in FANCC and breast cancer risk.
Scientific Reports 2019; 9:12524.

Boakye D, Jansen L, Schneider M, Chang-Claude J, Hoffmeister M, Brenner H.
Personalizing the prediction of colorectal cancer prognosis by incorporating comorbidities and functional status into prognostic nomograms.
Cancers 2019; 11:1435.

Bhardwaj M, Gies A, Weigl K, Tikk K, Benner A, Schrotz-King P, Borchers CH, Brenner H.
Evaluation and validation of plasma proteins using two different protein detection methods for early detection of colorectal cancer.
Cancers 2019; 11:1426.

Hu C, Schöttker B, Venisse N, Limousi F, Saulnier PJ, Albouy-Llaty M, Dupuis A, Brenner H, Migeot V, Hadjadj S.
Bisphenol A, chlorinated dervatives of Bisphenol A and occurrence of myocardinal infarction in patients with type 2 diabetes: nested case-control studies in two European cohorts.
Environmental Science & Technology 2019; 53:9876-9883.

Thong MSY, Doege D, Koch-Gallenkamp L, Bertram H, Eberle A, Holleczek B, Waldeyer-Sauerland M, Waldmann A, Zeissig SR, Brenner H, Arndt V.
Age at diagnosis and sex are associated with long-term deficits in disease-specific health-related quality of life of survivors of colon and rectal cancer: a population-based study.
Diseases of the Colon & Rectum 2019; 62:1294-1304.

Brenner H, Gies A, Selby K.
Overestimated sensitivity of fecal immunochemical tests in screening cohorts with registry-based follow-up.
American Journal of Gastroenterology 2019; 114:1795-1801.

Heißer T, Peng L, Weigl K, Hoffmeister M, Brenner H.
Outcomes at follow-up of a negative colonoscopy in average-risk population: a systematic review and meta-analysis.
BMJ 2019; 367:16109.

Selby K, Levine EH, Doan C, Gies A, Brenner H, Quesenberry C, Lee JK, Corley DA.
Effect of sex, age and positivity threshold on fecal immunochemical test accuracy: a systematic review and meta-analysis.
Gastroenterology 2019; 157:1494-1505.

Knüppel S, Clemens M, Conrad J, Gastell S, Michels KB, Leitzmann M, Krist L, Pischon T, Krause G, Ahrens W, Ebert N, Jöckel KH, Kluttig A, Obi N, Kaaks R, Lieb W, Schipf S, Brenner H, Heuer T, Harttig U, Linseisen J, Nöthlings U, Boeing H.
Design and characterization of dietary assessment in the German National Cohort.
European Journal of Clinical Nutrition 2019; 73:1480-1491.
Pardini B, Corrado A, Paolicchi E, Cugliari G, Berndt SI,..., Brenner H,..., Hoffmeister M,..., Gemignani F, Peters U, Naccarati A, Landi S.
DNA repair and cancer in colon and rectum: novel players in genetic susceptibility.
International Journal of Cancer 2019; 146:363-372.
Ooi BNS, Loh H, Ho PJ, Milne R, Giles G, Gao C, Kraft P, John EM, Swerdlow A, Brenner H, Wu AH, Haiman C, Evans DG, Zheng W, Fasching P, Castelao JE, Kwong A, Xia S, Czene K, Hall P, Dunning A, Easton DF, Hartman M, Li J.
The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis.
International Journal of Epidemiology 2019; 48:781-794.

Weigl K, Chang-Claude J, Hsu L, Hoffmeister M, Brenner H.
Establishing a valid approach for estimating familial risk of cancer explained by common genetic variants.
International Journal of Cancer 2019; 146:68-75.
Pennells L, Kaptoge S, Wood A, Sweeting M, Zhao X,..., Brenner H,..., D'Agostino Sr RBD, Thompson SG, Danesh J, Di Angelantonio E, on behalf of the Emerging Risk Factors Collaboration.
Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.
European Heart Journal 2019; 40:621-631.
Escala-Garcia M, Guo Q, Dörk T, Canisius S, Keeman R,..., Arndt V,..., Brenner H,..., Holleczek B,..., Nevanlinna H, Eccles DM, Pharoah PDP, Schmidt MK.
Genome-wide association study of germline variants and breast cancer-specific mortality.
British Journal of Cancer 2019; 120:647-657.
Inker LA, Grams ME, Levey AS, Coresh J, Cirillo M,..., Kovesdy CP, Woodward M, Levin A, CKD Prognosis Consortium.*
Relationship of estimated GFR and albuminuria to concurrent laboratory abnormalities: an indivicual participant data meta-analysis in a global consortium.
American Journal of Kidney Diseases 2019; 73:206-217.
*Collaborators on behalf of the ESTHER study: Brenner H, Rothenbacher D, Schöttker B, Saum KU
Hohls JK, König HH, Heider D, Brenner H, Böhlen F, Matschinger H, Saum KU, Schöttker B, Haefeli WE, Hajek A, Wild B.
Longitudinal association between panic disorder and health care costs in older adults.
Depress Anxiety 2019; 36:1135-1142.
Huyghe JR, Bien SA, Harrison TA, Kang HM, Chen S,..., Brenner H,..., Hoffmeister M,..., Nickerson DA, Gruber SB, Hsu L, Peters U.
Discovery of common and rare genetic risk variants for colorectal cancer.
Nature Genetics 2019; 51:76-87.
Neumeyer S, Popanda O, Edelmann D, Butterbach K, Toth C, Roth W, Bläker H, Jian R, Herpel E, Jäkel C, Schmezer P, Jansen L, Alwers E, Benner A, Burwinkel B, Hoffmeister M, Brenner H, Chang-Claude J.
Genome-wide DNA methylation differences according to oestrogen receptor beta status in colorectal cancer.
Epigenetics 2019; 14:477-493.
Adams CD, Richmond R, Ferreira DLS, Spiller W, Tan V,..., Brenner H,..., Pandha H, Thibodeau AN, Martin RM, PRACTICAL Consortium.
Circulating metabolic biomarkers of screen-detected prostate cancer in the ProtecT Study.
Cancer Epidemiology & Biomarkers 2019; 28:208-216.

Chang CP, Chang SC, Chuang SC, Berthiller J, Ferro G,..., Brenner H,..., Boffetta P, Zhang ZF, Hashibe M, Lee YA.
Age at start of using tobacco on the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium (INHANCE).
Cancer Epidemiology 2019; 63:101615.

Hoppe LK, Muhlack DC, Koenig W, Brenner H, Schöttker B.
The associations of diuretics and laxatives use with cardiovascular mortality. An individual patient-data meta-analysis of two large cohort studies.
Cardiovascular Drugs and Therapy 2019; 33:567-579.

Figlioli G, Bogliolo M, Catucci I, Caleca L, Lasheras SV,..., Arndt V,..., Brenner H,..., Couch F, Nevanlinna H, Surrallés J, Peterlongo P.
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer.
npj Breast Cancer 2019; 5:38.

Brunner FJ, Waldeyer C, Ojeda F, Salomaa V, Kee F,..., Brenner H,..., Omland T, Kuulasmaa K, Landmesser U, Blankenberg S.
Application of Non-HDL-Cholesterol for population-based cardiovascular risk stratification. Results from the Multinational Cardiovascular Risk Consortium.
Lancet 2019; 394:2173-2183.

Neumeyer S, Popanda O, Butterbach K, Edelmann D, Bläker H, Toth C, Roth W, Herpel E, Jäkel C, Schmezer P, Benner A, Burwinkel B, Hoffmeister M, Brenner H, Chang-Claude J.
DNA methylation profiling to explore colorectal tumor differences according to menopausal hormone therapy use in women.
Epigenomics 2019; 11:1765-1778.

Weigl K, Hsu L, Knebel P, Hoffmeister M, Timofeeva M, Farrington S, Dunlop M, Brenner H.
Head to head comparison of family history of colorectal cancer and a genetic risk score for colorectal cancer risk stratification.
Clinical and Translational Gastroenterology 2019; 10:e00106.

Wang X, O'Connell K, Jeon J, Song M, Hunter D, Hoffmeister M, Lin Y, Berndt S, Brenner H, Chan AT, Chang-Claude J, Gong J, Gunter MJ, Harrison TA, Hayes RB, Joshi A, Newcomb P, Schoen R, Slattery ML, Vargas A, Potter JD, Le Marchand L, Giovannucci E, White E, Hsu L, Peters U, Du M.
Combined effect of modifiable and non-modifiable risk factors for colorectal cancer risk in a pooled analysis of 11 population-based studies.
BMJ Open Gastroenterology 2019; 6:e000339.

Gunter MJ, Alhomoud S, Arnold M, Brenner H, Burn J, Casey G, Chan AT, Cross AJ, Giovannucci E, Hoover R, Houlston R, Jenkins M, Laurent-Puig P, Peters U, Ransohoff D, Riboli E, Sinha R, Stadler ZK, Brennan P, Chanock SJ.
Meeting report from the joint IARC-NCI international cancer seminar series: a
focus on colorectal cancer.
Annals of Oncology 2019; 30:510-519.

Yu H, Guan Z, Cuk K, Zhang Y, Brenner H.
Circulating microRNA biomarkers for lung cancer detection in East Asian populations.
Cancers 2019; 11:415.

Mukama T, Kharazmi E, Xing X, Sundquist K, Sundquist J, Brenner H, Fallah M.
Risk-adapted starting age of screening for relatives of breast cancer patients: Evidence to supplement current screening guidelines.
JAMA Oncology 2019; 6:68-74.

Raut J, Guan Z, Schrotz-King P, Brenner H.
Whole-blood DNA methylation markers for risk stratification in colorectal cancer screening: A systematic review.
Cancers 2019; 11:912.

Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Abate D,..., Brenner H,..., Schöttker B,..., Ziapour A, Zodpey S, Murray CJL.
Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017: A systematic analysis for the Global Burden of Disease Study.
JAMA Oncology 2019; 5:1749-1769.
Kar SP, Brenner H, Giles GG, Huo D, Milne RL, Rennert G, Simard J, Zheng W, Burgess S, Pharoah PDP.
Body mass index and the association between low-density lipoprotein cholesterol as predicted by HMGCR genetic variants and breast cancer risk.
International Journal of Epidemiology 2019; 48:1727-1730.

Abubakar M, Chang-Claude J, Raza Ali H, Chatterjee N, Coulson P, Daley F, Blows F, Benitez J, Milne R, Brenner H, Stegmaier C, Mannermaa A, Rudolph A, Sinn P, Couch FJ, Devilee P, Tollenaar RAEM, Seynaeve C, Figueroa J, Lissowska J, Hewitt S, Hooning MJ, Hollestelle A, Foekens R, Koppert LB, kConFab Investigators, Bolla MK, Wang Q, Jones ME, Schoemaker MJ, Keeman R, Easton DF, Swerdlow AJ, Sherman ME, Schmidt MK, Pharoah PD, Garcia-Closas M: Etiology of hormone receptor positive breast cancer differs by levels of histologic grade and proliferation. International Journal of Cancer 143 (4), 746-757, 2018. 

Babaei M, Jansen L, Balavarca Y, Sjovall A, Bos A, van de Velde T, Moreau M, Liberale G, Goncalves AF, Bento MJ, Ulrich CM, Schrotz-King P, Lemmens V, Glimelius B, Brenner H: Neoadjuvant Therapy in Rectal Cancer Patients With Clinical Stage II to III Across European Countries: Variations and Outcomes. Clinical Colorectal Cancer 17 (1), e129-e142, 2018. 

Babaei M, Balavarca Y, Jansen L, Lemmens V, van Erning FN, van Eycken L, Vaes E, Sjövall A, Glimelius B, Ulrich CM, Schrotz-King P, Brenner H: Administration of adjuvant chemotherapy for stage II-III colon cancer patients: a European population-based study. International Journal of Cancer 142 (7), 1480-1489, 2018. 

Behrens G*, Gredner T* (*equal contributions), Stock C, Brenner H**, Mons U** (equal contributions): Cancers due to excess weight, low physical activity, and unhealthy diet. Deutsches Aerzteblatt International 115 (35-36), 578-585, 2018. 

Braig S, Berger S, Rothenbacher D, Schmid S, Seufferlein T, Brenner H, Rothenbacher D, Gündel H: Time trends in dyspepsia and association with H. pylori and work-related stress - an observational study in white collar employees in 1996 and 2015. PLoS ONE 13 (6), e0199533, 2018. 

Braig S, Genuneit J, Walter V, Brandt S, Wabitsch M, Goldbeck L, Brenner H, Rothenbacher D: Screen time, physical activity and self-esteem in children: the Ulm Birth Cohort Study. International Journal of Environmental Research and Public Health 15 (6), E1275, 2018. 

Brenner H, Qian J, Werner S: Variation of diagnostic performance of fecal immunochemical testing for hemoglobin by sex and age: results from a large screening cohort. Clinical Epidemiology 10, 381-389, 2018. 

Buchele G, Gunther KP, Brenner H, Puhl W, Sturmer T, Rothenbacher D, Brenner RE: Osteoarthritis-patterns, cardio-metabolic risk factors and risk of all-cause mortality: 20 years follow-up in patients after hip or knee replacement. Scientific Reports 8 (1), 5253, 2018. 

Campa D, Pastore M, Capurso G, Hackert T, Di Leo M, Izbicki JR, Khaw KT, Gioffreda D, Kupcinskas J, Pasquali C, Macinga P, Kaaks R, Stigliano S, Peeters PH, Key TJ, Talar-Wojnarowska R, Vodicka P, Valente R, Vashist YK, Salvia R, Papaconstantinou I, Shimizu Y, Valsuani C, Zambon CF, Gazouli M, Valantiene I, Niesen W, Mohelnikova-Duchonova B, Hara K, Soucek P, Malecka-Panas E, Bueno-De-Mesquita HB, Johnson T, Brenner H, Tavano F, Fogar P, Ito H, Sperti C, Butterbach K, Latiano A, Andriulli A, Cavestro GM, Busch ORC, Dijk F, Greenhalf W, Matsuo K, Lombardo C, Strobel O, König AK, Cuk K, Strothmann H, Katzke V, Cantore M, Mambrini A, Oliverius M, Pezzilli R, Landi S, Canzian F: Do pancreatic cancer and chronic pancreatitis share the same genetic risk factors? A PANcreatic Disease ReseArch (PANDoRA) consortium investigation. International Journal of Cancer 142 (2), 290-296, 2018. 

Chen C, Stock C, Hoffmeister M, Brenner H: Public health impact of colonoscopy use on colorectal cancer mortality in Germany and the United States. Gastrointestinal Endoscopy 87 (1), 213-221, 2018. 

Chen T, Brenner H, Fallah M, Jansen L, Castro FA, Geiss K, Holleczek B, Katalinic A, Luttmann S, Sundquist K, Ressing M, Xu L, Hemminki K, GEKID Cancer Survival Working Group: Response: Methods for second primary cancers evaluation have to be standardized (IJC-17-2354). International Journal of Cancer 142 (6), 1286-1287, 2018. 

Colombo M, Lopez-Perolio I, Meeks HD, Caleca L, Parsons MT, Li H, De Vecchi G, Tudini E, Foglia C, Mondini P, Manoukian S, Behar R, Garcia EBG, Meindl A, Montagna M, Niederacher D, Schmidt AY, Varesco L, Wappenschmidt B, Bolla MK, Dennis J, Michailidou K, Wang Q, Aittomaki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadel A, Benitez J, Boeckx B, Bogdanova NV, Bojesen SE, Bonanni B, Brauch H, Brenner H, Burwinkel B, Chang-Claude J, Conroy DM, Couch FJ, Cox A, Cross SS, Czene K, Devilee P, Dork T, Eriksson M, Fasching PA, Figueroa J, Fletcher O, Flyger H, Gabrielson M, Garcia-Closas M, Giles GG, Gonzalez-Neira A, Guenel P, Haiman CA, Hall P, Hamann U, Hartman M, Hauke J, Hollestelle A, Hopper JL, Jakubowska A, Jung A, Kosma VM, Lambrechts D, Le Marchand L, Lindblom A, Lubinski J, Mannermaa A, Margolin S, Miao H, Milne RL, Neuhausen SL, Nevanlinna H, Olson JE, Peterlongo P, Peto J, Pylkas K, Sawyer EJ, Schmidt MK, Schmutzler RK, Schneeweiss A, Schoemaker MJ, See MH, Southey MC, Swerdlow A, Teo SH, Toland AE, Tomlinson I, Truong T, van Asperen CJ, van den Ouweland AMW, van der Kolk LE, Winqvist R, Yannoukakos D, Zheng W, Dunning AM, Easton DF, Henderson A, Hogervorst FBL, Izatt L, Offitt K, Side LE, van Rensburg EJ, Embrace S, Hebon S, McGuffog L, Antoniou AC, Chenevix-Trench G, Spurdle AB, Goldgar DE, Hoya M, Radice P: The BRCA2 c.68-7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity. Human Mutation 39 (5), 729-741, 2018. 

Dadaev T, Saunders E, Newcombe P, Anokian E, Leongamornlert D, …, Brenner H, …, Haiman C, Eeles R, Conti D, Kote-Jarai Z, Cuk, K, Canzian, F, ....: Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants. Nature Communications 9 (1), 2256, 2018. 

Delphan,M., Lin,T.D., Liesenfeld,D.B., Nattenmuller,J., Bohm,J.T., Gigic,B., Habermann,N., Zielske,L., Schrotz-King,P., Schneider,M., Ulrich,A., Kauczor,H.U., Ulrich,C.M., Ose,J.: Associations of branched-chain amino acids with parameters of energy balance and survival in colorectal cancer patients: results from the ColoCare study. Metabolomics 14 (3), 2018. 

Erben V, Carr PR, Holleczek B, Stegmaier C, Hoffmeister M, Brenner H: Dietary patterns and risk of advanced colorectal neoplasms: a large population based screening study in Germany. Preventive Medicine 111, 101-109, 2018. 

Eyl RE, Koch-Gallenkamp L, Jansen L, Walter V, Carr PR, Hoffmeister M, Chang-Claude J, Brenner H, Arndt V: Potential determinants of physical inactivity among long-term colorectal cancer survivors. Journal of Cancer Survivorship 12 (5), 679-690, 2018. 

Forman D, Bauld L, Bonanni B, Brenner H, Brown K, Dillner J, Kampman E, Manczuk M, Riboli E, Steindorf K, Storm H, Espina C, Wild CP: Time for a European initiative for research to prevent cancer: A manifesto for Cancer Prevention Europe (CPE). Journal of Cancer Policy 17, 15-23, 2018. 

Fullman,N., Yearwood,J., Abay,S.M., Abbafati,C., Abd-Allah,F., Abdela,J., Abdelalim,A., Abebe,Z., Abebo,T.A., ..., Brenner, H, GBD 2016 Healthcare Access and Quality Collaborators (868 Collaborators): Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016. Lancet 391 (10136), 2236-2271, 2018. 

Gao X, Zhang Y, Schöttker B, Brenner H: Vitamin D status and epigenetic-based mortality risk score: strong independent and joint prediction of all-cause mortality in a population-based cohort study. Clinical Epigenetics 10, 2018. 

Gao X, Zhang Y, Mons U, Brenner H: Leukocyte telomere length and epigenetic-based mortality risk score: associations with all-cause mortality among older adults. Epigenetics 13 (8), 846-857, 2018. 

Gào X, Brenner H, Holleczek B, Cuk K, Zhang Y, Anusruti A, Xuan Y, Xu Y, Schöttker B: Urinary 8-isoprostane levels and occurrence of lung, colorectal, prostate, breast and overall cancer: Results from a large, population-based cohort study with 14 years of follow-up. Free Radical Biology and Medicine 123, 20-26, 2018. 

Gies A, Cuk K, Schrotz-King P, Brenner H: Direct comparison of diagnostic performance of 9 quantitative fecal immunochemical tests for colorectal cancer screening. Gastroenterology 154 (1), 93-104, 2018. 

Gies A, Cuk K, Schrotz-King P, Brenner H: Fecal immunochemical test for hemoglobin in combination with fecal transferrin in colorectal cancer screening. United European Gastroenterology Journal 6 (8), 1223-1231, 2018. 

Gies A, Cuk K, Schrotz-King P, Brenner H: Direct comparison of ten quantitative fecal immunochemical tests for hemoglobin stability in colorectal cancer screening. Clinical and Translational Gastroenterology 9 (7), 168, 2018. 

Gigic B, Boeing H, Toth R, Böhm J, Habermann N, Scherer D, Schrotz-King P, Abbenhardt-Martin C, Skender S, Brenner H, Chang-Claude J, Hoffmeister M, Syrjala K, Jacobsen PB, Schneider M, Ulrich A, Ulrich CM: Associations between dietary patterns and longitudinal quality of life changes in colorectal cancer patients: the ColoCare study. Nutrition and Cancer 70 (1), 51-60, 2018. 

Gredner T, Behrens G, Stock C, Brenner H*, Mons U* (*equal contributions): Cancers Due to Infection and Selected Environmental Factors Estimation of the Attributable Cancer Burden in Germany. Deutsches Aerzteblatt International 115 (35-36), 586, 2018. 

Griswold,M.G., Fullman,N., Hawley,C., Arian,N., Zimsen,S.R.M., Tymeson,H.D., Venkateswaran,V., Tapp,A.D., Forouzanfar,M.H., Salama,J.S., Abate,K.H., Abate,D., Abay,S.M., Abbafati,C., Abdulkader,R.S., Abebe,Z., Aboyans,V., Abrar,M.M., Brenner,H, Schöttker, B: Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 392 (10152), 1015-1035, 2018. 

Hajek A, Bock JO, Saum KU, Matschinger H, Brenner H, Holleczek B, Haefeli WE, Heider D, König HH: Frailty and health care costs - longitudinal results of a prospective cohort study. Age and Ageing 47 (2), 233-241, 2018. 

Hajek A, Bock JO, Saum KU, Schöttker B, Brenner H, Heider D, König HH: [Morbidity Differences by Health Insurance Status in Old Age]. Unterschiede in der Morbidität nach Krankenversichertenstatus im Alter. Gesundheitswesen 80 (6), 551-556, 2018. 

Heinrichs SKM, Hess T, Becker J, Hamann L, Vashist YK, Butterbach K, Schmidt T, Alakus H, Krasniuk I, Hoblinger A, Lingohr P, Ludwig M, Hagel AF, Schildberg CW, Veits L, Gyvyte U, Weise K, Schuller V, Bohmer AC, Schroder J, Gehlen J, Kreuser N, Hofer S, Lang H, Lordick F, Malfertheiner P, Moehler M, Pech O, Vassos N, Rodermann E, Izbicki JR, Kruschewski M, Ott K, Schumann RR, Vieth M, Mangold E, Gasenko E, Kupcinskas L, Brenner H, Grimminger P, Bujanda L, Sopena F, Espinel J, Thomson C, Perez-Aisa A, Campo R, Geijo F, Collette D, Bruns C, Messerle K, Gockel I, Nothen MM, Lippert H, Ridwelski K, Lanas A, Keller G, Knapp M, Leja M, Kupcinskas J, Garcia-Gonzalez MA, Venerito M, Schumacher J: Evidence for PTGER4, PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level. Cancer Medicine 7 (10), 5057-5065, 2018. 

Hoppe LK, Muhlack DC, König W, Carr PR, Brenner H, Schöttker B: Association of abnormal serum potassium levels with arrhythmias and cardiovascular mortality: a systematic review and meta-analysis of observational studies. Cardiovascular Drugs and Therapy 32 (2), 197-212, 2018. 

Horne HN, Oh H, Sherman ME, Palakal M, Hewitt SM, …, Brenner H, …, Van Leeuwen FF, Van’t Veer LJ, Garcia-Closas M, Figueroa JD, Cuk, Eilber, Chang-Claude, Saum: E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium. Scientific Reports 8 (1), 6574, 2018. 

Huang L, Jansen L, Balavarca Y, Babaei M, van der Geest L, Lemmens V, Van Eycken L, De Schutter H, Johannesen TB, Primic-Zakelj M, Zadnik V, Besselink MG, Schrotz-King P, Brenner H: Stratified survival of resected and overall pancreatic cancer patients in Europe and the USA in the early twenty-first century: a large, international population-based study. BMC Medicine 16 (1), 125, 2018. 

Huhn S, da Silva Filho MI, Sanmuganantham T, Pichulik T, Catalano C, Pardini B, Naccarati A, Polakova-Vymetálkova V, Jiraskova K, Vodickova L, Vodicka P, Löffler MW, Courth L, Wehkamp J, Din FVN, Timofeeva M, Farrington SM, Jansen L, Hemminki K, Chang-Claude J, Brenner H, Hoffmeister M, Dunlop MG, Weber ANR, Försti A: Coding variants in NOD-like receptors: an association study on risk and survival of colorectal cancer. PLoS ONE 13 (6), e0199350, 2018. 

Jansen H, Jänsch A, Breitling LP, Hoppe L, Dallmeier D, Schmucker R, Brenner H, König W, Rothenbacher D: Hs-cTroponins for the prediction of recurrent cardiovascular events in patients with established CHD - A comparative analysis from the KAROLA study. International Journal of Cardiology 250, 247-252, 2018. 

Jansen L, Buttmann-Schweiger N, Listl S, Ressing M, Holleczek B, Katalinic A, Luttmann S, Kraywinkel K, Brenner H, for the GEKID Cancer Survival Working Group: Differences in incidence and survival of oral cavity and pharyngeal cancers between Germany and the United States depend on the HPV-association of the cancer site. Oral Oncology 76, 8-15, 2018. 

Jeon J, Du M, Schoen RE, Hoffmeister M, Newcomb PA, ..., Chang-Claude J, ..., Brenner H, Hayes RB, White E, Peters U, Hsu L, on behalf of the Colorectal Transdisciplinary (CORECT) Study, Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO): Determining risk of colorectal cancer and starting age of screening based on lifestyle, environmental, and genetic factors. Gastroenterology 154 (8), 2152-2164.e19, 2018. 

Kather JN, Suarez-Carmona M, Charoentong P, Weis CA, Hirsch D, Bankhead P, Horning M, Ferber D, Kel I, Herpel E, Schott S, Zörnig I, Utikal J, Marx A, Gaiser T, Brenner H, Chang-Claude J, Hoffmeister M, Jäger D, Halama N: Topography of cancer-associated immune cells in human solid tumors. elife 7, e36967, 2018. 

Khallouki,F., Ricarte,I., Breuer,A., Owen,R.W.: Characterization of phenolic compounds in mature Moroccan Medjool date palm fruits (Phoenix dactylifera) by HPLC-DAD-ESI-MS. Journal of Food Composition and Analysis 70, 63-71, 2018. 

Kharazmi E, Chen T, Fallah M, Sundquist K, Sundquist J, Albin M, Weiderpass E, Hemminki K: Familial risk of pleural mesothelioma increased drastically in certain occupations: A nationwide prospective cohort study. European Journal of Cancer 103, 1-6, 2018. 

Kharazmi,E., Babaei,M., Fallah,M., Chen,T., Sundquist,K., Hemminki,K.: Importance of tumor location and histology in familial risk of upper gastrointestinal cancers: a nationwide cohort study. Clinical Epidemiology 10, 1169-1179, 2018. 

Klein A, Wolpin B, Risch H, Stolzenberg-Solomon R, Mocci E, …, Brenner H, …, Kaaks R, ..., Chanock S, Obazee O, Petersen G, Amundadottir L, Obazee, O, Petersen GM, Amundadottir LT: Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer. Nature Communications 9 (1), 556, 2018. 

Klett H, Balavarca Y, Toth R, Gigic B, Habermann N, Scherer D, Schrotz-King P, Ulrich A, Schirmacher P, Herpel E, Brenner H, Ulrich C, Michels KB, Busch H, Boerries M: Robust prediction of gene regulation in colorectal cancer tissues from DNA methylation profiles. Epigenetics 13 (4), 386-397, 2018. 

Krilaviciute A, Stock C, Leja M, Brenner H: Potential for non-invasive breath tests for preselecting individuals for invasive gastric cancer screening endoscopy. Journal of Breath Research 12 (3), 036009, 2018. 

Kuhn T, Nonnenmacher T, Sookthai D, Schubel R, Quintana Pacheco DA, von Stackelberg O, Graf ME, Johnson T, Schlett CL, Kirsten R, Ulrich CM, Kaaks R, Kauczor HU, Nattenmuller J: Anthropometric and blood parameters for the prediction of NAFLD among overweight and obese adults. Bmc Gastroenterology 18 (1), 113, 2018. 

Maalmi H, Walter V, Jansen L, Owen RW, Ulrich A, Schöttker B, Chang-Claude J, Hoffmeister M, Brenner H: Dose-response relationship between serum retinol levels and survival in patients with colorectal cancer: results from the DACHS study. Nutrients 10 (4), 510, 2018. [Version-Id: 89822; Published-Id: 87948; Kst: C020, C070, G110]

Maia,I.R.D., Trevisan,M.T.S., Silva,M.G.D., Klika,K.D., de Brito,E., Silva,L.M.A.E., Pinto,F.D.L., Breuer,A., Owen,R.W.: Characterization and Quantitation of Polyphenolic Compounds in Senna splendida from the Northeast of Brazil. Natural Product Communications 13 (6), 707-712, 2018. 

Matejcic M, Saunders E, Dadaev T, Brook M, Wang K, …, Brenner H, …, Eeles R, Kote-Jarai Z, Conti D, Haiman C: Germline variation at 8q24 and prostate cancer risk in men of European ancestry. Nature Communications 9 (1), 4616, 2018. 

Minicozzi P, Walsh PM, Sánchez MJ, Trama A, Innos K, Marcos-Gragera R, Dimitrova N, Botta L, Johannesen TB, Rossi S, Sant M, EUROCARE-5 Working Group (Collaborator from DKFZ: Brenner H): Is low survival for cancer in Eastern Europe due principally to late stage at diagnosis?. European Journal of Cancer 93, 127-137, 2018. 

Mons U*, Gredner T* (*equal contributions), Behrens G, Stock C, Brenner H: Cancers due to smoking and high alcohol consumption. Deutsches Aerzteblatt International 115 (35-36), 571-577, 2018. 

Nabers A, Perna L, Lange J, Mons U, Schartner J, Guldenhaupt J, Saum KU, Janelidze S, Holleczek B, Rujescu D, Hansson O, Gerwert K, Brenner H: Amyloid blood biomarker detects Alzheimer's disease. EMBO Molecular Medicine 10 (5), 2018. 

NCD Risk Factors Collaboration (NCD-RisC)* * Collaborator from DKFZ: Brenner H, Kaaks, R, Saum, U, Schöttker, B: Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants. International Journal of Epidemiology 47 (3), 872, 2018.

Neumeyer S, Banbury BL, Arndt V, Berndt SI, Bezieau S, Bien SA, Buchanan DD, Butterbach K, Caan BJ, Campbell PT, Casey G, Chan AT, Chanock SJ, Dai JY, Gallinger S, Giovannucci EL, Giles GG, Grady WM, Hampe J, Hoffmeister M, Hopper JL, Hsu L, Jenkins MA, Joshi A, Larsson SC, Le Marchand L, Lindblom A, Moreno V, Lemire M, Li L, Lin Y, Offit K, Newcomb PA, Pharaoh PD, Potter JD, Qi L, Rennert G, Schafmayer C, Schoen RE, Slattery ML, Song M, Ulrich CM, Win AK, White E, Wolk A, Woods MO, Wu AH, Gruber SB, Brenner H, Peters U, Chang-Claude J: Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer. British Journal of Cancer 118 (12), 1639-1647, 2018. 

Niedermaier T, Weigl K, Hoffmeister M, Brenner H: Diagnostic Performance of One-off Flexible Sigmoidoscopy with Fecal Immunochemical Testing in a Large Screening Population. Epidemiology 29 (3), 397-406, 2018. 

Niedermaier T, Weigl K, Brenner H: Overcoming misled design and interpretation of randomised trials. European Journal of Epidemiology 33 (8), 775-776, 2018. 

Niedermaier T, Weigl K, Gies A, Hoffmeister M, Brenner H: Accuracy of a fecal immunochemical test according to outside temperature and travel time. Clinical Epidemiology 10, 1203-1213, 2018. 

Niedermaier T, Weigl K, Hoffmeister M, Brenner H: Flexible sigmoidoscopy in colorectal cancer screening: implications of different colonoscopy referral strategies. European Journal of Epidemiology 33 (5), 473-484, 2018. 

O’Mara TA, Glubb DM, Amant F, Annibali D, Ashton K, …, Brenner H, …, Burwinkel, B, Chang-Claude, J, Tomlinson I, Easton DF, Spurdle AB, Thompson DJ: Identification of nine new susceptibility loci for endometrial cancer. Nature Communications 9 (1), 3166, 2018. 

Ordóñez-Mena JM, Walter V, Schöttker B, Jenab M, O’Doherty MG, Kee F, Bueno-de-Mesquita B, Peeters PHM, Stricker BH, Ruiter R, Hofman A, Söderberg S, Jousilahti P, Kuulasmaa K, Freedman ND, Wilsgaard T, Wolk A, Nilsson LM, Tjonneland A, Quirós JR, van Duijnhoven FJB, Siersema PD, Boffetta P, Trichopoulou A, Brenner H, on behalf of the Consortium on Health and Ageing, Network of Cohorts in Europe and the United States (CHANCES): Impact of prediagnostic smoking and smoking cessation on colorectal cancer prognosis: a meta-analysis of individual patient data from cohorts within the CHANCES consortium. Annals of Oncology 29 (2), 472-483, 2018. 

Ose J, Botma A, Balavarca Y, Buck K, Scherer D, Habermann N, Beyerle J, Pfutze K, Seibold P, Kap EJ, Benner A, Jansen L, Butterbach K, Hoffmeister M, Brenner H, Ulrich A, Schneider M, Chang-Claude J, Burwinkel B, Ulrich CM: Pathway analysis of genetic variants in folate-mediated one-carbon metabolism-related genes and survival in a prospectively followed cohort of colorectal cancer patients. Cancer Medicine 7 (7), 2797-2807, 2018. 

Painter JN, O`Mara TA, Morris AP, Cheng THT, Gorman M, Martin L, Hodson S, Jones A, Martin NG, Gordon S, Henders AK, Attia J, McEvoy M, Holliday EG, Scott RJ, Webb PM, Fasching PA, Beckmann MW, Ekici AB, Hein A, Rubner M, Hall P, Czene K, Dork T, Durst M, Hillemanns P, Runnebaum I, Lambrechts D, Amant F, Annibali D, Depreeuw J, Vanderstichele A, Goode EL, Cunningham JM, Dowdy SC, Winham SJ, Trovik J, Hoivik E, Werner HMJ, Krakstad C, Ashton K, Otton G, Proietto T, Tham E, Mints M, Ahmed S, Healey CS, Shah M, Pharoah PDP, Dunning AM, Dennis J, Bolla MK, Michailidou K, Wang Q, Tyrer JP, Hopper JL, Peto J, Swerdlow AJ, Burwinkel B, Brenner H, Meindl A, Brauch H, Lindblom A, Chang-Claude J, Couch FJ, Giles GG, Kristensen VN, Cox A, Zondervan KT, Nyholt DR, MacGregor S, Montgomery GW, Tomlinson I, Easton DF, Thompson DJ, Spurdle AB: Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses. Cancer Medicine 7 (5), 1978-1987, 2018. 

Pulte D, Jansen L, Brenner H: Disparities in Colon Cancer Survival by Insurance Type: A Population-Based Analysis. Diseases of the Colon and Rectum 61 (5), 538-546, 2018. 

Pulte D, Weberpals J, Schröder CC, Emrich K, Holleczek B, Katalinic A, Luttmann S, Sirri E, Jansen L, Brenner H, for the GEKID Cancer Survival Working Group: Survival of patients with hepatobiliary tract and duodenal cancer sites in Germany and the United States in the early 21st century. International Journal of Cancer 143 (2), 324-332, 2018. 

Qian J, Tikk K, Werner S, Balavarca Y, Saadati M, Hechtner M, Brenner H: Biomarker discovery study of inflammatory proteins for colorectal cancer early detection demonstrated importance of screening setting validation. Journal of Clinical Epidemiology 104, 24-34, 2018. 

Rachakonda S, Kong H, Srinivas N, Garcia-Casado Z, Requena C, Fallah M, Heidenreich B, Planelles D, Traves V, Schadendorf D, Nagore E, Kumar R: Telomere length, telomerase reverse transcriptase promoter mutations, and melanoma risk. Genes Chromosomes and Cancer 57 (11), 564-572, 2018. 

Rosch T, Altenhofen L, Kretschmann J, Hagen B, Brenner H, Pox C, Schmiegel W, Theilmeier A, Aschenbeck J, Tannapfel A, von Stillfried D, Zimmermann-Fraedrich K, Wegscheider K: Risk of Malignancy in Adenomas Detected During Screening Colonoscopy. Clinical Gastroenterology and Hepatology 16 (11), 1754-1761, 2018. 

Rudolph A, Song M, Brook MN, Milne RL, Mavaddat N, Michailidou K, Bolla MK, Wang Q, Dennis J, Wilcox AN, Hopper JL, Southey MC, Keeman R, Fasching PA, Beckmann MW, Gago-Dominguez M, Castelao JE, Guenel P, Truong T, Bojesen SE, Flyger H, Brenner H, Arndt V, Brauch H, Bruning T, Mannermaa A, Kosma VM, Lambrechts D, Keupers M, Couch FJ, Vachon C, Giles GG, MacInnis RJ, Figueroa J, Brinton L, Czene K, Brand JS, Gabrielson M, Humphreys K, Cox A, Cross SS, Dunning AM, Orr N, Swerdlow A, Hall P, Pharoah PDP, Schmidt MK, Easton DF, Chatterjee N, Chang-Claude J, Garcia-Closas M: Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium. International Journal of Epidemiology 47 (2), 526-536, 2018. 

Schottker B, Muhlack DC, Hoppe LK, Holleczek B, Brenner H: Updated analysis on polypharmacy and mortality from the ESTHER study. European Journal of Clinical Pharmacology 74 (7), 981-982, 2018. 

Seibert TM, Fan CC, Wang Y, Zuber V, Karunamuni R, Parsons JK, Eeles RA, Easton DF, Kote-Jarai Z, Al Olama AA, Garcia SB, Muir K, Gronberg H, Wiklund F, Aly M, Schleutker J, Sipeky C, Tammela TL, Nordestgaard BG, Nielsen SF, Weischer M, Bisbjerg R, Roder MA, Iversen P, Key TJ, Travis RC, Neal DE, Donovan JL, Hamdy FC, Pharoah P, Pashayan N, Khaw KT, Maier C, Vogel W, Luedeke M, Herkommer K, Kibel AS, Cybulski C, Wokolorczyk D, Kluzniak W, Cannon-Albright L, Brenner H, Cuk K, Saum KU, Park JY, Sellers TA, Slavov C, Kaneva R, Mitev V, Batra J, Clements JA, Spurdle A, Teixeira MR, Paulo P, Maia S, Pandha H, Michael A, Kierzek A, Karow DS, Mills IG, Andreassen OA, Dale AM: Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. BMJ 360, j5757, 2018. 

Shi J, Wu L, Zheng W, Wen W, Wang S, Shu X, Long J, Shen CY, Wu PE, Saloustros E, Chang-Claude J, Brenner H, Shu XO, Cai Q: Genetic evidence for the association between schizophrenia and breast cancer. Journal of Psychiatry and Brain Science 3, 7, 2018. 

Stock C, Mons U, Brenner H: Projection of cancer incidence rates and case numbers until 2030: a probabilistic approach applied to German cancer registry data (1999-2013). Cancer Epidemiology 57, 110-119, 2018. 

Su YR, Di C, Bien S, Huang L, Dong X, Abecasis G, Berndt S, Bezieau S, Brenner H, Caan B, Casey G, Chang-Claude J, Chanock S, Chen S, Connolly C, Curtis K, Figueiredo J, Gala M, Gallinger S, Harrison T, Hoffmeister M, Hopper J, Huyghe JR, Jenkins M, Joshi A, Le Marchand L, Newcomb P, Nickerson D, Potter J, Schoen R, Slattery M, White E, Zanke B, Peters U, Hsu L: A mixed-effects model for powerful association tests in integrative functional genomics. American Journal of Human Genetics 102 (5), 904-919, 2018. 

Tikk K, Weigl K, Hoffmeister M, Igel S, Schwab M, Hampe J, Klug SJ, Mansmann U, Kolligs F, Brenner H: Study protocol of the RaPS study: novel risk adapted prevention strategies for people with a family history of colorectal cancer. BMC Cancer 18 (1), 720, 2018. 

Tikk K, Czock D, Haefeli WE, Kopp-Schneider A, Brenner H: Clinical trial protocol of the ASTER trial: a double-blind, randomized, placebo-controlled phase III trial evaluating the use of acetylsalicylic acid (ASA) for enhanced early detection of colorectal neoplasms. BMC Cancer 18 (1), 914, 2018. 

Trevisan,M.T.S., Ricarte,I., Dos Santos,S.J.M., Almeida,W.P., Ulrich,C.M., Owen,R.W.: Inhibition of angiotensin I converting enzyme by anacardic acids isolated from Cashew nut (Anacardium occidentale Linn.) shell liquid. International Journal of Food Properties 21 (1), 921-929, 2018. 

Vijayakrishnan J, Studd J, Broderick P, Kinnersley B, Holroyd A, Law PJ, Kumar R, Allan JM, Harrison CJ, Moorman AV, Vora A, Roman E, Rachakonda S, Kinsey SE, Sheridan E, Thompson PD, Irving JA, Koehler R, Hoffmann P, Nothen MM, Heilmann-Heimbach S, Jockel KH, Easton DF, Pharaoh PDP, Dunning AM, Peto J, Canzian F, Swerdlow A, Eeles RA, Kote-Jarai Z, Muir K, Pashayan N, Greaves M, Zimmerman M, Bartram CR, Schrappe M, Stanulla M, Hemminki K, Houlston RS, The PRACTICAL consortium, (Collaborator from DKFZ, Brenner H): Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia. Nature Communications 9 (1), 1340, 2018. 

Wang X, Chan AT, Slattery ML, Chang-Claude J, Potter JD, Gallinger S, Caan B, Lampe JW, Newcomb PA, Zubair N, Hsu L, Schoen RE, Hoffmeister M, Brenner H, Le Marchand L, Peters U, White E: Influence of Smoking, Body Mass Index, and Other Factors on the Preventive Effect of Nonsteroidal Anti-Inflammatory Drugs on Colorectal Cancer Risk. Cancer Research 78 (16), 4790-4799, 2018. 

Weberpals J, Jansen L, Silversmit G, Verbeeck J, van der Geest L, Vissers PAJ, Zadnik V, Brenner H: Comparative performance of a modified landmark approach when no time of treatment data are available within oncological databases: exemplary cohort study among resected pancreatic cancer patients. Clinical Epidemiology 10, 1109-1125, 2018. 

Weigl K, Thomsen H, Balavarca Y, Hellwege J, Shrubsole M, Brenner H: Genetic risk score is associated with prevalence of advanced neoplasms in a colorectal cancer screening population. Gastroenterology 155 (1), 88-98, 2018. 

Weigl K, Chang-Claude J, Knebel P, Hsu L, Hoffmeister M, Brenner H: Strongly enhanced colorectal cancer risk stratification by combining family history and genetic risk score. Clinical Epidemiology 10, 143-152, 2018. 

Wu L, Shi W, Long J, Guo X, Michailidou K, Beesley J, Bolla MK, Shu XO, Lu Y, Cai Q, Al-Ejeh F, Rozali E, Wang Q, Dennis J, Li B, Zeng C, Feng H, Gusev A, Barfield RT, Andrulis IL, Anton-Culver H, Arndt V, Aronson KJ, Auer PL, Barrdahl M, Baynes C, Beckmann MW, Benitez J, Bermisheva M, Blomqvist C, Bogdanova NV, Bojesen SE, Brauch H, Brenner H, Brinton L, Broberg P, Brucker SY, Burwinkel B, Caldes T, Canzian F, Carter BD, Castelao JE, Chang-Claude J, Chen X, Cheng TD, Christiansen H, Clarke CL, Collee M, Cornelissen S, Couch FJ, Cox D, Cox A, Cross SS, Cunningham JM, Czene K, Daly MB, Devilee P, Doheny KF, Dork T, Dos-Santos-Silva I, Dumont M, Dwek M, Eccles DM, Eilber U, Eliassen AH, Engel C, Eriksson M, Fachal L, Fasching PA, Figueroa J, Flesch-Janys D, Fletcher O, Flyger H, Fritschi L, Gabrielson M, Gago-Dominguez M, Gapstur SM, Garcia-Closas M, Gaudet MM, Ghoussaini M, Giles GG, Goldberg MS, Goldgar DE, Gonzalez-Neira A, Guenel P, Hahnen E, Haiman CA, Hakansson N, Hall P, Hallberg E, Hamann U, Harrington P, Hein A, Hicks B, Hillemanns P, Hollestelle A, Hoover RN, Hopper JL, Huang G, Humphreys K, Hunter DJ, Jakubowska A, Janni W, John EM, Johnson N, Jones K, Jones ME, Jung A, Kaaks R, Kerin MJ, Khusnutdinova E, Kosma VM, Kristensen VN, Lambrechts D, Le Marchand L, Li J, Lindstrom S, Lissowska J, Lo WY, Loibl S, Lubinski J, Luccarini C, Lux MP, MacInnis RJ, Maishman T, Kostovska IM, Mannermaa A, Manson JE, Margolin S, Mavroudis D, Meijers-Heijboer H, Meindl A, Menon U, Meyer J, Mulligan AM, Neuhausen SL, Nevanlinna H, Neven P, Nielsen SF, Nordestgaard BG, Olopade OI, Olson JE, Olsson H, Peterlongo P, Peto J, Plaseska-Karanfilska D, Prentice R, Presneau N, Pylkas K, Rack B, Radice P, Rahman N, Rennert G, Rennert HS, Rhenius V, Romero A, Romm J, Rudolph A, Saloustros E, Sandler DP, Sawyer EJ, Schmidt MK, Schmutzler RK, Schneeweiss A, Scott RJ, Scott CG, Seal S, Shah M, Shrubsole MJ, Smeets A, Southey MC, Spinelli JJ, Stone J, Surowy H, Swerdlow AJ, Tamimi RM, Tapper W, Taylor JA, Terry MB, Tessier DC, Thomas A, Thone K, Tollenaar RAEM, Torres D, Truong T, Untch M, Vachon C, Van Den Berg D, Vincent D, Waisfisz Q, Weinberg CR, Wendt C, Whittemore AS, Wildiers H, Willett WC, Winqvist R, Wolk A, Xia L, Yang XR, Ziogas A, Ziv E, Dunning AM, Pharoah PDP, Simard J, Milne RL, Edwards SL, Kraft P, Easton DF, Chenevix-Trench G, Zheng W: A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. Nature Genetics 50 (7), 968, 2018. 

Zhang Y, Saum KU, Schöttker B, Holleczek B, Brenner H: Methylomic survival predictors, frailty, and mortality. Aging 10 (3), 339-357, 2018. 

Krilaviciute A, Leja M, Kopp-Schneider A, Barash O, Khatib S, Amal H, Broza YY, Polaka I, Parshutin S, Rudule A, Haick H, Brenner H: Associations of diet and lifestyle factors with common volatile organic compounds in exhaled breath of average-risk individuals. Journal of Breath Research. Online 26 November 2018.  DOI: 10.1088/1752-7163/aaf3dc

Boakye D, Rillmann B, Walter V, Jansen L, Hoffmeister M, Brenner H: Impact of comorbidity and frailty on prognosis in colorectal cancer patients: a systematic review and meta-analysis. Cancer Treatment Reviews 64, 30-39, 2018. 

Brenner H, Chen C: The colorectal cancer epidemic: challenges and opportunities for primary, secondary and tertiary prevention. British Journal of Cancer 119 (7), 785-792, 2018. 

Carr PR, Alwers E, Bienert S, Weberpals J, Kloor M, Brenner H, Hoffmeister M: Lifestyle factors and risk of sporadic colorectal cancer by microsatellite instability status: a systematic review and meta-analyses. Annals of Oncology 29 (4), 825-834, 2018. 

Erben V, Bhardwaj M, Schrotz-King P, Brenner H: Metabolomics biomarkers for detection of colorectal neoplasms: A systematic review. Cancers 10 (8), 246, 2018. 

Eyl RE, Xie K, Koch-Gallenkamp L, Brenner H, Arndt V: Quality of life and physical activity in long-term (more than 5 years post-diagnosis) colorectal cancer survivors - systematic review. Health and Quality of Life Outcomes 16, 112, 2018. 

Gies A, Bhardwaj M, Stock C, Schrotz-King P, Brenner H: Quantitative fecal immunochemical tests for colorectal cancer screening. International Journal of Cancer 143 (2), 234-244, 2018. 

Maalmi H, Walter V, Jansen L, Boakye D, Schöttker B, Hoffmeister M, Brenner H: Association between blood 25-hydroxyvitamin D levels and survival in colorectal cancer patients: an updated systematic review and meta-analysis. Nutrients 10, E896, 2018. 

Niedermaier,T., Weigl,K., Hoffmeister,M., Brenner,H.: Fecal immunochemical tests in combination with blood tests for colorectal cancer and advanced adenoma detection-systematic review. United European Gastroenterology Journal 6 (1), 13-21, 2018. 

Stocker H, Möllers T, Perna L, Brenner H: The genetic risk of Alzheimers disease beyond APOE e4: A systematic review of Alzheimers genetic risk scores. Translational Psychiatry 8 (1), 166, 2018. 

Yu H, Guan Z, Cuk K, Brenner H, Zhang Y: Circulating MicroRNA biomarkers for lung cancer detection in Western populations. Cancer Medicine 7 (10), 4849-4862, 2018. 

Alwers E, Jia M, Kloor M, Bläker H, Brenner H, Hoffmeister M: Associations between molecular classifications of colorectal cancer and patient survival: a systematic review. Clinical Gastroenterology and Hepatology, 2018. 

Amitay E, Cuk K, Niedermaier T, Weigl K, Brenner H: Factors associated with false positive fecal immunochemical tests in a large German Colorectal Cancer Screening Study. International Journal of Cancer, 2018. 

Amitay EL, Carr PR, Jansen L, Walter V, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M: Association of aspirin and non-steroidal anti-inflammatory drugs and colorectal cancer risk by molecular subtypes. Journal of the National Cancer Institute, 2018. 

Amitay EL, Krilaviciute A, Brenner H: Systematic review: Gut microbiota in fecal samples and detection of colorectal neoplasms. Gut Microbes, 2018. 

Bläker H, Alwers E, Arnold A, Herpel E, Tagscherer KE, Roth W, Jansen L, Walter V, Kloor M, Chang-Claude J, Brenner H, Hoffmeister M: The association between mutations in BRAF and colorectal cancer-specific survival depends on microsatellite status and tumor stage. Clinical Gastroenterology and Hepatology, 2018. 

Brenner H, Gies A: Immunologische Stuhlbluttests - welche Verbesserungen gegenüber dem Guajak basierten Test?. DER Gastroenterologe, 2018. 

Brück K, Jager KJ, Zoccali C, Bello A, Minutolo R, …, Brenner H, …, De Nicola L, Heinze G, Van Biesen W, Stel VS on behalf of the European CKD Burden Consortium: Progression and mortality in patients with CKD attending outpatient nephrology clinics across Europe: A novel analytic approach. Kidney International, 2018. 

Brunssen A, Jansen L, Eisemann N, Waldmann A, Weberpals J, Kraywinkel K, Eberle A, Holleczek B, Zeissig SR, Brenner H, Katalinic A, for the GEKID Cancer Survival Working Group: Long-term relative survival from melanoma in Germany 1997-2013. Melanoma Research, 2018. 

Brunssen A, Jansen L, Eisemann N, Waldmann A, Weberpals J, Kraywinkel K, Eberle A, Holleczek B, Zeissig SR, Brenner H, Katalinic K, GEKID Cancer Survival Working Group: A population-based registry study on relative survival from melanoma in Germany stratified by tumor thickness for each histological subtype. Journal of the American Academy of Dermatology, 2018. 

Carr PR, Weigl K, Jansen L, Walter V, Erben V, Chang-Claude J, Brenner H, Hoffmeister M: Healthy lifestyle factors associated with lower risk of colorectal cancer irrespective of genetic risk. Gastroenterology, 2018. 

Chen C, Stock C, Hoffmeister M, Brenner H: How long does it take until the effects of endoscopic screening on colorectal cancer mortality are fully disclosed? : A Markov model study. International Journal of Cancer, 2018. 

Dai JY, Peters U, Wang X, Chang-Claude J, Slattery ML, Chan A, Lemire M, Berndt SI, Casey G, Song M, Jenkins MA, Newcomb PA, Brenner H, Thrift A, White E, Hsu L: Diagnostics of pleiotropy in Mendelian randomization studies: Global and individual tests for direct effects. American Journal of Epidemiology, 2018. 

Doege D, Thong MSY, Koch-Gallenkamp L, Bertram H, Eberle A, Holleczek B, Waldeyer-Sauerland M, Waldmann A, Zeissig SR, Brenner H, Arndt V: The role of psychosocial resources for long-term breast, colorectal and prostate cancer survivors: Prevalence and associations with health-related quality of life. Supportive Care in Cancer, 2018. 

Eddouks M, Khallouki F, Owen RW, Hebi M, Burcelin R: Evaluation of glucose and lipid lowering activity of Arganimide A in normal and streptozotocin-induced diabetic rats. Endocrine, metabolic and immune disorders drug targets, 2018. 

Finke I, Behrens G, Weißer L, Brenner H, Jansen L: Socioeconomic differences and lung cancer survival - systematic review and meta-analysis. Frontiers in Oncology, 2018. 

GBD 2017 population and fertility collaborators (Collaborator from DKFZ: Brenner H): Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease 2017. Lancet, 2018. 

Global Burden of Disease Cancer Collaboration, Fitzmaurice C, Akinyemiju TF, Al Lami FH, Alam T, …, Brenner H, …, Yonemoto N, Younis MZ, Murray CJL, Naghavi M: Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2016: a systematic analysis for the Global Burden of Disease Study. JAMA Oncology, 2018. 

Himbert C, Ose J, Nattenmuller J, Warby CA, Holowatyj AN, Bohm J, Lin T, Haffa M, Gigic B, Hardikar S, Scherer D, Zielske L, Schrotz-King P, Koelsch T, Siegel EM, Shibata D, Ulrich A, Schneider M, Hursting SD, Kauczor HU, Ulrich CM: Body fatness, adipose tissue compartments and biomarkers of inflammation and angiogenesis in colorectal cancer: the ColoCare Study. Cancer Epidemiology Biomarkers and Prevention, 2018. 

Hoffmeister M, Holleczek B, Stock C, Zwink N, Stolz T, Stegmaier C, Brenner H: Utilization and determinants of follow-up colonoscopies within 6 years after screening colonoscopy: prospective cohort study. International Journal of Cancer, 2018. 

Huang L, Jansen L, Balavarca Y, van der Geest L, Lemmens V, van Eycken L, De Schutter H, Johannesen TB, Primic-Zakelj M, Zadnik V, Mägi M, Pulte D, Schrotz-King P, Brenner H: Non-surgical therapies for resected and unresected pancreatic cancer in Europe and USA in 2003-2014: a large international population-based study. International Journal of Cancer, 2018. 

Lin HY, Huang PY, Chen DT, Sellers TA, Pow-Sang J, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Hamdy F, Neal DE, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau SN, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Kaneva R, Batra J, Teixeira MR, Pandha H, Lu YJ, the PRACTICAL consortium, Park JY: AA9int: SNP interaction pattern search using non-hierarchical additive model set. Bioinformatics, 2018. 

Logan C, Weiss J, König W, Stahl B, Carr P, Brenner H, Rothenbacher D, Genuneit J: sCD14 concentration in human breast milk and its potential role in child atopic dermatitis: Results of the Ulm Birth Cohort Studies. Clinical and Experimental Allergy, 2018. 

Möllers T, Stocker H, Wei W, Perna L, Brenner H: Length of hospital stay and dementia: a systematic review of observational studies. International Journal of Geriatric Psychiatry, 2018. 

Muhlack DC, Hoppe LK, Stock C, Haefeli WE, Brenner H, Schöttker B: The associations of geriatric syndromes and other patient characteristics with the current and future use of potentially inappropriate medications in a large cohort study. European Journal of Clinical Pharmacology, 2018. 

Nabers A, Perna L, Lange J, Mons U, Schartner J, Güldenhaupt J, Saum KU, Janelidze S, Holleczek B, Rujescu D, Hansson O, Gerwert K, Brenner H: Amyloid blood biomarker detects alzheimers disease. EMBO Molecular Medicine, 2018. 

Neumeyer S, Banbury BL, Arndt V, Berndt SI, Bezieau S, Bien SA, Buchanan DD, Butterbach K, Caan BJ, Campbell PT, Casey G, Chan AT, Chanock SJ, Dai JY, Gallinger S, Giovannucci EL, Giles GG, Grady WM, Hampe J, Hoffmeister M, Hopper JL, Hsu L, Jenkins MA, Joshi A, Larsson SC, Le Marchand L, Lindblom A, Moreno V, Lemire M, Li L, Lin Y, Offit K, Newcomb PA, Pharaoh PD, Potter JD, Qi L, Rennert G, Schafmayer C, Schoen RE, Slattery ML, Song M, Ulrich CM, Win AK, White E, Wolk A, Woods MO, Wu AH, Gruber SB, Brenner H, Peters U, Chang-Claude J: Mendelian randomization study of age at menarche and age at menopause and the risk of colorectal cancer. British Journal of Cancer, 2018. 

Parmar P, Lowry E, Cugliari G, Suderman M, Wilson R, …, Brenner H, Verweij N, Li S, Jarvelin MR, Sebert S, on behalf of the GLOBAL Meth QTL consortium: A meta-analysis of maternal smoking GFI1-CpGs and cardio-metabolic phenotypes in adults. eBioMedicine, 2018. 

Parmar P, Lowry E, Cugliari G, Sudermann M, Wilson R, …, Brenner H, Verweij N, Li S, Chambers JC, Järvelin MR, Sebert S, for the GLOBAL Meth QTL consortium: Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults. eBioMedicine, 2018. 

Peng L, Weigl K, Boakye D, Brenner H: Risk scores for predicting advanced colorectal neoplasia in the average-risk population: A systematic review and meta-analysis. American Journal of Gastroenterology, 2018. 

Qian J, Tikk K, Weigl K, Balavarca Y, Brenner H: Fibroblast growth factor 21 as a circulating biomarker at various stages of colorectal carcinogenesis. British Journal of Cancer, 2018. 

Raina P, Gilsing A, Freisling H, van den Heuvel E, Sohel N, Jenab M, Ferrari P, Tjonneland A, Benetou V, Picavet S, Eriksson S, Schöttker B, Brenner H, Saum KU, Perna L, Wilsgaard T, Trichopoulou A, Boffetta P, Griffith L: The combined effect of cancer and cardio-metabolic conditions on the mortality burden in older adults. Journals of Gerontology / A, Biological Sciences and Medical Sciences, 2018. 

Schmit SL, Edlund CK, Schumacher FR, Gong J, Harrison TA, …, Arndt V, …, Brenner H, …, Butterbach K, ..., Chang-Claude J, ..., Hoffmeister M, ..., Casey G, Hsu L, Conti DV, Gruber SB.: Novel common genetic susceptibility loci for colorectal cancer. Journal of the National Cancer Institute, 2018. 

Schöttker B, Hagen L, Zhang Y, Gào X, Holleczek B, Gao X, Brenner H: Serum 25-hydroxyvitamin D levels as an ageing marker. Strong associations with age and all-cause mortality independent from telomere length, epigenetic age acceleration and 8-isoprostane levels. Journal of Gerontology, 2018. 

Schumacher J, Heinrichs SKM, Hess T, Becker J, Hamann L, Vashist YK, Butterbach K, Schmidt T, Alakus H, Krasniuk I, Höblinger A, Lingohr P, Ludwig M, Hagel AF, Schildberg CW, Veits L, Gyvyte U, Schüller V, Böhmer A, Schröder J, Gehlen J, Kreuser N, Lang H, Lordick F, Malfertheiner P, Moehler M, Pech O, Vassos N, Rodermann E, Izbicki JR, Kruschewski M, Ott K, Schumann RR, Vieth M, Mangold E, Gasenko E, Kupcinskas L, Brenner H, Grimminger P, Bujanda L, Sopena F, Espinel J, Thomson C, Perez-Aisa A, Campo R, Geijo F, Collette D, Bruns C, Gockel I, Nöthen MM, Lippert H, Ridwelski K, Lanas A, Keller G, Knapp M, Leja M, Kupcinskas J, Garcia-Gonzalez MA, Venerito M: Evidence for PTGER4, PSCA and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level. Cancer Medicine, 2018. 

Shu X, Wu L, Khankari NK, Shu XO, Wand TJ, Michailidou K, Bolla MK, Wang Q, Dennis J, Milne RL, Schmidt MK, Pharoah PDP, Andrulis IL, Hunter DJ, Simard J, Easton DF, Zheng W, Breast Cancer Association Consortium (Collaborator from DKFZ: Brenner H): Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis. International Journal of Epidemiology, 2018. 

Thong MSY, Wolschon EM, Koch-Gallenkamp L, Waldmann A, Waldeyer-Sauerland M, Pritzkuleit R, Bertram H, Kajüter H, Eberle A, Holleczek B, Zeissig SR, Brenner H, Arndt V: Still a cancer patient - Associations of cancer identity with patient-reported outcomes and health care use among cancer survivors.  JNCI Cancer Spectrum, 2018.

Vaccaro CA, Lopez-Kostner F, Valle AD, Palmero EI, Rossi BM, Antelo M, Solano A, Carraro DM, Forones NM, Bohorquez M, Lino-Silva LS, Buleje J, Spirandelli F, Abe-Sandes K, Nascimento I, Sullcahuaman Y, Sarroca C, Gonzalez ML, Herrando AI, Alvarez K, Neffa F, Campos Reis Galvao H, Esperon P, Golubicki M, Cisterna D, Cardoso FC, Torrezan GT, Junior SA, Pimenta CAM, da Cruz Formiga MN, Santos E, Sa CU, Oliveira EP, Fujita R, Spirandelli E, Jimenez G, Guindalini RSC, de Azevedo RGMV, Bueno LSM, Dos Santos Nogueira ST, Loarte MT, Padron J, Del Carmen Castro-Mujica M, Del Monte JS, Caballero C, Pena CMM, Pinto J, Barletta-Carrillo C, Angulo MG, Pinero T, Beltran PM, Ashton-Prolla P, Rodriguez Y, Quispe R, Rossi NT, Martin C, Chialina S, Kalfayan PG, Bazo-Alvarez JC, Canete AR, Dominguez-Barrera C, Nunez L, Da Silva SD, Balavarca Y, Wernhoff P, Plazzer JP, Moller P, Hovig E, Dominguez-Valentin M: From colorectal cancer pattern to the characterization of individuals at risk: picture for genetic research in Latin America. International Journal of Cancer, 2018. 

Wang X, Dai JY, Albanes D, Arndt V, Berndt SI, …, Brenner H, …, Wu AH, Gruber SB, Peters U, White E: Mendelian randomization analysis of C-reactive protein on colorectal cancer risk. International Journal of Cancer, 2018. 

Weberpals J, Jansen L, Müller OJ, Brenner H: Long term heart-specific mortality among 347,476 breast cancer patients treated with radiotherapy or chemotherapy: A registry-based cohort study. European Heart Journal, 2018. 

Weigl K, Tikk K, Hoffmeister M, De Toni EN, Hampe J, Kolligs F, Klug SJ, Mansmann U, Nasseh D, Radlovic J, Schwab M, Schweigler D, Stephan A, Brenner H: Feasibility, time-effectiveness, response rates and response patterns of a web-based epidemiological survey among 160 000 adults aged 40-54 years in Germany. Journal of Clinical Epidemiology, 2018. 

Wild B, Herzog W, Schellberg D, Böhlen F, Brenner H, Saum KU, Maatouk I: A short intervention targeting psychosomatic care in older adults with complex health care needs - results of a randomized controlled trial. International Journal of Geriatric Psychiatry, 2018. 

Wu L, Shi W, Long J, Guo X, Michailidou K, ..., Arndt V, …, Brenner H, …, Kraft P, Easton DF, Chenevix-Trench G, Zheng W: Identification of novel susceptibility loci and genes for breast cancer risk: a transcriptome-wide association study of 229,000 women of European descent. Nature Genetics, 2018. 

Xuan Y, Bobak M, Anusruti A, Jansen EHJM, Pajak A, Tamosiunas A, Saum KU, Holleczek B, Gao X, Brenner H, Schottker B: Association of serum markers of oxidative stress with myocardial infarction and stroke: pooled results from four large European cohort studies. European Journal of Epidemiology, 2018. 

Xuan Y, Gào X, Holleczek B, Brenner H, Schöttker B: Prediction of myocardial infarction, stroke and cardiovascular mortality with urinary biomarkers of oxidative stress: Results from a large cohort study. International Journal of Cardiology, 2018. 

Zimmermann-Fraedrich K, Rosch T, Altenhofen L, Kretschmann J, Brenner H, Pox C, Schmiegel W, Theilmeier A, Aschenbeck J, Tannapfel A, von Stillfried D, Wegscheider K: Risk of malignancy in adenomas detected during screening colonoscopy. Clinical Gastroenterology and Hepatology, 2018. 

Erben V, Carr PR, Holleczek B, Stegmaier C, Hoffmeister M, Brenner H: Strong associations of a healthy lifestyle with all stages of colorectal carcinogenesis: results from a large cohort of participants of screening colonoscopy.

Amitay EL, Brenner H: Response to comments on Fusobacterium and colorectal cancer: causal factor or passenger? Results from a large colorectal cancer screening study. Carcinogenesis 39 (1), 85-85, 2018. 

Behrens G*, Gredner T* (*equal contributions), Stock C, Brenner H**, Mons U** (equal contributions): Cancers due to excess weight, low physical activity, and unhealthy diet. Deutsches Aerzteblatt International 115 (35-36), 578-585, 2018. 

Brenner DR, Fehringer G, Zhang ZF, Lee YA, Meyers T, Matsuo K, Ito H, Vineis P, Stucker I, Boffetta P, Brennan P, Christiani DC, Diao N, Hong YC, Landi MT, Morgenstern H, Schwartz AG, Rennert G, Saliba W, McLaughlin JR, Harris CC, Orlow I, Barros Dios JM, Ruano Ravina A, Siemiatycki J, Koushik A, Cote M, Lazarus P, Fernandez-Tardon G, Tardon A, Le Marchand L, Brenner H, Saum KU, Duell EJ, Andrew AS, Consonni D, Olsson A, Hung RJ, Straif K: Alcohol consumption and lung cancer risk: A pooled analysis from the International Lung Cancer Consortium and the SYNERGY study. Cancer Epidemiology 58, 25-32, 2018. 

Gigic B, Boeing H, Toth R, Böhm J, Habermann N, Scherer D, Schrotz-King P, Abbenhardt-Martin C, Skender S, Brenner H, Chang-Claude J, Hoffmeister M, Syrjala K, Jacobsen PB, Schneider M, Ulrich A, Ulrich CM: Associations between dietary patterns and longitudinal quality of life changes in colorectal cancer patients: the ColoCare study. Nutrition and Cancer 70 (1), 51-60, 2018. 

Wang X, Dai JY, Albanes D, Arndt V, Berndt SI, …, Brenner H, …, Wu AH, Gruber SB, Peters U, White E: Mendelian randomization analysis of C-reactive protein on colorectal cancer risk. International Journal of Cancer, 2018. 

Weigl K, Tikk K, Hoffmeister M, De Toni EN, Hampe J, Kolligs F, Klug SJ, Mansmann U, Nasseh D, Radlovic J, Schwab M, Schweigler D, Stephan A, Brenner H: A web-based survey among adults aged 40-54 years was time-effective and yielded stable response patterns. Journal of Clinical Epidemiology, 2018.

Cheriyamundath S, Raghavan R, Vinod D, Megha K, Banerji A, Karel K, Owen RW, Madassery J: Cytotoxic effect of (Z) ethylidene-4,6-dimethoxycoumaran-3-one isolated from Pogostemon quadrifolius (Benth.) on PC-3 and DU-145 prostate cancer cells. Proceedings of the National Academy of Sciences, India Section B, Biological Sciences , 2017.

Khallouki  F, Voggel J, Breuer A, Klika KD, Ulrich CM, Owen RW: Comparison of the major polyphenols in mature Argan fruits from two regions of Morocco. Food Chemistry 221, 1034-1040, 2017.

Khallouki F, Breuer A, Merieme E, Ulrich CM, Owen RW: Characterization and quantitation of the polyphenolic compounds detected in methanol extracts of Pistacia atlantica Desf. fruits from the Guelmim region of Morocco. Journal of Pharmaceutical and Biomedical Analysis 134, 310-318, 2017.

Khallouki F, Eddouks M, Mourad A, Breuer A, Owen RW: Ethnobotanic, ethnopharmacologic aspects and new phytochemical insights into Moroccan Argan fruits. International Journal of Molecular Sciences (18), 11-11, 2017.

Khallouki F, Owen RW, Silvente-Poirot S, Hajji H, Poirot M: Phytochemicals, polyphenols, and non-phenolic compounds and cancer. In. Bioactive Compounds and Cancer. Functional Food for the Prevention and Management of Cancer (First Edition), 278-319, 2017.

Marques S, Trevisan M, De V Silva, M, Owen RW, Breuer A: New methodology for rapid formation/combat of advanced glycation end products (ages) coupled with the hypoxanthine/xanthinenoxidase assay system in the 46th World Chemistry Congress. International Union of pure an applied chemistry (IUPAC 49th General Assembly he), July 7th to 14th, 2017.

Ricarte De O Maia I, Trevisan M, De V Silva M, Breuer A, Owen RW: Content of total phenolic compounds, flavonoids and tannins in methanol extracts of the genus Senna Mill. from the northeast of Brazil and evaluation of antioxidant capacity. Journal of Pharmacognosy an Phytochemistry 6 (5), 1321-1332, 2017.

Trevisan M, de Almeida R, Breuer A, Owen R: Phytochemicals from coffee (Coffea arabica) leaves from three regions of Brazil. Fourth International Congress on Cocoa, Coffee and Tea (Turin, Italy, 25-28 June 2017), 2017.

Trevisan M, Calatayud P, Breuer A, Picó Y, Owen RW: Foodomics reveals the clean-up efficiency of several d-spe in quechers for coffee leaves to determine pesticides in the 46th World Chemistry Congress. International Union of pure an applied chemistry July 7th to 14th, 2017.

Trevisan MTS, Owen RW, Calatayud-Vernich P, Breuer A, Pico Y: Pesticide analysis in coffee leaves using a quick, easy, cheap, effective, rugged and safe approach and liquid chromatography tandem mass spectrometry: Optimization of the clean-up step. Journal of Chromatography / A 1512, 98-106, 2017.

Amitay EL, Werner S, Vital M, Pieper DH, Höfler D, Gierse I-J, Butt J, Balavarca Y, Cuk K, Brenner H: Fusobacterium and colorectal cancer: Causal factor or passenger? Results from a large colorectal cancer screening study. Carcinogenesis 38 (8), 781-788, 2017.

Arndt V, Koch-Gallenkamp L, Jansen L, Bertram H, Eberle A, Holleczek B, Schmid-Höpfner S, Waldmann A, Zeissig SR, Brenner H: Quality of life in long-term and very long-term cancer survivors versus population controls in Germany. Acta Oncologica 56 (2), 190-197, 2017.

Arnold A, Kloor M, Jansen L, Chang-Claude J, Brenner H, von Winterfeld M, Hoffmeister M, Bläker H: The association between microsatellite instability and lymph node count in colorectal cancer. Virchows Archiv 471 (1), 57-64, 2017.

Bamia C, Orfanos P, Juerges H, Schöttker B, Brenner H, Lorbeer R, Aadahl M, Matthews CE, Klinaki E, Katsoulis M, Lagiou P, Bueno-de-Mesquita HB, Eriksson S, Mons U, Saum KU, Kubinova R, Pajak A, Tamosiunas A, Malyutina S, Gardiner J, Peasey A, CPGM de Groot L, Wilsgaard T, Boffetta P, Trichopoulou A, Trichopoulos D: Self-rated health and all-cause and cause-specific mortality of older adults. Individual data meta-analysis of prospective cohort studies participating in the CHANCES Consortium. Maturitas 103, 37-44, 2017.

Barrdahl,M., Rudolph,A., Hopper,J.L., Southey,M.C., Broeks,A., Fasching,P.A., Beckmann,M.W., Gago-Dominguez,M., Castelao,J.E., Guénel,P., Truong,T., Bojesen,S.E., Gapstur,S.M., Gaudet,M.M., Brenner,H., Arndt,V., Brauch,H., Hamann,U., Mannermaa,A., Lambrechts,D., Jongen,L., Flesch-Janys,D., Thoene,K., Couch,F.J., Giles,G.G., Simard,J., Goldberg,M.S., Figueroa,J., Michailidou,K., Bolla,M.K., Dennis,J., Wang,Q., Eilber,U., Behrens,S., Czene,K., Hall,P., Cox,A., Cross,S., Swerdlow,A., Schoemaker,M.J., Dunning,A.M., Kaaks,R., Pharoah,P.D.P., Schmidt,M., Garcia-Closas,M., Easton,D.F., Milne,R.L., Chang-Claude,J.: Gene-environment interactions involving functional variants: Results from the Breast Cancer Association Consortium. International Journal of Cancer 141 (9), 1830-1840, 2017.

Barrow TM, Klett H, Toth R, Böhm J, Gigic B, Habermann N, Scherer D, Schrotz-King P, Skender S, Abbenhardt-Martin C, Zielske L, Schneider M, Ulrich A, Schirmacher P, Herpel E, Brenner H, Busch H, Boerries M, Ulrich CM, Michels KB: Smoking is associated with hypermethylation of the APC 1A promoter in colorectal cancer: the ColoCare Study. Journal of Pathology 243 (3), 366-375, 2017.

Ben Khedher S, Neri M, Papadopoulos A, Christiani DC, Diao N, Harris CC, Olivo-Marston S, Schwartz AG, Cote M, Koushik A, Siemiatycki J, Landi MT, Hung RJ, McLaughlin J, Duell EJ, Andrew AS, Orlow I, Park BJ, Brenner H, Saum KU, Pesatori AC, Stucker I: Menstrual and reproductive factors and lung cancer risk: A pooled analysis from the international lung cancer consortium. International Journal of Cancer 141 (2), 309-323, 2017.

Berendsen A, Kang J, van de Rest O, Jankovic N, Kampman E, Kiefte-deJong J, Franco O, Ikram A, Pikhart H, Nilsson L, Brenner H, Boffetta P, Rafnsson S, Gustafson D, Kyrozis A, Trichopoulou A, Feskens E, Grodstein F, de Groot L: Association of adherence to a healthy diet with cognitive decline in European and American older adults: a meta-analysis within the CHANCES consortium. Dementia and Geriatric Cognitive Disorders 43 (3-4), 215-227, 2017.

Bien SA, Auer PL, Harrison TA, Qu C, Conolly CM, Greenside PG, Chen S, Berndt SI, Bézieau S, Kang HM, Huyghe J, Brenner H, Casey G, Chan AT, Hopper JL, Banbury BL, Chang-Claude J, Chanock SJ, Haile RW, Hoffmeister M, Fuchsberger C, Jenkins MA, Leal SM, Lemire M, Newcomb PA, Gallinger S, Potter JD, Schoen RE, Slattery ML, Smith JD, Le Marchand L, White E, Zanke BW, Abecasis GR, Carlson CS, Peters U, Nickerson DA, Kundaje A, Hsu L, on behalf of GECCO and CCFR: Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data. PLoS ONE 12, e0186518, 2017.

Bock JO, Hajek A, Brenner H, Saum KU, Matschinger H, Haefeli WE, Schoettker B, Quinzler R, Heider D, Koenig HH: A Longitudinal Investigation of Willingness to Pay for Health Insurance in Germany. Health Services Research 52 (3), 1099-1117, 2017.

Boehlen FH, Herzog W, Schellberg D, Maatouk I, Saum KU, Brenner H, Wild B: Self-perceived coping resources of middle-aged and older adults -results of a large population-based study. Aging and Mental Health 21 (12), 1303-1309, 2017.

Boehm J, Pianka F, Stuttgen N, Rho J, Gigic B, Zhang Y, Habermann N, Schrotz-King P, Abbenhardt-Martin C, Zielske L, Lampe PD, Ulrich A, Diener MK, Ulrich CM: Discovery of novel plasma proteins as biomarkers for the development of incisional hernias after midline incision in patients with colorectal cancer: The ColoCare study. Surgery 161 (3), 808-817, 2017.

Bonaventure A, Harewood R, Stiller CA, Gatta G, Clavel J, Stefan DC, Carreira H, Spika D, Marcos-Gragera R, Peris-Bonet R, Pineros M, Sant M, Kuehni CE, Murphy MFG, Coleman MP, Allemani C, CONCORD Working Group*, *Collaborators from DKFZ: Brenner H: Worldwide comparison of survival from childhood leukaemia for 1995-2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual data for 89 828 children from 198 registries in 53 countries. Lancet Hematology 4 (5), e202-e217, 2017.

Breitling LP, Mons U, Hahmann H, Koenig W, Rothenbacher D, Brenner H: The longer, the better? An empirical study of the extent and mechanisms of attenuating biomarker associations in cardiovascular patient cohorts. Clinical Chemistry 63 (3), 673-682, 2017.

Breitling LP, Mons U, Hahmann H, König W, Rothenbacher D, Brenner H: Composite End Points: Implications of changing compositions with longer follow-up. Circulation / Cardiovascular Quality and Outcomes 10, e003458, 2017.

Brenner H, Jansen L, Saum KU, Holleczek B, Schöttker B: Vitamin D supplementation trials aimed at reducing mortality have much higher power when focusing on people with low serum 25-hydroxyvitamin D concentrations. Journal of Nutrition 147 (7), 1325-1333, 2017.

Brenner H, Werner S: Selecting a cutoff for colorectal cancer screening with a fecal immunochemical test. Clinical and Translational Gastroenterology 8 (8), e111, 2017.

Brenner H, Weberpals J, Jansen L: Epidemiologische Forschung mit Krebsregisterdaten, Überlebenszeitanalysen, Vergleich nationaler und internationaler Ergebnisse Epidemiological research - cancer registry data. Survival time analysis - comparison of national and international results. Onkologe 23 (4), 272-279, 2017.

Brenner H, Zwink N, Ludwig L, Hoffmeister M: Should screening colonoscopy be offered from age 50? Results from a statewide pilot project, and from a randomized intervention study. Deutsches Aerzteblatt International 114 (6), 94-100, 2017.

Brenner H, Niedermaier T, Chen H: Strong subsite-specific variation in detecting advanced adenomas by fecal immunochemical testing for hemoglobin. International Journal of Cancer 140 (9), 2015-2022, 2017.

Brenner,H., Chen,H.D.: Fecal occult blood versus DNA testing: indirect comparison in a colorectal cancer screening population. Clinical Epidemiology 9, 377-384, 2017.

Brouckaert O, Rudolph A, Laenen A, Keeman R, Bolla MK, …, Arndt V, …, Brenner H, …, Garcia-Closas M, Chang-Claude J, Lambrechts D, Neven P: Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study. Breast Cancer Research 19 (1), 119, 2017.

Brunner C, Davies NM, Martin RM, Eeles R, Easton D, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles G, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Donovan J, Hamdy FC, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, Collins A, Zuccolo L, the PRACTICAL Consortium: Alcohol Consumption and Prostate Cancer Incidence and Progression: A Mendelian Randomization Study. International Journal of Cancer 140, 75-85, 2017.

Butt J, Werner S, Willhauck-Fleckenstein M, Michel A, Waterboer T, Zörnig I, Boleij A, Dramsi S, Brenner H, Pawlita M: Serology of Streptococcus gallolyticus subspecies gallolyticus and its association with colorectal cancer precursors. International Journal of Cancer 141 (5), 897-904, 2017.

Carr P, Holleczek B, Stegmaier C, Brenner H, Hoffmeister M: Meat intake and risk of colorectal polyps: results from a large population based screening study in Germany. American Journal of Clinical Nutrition 105 (6), 1453-1461, 2017.

Carr PR, Jansen L, Bienert S, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M: Associations of red and processed meat intake with major molecular pathological features of colorectal cancer. European Journal of Epidemiology 32 (5), 409-418, 2017.

Chen H, Werner S, Brenner H: Fresh vs frozen samples and ambient temperature have little effect on detection of colorectal cancer or adenomas by a fecal immunochemical test in a colorectal cancer screening cohort in Germany. Clinical Gastroenterology and Hepatology 15 (10), 1547-1556, 2017.

Chen H, Qian J, Werner S, Cuk K, Knebel P, Brenner H: Development and validation of a panel of five proteins as blood biomarkers for early detection of colorectal cancer. Clinical Epidemiology 9, 517-526, 2017.

Chen T, Brenner H, Fallah M, Jansen L, Castro FA, Geiss K, Holleczek B, Katalinic A, Luttmann S, Sundquist K, Ressing M, Xu L, Hemminki K, GEKID Cancer Survival Working Group: Risk of second primary cancers in women diagnosed with endometrial cancer in German and Swedish cancer registries. International Journal of Cancer 141 (11), 2270-2280, 2017.

Cheriyamundath S, Raghaven R, Banerji A, Klika, K, Ulrich C, Owen R.W, Madassery J: Bioassay-guided isolation and evaluation of antiproliferative effects of (Z)-ethylidine-4, 6-dimethoxycoumaran-3-one from Pogostemon quadrifolius (Benth). Asian Pacific Journal of Cancer Prevention (18), 253-260, 2017.

Christiansen H, Brandt S, Walter V, Wabitsch M, Rothenbacher D, Brenner H, Schimmelmann BG, Hirsch O: Prediction of BMI at age 11 in a longitudinal sample of the Ulm Birth Cohort Study. PLoS ONE 12 (8), e0182338, 2017.

Dal Maso L, Tavilla A, Pacini F, Serraino D, van Dijk BAC, Chirlaque MD, Capocaccia R, Larranaga N, Colonna M, Agius D, Ardanaz E, Rubió-Casadevall J, Kowalska A, Virdone S, Mallone S, Amash H, De Angelis R, EUROCARE-5 Working Group, *Collaborators form DKFZ: Brenner H: Survival of 86,690 patients with thyroid cancer: A population-based study in 29 European countries from EUROCARE-5. European Journal of Cancer 77, 140-152, 2017.

Day FR, Thompson DJ, Helgason H, Chasman DI, Finucane H, Sulem P, Ruth KS, Whalen S, Sarkar AK, Albrecht E, Altmaier E, Amini M, Barbieri CM, Boutin T, Campbell A, Demerath E, Giri A, He C, Hottenga JJ, Karlsson R, Kolcic I, Loh PR, Lunetta KL, Mangino M, Marco B, McMahon G, Medland SE, Nolte IM, Noordam R, Nutile T, Paternoster L, Perjakova N, Porcu E, Rose LM, Schraut KE, Segre AV, Smith AV, Stolk L, Teumer A, Andrulis IL, Bandinelli S, Beckmann MW, Benitez J, Bergmann S, Bochud M, Boerwinkle E, Bojesen SE, Bolla MK, Brand JS, Brauch H, Brenner H, Broer L, Bruning T, Buring JE, Campbell H, Catamo E, Chanock S, Chenevix-Trench G, Corre T, Couch FJ, Cousminer DL, Cox A, Crisponi L, Czene K, Davey Smith G, de Geus EJCN, de Mutsert R, De Vivo I, Dennis J, Devilee P, Dos-Santos-Silva I, Dunning AM, Eriksson JG, Fasching PA, Fernandez-Rhodes L, Ferrucci L, Flesch-Janys D, Franke L, Gabrielson M, Gandin I, Giles GG, Grallert H, Gudbjartsson DF, Guenel P, Hall P, Hallberg E, Hamann U, Harris TB, Hartman CA, Heiss G, Hooning MJ, Hopper JL, Hu F, Hunter DJ, Ikram MA, Im HK, Jarvelin MR, Joshi PK, Karasik D, Kellis M, Kutalik Z, LaChance G, Lambrechts D, Langenberg C, Launer LJ, Laven JSE, Lenarduzzi S, Li J, Lind PA, Lindstrom S, Liu Y, Luan J, Magi R, Mannermaa A, Mbarek H, McCarthy MI, Meisinger C, Meitinger T, Menni C, Metspalu A, Michailidou K, Milani L, Milne RL, Montgomery GW, Mulligan AM, Nalls MA, Navarro P, Nevanlinna H, Nyholt DR, Oldehinkel AJ, O´ Mara TA, Padmanabhan S, Palotie A, Pedersen N, Peters A, Peto J, Pharoah PDP, Pouta A, Radice P, Rahman I, Ring SM, Robino A, Rosendaal FR, Rudan I, Rueedi R, Ruggiero D, Sala CF, Schmidt MK, Scott RA, Shah M, Sorice R, Southey MC, Sovio U, Stampfer M, Steri M, Strauch K, Tanaka T, Tikkanen E, Timpson NJ, Traglia M, Truong T, Tyrer JP, Uitterlinden AG, Edwards DRV, Vitart V, Volker U, Vollenweider P, Wang Q, Widen E, van Dijk KW, Willemsen G, Winqvist R, Wolffenbuttel BHR, Zhao JH, Zoledziewska M, Zygmunt M, Alizadeh BZ, Boomsma DI, Ciullo M, Cucca F, Esko T, Franceschini N, Gieger C, Gudnason V, Hayward C, Kraft P, Lawlor DA, Magnusson PKE, Martin NG, Mook-Kanamori DO, Nohr EA, Polasek O, Porteous D, Price AL, Ridker PM, Snieder H, Spector TD, Stockl D, Toniolo D, Ulivi S, Visser JA, Volzke H, Wareham NJ, Wilson JF, Spurdle AB, Thorsteindottir U, Pollard KS, Easton DF, Tung JY, Chang-Claude J, Hinds D, Murray A, Murabito JM, Stefansson K, Ong KK, Perry JRB: Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics 49 (6), 834-841, 2017.

Dimitrakopoulou VI, Tsilidis KK, Haycock PC, Dimou NL, Al-Dabhani K, …, Brenner H, …, Hoffmeister M, Kuhn T*, …, the PRACTICAL Consortium, Kraft P, Pierce BL, Schildkraut JM, on behalf of GECCO, PRACTICAL and the GAME-ON Network: CORECT, DRIVE, ELLIPSE, FOCI-OCAC and TRICL-ILCCO: Circulating vitamin D concentration and risk of seven cancers: a Mendelian randomization study. BMJ 359, j4761, 2017.

Fagerholm R, Khan S, Schmidt MK, Garcia-Closas M, Heikkila P, Saarela J, Beesley J, Jamshidi M, Aittomaki K, Liu J, Ali HR, Andrulis IL, Beckmann MW, Behrens S, Blows FM, Brenner H, Chang-Claude J, Couch FJ, Czene K, Fasching PA, Figueroa J, Floris G, Glendon G, Guo Q, Hall P, Hallberg E, Hamann U, Holleczek B, Hooning MJ, Hopper JL, Jager A, Kabisch M, Keeman R, Kosma VM, Lambrechts D, Lindblom A, Mannermaa A, Margolin S, Provenzano E, Shah M, Southey MC, Dennis J, Lush M, Michailidou K, Wang Q, Bolla MK, Dunning AM, Easton DF, Pharoah PD, Chenevix-Trench G, Blomqvist C, Nevanlinna H: TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer. Oncotarget 8 (11), 18381-18398, 2017.

Fehringer G, Brenner DR, Zhang ZF, Lee YCA, Matsuo K, ..., Brenner H, ..., Consonni D, Olsson A, Straif K, Hung RJ, Saum,K-U, ...: Alcohol and lung cancer risk among never smokers: A pooled analysis from the international lung cancer consortium and the SYNERGY study. International Journal of Cancer 140 (9), 1976-1984, 2017.

Freisling H, Arnold M, Soerjomataram I, O'Doherty M, Ordonez-Mena J, Bamia C, Kampman E, Leitzmann M, Romieu I, Kee F, Tsilidis K, Tjonneland A, Trichopoulou A, Boffetta P, Benetou V, Bueno-de-Mesquita HB, Huerta JM, Brenner H, Wilsgaard T, Jenab M: Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk: meta-analysis of individual participant data of seven prospective cohorts in Europe. British Journal of Cancer 116 (11), 1486-1497, 2017.

Gakidou,E., Afshin,A., Abajobir,A.A., Abate,K.H., Abbafati,C., Abbas,K.M., Abd-Allah,F., Abdulle,A.M., Abera,S.F., Aboyans,V., Abu-Raddad,L.J., Abu-Rmeileh,N.M.E., Abyu,G.Y., Adedeji,I.A., Adetokunboh,O., Afarideh,M., Agrawal,A., Agrawal,S., Kiadaliri,A.A., Ahmadieh,H., Ahmed,M.B., Aichour,A.N., Aichour,I., Aichour,M.T.E., Akinyemi,R.O., Akseer,N., Alahdab,F., Al-Aly,Z., Alam,K., Alam,N., Alam,T., Alasfoor,D., Alene,K.A., Ali,K., Alizadeh-Navaei,R., et al..., DKFZ-Member: Brenner H, et al: Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 390 (10100), 1345-1422, 2017.

Gao X, Thomsen H, Zhang Y, Breitling LP, Brenner H: The impact of methylation quantitative trait loci (mQTLs) on active smoking-related DNA methylation changes. Clinical Epigenetics 9, 87, 2017.

Gao X, Gao X, Zhang Y, Breitling LP, Schöttker B, Brenner H: Associations of self-reported smoking, cotinine levels and epigenetic smoking indicators with oxidative stress among older adults: a population-based study. European Journal of Epidemiology 32 (5), 443-456, 2017.

Gao X, Zhang Y, Saum KU, Schöttker B, Breitling LP, Brenner H: Tobacco smoking and smoking-related DNA methylation are associated with the development of frailty among older adults. Epigenetics 12 (2), 149-156, 2017.

Gao X, Zhang Y, Brenner H: Associations of Helicobacter pylori infection and chronic atrophic gastritis with accelerated epigenetic ageing in older adults. British Journal of Cancer 117 (8), 1211-1214, 2017.

Gatta G, Peris-Bonet, Visser O, Stiller C, Marcos-Gragera R, Sánchez MJ, Lacour B, Kaatsch P, Berrino F, Rutkowsky S, Botta L, and the EUROCARE-5 Working Group (Collaborator from DKFZ: Brenner H): Geographical variability in survival of European children with central nervous system tumours. European Journal of Cancer 82, 137-148, 2017. [

GBD 2015 Tobacco Collaborators*, *Collaborators from DKFZ: Brenner H, Schöttker B: Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: a systematic analysis from the Global Burden of Disease Study 2015. Lancet 389 (10082), 1885-1906, 2017.

Gu F, Zhang H, Hyland PL, Berndt S, Gapstur SM, Wheeler W, the ELLIPSE consortium, Amos CI, Bezieau S, Bickeböller H, Brenner H, Brennan P, Chang-Claude J, Conti DV, Doherty J, Gruber SB, Harrison TA, Hayes RB, Hoffmeister M, Houlston RS, Hung RJ, Jenkins MA, Kraft P, Lawrenson K, McKay J, Markt S, Mucci L, Phelan CM, Qu C, Risch A, Rossing MA, Wichmann HE, Shi J, Schernhammer E, Yu K, Landi MT, Caporaso NE: Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia. International Journal of Cancer 141 (9), 1794-1802, 2017.

Guo Q, Burgess S, Turman C, Bolla MK, Wang Q, Lush M, Abraham J, Aittomäki K, Andrulis IL, Apicella C, Arndt V, Barrdahl M, Benitez J, Berg CD, Blomqvist C, Bojesen SE, Bonanni B, Brand JS, Brenner H, Broeks A, Burwinkel B, Caldas C, Campa D, Canzian F, Chang-Claude J, Chanock SJ, Chin S-F, Couch FJ, Cox A, Cross SS, Cybulski C, Czene K, Darabi H, Devilee P, Diver WR, Dunning AM, Earl HM, Eccles DM, Ekici AB, Eriksson M, Evans DG, Fasching PA, Figueroa J, Flesch-Janys D, Flyger H, Gapstur SM, Gaudet MM, Giles GG, Glendon G, Grip M, Gronwald J, Haeberle L, Haiman CA, Hall P, Hamann U, Hankinson S, Hartikainen JM, Hein A, Hiller L, Hogervorst FB, Holleczek B, Hooning MJ, Hoover RN, Humphreys K, Hunter DJ, Hüsing A, Jakubowska A, Jukkola-Vuorinen A, Kaaks R, Kabisch M, Kataja V, kConFab/AOCS Investigators, Knight JA, Koppert LB, Kosma V-M, Kristensen VN, Lambrechts D, Le Marchand L, Li J, Lindblom A, Lindström S, Lissowska J, Lubinski J, Machiela MJ, Mannermaa A, Manoukian S, Margolin S, Marme F, Martens JWM, McLean C, Menendez P, Milne RL, Mulligan AM, Muranen TA, Nevanlinna H, Neven P, Nielsen SF, Nordestgaard BG, Olson JE, Perez JIA, Peterlongo P, Phillips K-A, Poole CJ, Pylkäs K, Radice P, Rahman N, Rüdiger T, Rudolph A, Sawyer EJ, Schumacher F, Seibold P, Seynaeve C, Shah M, Smeets A, Southey MC, Tollenaar RAEM, Tomlinson I, Tsimiklis H, Ulmer H-U, Vachon C, van den Ouweland AMW, Van’t Veer LJ, Wildiers H, Willett W, Winqvist R, Zamora MP, Chenevix-Trench G, Dörk T, Easton DF, Garcia-Closas M, Kraft P, Hopper JL, Zheng W, Schmidt MK, Pharoah PDP: Body mass index and breast cancer survival: a Mendelian randomization analysis. International Journal of Epidemiology 46 (6), 1814-1822, 2017.

Hajek A, Bock JO, Brenner H, Saum KU, Matschinger H, Haefeli WE, Quinzler R, Heider D, König HH: [Which Factors Affect Out-of-pocket Payments for Health Care Services Among Elderly Germans? Results of a Longitudinal Study]. Welche Faktoren beeinflussen die privaten Zuzahlungen zu Gesundheitsleistungen im Alter? Ergebnisse einer Längsschnittstudie. Gesundheitswesen 79 (2), e18-e25, 2017.

Heiss JA, Brenner H: Epigenome-wide discovery and evaluation of leukocyte DNA methylation markers for the detection of colorectal cancer in a screening setting. Clinical Epigenetics 9, 24, 2017.

Heiss JA, Brenner H: Impact of confounding by leukocyte composition on associations of leukocyte DNA methylation with common risk factors. Epigenomics 9 (5), 659-668, 2017.

Heiss JA, Breitling LP, Lehne B, Kooner JS, Chambers JC, Brenner H: Training a model for estimating leukocyte composition using whole blood DNA methylation and cell counts as reference. Epigenomics 9 (1), 13-20, 2017.

Hoffmeister M, Holleczek B, Zwink N, Stock C, Stegmaier C, Brenner H: Screening for Bowel Cancer: Increasing Participation via Personal Invitation  [Darmkrebsscreening - Steigerung der Teilnahmeraten durch persönliche Einladung. Eine randomisierte Interventionsstudie]. Deutsches Aerzteblatt International 114 (6), 87-93, 2017.

Jankovic N, Geelen A, Winkels RM, Mwungura B, Fedirko V, Jenab M, Illner AK, Brenner H, Ordonez-Mena JM, Kiefte-de Jong JC, Franco OH, Orfanos P, Trichopoulou A, Boffetta P, Agudo A, Peeters PH, Tjonneland A, Hallmans G, Bueno-de-Mesquita HB, Park Y, Feskens EJ, de Groot LC, Kampman E: Adherence to the WCRF/AICR dietary recommendations for cancer prevention and risk of cancer in elderly from Europe and the United States: A Meta-Analysis within the CHANCES project. Cancer Epidemiology Biomarkers and Prevention 26 (1), 136-144, 2017.

Jansen L*, Weberpals J*, Kuiper JG, Vissers PAJ, Wolkewitz M, Hoffmeister M, Brenner H. *Contributed equally: Pre- and post-diagnostic beta-blocker use and prognosis after colorectal cancer: Results from a population-based study. International Journal of Cancer 141 (1), 62-71, 2017.

Katsoulis M, Benetou V, Karapetyan T, Feskanich D, Grodstein F, Pettersson-Kymmer U, Eriksson S, Wilsgaard T, Jorgensen L, Ahmed LA, Schoettker B, Brenner H, Bellavia A, Wolk A, Kubinova R, Stegeman B, Bobak M, Boffetta P, Trichopoulou A: Excess mortality after hip fracture in elderly persons from Europe and the USA: the CHANCES project. Journal of Internal Medicine 281 (3), 300-310, 2017.

Kirchberg FF, Brandt S, Moß A, Peissner W, König W, Rothenbacher D, Brenner H, Koletzko B, Hellmuth C, Wabitsch M: Metabolomics reveals an entanglement of fasting leptin concentrations with fatty acid oxidation and gluconeogenesis in healthy children. PLoS ONE 12 (8), e0183185, 2017.

Krilaviciute A, Stock C, Brenner H: International variation in the prevalence of preclinical colorectal cancer: implications for predictive values of noninvasive screening tests and potential target populations for screening. International Journal of Cancer 141 (8), 1566-1575, 2017.

Lin HY, Chen DT, Huang PY, Liu YH, Ochoa A, Zabaleta J, Mercante DE, Fang Z, Sellers TA, Pow-Sang JM, Cheng CH, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Hamdy F, Pashayan N, Khaw KT, Stanford JL, Blot WJ, Thibodeau SN, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Kaneva R, Batra J, Teixeira MR, Pandha H, Lu YJ, Park JY: SNP interaction pattern identifier (SIPI): an intensive search for SNP-SNP interaction patterns. Bioinformatics 33 (6), 822-833, 2017.

Logan CA, Brandt S, Wabitsch M, Brenner H, Wiens F, Stahl S, Marosvölgyi T, Decsi T, Rothenbacher D, Genuneit J: New approach shows no association between maternal milk fatty acid composition and childhood wheeze or asthma. Allergy 72 (9), 1374-1383, 2017.

Logan CA, Bornemann R, König W, Reister F, Walter V, Fantuzzi G, Weyermann M, Brenner H, Genuneit J, Rothenbacher D: Gestational weight gain and fetal-maternal adiponectin, leptin, and CRP: results of two birth cohorts studies. Scientific Reports 7, 41847, 2017.

Maalmi H, Walter V, Jansen L, Chang-Claude J, Owen RW, Ulrich A, Schöttker B, Hoffmeister M, Brenner H: Relationship of very low serum 25-hydroxyvitamin D3 levels with long-term survival in a large cohort of colorectal cancer patients from Germany. European Journal of Epidemiology 32 (11), 961-971, 2017.

Maddock J, Zhou A, Cavadino A, Kuzma E, Bao Y, …, Schöttker B, ..., Saum, KU, Perna L, ..., Brenner H, Kumari M, Power C, Llewellyn DJ, Hyppönen E: Vitamin D and cognitive function: A mendelian randomisation study. Scientific Reports 7 (1), 13230, 2017.

Maierthaler M, Benner A, Hoffmeister M, Surowy H, Jansen L, Knebel P, Chang-Claude J, Brenner H, Burwinkel B: Plasma miR-122 and miR-200 family are prognostic markers in colorectal cancer. International Journal of Cancer 140 (1), 176-187, 2017.

Matsushita K, Ballew SH, Coresh J, Arima H, Ärnlöv J, Cirillo M, Ebert N, Hiramoto JS, Kimm H, Shlipak MG, Visseren FLJ, Gansevoort RT, Kovesdy CP, Shalev V, Woodward M, Kronenberg F, Chronic Kidney Disease Prognosis Consortium, Collaborators from the ESTHER study: Brenner H, Schöttker B, Rothenbacher D, Saum KU: Measures of chronic kidney disease and risk of incident peripheral artery disease: a collaborative meta-analysis of individual participant data. Lancet Diabetes and Endocrinology 5 (9), 718-728, 2017.

Mayer T, Meid AD, Saum KU, Brenner H, Schöttker B, Seidling HM, Haefeli WE: Comparison of nine instruments to calculate anticholinergic load in a large cohort of older outpatients: association with cognitive and functional decline, falls, and use of laxatives. American Journal of Geriatric Psychiatry 25 (5), 531-540, 2017.

Meistere I, Werner S, Zayakin P, Silina K, Rulle U, Pismennaja A, Šantare D, Kikuste I, Isajevs S, Leja M, Kupcinskas L, Kupcinskas J, Jonaitis L, Wu CY, Brenner H, Line A, Kalnina Z: The prevalence of cancer-associated autoantibodies in patients with gastric cancer and progressive grades of premalignant lesions. Cancer Epidemiology Biomarkers and Prevention 26 (10), 1564-1574, 2017.

Michailidou K, Lindstrom S, Dennis J, Beesley J, Hui S, Kar S, Lemacon A, Soucy P, Glubb D, Rostamianfar A, Bolla MK, Wang Q, Tyrer J, Dicks E, Lee A, Wang Z, Allen J, Keeman R, Eilber U, French JD, Qing Chen X, Fachal L, McCue K, McCart Reed AE, Ghoussaini M, Carroll JS, Jiang X, Finucane H, Adams M, Adank MA, Ahsan H, Aittomaki K, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Arun B, Auer PL, Bacot F, Barrdahl M, Baynes C, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bernstein L, Blomqvist C, Bogdanova NV, Bojesen SE, Bonanni B, Borresen-Dale AL, Brand JS, Brauch H, Brennan P, Brenner H, Brinton L, Broberg P, Brock IW, Broeks A, Brooks-Wilson A, Brucker SY, Bruning T, Burwinkel B, Butterbach K, Cai Q, Cai H, Caldes T, Canzian F, Carracedo A, Carter BD, Castelao JE, Chan TL, David Cheng TY, Seng Chia K, Choi JY, Christiansen H, Clarke CL, Collee M, Conroy DM, Cordina-Duverger E, Cornelissen S, Cox DG, Cox A, Cross SS, Cunningham JM, Czene K, Daly MB, Devilee P, Doheny KF, Dork T, Dos-Santos-Silva I, Dumont M, Durcan L, Dwek M, Eccles DM, Ekici AB, Eilber U, Eliassen AH, Ellberg C, Elvira M, Engel C, Eriksson M, Fasching PA, Figueroa J, Flesch-Janys D, Fletcher O, Flyger H, Fritschi L, Gaborieau V, Gabrielson M, Gago-Dominguez M, Gao YT, Gapstur SM, Garcia-Saenz JA, Gaudet MM, Georgoulias V, Giles GG, Glendon G, Goldberg MS, Goldgar DE, Gonzalez-Neira A, Grenaker Alnaes GI, Grip M, Gronwald J, Grundy A, Guenel P, Haeberle L, Hahnen E, Haiman CA, Hakansson N, Hamann U, Hamel N, Hankinson S, Harrington P, Hart SN, Hartikainen JM, Hartman M, Hein A, Heyworth J, Hicks B, Hillemanns P, Ho DN, Hollestelle A, Hooning MJ, Hoover RN, Hopper JL, Hou MF, Hsiung CN, Huang G, Humphreys K, Ishiguro J, Ito H, Iwasaki M, Iwata H, Jakubowska A, Janni W, John EM, Johnson N, Jones K, Jones M, Jukkola-Vuorinen A, Kaaks R, Chang-Claude J, et al.: Association analysis identifies 65 new breast cancer risk loci. Nature 551 (7678), 92-94, 2017.

Minicozzi P, Innos K, Sánchez MJ, Trama A, Walsh PM, Marcos-Gragera R, Dimitrova N, Botta L, Visser O, Rossi S, Tavilla A, Sant M, The EUROCARE-5 Working Group.* *Collaborator from DKFZ: Brenner H: Quality analysis of population-based information on cancer stage at diagnosis across Europe, with presentation of stage-specific cancer survival estimates: A EUROCARE-5 study. European Journal of Cancer 84, 335-353, 2017.

Mons U, Brenner H: Demographic ageing and the evolution of smoking-attributable mortality: the example of Germany. Tobacco Control 26 (4), 455-457, 2017.

Mons U, Muezzinler A, Schoettker B, Dieffenbach AK, Butterbach K, Schick M, Peasey A, De Vivo I, Trichopoulou A, Boffetta P, Brenner H: Leukocyte Telomere Length and All-Cause, Cardiovascular Disease, and Cancer Mortality: Results From Individual-Participant-Data Meta-Analysis of 2 Large Prospective Cohort Studies. American Journal of Epidemiology 185 (12), 1317-1326, 2017.

Muhlack DC, Hoppe LK, Weberpals J, Brenner H, Schöttker B: Association of potentially inappropriate medication at older age with cardiovascular events and overall mortality: a systematic review and meta-analysis of cohort studies. Journal of the American Medical Directors Association 18 (3), 211-220, 2017.

Muranen TA, Greco D, Blomqvist C, Aittomaki K, Khan S, Hogervorst F, Verhoef S, Pharoah PD, Dunning AM, Shah M, Luben R, Bojesen SE, Nordestgaard BG, Schoemaker M, Swerdlow A, Garcia-Closas M, Figueroa J, Dork T, Bogdanova NV, Hall P, Li J, Khusnutdinova E, Bermisheva M, Kristensen V, Borresen-Dale AL, Investigators N, Peto J, Dos Santos Silva I, Couch FJ, Olson JE, Hillemans P, Park-Simon TW, Brauch H, Hamann U, Burwinkel B, Marme F, Meindl A, Schmutzler RK, Cox A, Cross SS, Sawyer EJ, Tomlinson I, Lambrechts D, Moisse M, Lindblom A, Margolin S, Hollestelle A, Martens JW, Fasching PA, Beckmann MW, Andrulis IL, Knight JA, Investigators K, Anton-Culver H, Ziogas A, Giles GG, Milne RL, Brenner H, Arndt V, Mannermaa A, Kosma VM, Chang-Claude J, Rudolph A, Devilee P, Seynaeve C, Hopper JL, Southey MC, John EM, Whittemore AS, Bolla MK, Wang Q, Michailidou K, Dennis J, Easton DF, Schmidt MK, Nevanlinna H: Genetic modifiers of CHEK2*1100delC-associated breast cancer risk. Genetics in Medicine 19 (5), 599-603, 2017.

Nagel G, Fallah M, Erdmann F, Heier M, Meisinger Ch, Mayer B, Rothenbacher D: Wie könnten die Potentiale registerbasierter Studien in Deutschland besser ausschöpft werden?. Deutsches Aerzteblatt (18), 114-114, 2017.

NCD Risk Factor Collaboration (NCD-RisC)*Collaborators on behalf of the ESTHER study: Brenner H, Saum KU, Kaaks, R: Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1,479 population-based measurement studies with 19.1 million participants. Lancet 389 (10064), 37-55, 2017.

Niedermaier T, Weigl K, Hoffmeister M, Brenner H: Diagnostic performance of flexible sigmoidoscopy combined with fecal immunochemical test in colorectal cancer screening: meta-analysis & modeling. European Journal of Epidemiology 32 (6), 481-493, 2017.

Ordonez-Mena JM, Schöttker B, Saum KU, Holleczek B, Burwinkel B, Wang TJ, Brenner H: No association of vitamin D pathway genetic variants with cancer risks in a population-based cohort of German older adults. Cancer Epidemiology Biomarkers and Prevention 26 (9), 1459-1461, 2017.

Ordónez-Mena JM, Maalmi H, Schoettker B, Saum KU, Holleczek B, Wang TJ, Burwinkel B, Brenner H: Genetic variants in the vitamin D pathway, 25(OH)D levels, and mortality in a large population-based cohort study. Journal of Clinical Endocrinology and Metabolism 102 (2), 470-477, 2017.

Pfetsch V, Sanin V, Jaensch A, Dallmeier D, Mons U, Brenner H, König W, Rothenbacher D: Increased plasma concentrations of soluble ST2 independently predict mortality but not cardiovascular events in stable coronary heart disease patients: 13-year follow-up of the KAROLA study. Cardiovascular Drugs and Therapy 31 (2), 167-177, 2017.

Pulte D, Jansen L, Brenner H: Population level differences in rectal cancer survival in uninsured patients are partially explained by differences in treatment. Oncologist 22 (3), 351-358, 2017.

Pulte D, Jansen L, Brenner H: Social disparities in survival after diagnosis with colorectal cancer: Contribution of race and insurance status. Cancer Epidemiology 48, 41-47, 2017.

Pulte D, Weberpals J, Jansen L, Luttmann S, Holleczek B, Nennecke A, Ressing M, Katalinic A, Brenner H, for the GEKID Cancer Survival Working Group: Survival for patients with rare hematologic malignancies: changes in the early 21st century. European Journal of Cancer 84, 81-87, 2017.

Pulte D, Castro FA, Brenner H, Jansen L: Outcome disparities by insurance type for patients with acute myeloblastic leukemia. Leukemia Research 56, 75-81, 2017.

Saum KU, Schoettker B, Meid A, Holleczek B, Haefeli W, Hauer K, Brenner H: Is polypharmacy associated with frailty in older people? Results from the ESTHER Cohort Study. Journal of the American Geriatrics Society 65 (2), e27-e32, 2017.

Schöttker B, Saum KU, Muhlack DC, Hoppe LK, Holleczek B, Brenner H: Polypharmacy and mortality: new insights from a large cohort of older adults by detection of effect modification by multi-morbidity and comprehensive correction of confounding by indication. European Journal of Clinical Pharmacology 73, 1041-1048, 2017.

Shimelis H, Mesman RLS, Von Nicolai C, Ehlen A, Guidugli L, Martin C, Calleja FMGR, Meeks H, Hallberg E, Hinton J, Lilyquist J, Hu C, Aalfs CM, Aittomaki K, Andrulis I, Anton-Culver H, Arndt V, Beckmann MW, Benitez J, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Brauch H, Brennan P, Brenner H, Broeks A, Brouwers B, Bruning T, Burwinkel B, Chang-Claude J, Chenevix-Trench G, Cheng CY, Choi JY, Collee JM, Cox A, Cross SS, Czene K, Darabi H, Dennis J, Dork T, Dos-Santos-Silva I, Dunning AM, Fasching PA, Figueroa J, Flyger H, Garcia-Closas M, Giles GG, Glendon G, Guenel P, Haiman CA, Hall P, Hamann U, Hartman M, Hogervorst FB, Hollestelle A, Hopper JL, Ito H, Jakubowska A, Kang D, Kosma VM, Kristensen V, Lai KN, Lambrechts D, Marchand LL, Li J, Lindblom A, Lophatananon A, Lubinski J, Machackova E, Mannermaa A, Margolin S, Marme F, Matsuo K, Miao H, Michailidou K, Milne RL, Muir K, Neuhausen SL, Nevanlinna H, Olson JE, Olswold C, Oosterwijk JJC, Osorio A, Peterlongo P, Peto J, Pharoah PDP, Pylkas K, Radice P, Rashid MU, Rhenius V, Rudolph A Sangrajrang S, Sawyer EJ, Schmidt MK, Schoemaker MJ, Seynaeve C, Shah M, Shen CY, Shrubsole M, Shu XO, Slager S, Southey MC, Stram DO, Swerdlow A, Teo SH, Tomlinson I, Torres D, Truong T, van Asperen CJ, van der Kolk LE, Wang Q, Winqvist R, Wu AH, Yu JC, Zheng W, Zheng Y, Leary J, Walker L, Foretova L, Fostira F, Claes KBM, Varesco L, Moghadasi S, Easton DF, Spurdle A, Devilee P, Vrieling H, Monteiro ANA, Goldgar DE, Carreira A, Vreeswijk MPG, Couch FJ: BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer. Cancer Research 77 (11), 2789-2799, 2017.

Skender S, Boehm J, Schrotz-King P, Chang-Claude J, Siegel EM, Steindorf K, Owen RW, Ose J, Hoffmeister M, Brenner H, Ulrich CM: Plasma 25-hydroxyvitamin D3 levels in colorectal cancer patients and associations with physical activity. Nutrition and Cancer 69 (2), 229-237, 2017.

Sluik D, Jankovic N, Hughes M, O'Doherty MG, Schöttker B, ..., Brenner H, ..., Iacoviello L, Boffetta P, Kee F, Feskens EJM: Alcoholic beverage preference and diabetes incidence across Europe: the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) project. European Journal of Clinical Nutrition 71 (5), 659-668, 2017.

Steele CJ, Schöttker B, Marshall AH, Kouvonen A, O' Doherty MG, Mons U, Saum KU, Boffetta P, Trichopoulou A, Brenner H*, Kee F*, (*shared last authorship): Education achievement and type 2 diabetes - What mediates the relationship in older adults? Data from the ESTHER study: a population-based cohort study. BMJ open 7 (4), e013569, 2017.

Taylor AE, Martin RM, Geybels MS, Stanford JL, Shui I, Eeles R, Easton DF, Kote-Jarai Z, Al Olama AA, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pashayan N, Khaw KT, Blot W, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Park J, Kaneva R, Batra J, Teixeira MR, Pandha H, and the PRACTIAL Consortium, Donovan J, Munafò MR: Investigating the possible causal role of coffee consumption with prostate cancer risk and progression using Mendelian randomization analysis. International Journal of Cancer 140 (2), 322-328, 2017.

Thomas B, Matsushita K, Abate KH, Al-Aly Z, Ärnlöv J, …, Brenner H, …, Schöttker B, …, Vos T, Global Burden of Disease 2013 GFR Collaborators, CKD Prognosis Consortium, Global Burden of Disease Genitourinary Expert Group: Global cardiovascular and renal outcomes of reduced GFR. Journal of the American Society of Nephrology 28 (7), 2167-2179, 2017.

Toth R, Scherer D, Kelemen LE, Risch A, Hazra A, Balavarca Y, Issa JJ, Moreno V, Eeles RA, Ogino S, Wu X, Ye Y, Hung RJ, Goode EL, Ulrich CM: Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium. Cancer Epidemiology Biomarkers and Prevention 26 (6), 816-825, 2017.

Walter V, Jansen L, Knebel P, Chang-Claude J, Hoffmeister M, Brenner H: Physical activity and survival of colorectal cancer patients: population-based study from Germany. International Journal of Cancer 140 (9), 1985-1997, 2017.

Weberpals J, Jansen L, van Herk-Sukel MPP, Kuiper JG, Aarts MJ, Vissers PAJ, Brenner H: Immortal time bias in pharmacoepidemiological studies on cancer patient survival: empirical illustration for beta-blocker use in four cancers with different prognosis. European Journal of Epidemiology 32 (11), 1019-1031, 2017.

Weberpals J, Jansen L, Haefeli WE, Hoffmeister M, Wolkewitz M, van Herk-Sukel M, Vissers PAJ, Brenner H: Pre- and post-diagnostic ß-blocker use and lung cancer survival: A population-based cohort study. Scientific Reports 7, 2911, 2017.

Weberpals J*, Pulte D*, Jansen L, Luttmann S, Holleczek B, Nennecke A, Ressing M, Katalinic A, Merz M, Brenner H, for the GEKID Cancer Survival Working Group *Contributed equally to the paper: Survival of patients with lymphoplasmacytic lymphoma and solitary plasmacytoma in Germany and the United States in the early 21st century. Haematologica 102, e229-e232, 2017.

Weischenfeldt J, Dubash T, Drainas A, Mardin B, Chen Y, Stuetz A, Waszak S, Bosco G, Halvorsen AR, Raeder B, Efthymiopoulos T, Brenner H, Brustugun OT, Dieter S, Northcott P, Petersen I, Pfister S, Schneider M, Solberg S, Thunnissen E, Weichert W, Zichner T, Thomas R, Peifer M, Helland A, Ball C, Jechlinger M, Sotillo R, Glimm H, Siegl C, Korbel J: Pan-cancer analysis of somatic copy number alterations implicates IRS4 and IGF2 in enhancer hijacking. Nature Genetics 49 (1), 65-74, 2017.

Wieland, E.*, Rodriguez-Vita, J.*, Liebler, S.S., Mogler, C.: Moll, I., Herberich, S.E., Espinet, E., Herpel, E., Menuchin, A., Chang-Claude, J., Hoffmeister, M., Gebhardt, C., Brenner, H., Trumpp, A., Siebel, C.W., Hecker, M., Utikal, J., Sprinzak, D., Fischer, A.: Endothelial Notch1 activity facilitates metastasis. Cancer Cell 31 (3), 355-367, 2017.

Winter A, Sirri E, Jansen L, Wawroschek F, Kieschke J, Castro FA, Krilaviciute A, Holleczek B, Emrich K, Waldmann A, Brenner H, for the GEKID Cancer Survival Working Group: Comparison of prostate cancer survival in Germany and the United States: Can differences be attributed to differences in stage dristibutions?. BJU International 119 (4), 550-559, 2017.

Zewinger S, Kleber ME, Tragante V, McCubrey RO, Schmidt AF, ..., Mons U, ..., Brenner H, ..., Breitling, L, Fliser D, März W, Scharnagl H, Speer T: Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. Lancet Diabetes and Endocrinology 5 (7), 534-543, 2017.

Zhang Y, Hapala J, Brenner H, Wagner W: Individual CpG sites that are associated with age and life expectancy become hypomethylated upon aging. Clinical Epigenetics 9, 9, 2017.

Zhang Y, Wilson R, Heiss J, Breitling LP, Saum KU, Schoettker B, Holleczek B, Waldenberger M, Peters A, Brenner H: DNA methylation signatures in peripheral blood strongly predict all-cause mortality. Nature Communications 8, 14617, 2017.

Zhou L, Tian Y, Fu JJ, Jiang YY, Bai YM, Zhang ZH, Hu XH, Lian HW, Guo M, Yang ZX, Zhao LC: Validation of spot urine in predicting 24-h sodium excretion at the individual level. American Journal of Clinical Nutrition 105 (6), 1291-1296, 2017.

Zhou L, Liu H, Wen X, Peng Y, Tian Y, Zhao L: Effects of metformin on blood pressure in nondiabetic patients: a meta-Analysis of randomized controlled trials. Journal of Hypertension 35 (1), 18-26, 2017.

Zuber V, Bettella F, Witoelar A, PRACTICAL Consortium, CRUK GWAS, BCAC Consortium, TRICL Consortium, Andreassen OA, Mills IG, Urbanucci A, *Collaborators from DKFZ: Brenner H: Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer. BMC Genomics 18 (1), 270, 2017.

Zwink N, Holleczek B, Stegmaier C, Hoffmeister M, Brenner H: Complication rates in colonoscopy screening for cancer - a prospective cohort study of complications arising during the procedure and in the ensuing four weeks. Deutsches Aerzteblatt International 114 (18), 321-327, 2017.

Zwink N, Stock C, Birkner B, Hoffmeister M, Brenner H: Screening colonoscopy volume and detection of colorectal neoplasms: A state-wide study from Bavaria, Germany. European Journal of Cancer Prevention 26 (3), 181-188, 2017.

Bhardwaj M, Erben V, Schrotz-King P, Brenner H: Cell line secretome and tumor tissue proteome markers for early detection of colorectal cancer: a systematic review. Cancers 9 (11), 156, 2017.

Bhardwaj M, Gies A, Werner S, Schrotz-King P, Brenner H: Blood-based protein signatures for early detection of colorectal cancer: A systematic review. Clinical and Translational Gastroenterology 8 (11), e128, 2017.

Chen C, Läcke E, Stock C, Hoffmeister M, Brenner H: Colonoscopy and sigmoidoscopy use among older adults in different countries: a systematic review. Preventive Medicine 103, 33-42, 2017.

Babaei M, Balavarca Y, Jansen L, Sjövall A, Bos A, Van de Velde T, Moreau M, Gabriel L, Goncalves AF, Bento MJ, Ulrich CM, Schrotz-King P, Lemmens V, Glimelius B, Brenner H: Neoadjuvant therapy in rectal cancer patients with clinical stage II-III across European countries: variations and outcomes. Clinical Colorectal Cancer , 2017.

Babaei M, Balavarca Y, Jansen L, Lemmens V, van Erning FN, van Eycken L, Vaes E, Sjövall A, Glimelius B, Ulrich CM, Schrotz-King P, Brenner H: Administration of adjuvant chemotherapy for stage II-III colon cancer patients: a European population-based study. International Journal of Cancer , 2017.

Bock JO, Hajek A, Saum KU, Matschinger H, Brenner H, Holleczek B, Haefeli WE, Heider D, König HH: Frailty and health care costs - longitudinal results of a prospective cohort study. Age and Ageing , 2017.

Chen C, Stock C, Hoffmeister M, Brenner H: Public health impact of colonoscopy use on colorectal cancer mortality in Germany and the United States. Gastrointestinal Endoscopy , 2017.

Chen T, Brenner H, Fallah M, Jansen L, Castro FA, Geiss K, Holleczek B, Katalinic A, Luttmann S, Sundquist K, Ressing M, Xu L, Hemminki K, GEKID Cancer Survival Working Group: Response: Methods for second primary cancers evaluation have to be standardized (IJC-17-2354). International Journal of Cancer , 2017.

GBD 2016 Causes of Death Collaborators: Global, regional, and national age - sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016. International Journal of Cancer , 2017.

Gies A, Bhardwaj M, Stock C, Schrotz-King P, Brenner H: Quantitative fecal immunochemical tests for colorectal cancer screening. International Journal of Cancer , 2017.

Gies A, Cuk K, Schrotz-King P, Brenner H: Direct comparison of diagnostic performance of 9 quantitative fecal immunochemical tests for colorectal cancer screening. Gastroenterology , 2017.

Gigic B, Boeing H, Toth R, Böhm J, Habermann N, Scherer D, Schrotz-King P, Abbenhardt-Martin C, Skender S, Brenner H, Chang-Claude J, Hoffmeister M, Syrjala K, Jacobsen PB, Schneider M, Ulrich A, Ulrich CM: Associations between dietary patterns and longitudinal quality of life changes in colorectal cancer patients: the ColoCare study. Nutrition and Cancer , 2017.

Gündert M, Edelmann D, Benner A, Jansen L, Jia M, Walter V, Knebel P, Herpel E, Chang-Claude J, Hoffmeister M, Brenner H, Burwinkel B: Genome-wide DNA methylation analysis reveals a prognostic classifier for non-metastatic colorectal cancer (ProMCol classifier). Gut , 2017.

Hajek A, Bock JO, Saum KU, Schöttker B, Brenner H, Heider D, König HH: Unterschiede in der Morbidität nach Krankenversichertenstatus im Alter. Gesundheitswesen , 2017.

Huang L, Jansen L, Balavarca Y, Molina-Montes E, Babaei M, van der Geest L, Lemmens V, Van Eycken L, De Schutter H, Johannesen TB, Fristrup CW, Mortensen MB, Zakelj MP, Zadnik V, Becker N, Hackert T, Mägi M, Cassetti T, Sassatelli R, Grützmann R, Merkel S, Goncalves AF, Bento MJ, Hegyi P, Lakatos G, Szentesi A, Moreau M, van de Velde T, Broeks A, Sant M, Minicozzi P, Mazzaferro V, Real FX, Carrato A, Molero X, Besselink MG, Malats N, Büchler MW, Schrotz-King P, Brenner H: Resection of pancreatic cancer in Europe and the US: an international large-scale study highlighting large variations. Gut , 2017.

Jiao,X., Aravidis,C., Marikkannu,R., Rantala,J., Picelli,S., Adamovic,T., Liu,T., Maguire,P., Kremeyer,B., Luo,L., von Holst,S., Kontham,V., Brenner,H, Arndt,V, Thutkawkorapin,J., Margolin,S., Du,Q., Lundin,J., Michailidou,K., Bolla,M.K., Wang,Q., Dennis,J., Lush,M., Ambrosone,C.B., Andrulis,I.L., Anton-Culver,H., Antonenkova,N.N., Arndt,V., Beckmann,M.W., Blomqvist,C., Blot, Boeckx,B., Bojesen,S.E., Bonanni,B., Brand,J.S., Brauch,H., Brenner,H., Broeks,A., Brüning,T., Burwinkel,B., Cai,Q., Chang-Claude,J., NBCS Collaborators, Couch,F.J., Cox,A., Cross,S.S., Deming-Halverson,S.L., Devilee,P., dos-Santos-Silva,I., Dörk,T., Eriksson,M., Fasching,P.A., Figueroa,J., Flesch-Janys,D., Flyger,H., Gabrielson,M., Montserrat García-Closas,M., Giles,G.G., González-Neira,A., Pascal Guénel,P., Guo,Q., Gündert,M., Haiman,C.A., Hallberg,E., Hamann,U., Harrington,P., Hooning,M.J., Hopper,J.L., Huang,G., Jakubowska,A., Jones,M.E., Kerin,M.J., Kosma,V.-M., Kristensen,V.N., Lambrechts,D., Le Marchand,L., Lubinski,J., Mannermaa,A., Martens,J.W.M., Meindl,A., Milne,R.L., Mulligan,A.M., Neuhausen,S.L., Nevanlinna,H., Peto,J., Pylkäs,K., Radice,P., Rhenius,V., Sawyer,E.J., Schmidt,M.K., Schmutzler,R.K., Seynaeve,C., Shah,M., Simard,J., Southey,M.C., Swerdlow,A.J., Truong,T., Wendt,C., Winqvist,R., Zheng,W., kConFab/AOCS Investigators, Benitez,J., Dunning,A.M., Pharoah,P.D.P., Easton,D.F., Czene,K., Hall,P., Lindblom,A.: PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1. Oncotarget , 2017.

NCD Risk Factor Collaboration (NCD-RisC).* *Collaborators on behalf of the ESTHER study: Brenner H, Saum KU: Worldwide trends in childrens and adolescents body mass index, underweight, overweight and obesity, in comparison with adults, from 1975 to 2016: a pooled analysis of 2,416 population-based measurement studies with 128.9 million participants. Lancet , 2017.

Niedermaier T, Weigl K, Hoffmeister M, Brenner H: Diagnostic performance of once-only flexible sigmoidoscopy combined with fecal immunochemical test in a large colorectal cancer screening population. Epidemiology , 2017.

Niedermaier T, Weigl K, Hoffmeister M, Brenner H: Fecal immunochemical tests in combination with blood tests for colorectal cancer and advanced adenoma detection - systematic review. United European Gastroenterology Journal , 2017.

Ordóñez-Mena JM, Walter V, Schöttker B, Jenab M, O’Doherty MG, Kee F, Bueno-de-Mesquita B, Peeters PHM, Stricker BH, Ruiter R, Hofman A, Söderberg S, Jousilahti P, Kuulasmaa K, Freedman ND, Wilsgaard T, Wolk A, Nilsson LM, Tjonneland A, Quirós JR, van Duijnhoven FJB, Siersema PD, Boffetta P, Trichopoulou A, Brenner H: Impact of prediagnostic smoking and smoking cessation on colorectal cancer prognosis: a meta-analysis of individual patient data from cohorts within the CHANCES consortium. Annals of Oncology , 2017.

Papadimitriou N, Tsilidis KK, Orfanos P, Benetou V, Ntzani EE, Soerjomataram I, Künn-Nelen A, Pettersson-Kymmer U, Eriksson S, Brenner H, Schöttker B, Saum KU, Holleczek B, Grodstein FD, Feskanich D, Orsini N, Wolk A, Bellavia A, Wilsgaard T, Jorgensen L, Boffetta P, Trichopoulos D, Trichopoulou A: Burden of hip fracture using disability adjusted life-years in a large consortium of prospective cohorts. Lancet Public Health , 2017.

Pulte D, Jansen L, Brenner H: Disparities in colon cancer survival by insurance type: a population based analysis. Diseases of the Colon and Rectum , 2017.

Rahbari NN*, Carr PR*, Jansen L, Chang-Claude J, Weitz J, Hoffmeister M, Brenner H *Contributed equally: Time of metastasis and outcome in colorectal cancer. Annals of Surgery , 2017.

Rudolph A, Song M, Brook MN, Milne RL, Mavaddat N, ..., Brenner H, Arndt V, ..., Easton DF, Chatterjee N, Chang-Claude J, Garcia-Closas M: Joint associations of a polygenic risk score and envionmental risk factors for breast cancer in the Breast Cancer Consortium. International Journal of Epidemiology , 2017.

Schumacher FR, Al Olama AA, Berndt SI, Benlloch S, Ahmed M, Brenner H, Cuk K, Holleczek B, Maier C, Luedeke M, Schnoeller T, Kim J, Logothetis CJ, John EM, Teixeira MR, Paulo P, Cardoso M, Neuhausen SL, Steele L, Ding YC, De Ruyck K, De Meerleer G, Ost P, Razack A, Lim J, Teo S-H, Lin DW, Newcomb LF, Canary PASS Investigators, Lessel D, Gamulin M, Kulis T, Kaneva R, Usmani N, Slavov C, Mitev V, Parliament M, Claessens F, Joniau S, Van den Broeck T, Larkin S, Townsend PA, Aukim-Hastie C, Gago Dominguez M, Esteban Castelao JE, Martinez ME, Roobol MJ, Jenster G, van Schaik RHN, Menegaux F, Truong T, Akoli Koudou Y, The Profile Study Steering Committee, Xu J, Khaw K-T, Cannon-Albright L, Pandha H, Michael A, Kierzek A, Thibodeau SN, McDonnell SK, Schaid DJ, Lindström S, Chen C, Ma J, Hunter DJ, Riboli E, Siddiq A, Canzian F: Prostate cancer meta-analysis of more than 140,000, men identifies 63 novel prostate cancer susceptibility loci. Nature Genetics , 2017.

Seibert TM, Fan CC, Wang Y, Zuber V, Karunamuni R, …, Brenner H, Cuk K, Saum KU, …, Andreassen OA, Dale AM, The PRACTICAL Consortium: Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large-scale cohorts. British Medical Journal , 2017.

Weigl K, Chang-Claude J, Knebel P, Hsu L, Hoffmeister M, Brenner H: Strongly enhanced colorectal cancer risk stratification by combining family history and genetic risk score. Clinical Epidemiology , 2017.

Radde K, Gottschalk A, Bussas U, Schülein S, Schriefer D, Seifert U, Neumann A, Kaiser M, Blettner M, Klug SJ. Invitation to cervical cancer screening does increase participation in Germany: Results from the MARZY study. International journal of cancer. 2016;139(5):1018–30. Epub 2016/04/17. pmid:27083776.

Brenner H, Castro FA, Eberle A, Emrich K, Holleczek B, Katalinic A, Jansen L., for the GEKID Cancer Survival Workgroup. Death certificate only proportions should be age adjusted in studies comparing cancer survival across populations and over time. European Journal of Cancer 2016; 52:102-108.

Thompson DJ, O'Mara TA, Glubb DM, Painter JN, Cheng T, ..., Brenner H, ..., Tomlinson I, Dowsett M, Easton DF, Spurdle AB. CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer. Endocrine-Related Cancer 2016; 23:77-91.

Florath I, Butterbach K, Heiss JA, Bewerunge-Hudler M, Zhang Y, Schöttker B, Brenner H. Type 2 diabetes and leucocyte DNA methylation: An epigenome-wide association study in over 1500 older adults. Diabetologia 2016; 59:130-138.

Zhang Y, Schöttker B, Florath I, Stock C, Butterbach K, Holleczek B, Mons U, Brenner H. Smoking-associated DNA methylation biomarkers and their predictive value for all-cause and cardiovascular mortality. Environmental Health Perspectives 2016; 124:67-74.

Carr PR, Jansen L, Walter V, Kloor M, Roth W, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M. Association of red and processed meat with survival after colorectal cancer and differences according to timing of dietary assessment. American Journal of Clinical Nutrition 2016; 103:192-200.

Mons U, Muscat JE, Modesto J, Richie JP, Brenner H. Effect of smoking reduction and cessation on the plasma levels of the oxidative stress biomarker glutathione - post-hoc analysis of data from a smoking cessation trial. Free Radical Biology & Medicine 2016; 91:172-177.

Müezzinler A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H, Boukamp P, Holleczek B, Stegmaier C, Brenner H. Body mass index and leukocyte telomere length dynamics among older adults: Results from the ESTHER cohort. Experimental Gerontology 2016; 74:1-8.

Phipps A, Passarelli MN, Chan AT, Harrison TA, Jeon J, Hutter CM, Berndt SI, Brenner H, Caan BJ, Campbell PT, Chang-Claude J, Chanock SJ, Cheadle JP, Curtis KR, Duggan D, Fisher D, Fuchs CS, Gala M, Giovannucci EL, Hayes RB, Hoffmeister M, Hsu L, Jacobs EJ, Jansen L, Kaplan R, Kap L, Maughan TS, Potter JD, Schoen RE, Seminara D, Slattery ML, West H, White E, Peters U, Newcomb PA. Common genetic variation and survival after colorectal cancer diagnosis: a genome-wide analysis. Carciogenesis 2016; 37:87-95.

Carr P, Walter V, Brenner H, Hoffmeister M. Meat subtypes and their association with colorectal cancer: systematic reveiw and meta-analysis. International Journal of Cancer 2016; 138:293-302.

Schöttker B, Saum KU, Jansen EHJM, Holleczek B, Brenner H. Associations of metabolic, inflammatory and oxidative stress markers with total morbidity and multi-morbidity in a large cohort of older German adults. Age and Ageing 2016; 45:127-135.

Pattaro C, Teumer A, Gorski M, Chu AY, Li M, ..., Brenner H, ..., Butterbach K, ..., Köttgen A, Kao L, Fox CS. Genetic association at 53 loci highlight cell types and biologic pathways for kidney function. Nature Communications 2016; 7:10023.

Haug U, Rösch T, Hoffmeister M, Katalinic A, Brenner H, Becker N. Einführung eines organisierten Darmkrebs-Screenings in Deuschland: Chancen und Herausforderungen. Das Gesundheitswesen (in press).

Purrington KS, Slettedahl S, Bolla MK, ..., Brenner H, ..., Dieffenbach AK, Stegmaier C, Arndt V, ..., Slager S, Vachon CM, Couch FJ. Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade. Human Molecular Genetics (in press).

von Winterfeld M, Hoffmeister M, Ingold-Heppner B, Jansen L, Tao S, Herpel E, Schirmacher P, Dietel M, Chang-Claude J, Autschbach F, Brenner H, Bläker H. Frequency of therapy-relevant staging shifts in colorectal cancer through the introduction of pN1c in the 7th TNM edition. European Journal of Cancer (in press).

Bock JO, Heider D, Matschinger H, Brenner H, Saum KU, Haefeli WE, König HH. Willingness to pay for health insurance among the elderly population in Germany. European Journal of Health Economics (in press).

Chen XZ, Chen H, Castro FA, Hu JK, Brenner H. Epstein-Barr virus infection and gastric cancer - a systematic review. Medicine (in press).

Hollestelle A, van der Baan F, Berchuck A, Johnatty SE, Aben KK, Agnarsson BA, ..., Arndt V, ..., Brenner H, ..., Pharoah PDP, Rookus MA, Hooning MJ, Goode EL. No clinical utility of KRAS Variant rs61764370 for ovarian or breast cancer. Gynecologic Oncology (in press).

Boehlen F, Herzog W, Maatouk I, Saum K-U, Brenner H, Wild B. Behandlungswünsche von älteren Menschen mit psychischen Erkrankungen. Zeitschrift für Gerontologie und Geriatrie (in press).

Pulte D, Jansen L, Castro FA, Emrich K, Katalinic A, Holleczek B, Brenner H, for the GEKID Cancer Survival Working Group. Trends in survival of multiple myeloma patients in Germany and in the United States in the first decade of the 21st century. British Journal of Haematology (in press).

Ordonez-Mena JM, Schöttker B, Fedirko V, Jenab M, Olsen A, Halkjær J, Kampman E, de Groot L, Jansen E, BAs Bueno-de-Mesquita H, Peeters PH, siganos G, Wilsgaard T, Perna L, Holleczek B, Pettersson-Kymmer U, Orfanos P, Trichopoulou A, Boffetta P, Brenner H. Pre-diagnostic vitamin D concentrations and cancer risks in older individuals: an analysis of cohorts participating in the CHANCES consortium. European Journal of Epidemiology (in press).

Jiao S, Peters U, Berndt S, Bézieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Lemire M, Newcomb PA, Potter JD; Slattery ML, Woods MO, Hsu L. Powerful set-based gene-environment interaction testing framework for complex diseases. Genetic Epidemiology (in press).

Zhang B, Shu XO, Delahanty RJ, Zeng C, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Hunter DJ, Easton DF, Zheng W. Height and breast cancer risk: Evidence from prospective studies and mendelian randomization. Journal of the National Cancer Institute (in press).

Lüthgens K, Albert S, Brenner H. Unterschiedliche Nachweisgrenzen immunologischer Tests auf Blut im Stuhl unterstreichen die Notwendigkeit der Standardisierung und Qualitätssicherung. Zeitschrift für Gastroenterologie (in press).

Hajek A, Bock J-O, Brenner H, Saum K-U, Matschinger H, Haefeli WE, Quinzler R, Heider D, König H-H. Welche Faktoren beeinflussen die privaten Zuzahlungen zu Gesundheitsleistungen im Alter? Ergebnisse einer Längsschnittstudie. Das Gesundheitswesen (in press).

Brenner H, Jansen L. Timely disclosure of progress in long-term cancer survival: The boomerang method substantially improved estimates in a comparative study. Journal of Clinical Epidemiology (in press).

Meeks HD, Song H, Michailidou K, Bolla MK, Dennis J, ..., Brenner H, Butterbach K, ..., Couch FJ, Spurdle AB, Goldgar DE. BRCA2 polymorphic stop codon K3326X and the risk of breast, prostate and ovarian cancers. Journal of the National Cancer Institute (in press).

Eberle A, Jansen L, Krilaviciute A, Luttmann S, Emrich K, Holleczek B, Nennecke A, Katalinic A, Brenner H, for the GEKID Cancer Survival Working Group. Lung cancer survival in Germany: a population-based analysis of 132,612 lung cancer patients. Lung Cancer (in press).

Benner A, Hoffmeister M, Jansen L, Yang R, Bläker H, Herpel E, Ulrich A, Ulrich CM, Chang-Claude J, Brenner H, Burwinkel B. Methylation status at HYAL2 predicts overall and progression-free survival of colon cancer patients under 5-FU chemotherapy. Genomics (in press).

Holleczek B, Brenner H. Implications from under-reporting, death certificate notifications and trace-back on the recorded incidence of a newly established population-based cancer registry. Methods of Information in Medicine (in press).

Brück K, Stel VS, Gambaro G, Hallan S, Völzke H, Ärnlöv J, Kastarinen M, Guessous I, Vinhas J, Stengel B, Brenner H, Chudek J, Romundstad S, Tomson C, Gonzalez AO, Bello AK, Ferrieres J, Palmieri L, Browne G, Capuano V, Van Biesen W, Zoccali C, Gansevoort R, Navis G, Rothenbacher D, Ferraro PM, Nitsch D, Wanner C, Jager KJ. Chronic kidney disease prevalence varies across European general population. Journal of the American Society of Nephrology (in press).

Werner S, Krause F, Rolny V, Strobl M, Morgenstern D, Datz C, Chen H, Brenner H. Evaluation of a 5-marker blood test for colorectal cancer early detection in a colorectal cancer screening setting. Clinical Cancer Research (in press).

Teumer A, Tin A, Sorice R, Gorski M, Yeo NC, ..., Dieffenbach AK, ..., Brenner H, ..., Butterbach K, ..., Böger CA, Fox CS, Pattaro C, Köttgen A. Genome-wide association studies identify genetic loci associated with albuminuria in diabetes. Diabetes (in press).

Sirri E, Castro F, Kieschke J, Jansen L, Emrich K, Gondos A, Holleczek B, Katalinic A, Urbschat I, Vohmann C, Brenner H for the GEKID Cancer Survival Group. Recent trends in survival of patients with pancreas cancer in Germany and the United States. Pancreas (in press).

Garcia-De-Albeniz X, Rudolph A, Hutter C, White E, Lin Y, ..., Brenner H, ..., Hoffmeister M, Butterbach K, ..., Hsu L, Chan A, Peters U, Chang-Claude J. CYP24A1 variant modifies the association between use of estrogen plus progestogen therapy and colorectal cancer. British Journal of Cancer (in press).

Eisemann N, Jansen L, Castro FA, Chen T, Eberle A, Nennecke A, Zeissig SR, Brenner H, Katalinic A, for the GEKID Cancer Survival Working Group. Survival from non-melanoma skin cancer in Germany. British Journal of Dermatology (in press).

O'Doherty MG, Cairns K, O'Neill V, Lamrock F, Jørgensen T, Brenner H, Schöttker B, Wilsgaard T, Siganos G, Kuulasmaa K, Boffetta P, Trichopoulou A, Kee F, on behalf of the CHANCES consortium. Effect of major lifestyle risk factors, independent and jointly, on life expectancy with and without cardiovascular disease: results from the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES). European Journal of Epidemiology (in press).

Easton DF, Lesueur F, Decker B, Michailidou K, Li J, ..., Arndt V, ..., Brenner H, ..., Le Calvez-Kelm F, Goldgar DE, Tavtigian SV, Chenevix-Trenche G. No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing. Journal of Medical Genetics (in press).

Zwink N, Stock C, Birkner B, Hoffmeister M, Brenner H. Screening colonoscopy volume and detection of colorectal neoplasms: A state-wide study from Bavaria, Germany. European Journal of Cancer Prevention (in press).

Kap EJ, Seibold P, Scherer D, Habermann N, Balavarca Y, Jansen L, Zucknick M, Becker N, Hoffmeister M, Ulrich A, Benner A, Ulrich CM, Burwinkel B, Brenner H, Chang-Claude J. SNPs in transporter and metabolizing genes as predictive markers for oxaliplatin treatment in colorectal cancer patients. International Journal of Cancer (in press).

Gondos A, Jansen L, Heil J, Schneeweiss A, Voogd AC, Frisell J, Fredriksson I, Johannsson U, Tvedskof TF, Jensen MB, Balslev E, Hartmann-Johnsen OJ, Sant M, Baili P, Agresti R, van de Velde T, Broeks A, Nogaret JM, Bourgois P, Moreau M, Mátrai Z, Sávolt A, Nagy P, Kásler M, Schrotz-King P, Ulrich C, Brenner H. Time trends in axilla management among early breast cancer patients: persisting major variation in clinical practice across European centers. Acta Oncologica (in press).

Petridis C, Brook MN, Shah V, Kohut K, Gorman P, ..., Brenner H, Arndt V, ..., Tomlinson I, Roylance R, Garcia-Closas M, Sawyer EJ. Genetic predisposition to ductal carcinoma in situ of the breast. Breast Cancer Research (in press).

Dumstrei K, Chen H, Brenner H. A systematic review of serum autoantibodies as biomarkers for pancreatic cancer detection. Oncotarget (in press).

Brenner H, Schrotz-King P, Holleczek B, Katalinic A, Hoffmeister M. Rückgang der Darmkrebs-Inzidenz und -Mortalität in Deutschland in den ersten 10 Jahren nach Einführung der Vorsorge Koloskopie. Deutsches Ärzteblatt (in press).

Zhang Y, Florath I, Saum KU, Brenner H. Self-reported smoking, serum cotinine, and blood DNA methylation. Environmental Research (in press).

Gdynia G, Sauer SW, Kopitz J, Fuchs D, Duglova K, Ruppert T, Miller M, Pahl J, Cerwenka A, Enders M, Mairlbäurl H, Kaminski MM, Penzel R, Zhang C, Fuller JC, Wade R Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth W. The HMGB1 protein induces a metabolic type of tumor cell death by blocking aerobic respiration. Nature Communication (in press).

Florath I, Schöttker B, Butterbach K, Bewerunge-Hudler M, Brenner H. Epigenome-wide search for association of serum 25-hydroxyvitamin D concentration with leukocyte DNA methylation in a large cohort of older men. Epigenomics (in press).

Chen H, Knebel P, Brenner H. Empirical evaluation demonstrated importance of validating biomarkers for early detection of cancer in screening settings to limit the number of false positive findings. Journal of Clinical Epidemiology (in press).

Schöttker B, Rathmann W, Herder C, Thorand B, Wilsgaard T, Njølstad I, Siganos G, Mathiesen EB, Saum KU, Peasey A, Feskens E, Boffetta P, Trichopoulou A, Kuulasmaa KK, Kee F, Brenner H. HbA1c levels in non-diabetic older adults - No J-shaped associations with primary cardovascular events, cardiovascular and all-cause mortality after adjustment for confounders. A meta-analysis of individual participant data from six cohort studies. BMC Medicine (in press).

Lin W-Y, Camp NJ, Ghoussaini M, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Dunning A, Easton DF, Cox A. Identification and characterisation of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. Human Molecular Genetics 2015; 24:285-298.

Campa D, Martino A, Varkonyi J, Lesueur F, Jamrozial K, Landi S, Jurczyszyn  A, Marques H, Andersen V, Jurado M, Brenner H, Petrini M, Vogel U, Garcia-Sanz R, Buda G, Gemignani F, Rios R, Vangsted AJ, Dumontet C, Martinez-Lopez J, Moreno MJ, Stepien A, Watek M, Moreno V, Dieffenbach AK, Rossi AM, Butterbach K, Jacobsen SEH, Goldschmidt H, Sainz J, Hillengass J, Orciuolo E, Dudzinski M, Weinhold N, Reis RM, Canzian F. Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length. International Journal of Cancer 2015:136:E351-E358.

Conway DI, Brenner DR, McMahon AD, Macpherson LMD, Agudo A, Ahrens W, Bosetti C, Brenner H, ..., Müller H, ..., Lee YCA, Hashibe M, Brennan P. Estimating and explaining the effect of education and income on head and neck cancer risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries.International Journal of Cancer 2015; 136:1125-1139.

Elgizouli M, Logan C, Nieters A, Brenner H, Rothenbacher D. Cord blood PRF1 methylation patterns and risk of lower respiratory tract infections in infants: findings from the Ulm Birth Cohort. Medicine 2015; 94:e332.

Glubb DM, Maranian MJ, Michailidou K, Pooley KA, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, .., Dunning AM, French JD. Fine scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. American Journal of Human Genetics 2015; 96:5-20.

Carvajal-Carmona L, O'Mara TA, Painter JN, ..., Brenner H, Dieffenbach AK, ..., Easton DF, Spurdle AB, Thompson DJ. Candidate locus analysis of the TERT-CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk. Human Genetics 2015; 134:231-245.

Rudolph A, Milne RL, Truong T, ..., Dieffenbach AK, Arndt V, Stegmaier C, ..., Brenner H, ..., Pharoah PDP, Garcia-Closas M, Chang-Claude J. Investigation of gene-environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors. International Journal of Cancer 2015; 136:E685-E696.

GBD 2013 Mortality and Causes of Death Collaborators*. Global, regional and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015; 385:117-171. *Collaborators from DKFZ: Brenner H, Schöttker B.

Brenner H, Hoffmeister M, Birkner B, Stock C. Which adenomas are detected by fecal occult blood testing? A state-wide analysis from Bavaria, Germany. International Journal of Cancer 2015; 136:1672-1679.

Ashwin N, Ananthakrishnan AN, Du M, Berndt SI, Brenner H, Caan BJ, Casey G, Chang-Claude J, Duggan D, Fuchs CS, Gallinger S, Giovannucci EL, Harrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hou L, Hsu L, Jenkins MA, Kraft P, Ma J, Nan H, Newcomb PA, Ogino S, Potter JD, Seminara D, Slattery ML, Thornquist M, White E, Wu K, Peters U, Chan AT. Red meat intake, NAT2, and risk of colorectal cancer: A pooled analysis of 11 studies. Cancer Epidemiology, Biomarkers and Prevention 2015; 24:198-205.

Dallmeier D, Pencina MJ, Rajman I, Koenig W, Rothenbacher D, Brenner H. Serial measurements of N-Terminal Pro-Brain Natriuretic Peptide in patients with coronary heart disease. PLoS One 2015; 10:e0117143.

Braig S, Brandt S, Wabitsch M, Florath I, Brenner H, Rothenbacher D, Genuneit J. Age-specific influence of wheezing phenotypes on preadolescent and adolescent health-related quality of life. Pediatric Allergy and Immunology 2015; 25:781-787.

Stock C, Uhlmann L, Hoffmeister M, Laux G, Kieser M, Brenner H. Identification of physicians with unusual performance in screening colonoscopy databases: a Bayesian approach. Gastrointestinal Endoscopy 2015; 81:646-654.

Kabisch M, Lorenzo Bermejo J, Dünnebier T, Ying S, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Hamann U. Inherited variants in the inner contromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER negative breast cancer. Carcinogenesis 2015; 36:256-271.

Painter JN, O'Mara TA, Batra J, ..., Brenner H, Dieffenbach AK, ..., Edwards SL, Thompson DJ, Spurdle AB. Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk. Human Molecular Genetics 2015; 24:1478-1492.

Yang R, Pfütze K, Zucknick M, Sutter C, Wappenschmidt B, Marma F, Qu B, Cuk K, Engel C, Schott S, Schneeweiss A, Brenner H, Claus R, Plass C, Bugert P, Hoth M, Sohn C, Schmutzler R, Bartram CR, Burwinkel B. DNA methylation array analyses identified breast cancer associated HYAL2 methylation in peripheral blood. International Journal of Cancer 2015; 136:1845-1855.

Bläker H, Hildebrandt B, Riess H, von Winterfeld M, Ingold-Heppner B, Roth W, Kloor M, Schirmacher P, Dietel M, Tao S, Jansen L, Chang-Claude J, Ulrich A, Brenner H, Hoffmeister M. Lymph node count and prognosis in colorectal cancer: the influence of examination quality. International Journal of Cancer 2015; 136:1957-1966.

Bickeböller M, Tagscherer K, Kloor M, Jansen L, Chang-Claude J, Brenner H, Hoffmeister M, Toth C, Schirmacher P, Roth W, Bläker H. Functional characterization of the tumor suppressor MARCKS in colorectal cancer and its association with survival. Oncogene 2015; 34:1150-1159.

Bozorgmehr K, San Sebastian M, Brenner H, Razum O, Maier W, Saum KU, Holleczek B, Miksch A, Szecsenyi J. Analysing horizontal equity in enrolment in Disease Management Programmes for coronary heart disease in Germany 2008 - 2010. International Journal for Equity in Health 2015; 14:28.

Jansen L, Castro F, Gondos A, Krilaviciute A, Barnes B, Eberle A, Emrich K, Hentschel S, Holleczek B, Katalinic A, Brenner H for the GEKID Cancer Survival Workgroup. Recent cancer survival in Germany: an analysis of common and less common cancers. International Journal of Cancer 2015; 136:2649-2658.

Allemani C, Weir HK, ..., Tucker TC, Coleman MP, Concord Working Group*. Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,877 patients from 279 population-based registries in 67 countries (CONCORD-2). The Lancet 2015; 385:977-1010. *Member of the CONCORD Working Group from DKFZ: Brenner H.

Heiss JA, Brenner H. Between-array normalization for 450K data. Frontiers in Genetics 2015; 6:92.

Brandt S, Moß A, Koenig W, Rothenbacher D, Brenner H, Wabitsch M. Intrafamilial  associations of cardiometabolic risk factors - results of the Ulm Birth Cohort Study. Atherosclerosis 2015; 240:174-183.

Nan H, Hutter CM, Lin Y, Jacobs EJ, Ulrich CM, White E, Baron JA, Berndt SI, Brenner H, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Casey G, Chang-Claude J, Chanock SJ, Cotterchio M, Duggan D, Figueiredo JC, Fuchs CS, Giovannucci EL, Gong J, Haile RW, haarrison TA, Hayes RB, Hoffmeister M, Hopper JL, Hudson TJ, Jenkins MA, Jiao S, Lindor NM, Lemire M, Le Marchand L, Newcomb PA, Ogino S, Pflugeisen BM, Potter JD, Qu C, Rosse SA, Rudolph A, Schoen RE, Schumacher FR, Seminara D, Slattery ML, Thibodeau SN, Thomas F, Thornquist M, Warnick GS, Zanke BW, Gauderman J, Peters U Hsu L, Chan AT; for the CCFR and GECCO. Association of Aspirin and NSAID use with risk of colorectal cancer according genetic variants. JAMA 2015; 313:1133-1142.

Michailidou K, Beesley J, Lindstrom S, Canisius S, ..., Brenner H, Dieffenbach AK, Arndt V, Stegmaier C, ..., Hall P, Easton DF. Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. Nature Genetics 2015; 47:373-381.

Stegeman S, Amankwah E, Klein K, O'Mara TA, Kim D, Lin HY, Permuth-Wey J, Sellers TA, Srinivasan S, Eeles R, Easton D, Kote-Jarai Z, Amin Al Olama A, Benlloch S, Muir K, Giles GG, Wiklund F, Gronberg H, Haiman CA, Schleutker J, Nordestgaard BG, Travis RC, Neal D, Pharoah P, Khaw KT, Standford JL, Blot WJ, Thibodeau S, Maier C, Kibel AS, Cybulski C, Cannon-Albright L, Brenner H, Kaneva R, Teixeria MR, Consortium P, Bioresource AP, Spurdle AB, Clements JA, Park JY, Batra J. A large scale analysis of genetic variants within putative miRNA binding sites in prostate cancer. Cancer Discovery 2015; 5:368-379.

Brenner H, Altenhofen L, Stock C, Hoffmeister M. Prevention, early detection, and overdiagnosis of colorectal cancer within 10 years of screening colonoscopy in Germany. Clinical Gastroenterology and Hepatology 2015; 13:717-723.

Emrich IE, Pickering J, Schöttker B, Lennartz CS, Rogacev KS, Brenner H, Rothenbacher D, Holleczek B, Saum KU, Fliser D, Heine GH. Comparison of the performance of two GFR Estimating Equations using creatinine and cystatin C to predict adverse outcomes in elderly individuals. Americal Journal of Kidney Diseases 2015; 65:632-638.

Schöttker B, Saum KU, Jansen EHJM, Boffetta P, Trichopoulou A, Holleczek B, Dieffenbach AK, Brenner H. Oxidative stress markers and all-cause mortality at older age. A population-based cohort study. Journal of Gerontology: Medical Sciences 2015; 70:518-524.

Schmidt ME, Chang-Claude J, Seibold P, Vrieling A, Heinz J, Flesch-Janys D, Steindorf K: Determinants of long-term fatigue in breast cancer survivors: results of a prospective patient cohort study. Psychooncology 2015; 24(1): 40-6.

Scharhag-Rosenberger F, Kuehl R, Klassen O, Schommer K, Schmidt ME, Ulrich CM, Wiskemann J, Steindorf K: Exercise training intensity prescription in breast cancer survivors: validity of current practice and specific recommendations. Journal of Cancer Survivorship 2015; 137(2):471-80.

Scharhag-Rosenberger F, Wiskemann J, Scharhag J: Cardiopulmonary exercise testing in cancer patients: should we really refrain from considering it for preparticipation screening? Oncologist 2015; 20(2): 228.

Ungar N, Sieverding M, Ulrich CM, Wiskemann J (2015): What explains the intention to be physically active in cancer patients? Different determinants for active and insufficiently active patients. J Psychosoc Oncol. 33(1):15-33.

Werner S, Chen H, Tao S, Brenner H. Systematic Review: Serum autoantibodies in the early detection of gastric cancer. International Journal of Cancer 2015; 136:2243-2252.

Rothenbacher D, Jaensch A, Mons U, Hahmann H, Becker T, Koenig W, Brenner H. Prognostic value of one-year course of symptoms of anxiety and depression in patients with coronary heart disease: role of physical activity and unmet medical need. European Journal of Preventive Cardiology 2015; 22:1129-1138.

Chen H, Chen XZ, Waterboer T, Castro FA, Brenner H. Viral infections and colorectal cancer: a systematic review of epidemiological studies. International Journal of Cancer 2015; 137:12-24.

Vart P, Bakker SJL, Schöttker B, de Zeeuw D, Rothenbacher D, Brenner H, Lambers Heerspink HJ, Saum KU, Reijneveld SA, Bültmann U, Koenig W, Gansevoort RT. Relevance of correction for drift and day-to-day variation in cystatin C measurement: a post-hoc analysis of the PREVEND cohort, with independent replication in the ESTHER cohort. Clinical Chemistry and Laboratory Medicine 2015; 53:1381-1390.

Perna L, Wahl HW, Mons U, Saum KU, Holleczek B, Brenner H. Cognitive impairment, all-cause and cause-specific mortality among non-demented older adults. Age and Ageing 2015; 44:445-451.

Boehlen F, Herzog W, Quinzler R, Haefeli WE, Maatouk I, Niehoff D, Saum KU, Brenner H, Wild B. Loneliness in the elderly is associated with the use of psychotropic drugs. International Journal of Geriatric Psychiatry 2015; 30:957-964.

Song M, Gong J, Giovannucci EL, ..., Brenner H, Chang-Claude J, ..., Hoffmeister M, ..., Jensen M, Peters U, Chan AT. Genetic variants of adiponectin and risk of colorectal cancer. International Journal of Cancer 2015; 137:154-164.

Orr N, Dudbridge F, Dryden N, ..., Brenner H, Dieffenbach AK, Arndt V, ..., dos Santos Silva I, Fletcher O, Peto J. Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2. Human Molecular Genetics 2015; 24:2966-2984.

Benetou V, Orfanos P, Feskanich D, Michaelsson K, Pettersson-Kymmer U, Ahmed L, Peasey A, Wolk A, Brenner H, Bobak M, Wilsgaard T, Schöttker B, Saum KU, Bellavia A, Grodstein F, Klinaki E, Valanou E, Papatesta HM, Boffetta P, Trichopoulou A. Education, marital status and risk of hip fractures in older men and women: the CHANCES project. Osteoporosis International 2015; 26:1733-1746.

Kap EJ, Seibold P, Richter S, Scherer D, Habermann N, Balavarca Y, Jansen L, Becker N, Pfuetze K, Popanda O, Hoffmeister M, Ulrich A, Benner H, Ulrich CM, Burwinkel B, Brenner H, Chang-Claude J. Genetic variants in DNA repair genes as potential predictive markers for oxaliplatin chemotherapy in colorectal cancer. The Pharmacogenomics Journal 2015; 15:505-512.

Mons U, Müezzinler A, Gellert C, Schöttker B, Abnet CC, Bobak M, de Groot L, Freedman ND, Jansen E, Kee F, Kromhout D, Kuulasmaa K, Laatikainen T, O'Doherty MG, Bueno-de-Mesquita B, Orfanos P, Peters A, van der Schouw YT, Wilsgaard T, Wolk A, Trichopoulou A, Bofetta P, Brenner H, on behalf of the CHANCES consortium. Impact of smoking and smoking cessation on cardiovascular events and mortality among older adults - Meta-analysis of individual participant data from prospective cohort studies of the CHANCES consortium. British Medical Journal 2015; 350:h1551.

Hsu L, Jeon J, Brenner H, Gruber SB, Schoen RE, Berndt SI, Chan AT, Chang-Claude J, Du M, Gong J, Harrison TA, Hayes RB, Hoffmeister M, Hutter CM, Lin Y, Nishihara R, Ogino S, Prentice RL, Schumacher FR, Seminara D, Slattery ML, Thomas DC, Thornquist M, Newcomb PA, Potter JD, Zheng Y, White E, Peters U on behalf of the Colorecal Transdisciplinary (CORECT) Study and Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO). A model to determine colorectal cancer risk using common genetic susceptibility loci. Gastroenterology 2015; 148:1330-1339.

Hoffmeister M, Jansen L, Rudolph A, Toth C, Kloor M, Roth W, Bläker H, Chang-Claude J, Brenner H. Statin use and survival after colorectal cancer: the importance of comprehensive confounder adjustment. Journal of the National Cancer Institute 2015; 107:djv045.

Saum KU, Dieffenbach AK, Jansen EHJM, Schöttker B, Holleczek B, Hauer K, Brenner H. Association between oxidative stress and frailty in an elderly German population: results from the ESTHER cohort study. Gerontology 2015; 61:407-415.

Pulte D, Jansen L, Brenner H. Survival disparities by insurance type for patients age 15-64 with Non-Hodgekin Lymphoma. The Oncologist 2015; 20:554-561.

Walter V, Jansen L, Hoffmeister M, Ulrich A, Chang-Claude J, Brenner H. Smoking and survival of colorectal cancer patients: population-based study from Germany. International Journal of Cancer 2015; 137:1433-1445.

Brenner H, Jansen L. Restriction to period of interest improves informative value of death certificate only proportions in period analysis of cancer survival. Journal of Clinical Epidemiology 2015; 68:1432-1439.

Zhang Y, Schöttker B, Ordonez-Mena J, Holleczek B, Yang R, Burwinkel B, Butterbach K, Brenner H. F2RL3 methylation, lung cancer incident and mortality. International Journal of Cancer 2015; 137:1739-1748.

Guo Q, Schmidt MK, Kraft P, Canisius S, ..., Brenner H, Dieffenbach AK, Arndt V, ..., Pharoah PDP. Identification of novel genetic markers of breast cancer survival. Journal of the National Cancer Institute 2015; 107:djv081.

Müezzinler A, Gellert C, Mons U, Schöttker B, Jansen E, Kee F, O'Doherty MG, Kuulasmaa K, Freedman ND, Abnet CC, Wolk A Håkansson N, Orsini N, Wilsgaard T, Njølstad I, Bøgeberg M, Leenders M, Bueno-de-Mesquita B, van der Schouw YT, Peeters PH, Streppel MT, de Groot LCPGM, Peters A, Schneider A, Orfanos P, Linneberg A, Pisinger C, Lorbeer R, Tamosiunas A, Baceviciene M, Luksiene D, Bernotiene G, Jousilahti P, Schaan B, Wennberg P, Petterson-Kymmer U, Jansson JH, Söderberg S, Eriksson S, jankovic N, Kromhout D, Geelen A, Sánchez M-J, Veronesi G, Trichopoulou A, Boffetta P, Brenner H. Smoking and all-cause mortality in older adults - Results from CHANCES Consortium. American Journal of Preventive Medicine 2015; 49:e53-e63.

Campa D, Rizzato C, Stolzenberg-Solomon R, Pacetti P, Vodicka P, Cleary S, Capurso G, Bas Bueno-de-Mesquita H, Werner J, Gazouli M, Butterbach K, Ivanauskas A, Giese N, Petersen GM, Fogar P, Wang Z, Bassi C, Ryska M, Theodoropoulos GE, Kooperberg C, Hassan M, Greenhalf W, Pasquali C, Hackert T, Fuchs C, Mohelníková-Duchoñová B, Sperti C, Funel N, Dieffenbach AK, Wareham NJ, Buring J, Holcátová I, Costello-Goldring E, Zambone C-F, Kupcinskas J, Risch HA, Kraft P, Bracci PM, Pezzilli R, Olson SH, Sesso H, Hartge P, Strobel O, Malecka-Panas E, Visvanathan K, Arslan AA, Pedrazzoli S, Sucek P, Gioffreda D, Key TJ, Talar-Wojnarowska R, Scarpa A, Mambrini A, Jacobs EJ, Jamroziak K, Klein A, Tavano F, Bambi F, Landi S, Austin MA, Vodickova L, Brenner H, Chanock SJ, Delle Fave G, Piepoli A, Cantore M, Zheng W, Wolpin B, Amundadottir L, Canzian F. The TERT gene harbors multiple variants associated with pancreatic cancer susceptibility. International Journal of Cancer 2015; 137:2175-2183.

Chen H, Zucknick M, Werner S, Brenner H. Head-to head comparison and evaluation of 92 plasma protein biomarkers for early detection of colorectal cancer in a true screening setting. Clinical Cancer Research 2015; 21:3318-3326.

Brenner H, Altenhofen L, Stock C, Hoffmeister M. Expected long-term impact of the German screening colonoscopy program on colorectal cancer prevention: analyses based on 4,407,971 screening colonoscopies. European Journal of Cancer 2015; 51:1346-1353.

Chen XZ, Chen H, Castro FA, Hu JK, Brenner H. Epstein-Barr virus infection and gastric cancer - a systematic review. Medicine 2015; 94(20):e792.

Al Olama AA, Benlloch S, Antoniou AC, Giles GG, Severi G, Neal D, Hamdy FC, Donovan JL, Muir K, Schleutker J, Henderson BE, Haiman C, Schumacher FR, Pashayan N, Pharoah PD, Ostrander EA, Stanford JL, Batra J, Clements JA, Chambers SK, Weischer M, Nordestgaard BG, Ingles SA, Sorensen KD, Orntoft TF, Park JY, Cybulski C, Maier C, Doerk T, Dickinson JL, Cannon-Albright L, Brenner H, Rebbeck TR, Zeigler -Johnson C, Habuchi T, Thibodeau SN, Cooney K, Chappius PO, Hutter P, Kaneva RP, Foulkes WD, Zeegers MP, Lu YJ, Zhang HW, Stephenson R, Cox A, Southey MC, Spurdle AB, FitzGerald L, Leongamornlert D, Saunders E, Tymrakiewicz M, Guy M, Dadaev T, Little SJ, Govindasami K, Sawyer E Wilkinson R, Herkommer K, Hopper JL, Lophatonanon A, Rinckleb AE, Kote-Jarai Z, Eeles RA, Easton DF. Risk analysis of prostate cancer in PRACTICAL, a multinational consortium, using 25 unknown prostate cancer susceptibility loci. Cancer Epidemiology, Biomarkers and Prevention 2015; 24:1121-1129.

Darabi H, McCue K, Beesley J, Michailidou K, ..., Brenner H, ..., Arndt V, ..., Dunning AM, Easton DF, Hall P, Cevenix-Trench G. Polymorphisms in a putative enhancer at the 10q21.2 breast cancer risk locus regulate NRBF2 expression. American Journal of Human Genetics 2015; 97:22-34.

Schumacher F, Schmit S, Jiao S, Edlund C, Wang H, ..., Butterbach K, ..., Brenner H, ... Hoffmeister M, ..., Casey G, Gruber S, Peters U. Genome-wide association study of colorectal cancer identifies six new susceptibility loci. Nature Communication 2015; 6:7138.

Pirie A, Guo Q, Kraft P, Canisius S, Eccles DM, ..., Brenner H, Butterbach K, Arndt V, ..., Fasching PA, Pharoah PDP, Schmidt MK. Common germline polymorphisms associated with breast cancer specific survival. Breast Cancer Research 2015; 17:58.

Global Burden of Disease Study 2013 Collaborators*. Global, regional, and national incidence, prevalence, and YLDs for 301 acute and chronic diseases and injuries for 188 countries, 1990-2013: a systematic analysis for the Global Burden of Diseases Study 2013. The Lancet 2015; 386:743-800. *Collaborators from DKFZ: Brenner H, Schöttker B.

Brenner H, Altenhofen L, Kretschmann J, Rösch T, Pox C, Stock C, Hoffmeister M. Trends in adenoma detection rates during the first 10 years of the German screening colonoscopy program. Gastroenterology 2015; 149:356-366.

Kahlert C, Lerbs T, Pecqueux M, Herpel E, Hoffmeister M, Jansen L, Brenner H, Chang-Claude J, Bläker H, Kloor M, Roth W, Pilarsky C, Rahbari NN, Schölch S, Bork U, Reissfelder C, Weitz J, Aust D, Koch M. Overexpression of SIX1 is an independent prognostic marker in stage I - III colorectal cancer. International Journal of Cancer 2015; 137:2104-2113.

Beyerle J, Frei E, Stiborova M, Habermann N, Ulrich CM. Biotransformation of xenobiotics in the human colon and rectum and its associations with colorectal cancer. Drug Metab Rev 2015; 47(2):199-221.

Wiskemann J, Kleindienst N, Kuehl R, Dreger P, Schwerdtfeger R, Huber G, Bohus M. Effects of a physical exercise on survival after allogeneic stem cell transplantation. International Journal of Cancer 2015; 137(11):2749-56.

Schmidt ME, Wiskemann J, Armbrust P, Schneeweiss A, Ulrich CM, Steindorf K: Effects of resistance exercise on fatigue and quality of life in breast cancer patients undergoing adjuvant chemotherapy: A randomized controlled trial. International Journal of Cancer 2015; 137(2), 471-480.

Gollhofer SM, Wiskemann J, Schmidt ME, Klassen O, Ulrich CM, Oelmann J, Hof H, Potthoff K, Steindorf K (2015): Factors influencing participation in a randomized controlled resistance exercise intervention study in breast cancer patients during radiotherapy. BMC Cancer, 15(1):186.

Skender S, Schrotz-King P, Böhm J, Abbenhardt C, Gigic B, Chang-Claude, J, Siegel EM, Steindorf, K, Ulrich, CM. Repeat physical activity measurement by accelerometry among colorectal cancer patients—feasibility and minimal number of days of monitoring. BMC Research Notes 2015; 8:222.

Kharazmi E, Fallah M, Pukkala E, Olsen JH, Tryggvadottir L, Sundquist K, Tretli S, Hemminki K. Risk of familial classical Hodgkin lymphoma by relationship, histology, age, and sex: a joint study from five Nordic countries. Blood 2015; 126(17): 1990-5.

Kharazmi E, Hemminki K, Pukkala E, Sundquist K, Tryggvadottir L, Tretli S, Olsen JH, Fallah M. Cancer Risk in Relatives of Testicular Cancer Patients by Histology Type and Age at Diagnosis: A Joint Study from Five Nordic Countries. Eur Urol 2015; 68(2):283-9.

Frank C, Fallah M, Sundquist J, Hemminki A, Hemminki K. Population Landscape of Familial Cancer. Sci Rep 2015; 5:12891.

Chen T, Fallah M, Jansen L, Castro FA, Krilaviciute A, Katalinic A, Emrich K, Holleczek B, Geiss K, Eberle A, Sundquist J, Brenner H, Hemminki H, for the GEKID Cancer Survival Working Group. Distribution and risk of the second discordant primary cancers combined after a specific first primary cancer in German and Swedish cancer registries. Cancer Letters 2015; 369:152-166.

Brenner H. Colorectal cancer screening for older adults. BMJ 2015; 350:h2029.

Schöttker B, Brenner H. Vitamin D as a resilience factor, helpful for survival of potentially fatal conditions. A hypothesis emerging from recent findings of the ESTHER cohort study and the CHANCES consortium. Nutrients 2015; 7:3264-3278.

Sobral-Leite M, Wesseling J, Smit V, Nevanlinna H, van Miltenburg MH, ..., Brenner H, Butterbach K, Arndt V, Holleczek B, ..., García-Closas M, de Graauw M, Schmidt MK. Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis. BMC Medicine 2015; 13:156.

Darabi H, McCue K, Beesley J, Michailidou K, ..., Brenner H, ..., Arndt V, ..., Dunning AM, Easton DF, Hall P, Cevenix-Trench G. Polymorphisms in a putative enhancer at the 10q21.2 breast cancer risk locus regulate NRBF2 expression. American Journal of Human Genetics 2015; 97:22-34.

Thrift AP, Gong J, Peters U, Chang-Claude J, Rudolph A, Slattery ML, Chan AT, Locke AE, Kahali B, Justice AE, Pers TH, Gallinger S, Hayes RB, Baron JA, Caan BJ, Ogino S, Berndt SI, Chanock SJ, Casey G, Haile RW, Du M, Harrison TA, Thornquist M, Duggan DJ, Le Marchand L, Lindor NM, Seminara D, Song M, Wu K, Thibodeau SN, Cotterchio M, Win AK, Jenkins MA, Hopper JL, Ulrich CM, Potter JD, Newcomb PA, Hoffmeister M, Brenner H, White E, Hsu L, Campbell PT. Mendelian randomization study of body mass index and colorectal cancer risk. Cancer Epidemiology, Biomarkers and Prevention 2015; 24:1024-1031.

Schöttker B, Zhang Y, Heiss JA, Butterbach K, Jansen EHJM, Bewerunge-Hudler M, Saum KU, Holleczek B, Brenner H. Discovery of a novel epigenetic cancer marker related to the oxidative status of human blood. Genes Chromosomes and Cancer 2015; 54:583-594.

Gondos A, Krilaviciute A, Smailyte G, Ulys A, Brenner H. Cancer surveillance using registry data: results and recommendations for the Lithuanian national prostate cancer early detection programme. European Journal of Cancer 2015; 51:1630-1637.

Brenner H, Altenhofen L, Kretschmann J, Rösch T, Pox C, Stock C, Hoffmeister M. Trends in adenoma detection rates during the first 10 years of the German screening colonoscopy program. Gastroenterology 2015; 149:356-366.

Müezzinler A, Mons U, Dieffenbach AK, Butterbach K, Saum KU, Schick M, Stammer H, Boukamp P, Holleczek B, Stegmaier B, Brenner H. Smoking habits and leukocyte telomere length dynamics among older adults: Results from the ESTHER cohort. Experimental Gerontology 2015; 70:18-25.

Szulkin R, Whitington T, Eklund M, Aly M, Eeles RA, ..., Brenner H, Butterbach K, Stegmaier C, ..., the PRACTICAL consortium, Gronberg H, Wiklund F. Prediction of individual genetic risk to prostate cancer using a polygenic score. The Prostate 2015; 75:1467-1474.

Freigofas J, Seidling HM, Quinzler R, Schöttker B, Saum KU, Brenner H, Haefeli WE. Characteristics of medication schedules used by elderly ambulatory patients. European Journal of Clinical Pharmacology 2015; 71:1109-1120.

Childs EJ, Mocci E, Campa D, Bracci PM, Gallinger S, Goggins MG, Li D, Neale R, Olson SH, Scelo G, Bamlet WR, Bijlsma M, Blackford A, Borges M, Brennan P, Brenner H, Bueno-de-Mesquita HB, Canzian F. Capurso G, Cavestro GM, Chaffee KG, Cleary SP, Cotterchio M, Foretova L, Funel N, Gazouli M, Hassan M, Holcatova I, Holly EA, Janout V, Key TJ, Kupcinskas J, Kurtz RC Landi S, Lu L, Malecka-Panas E, Mambrini A, Mohelnikova-Duchonova B, Neoptolemos JP, Oberg AL, Orlow I, Pasquali C, Pezzilli R, Rizzato C, Saldia A, Scarpa A, Strobel O, Tavano F, Vashist YK, Vodicka P, Yu H, Petersen GM, Risch H, Klein AP. Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer. Nature Genetics 2015; 47:911-916.

Candido do Reis FJ, Lynn S, Ali HR, Eccles D, Hanby A, Provenzano E, Caldas C, Howqat WJ, McDuffus LA, Liu B, Daley F, Coulson P, Vyas RJ, Harris LM, Owens JM, Carton AFM, McQuillan JP, Paterson AM, Hirji Z, Christie SK, Holmes AR, Schmidt MK, Garcia-Closas M, Easton DF, Bolla MK, Wang Q, Benitez J, Milne RL, Mannermaa A, couch F, Defilee P, cox A, Cross SS, Blows FM, Sanders J, de Groot R, Figueroa J, Sherman M, Hooning M, Brenner H, Holleczek B, Stegmaier C, Lintott C, Pharoah PDP for the Citizen Science Alliance. Croudsourcing the general public for large scale molecular pathology studies in cancer. EBioMedicine 2015; 2:681-689.

Meid AD, Quinzler R, Feigofas J, Saum K-U, Schöttker B, Holleczek B, Heider D, König H-H, Brenner H, Haefeli WE. Medication underuse in aging outpatients with cardiovascular disease: prevalence, determinants, and outcomes in a prospective cohort study. PLoS One 2015;10:e0136339.

Surinova S, Choi M, Tao S, Schüffler PJ, Chang CY, Clough T, Vyslouzil K, Khoylou M, Srovnal J, Liu Y, Matondo M, Hüttenhain R, Weisser H, Buhmann JM, Hajdúch M, Brenner H, Vitek O, Aebersold R. Prediction of colorectal cancer diagnosis based on circulating plasma proteins. EMBO Molecular Medicine 2015; 7:1166-1178.

Surinova S, Radová L, Choi M, Srovnal J, Brenner H, Vitek O, Hajdúch M,  Aebersold R. Non-invasive prognostic protein biomarker signatures associated with colorectal cancer. EMBO Molecular Medicine 2015; 7:1153-1165.

Khalili H, Gong J, Brenner H, Austin TR, Hutter CM, Baba Y, Baron JA, Berndt SI, Bézieau S, Caan B, Campbell PT, Chang-Claude J, Chanock SJ, Chen C, Hus L, Jiao S, Conti DV, Duggan D, Fuchs CS, Gala M, Gallinger S, Haile RW, Harrison TA, Hayes R, Hazra A, Henderson B, Haiman C, Hoffmeister M, Hopper JL, Jenkins MA, Kolonel LN, Küry S, LaCroix A, le Marchand L, Lemire M, Lindor NM, Ma J, Manson JE, Morikawa T, nan H, Ng K, Newcomb PA, Nishihara R, Potter JD, Qu C, Schoen RE, Schumacher FR, Seminara D, Taverna D, Thibodeau S, Wactawski-Wende J, White E, Wu K, Zanke BW, Casey G, Hudson TJ, Kraft P, Peters U, Slattery ML, Ogino S, Chan AT on behalf of GECCO and CCFR. Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer. Carciogenesis 2015; 36:999-1007.

Chen LS, Hung RJ, Baker T, Horton A, Culverhouse R, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kin C, Lutz S, Rosenberger A, Aben KK, Andrew AS, Breslau N, Chang SC, Dieffenbach AK, Dienemann H, Frederiksen B, Han J, Hatsukami DK, Johnson EO, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden HF, Wampfler J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Duell EJ, Haugen A, Heinrich H, Hokanson JE, Hunter DJ, Kiemeney LA, Lazarus P, Le Marchand L, Liu G, Mayordomo J, Risch A, Schwartz AG, Teare D, Wu X, Wiencke JK, Yang P, Zhang ZF, Spitz MR, Kraft P, Amos CI, Bierut LJ. CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis - a meta-analysis. Journal of the National Cancer Institute 2015; 107:djv100.

Rothenbacher D, Dallmeier D, Mons U, Rosamond W, Koenig W, Brenner H. Sexual activity patterns before myocardial infarction and risk for subsequent cardiovascular adverse events. JACC 2015; 66:1516-1517.

Brenner H. Mortality from malignant melanoma in an era of nationwide skin cancer screening. Deutsches Ärzteblatt 2015; 112:627-628.

Anderson LA, Tavilla A, Brenner H, Luttmann S, Navaro C, Gavin AT, Holleczek B, Johnston BT, Cook MB, Bannon f, Sant M, EUROCARE-5 Working Group. Survival for oesophageal, stomach and small intestine cancers: results from EUROCARE-5. European Journal of Cancer 2015; 51:2144-2157.

Holleczek B, Rossi S, Domenic A, Innos K, Minicozzi P, Francisci S, Hackl M, Eisemann N, Brenner H, and the EUROCARE-5 Working Group. On-going improvement and persistent differences in the survival for patients with colon and rectum cancer across Europe - results from the EUROCARE-5 study. European Journal of Cancer 2015; 51:2158-2168.

Gao X, Jia M, Zhang Y, Breitling LP, Brenner H. DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies. Clinical Epigenetics 2015; 7:113.

Brenner H, Stock C, Hoffmeister M. Colorectal cancer screening: the time to act is now. BMC Medicine 2015; 13:262.

Bozorgmehr K, Maier W, Brenner H, Saum KU, Stock C, Miksch A, Holleczek B, Szecsenyi J, Razum O. Social disparities in Disease Management Programmes for coronary heart disease in Germany: A cross-classified multilevel analysis. Journal of Epidemiology & Community Health 2015; 69:1091-1101.

Galeone C, Turati F, Zhang ZF, Guerico V, Tavani A, Serraino D, Brennan P, Fabianova E, Lissowska J, Mates D, Rudnai P, Shangina O, Szeszenia-Dabrowska N, Vaughan TL, Kelsey K, McClean M, Levi F, Hayes RB, Purdue MP, Bosetti C, Brenner H, Pelucchi C, Lee YCA, Hashibe M, Boffetta P, La Vecchia C. Relation of allium vegetables intake with head and neck cancers: evidence from the INHANCE Consortium. Molecular Nutrition and Food Research 2015; 59:1641-1650.

Castro FA, Jansen L, Krilaviciute A, Katalinic A, Pulte D, Sirri E, Ressing M, Holleczek B, Luttmann S, Brenner H, for the GEKID Cancer Survival Working Group. Survival of patients with gastric lymphoma in Germany and the United States. Journal of Gastroenterology and Hepatology 2015; 30:1485-1491.

Perna L, Mons U, Rujescu D, Kliegel M, Brenner H. Apolipoprotein E e4 and cognitive function: a modifiable association? Results from two independent cohort studies. Dementia and Geriatric Cognitive Disorders 2015; 41:35-45.

Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, ..., Arndt V, ..., Brenner H, ..., Murabito JM, Perry JRB, Murray A. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics 2015; 47:1294-1303.

Imhof A, Koenig W, Jaensch A, Mons U, Brenner H, Rothenbacher D. Long-term prognostic value of lgM antibodies against phosphorylcholine for adverse cardiovascular events in patients with stable coronary heart disease. Atherosclerosis 2015; 243:414-420.

Lemire M, Qu C, Loo LWM, Zaidi SHE, Wang H, Berndt SI, Bézieau S, Brenner H, Campbell PT, Chan AT, Chang-Claude J, Du M, Edlund CK, Gallinger S, Haile RW, Harrision TA, Hoffmeister M, Hopper JL, Hou L, Hsu L, Jacobs EJ, Jenkins MA, Jeon J, Küry S, Li L, Lindor NM, Newcomb PA, Potter JD, Rennert G, Rudolph A, Schoen RE, Schumacher FR, Seminara D, Severi G, Slattery ML, White E, Wood MO, Cotterchio M, Le Marchand L, Casey G, Gruber SB, Peters U, Hudson TJ. A genome-wide association study for colorectal cancer identifies a risk locus in 14q23.1. Human Genetics 2015; 134:1249-1262.

Guo X, Long J, Zeng C, Michailidou K, Ghoussaini M, ..., Arndt V, ..., Brenner H, ..., Dunning AM, Easton DF, Zheng W. Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk. Cancer Epidemiology, Biomarkers & Prevention 2015; 24:1680-1691.

Brenner H, Altenhofen L, Stock C, Hoffmeister M. Vorsorge-Koloskopie in Deutschland - Bilanz und Perspektiven. Endoskopie heute 2015; 28:174-177.

Krilaviciute A, Heiss JA, Leja M, Kupcinskas J, Haick H, Brenner H. Detection of cancer through exhaled breath: a systematic review. Oncotarget 2015; 6:38643-38657.

Pfütze K, Benner A, Hoffmeister M, Jansen L, Yang R, Bläker H, Herpel E, Ulrich A, Ulrich CM, Chang-Claude J, Brenner H, Burwinkel B. Methylation status at HYAL2 predicts overall and progression-free survival of colon cancer patients under 5-FU chemotherapy. Genomics 2015; 106:348-354.

Eberle A, Jansen L, Krilaviciute A, Luttmann S, Emrich K, Holleczek B, Nennecke A, Katalinic A, Brenner H, for the GEKID Cancer Survival Working Group. Lung cancer survival in Germany: a population-based analysis of 132,612 lung cancer patients. Lung Cancer 2015; 90(3):528-533.

Haug U, Rösch T, Hoffmeister M, Katalinic A, Brenner H, Becker N. Einführung eines organisierten Darmkrebs-Screenings in Deuschland: Chancen und Herausforderungen. Das Gesundheitswesen 2015; 77(11):869-74.
 

Zeller G, Tap J, Voigt AY, Sunagawa S, Kultima JR, Costea PI, Amiot A, Böhm J, Brunetti F, Habermann N, Hercog R, Koch M, Luciani A, Mende DR, Schneider MA, Schrotz-King P, Tournigand C, Tran Van Nhieu J, Yamada T, Zimmermann J, Benes V, Kloor M, Ulrich CM, von Knebel Doeberitz M, Sobhani I, Bork P. (2014), "Potential of fecal microbiota for early-stage detection of colorectal cancer". Mol Syst Biol, 2014. 10(11): p. 766.

Liesenfeld DB, Habermann N, Toth R, Owen RW, Frei E, Böhm J, Schrotz-King P, Klika KD, Ulrich CM (2014), "Changes in urinary metabolic profiles of colorectal cancer patients enrolled in a prospective cohort study (ColoCare)". Metabolomics, 2014, Vol. 10, Nr. 6. DOI 10.1007/s11306-014-0758-3

Ristau J, Staffa J, Schrotz-King P, Gigic B, Makar KW, Hoffmeister M, Brenner H, Ulrich A, Schneider M, Ulrich CM, Habermann N. (2014), "Suitability of Circulating miRNAs as Potential Prognostic Markers in Colorectal Cancer". Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12): 2632-7. PMID: 25472670

Schmid D, Steindorf K, Leitzmann MF (2014): Epidemiologic Studies of Physical Activity and Primary Prevention of Cancer. Dt. Zeitschrift für Sportmedizin, 65, 5-10.

Klassen O, Schmidt ME, Scharhag-Rosenberger F, Sorkin M, Ulrich CM, Schneeweiss A, Potthoff K, Steindorf K*, Wiskemann J* (2014): Cardiorespiratory fitness in breast cancer patients undergoing adjuvant therapy. Acta Oncologica, 53, 1356-65. *Shared last authorship

Wiskemann J, Steindorf K (2014): Resistance training as supportive therapy in Oncology [in German]. Dt. Zeitschrift für Sportmedizin, 65, 22-24.

Wientzek A, Vigl M, Steindorf K, Brühmann B, Bergmann MM, Harttig U, Katzke V, Kaaks R, Boeing H (2014): The Improved Physical Activity Index for measuring physical activity in EPIC Germany. PLos One, 9, e92005, epub only.

Steindorf K, Schmidt ME, Wiskemann J, Ulrich CM (2014). Physiologic and molecular mechanisms linking endurance and resistance training with effects for cancer patients. Dt. Zeitschrift für Sportmedizin, 65, 299-303.

Brühmann B, Schmidt ME, Steindorf K (2014): Assessment of physical activity in epidemiological studies: Are questionnaires obsolete in the era of accelerometry? GMS Medizinische Informatik, Biometrie und Epidemiologie, 10(1). doi:10.3205/mibe000155.

Steindorf K*, Schmidt ME*, Klassen O, Ulrich CM, Oelmann J, Habermann N, Beckhove P, Owen R, Debus J, Wiskemann J, Potthoff K (2014): Randomized Controlled Trial of Resistance Training in Breast Cancer Patients Receiving Adjuvant Radiotherapy: Results on Cancer-related Fatigue and Quality of Life. Annals of Oncology, 25, 2237-43. *Shared first authorship

Scharhag-Rosenberger F, Becker T, Streckmann F, Schmidt K, Berling A, Bernardi A, Engeroff T, Exner AK, Gutekunst K, Hofmeister D, Jensen W, Kähnert H, Kneis S, Limbach M, Mau-Möller A, Röcker K, Schmidt ME, Schmidt T, Stöckel T, Wehrle A, Wiskemann J, Zimmer P, Zopf E, Steindorf K (2014). Studien zu körperlichem Training bei onkologischen Patienten: Empfehlungen zu den Erhebungsmethoden. Dt. Zeitschrift für Sportmedizin, 65, 304-313.

Steindorf K, Schmidt ME, Scharhag-Rosenberger F, Wiskemann J (2014): Supportive Sport- und Bewegungstherapie für onkologische Patienten. Onkologie Heute, 9, 41-46.

Schmidt ME, Wiskemann J, Steindorf K (2014). Exercise in breast cancer patients: impact on health. Breast Cancer Management 3:241–250.

Kuehl R, Scharhag-Rosenberger F, Schommer K, Dreger P, Bohus M, Wiskemann J (2014). Exercise intensity classification in cancer patients undergoing allogeneic HSCT. Medicine & Science in Sport and Exercise; epub ahead of print

Wiskemann J, Scharhag-Rosenberger F (2014). Nebenwirkungsorientierte Behandlungspfade für die bewegungstherapeutische Betreuung onkologischer Patienten. Bewegungstherapie und Gesundheitssport 30(4), 146-150

Huebner J, Marienfeld S, Abbenhardt C, Ulrich CM, Muenstedt K, Micke O, Muecke R., Loeser C. Counseling patients on cancer diets: a review of the literature and recommendations for clinical practice. Anticancer Research 2014;34,39-48.

Stiborová M, Frei E. Ellipticines as DNA-targeted chemotherapeutics, Current Med. Chem. 2014;21,575-591.

Wiskemann J, Steindorf K (2014). Standards der Sportmedizin: Krafttraining als Supportivtherapie bei onkologischen Patienten [Resistance training as supportive therapy for cancer patients]. Deutsche Zeitschrift für Sportmedizin, 65(1): 22-24.

Klassen O, Schmidt ME, Scharhag-Rosenberger F, Sorkin M, Ulrich CM, Schneeweiss A, Potthoff K, Steindorf K*, Wiskemann J* (2014): Cardiorespiratory fitness in breast cancer patients undergoing adjuvant therapy. Acta Oncologica, 53, 1356-65. *Shared last authorship

Wientzek A, Vigl M, Steindorf K, Brühmann B, Bergmann MM, Harttig U, Katzke V, Kaaks R, Boeing H (2014): The Improved Physical Activity Index for measuring physical activity in EPIC Germany. PLos One, 9, e92005.

Steindorf K*, Schmidt ME*, Klassen O, Ulrich CM, Oelmann J, Habermann N, Beckhove P, Owen R, Debus J, Wiskemann J, Potthoff K (2014): Randomized Controlled Trial of Resistance Training in Breast Cancer Patients Receiving Adjuvant Radiotherapy: Results on Cancer-related Fatigue and Quality of Life. Annals of Oncology, 25, 2237-43. *Shared first authorship

Brühmann, BA, Schmidt, ME, Wientzek A, Vigl M, Teucher B, Katzke VA, Boeing H, Bergmann MM, Kaaks R, Steindorf K (2014): Reliability and validity of the Questionnaire on Annual Physical Activity Pattern: A validation study using combined heart rate and accelerometry data as an objective measurement. World Journal of Epidemiology and Cancer Prevention, 3, 51-63.

1. Baumann FT, Wiskemann J (2014). Sport- und Bewegungstherapie. In: Heim R, Weis J eds. Fatigue bei Krebserkrankungen, 154-165. Stuttgart: Schattauer Verlag.
2. Baumann F, Schüle K, Leitzmann M, Steindorf K (2015): Präventionsbroschüre „Schritt für Schritt zur Bewegung“. Herausgeber Deutsche Krebshilfe und Deutsche Krebsgesellschaft, Bonn/Berlin. 74 Seiten.

1. Löser C, Arends J, , Steindorf K, Scheppach W, Staffa J, Ulrich CM, Wiskemann J, Riemann JF (2014). Prävention und Therapie von Dickdarmkrebs – Plädoyer für einen gesunden Lebensstil - Frankfurter Erklärung der Stiftung Lebensblicke.