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Immunotherapy and Immunoprevention

Lia T. Roth

MD Student

© dkfz.de

Phone: +49 6221 42 3822

Contact

Scientific CV

Since March 2020
MD student, Immunotherapy and Immunoprevention, DKFZ, Heidelberg

Since Oct 2017
Medical student, University of Heidelberg

 

Research project

Therapeutic HPV16 vaccination – in vitro characterization and subsequent validation in a MHC-humanized tumor model

Human papillomavirus infection may cause anogenital and oropharyngeal cancer. Currently, there is no treatment on the market to support the immune system to clear established infections. Therefore, our group aims to develop a therapeutic vaccine capable of inducing a strong immune response to eliminate the infection. This project is about characterizing a new nanoparticle vaccine in vitro. Further on, the nanoparticle vaccine will be compared to the candidate lipopolyplex vaccine currently used in our group. The in vivo comparison will be done in a MHC-humanized HPV16 tumor model.

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