Mine Özcan-Wahlbrink

Wissenschaftlicher Lebenslauf

   
Feb - Nov 2018 Postdoctoral scientist, Junior Research Group Immunotherapy and Immunoprevention, DKFZ, Heidelberg
2014 - 2017 PhD student, Applied Tumor Biology, DKFZ, Heidelberg
2012 - 2014 MSc Biology, Graduate School of Natural and Applied Sciences, Middle East Technical University, Ankara, Turkey
2008 - 2012 BSc Biology, Department of Biology, Middle East Technical University, Ankara, Turkey

Forschungsprojekt

Immunological causes for radiosensitivity of HPV-driven HNSCC

HPV-driven head and neck squamous cell carcinomas (HNSCCs) constitute 80% of oropharyngeal squamous cell carcinomas. They are characterized by a significant survival advantage over HPV-negative HNSCCs. In addition to better overall survival, HPV+ HNSCCs are more sensitive to irradiation than their HPV-negative counterparts. The main goal of this project was to determine if there is a link between the increased radiosensitivity of HPV-driven HNSCC and a possible elevated presentation of HPV-encoded and/or mutation-derived neoepitopes following irradiation as compared to HPV-negative HNSCCs.

Resultierende Publikationen