MARIE
MARIE and its follow-up studies
Breast cancer risk factor survey
The MARIE study is a population-based case-control study on breast cancer with more than 11,000 women. In the years 2001-2005, histologically confirmed patients with breast cancer or carcinoma in situ (age range 50-74 years) and, as controls, women without breast cancer, matched 1:2 by age and study region, were included. The study took place in the two regions of Hamburg and Rhine-Neckar-Karlsruhe. There were three follow-up studies, the last in 2020 and a mortality follow-up until 2021.
Comprehensive health-related information was collected at each survey. The patients were each asked to provide a blood sample. In addition, treatment data was collected and the recurrence of breast cancer was asked from treating physicians and clinics. The controls provided a blood sample upon recruitment. All blood samples are stored at the DKFZ.
