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Searchresult: Molecular Thoracic Oncology
Our Research Our research is focused on understanding the genetic and molecular basis of lung and breast cancers by studying various oncogenic drivers and specific genetic alterations that drive…
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Searchresult: Signal Transduction in Cancer and Metabolism
Research Synopsis When cancer cells proliferate to form a tumor, they need to grow and to divide. Regulation of cell division (i.e. the cell cycle) has been extensively studied. In comparison, the…
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Searchresult: Translational Neuroblastoma Research
Our Research Neuroblastoma (NB) is the most common pediatric single-entity solid cancer derived from primitive cells of the peripheral sympathetic nervous system. It is characterized by…
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Searchresult: Theoretical Systems Biology
Our Research Present research priorities Given that cancer-associated mutations occur continuously in renewing tissues, such as blood, these tissues are likely to have protective mechanisms in place…
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Searchresult: Brain Tumor Translational Targets
Our Research Glioblastoma stem-like cells (GSCs), which play a crucial role in tumor relapse, exhibit strong resistance to conventional chemo- and radiotherapy due to their robust self-renewal…
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Searchresult: Chromatin Networks
Our Research We integrate single-cell (epi)genomics with advanced fluorescence microscopy methods to understand how chromatin organization and nuclear architecture govern gene regulation and…
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Searchresult: Cancer Genome Research
Our Research Our research comprises the genome-wide analysis of molecular alterations in various cancer entities with an emphasis on lung and breast tumors. To this end, we apply high-throughput…
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Searchresult: Molecular Genome Analysis
Our Research The central objective of our division is to understand the complexity of molecular mechanisms in the regulation of signaling networks and how these impact cancer development,…
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Searchresult: Regulatory Genomics and Cancer Evolution
Our Research We are mainly an experimental genomics laboratory with long-standing collaborative alliances with other - particularly computational - research groups. The breadth of our three major…
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Searchresult: Translational Control and Metabolism
Our Research The demand for building blocks in cancer cells differs greatly from the one of a normal cell. In order to divide, a cell must duplicate its protein content, a process that requires…