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Research

Publications 2023

Journal Article Chen, X. (First author)DKFZ* ; Heisser, T.DKFZ* ; Cardoso, R.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Overall and age-specific risk advancement periods of colorectal cancer for men versus women: implications for gender-sensitive screening offers?
International journal of cancer 153(3), 547-551 (2023) [10.1002/ijc.34455]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Ugai, T. ; Haruki, K. ; Harrison, T. A. ; Cao, Y. ; Qu, C. ; Chan, A. T. ; Campbell, P. T. ; Akimoto, N. ; Berndt, S. ; Brenner, H.DKFZ* ; Buchanan, D. D. ; Chang-Claude, J.DKFZ* ; Fujiyoshi, K. ; Gallinger, S. J. ; Gunter, M. J. ; Hidaka, A. ; Hoffmeister, M.DKFZ* ; Hsu, L. ; Jenkins, M. A. ; Milne, R. L. ; Moreno, V. ; Newcomb, P. A. ; Nishihara, R. ; Pai, R. K. ; Sakoda, L. C. ; Slattery, M. L. ; Sun, W. ; Amitay, E.DKFZ* ; Alwers, E.DKFZ* ; Thibodeau, S. N. ; Toland, A. E. ; Van Guelpen, B. ; Woods, M. O. ; Zaidi, S. H. ; Potter, J. D. ; Giannakis, M. ; Song, M. ; Nowak, J. A. ; Phipps, A. I. ; Peters, U. ; Ogino, S.
Molecular Characteristics of Early-Onset Colorectal Cancer According to Detailed Anatomical Locations: Comparison With Later-Onset Cases.
The American journal of gastroenterology 118(4), 712-726 (2023) [10.14309/ajg.0000000000002171]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Mueller, S. H. ; Lai, A. G. ; Valkovskaya, M. ; et al
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry.
Genome medicine 15(1), 7 (2023) [10.1186/s13073-022-01152-5]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Mandic, M. (First author)DKFZ* ; Li, H.DKFZ* ; Safizadeh, F.DKFZ* ; Niedermaier, T.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Is the association of overweight and obesity with colorectal cancer underestimated? An umbrella review of systematic reviews and meta-analyses.
European journal of epidemiology 38(2), 135-144 (2023) [10.1007/s10654-022-00954-6]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Heisser, T. (First author)DKFZ* ; Kretschmann, J. ; Hagen, B. ; Niedermaier, T.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Prevalence of Colorectal Neoplasia 10 or More Years After a Negative Screening Colonoscopy in 120 000 Repeated Screening Colonoscopies.
JAMA internal medicine 183(3), 183-190 (2023) [10.1001/jamainternmed.2022.6215]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Ugai, T. ; Akimoto, N. ; Haruki, K. ; Harrison, T. A. ; Cao, Y. ; Qu, C. ; Chan, A. T. ; Campbell, P. T. ; Berndt, S. I. ; Buchanan, D. D. ; Cross, A. J. ; Diergaarde, B. ; Gallinger, S. J. ; Gunter, M. J. ; Harlid, S. ; Hidaka, A. ; Hoffmeister, M.DKFZ* ; Brenner, H.DKFZ* ; Chang-Claude, J.DKFZ* ; Hsu, L. ; Jenkins, M. A. ; Lin, Y. ; Milne, R. L. ; Moreno, V. ; Newcomb, P. A. ; Nishihara, R. ; Obon-Santacana, M. ; Pai, R. K. ; Sakoda, L. C. ; Schoen, R. E. ; Slattery, M. L. ; Sun, W. ; Amitay, E.DKFZ* ; Alwers, E.DKFZ* ; Thibodeau, S. N. ; Toland, A. E. ; Van Guelpen, B. ; Zaidi, S. H. ; Potter, J. D. ; Meyerhardt, J. A. ; Giannakis, M. ; Song, M. ; Nowak, J. A. ; Peters, U. ; Phipps, A. I. ; Ogino, S.
Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases.
Journal of gastroenterology 58(3), 229-245 (2023) [10.1007/s00535-023-01955-2]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Lindley, C. L. ; Gigic, B. ; Peoples, A. R. ; Han, C. J. ; Lin, T. ; Himbert, C. ; Warby, C. A. ; Boehm, J. ; Hardikar, S. ; Ashworth, A. ; Schneider, M. ; Ulrich, A. ; Schrotz-King, P.DKFZ* ; Figueiredo, J. C. ; Li, C. I. ; Shibata, D. ; Siegel, E. M. ; Toriola, A. T. ; Ulrich, C. M. ; Syrjala, K. L. ; Ose, J.
Pre-surgery inflammatory and angiogenesis biomarkers as predictors of 12-month cancer-related distress: Results from the ColoCare Study.
Cancer epidemiology, biomarkers & prevention 32(3), 363?370 (2023) [10.1158/1055-9965.EPI-22-0882]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Fernandez-Rozadilla, C. ; Timofeeva, M. ; Chen, Z. ; et al
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.
Nature genetics 55(1), 89-99 (2023) [10.1038/s41588-022-01222-9]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Alwers, E. (First author)DKFZ* ; Kather, J. N. ; Kloor, M.DKFZ* ; Brobeil, A. ; Tagscherer, K. E. ; Roth, W. ; Echle, A. ; Amitay, E.DKFZ* ; Chang-Claude, J.DKFZ* ; Brenner, H.DKFZ* ; Hoffmeister, M. (Last author)DKFZ*
Validation of the prognostic value of CD3 and CD8 cell densities analogous to the Immunoscore® by stage and location of colorectal cancer: an independent patient cohort study.
The journal of pathology: clinical research 9(2), 129-136 (2023) [10.1002/cjp2.304]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Heisser, T. (First author)DKFZ* ; Cardoso, R.DKFZ* ; Niedermaier, T.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Making colonoscopy-based screening more efficient: a 'gateopener' approach.
International journal of cancer 152(5), 952-961 (2023) [10.1002/ijc.34317]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Sha, S. (First author)DKFZ* ; Nguyen, T. M. N.DKFZ* ; Kuznia, S.DKFZ* ; Niedermaier, T.DKFZ* ; Zhu, A.DKFZ* ; Brenner, H.DKFZ* ; Schöttker, B. (Last author)DKFZ*
Real-world evidence for the effectiveness of vitamin D supplementation in reduction of total and cause-specific mortality.
Journal of internal medicine 293(3), 384-397 (2023) [10.1111/joim.13578]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Gregg, J. R. ; Kim, J. ; Logothetis, C. ; Hanash, S. ; Zhang, X. ; Manyam, G. ; Muir, K. ; Group, U. C. (Collaboration Author) ; Giles, G. G. ; Stanford, J. L. ; Berndt, S. I. ; Kogevinas, M. ; Brenner, H.DKFZ* ; Eeles, R. A. ; Consortium, P. (Collaboration Author) ; Wei, P. ; Daniel, C. R.
Coffee Intake, Caffeine Metabolism Genotype, and Survival Among Men with Prostate Cancer.
European urology oncology 6(3), 282-288 (2023) [10.1016/j.euo.2022.07.008]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Chen, H. ; Shi, J. ; Lu, M. ; Li, Y. ; Du, L. ; Liao, X. ; Wei, D. ; Dong, D. ; Gao, Y. ; Zhu, C. ; Ying, R. ; Zheng, W. ; Yan, S. ; Xiao, H. ; Zhang, J. ; Kong, Y. ; Li, F. ; Zou, S. ; Liu, C. ; Wang, H. ; Zhang, Y. ; Lu, B. ; Luo, C. ; Cai, J. ; Tian, J. ; Miao, X. ; Ding, K. ; Brenner, H.DKFZ* ; Dai, M.
Comparison of Colonoscopy, Fecal Immunochemical Test, and Risk-adapted Approach in a Colorectal Cancer Screening Trial (TARGET-C).
Clinical gastroenterology and hepatology 21(3), 808-818 (2023) [10.1016/j.cgh.2022.08.003]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Chen, X. (First author)DKFZ* ; Guo, F.DKFZ* ; Chang-Claude, J.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Physical activity, polygenic risk score, and colorectal cancer risk.
Cancer medicine 12(4), 4655-4666 (2023) [10.1002/cam4.5072]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Guo, F. (First author)DKFZ* ; Edelmann, D.DKFZ* ; Cardoso, R.DKFZ* ; Chen, X.DKFZ* ; Carr, P.DKFZ* ; Chang-Claude, J.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Polygenic risk score for defining personalized surveillance intervals after adenoma detection and removal at colonoscopy.
Clinical gastroenterology and hepatology 21(1), 210-219.e11 (2023) [10.1016/j.cgh.2022.03.013]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Goyal, N. ; Hennessy, M. ; Lehman, E. ; et al
Risk factors for head and neck cancer in more and less developed countries: Analysis from the INHANCE Consortium.
Oral diseases 29(4), 1565-1578 (2023) [10.1111/odi.14196]2023 BibTeX | EndNote: XML, Text | RIS

Dissertation / PhD Thesis Zhao, Z.DKFZ*
Fecal microRNAs for colorectal cancer early detection
Dissertation, Universität Heidelberg, 2023 Files BibTeX | EndNote: XML, Text | RIS

Journal Article Bull, C. ; Hazelwood, E. ; Bell, J. A. ; Tan, V. ; Constantinescu, A.-E. ; Borges, C. ; Legge, D. ; Burrows, K. ; Huyghe, J. R. ; Brenner, H.DKFZ* ; Castellvi-Bel, S. ; Chan, A. T. ; Kweon, S.-S. ; Le Marchand, L. ; Li, L. ; Cheng, I. ; Pai, R. K. ; Figueiredo, J. C. ; Murphy, N. ; Gunter, M. J. ; Timpson, N. J. ; Vincent, E. E.
Identifying metabolic features of colorectal cancer liability using Mendelian randomization.
eLife 12, RP87894 (2023) [10.7554/eLife.87894]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Schuppert, C. ; Rospleszcz, S. ; Hirsch, J. G. ; Hoinkiss, D. C. ; Köhn, A. ; von Krüchten, R. ; Russe, M. F. ; Keil, T. ; Krist, L. ; Schmidt, B. ; Michels, K. B. ; Schipf, S. ; Brenner, H.DKFZ* ; Kröncke, T. J. ; Pischon, T. ; Niendorf, T. ; Schulz-Menger, J. ; Forsting, M. ; Völzke, H. ; Hosten, N. ; Bülow, R. ; Zaitsev, M. ; Kauczor, H.-U. ; Bamberg, F. ; Günther, M. ; Schlett, C. L.
Automated image quality assessment for selecting among multiple magnetic resonance image acquisitions in the German National Cohort study.
Scientific reports 13(1), 22745 (2023) [10.1038/s41598-023-49569-1]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Jiang, X. ; Hoffmeister, M.DKFZ* ; Brenner, H.DKFZ* ; Muti, H. S. ; Yuan, T.DKFZ* ; Foersch, S. ; West, N. P. ; Brobeil, A. ; Jonnagaddala, J. ; Hawkins, N. ; Ward, R. L. ; Brinker, T.DKFZ* ; Saldanha, O. L. ; Ke, J. ; Müller, W. ; Grabsch, H. I. ; Quirke, P. ; Truhn, D. ; Kather, J. N.
End-to-end prognostication in colorectal cancer by deep learning: a retrospective, multicentre study.
The lancet / Digital health 6(1), e33 - e43 (2024) [10.1016/S2589-7500(23)00208-X]2024 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Truhn, D. ; Tayebi Arasteh, S. ; Saldanha, O. L. ; Müller-Franzes, G. ; Khader, F. ; Quirke, P. ; West, N. P. ; Gray, R. ; Hutchins, G. G. A. ; James, J. A. ; Loughrey, M. B. ; Salto-Tellez, M. ; Brenner, H.DKFZ* ; Brobeil, A. ; Yuan, T.DKFZ* ; Chang-Claude, J.DKFZ* ; Hoffmeister, M.DKFZ* ; Foersch, S. ; Han, T. ; Keil, S. ; Schulze-Hagen, M. ; Isfort, P. ; Bruners, P. ; Kaissis, G. ; Kuhl, C. ; Nebelung, S. ; Kather, J. N.
Encrypted federated learning for secure decentralized collaboration in cancer image analysis.
Medical image analysis 92, 103059 (2023) [10.1016/j.media.2023.103059]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Etemad, M. ; Christodoulou, F. ; Uhlig, S. ; Hassel, J. C. ; Schrotz-King, P.DKFZ* ; Brenner, H.DKFZ* ; Ulrich, C. M. ; Bieback, K. ; Klüter, H. ; Bugert, P.
C-Type Lectin-like Receptor 2 Expression Is Decreased upon Platelet Activation and Is Lower in Most Tumor Entities Compared to Healthy Controls.
Cancers 15(23), 5514 (2023) [10.3390/cancers15235514]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Li, X. (First author)DKFZ* ; Stassen, L.DKFZ* ; Schrotz-King, P.DKFZ* ; Zhao, Z.DKFZ* ; Cardoso, R.DKFZ* ; Raut, J. R.DKFZ* ; Bhardwaj, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Potential of Fecal Carcinoembryonic Antigen for Noninvasive Detection of Colorectal Cancer: A Systematic Review.
Cancers 15(23), 5656 (2023) [10.3390/cancers15235656]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Malagón, M. ; Alwers, E.DKFZ* ; Oliver, L. ; Ramió-Pujol, S. ; Sánchez-Vizcaino, M. ; Amoedo, J. ; de Cambra, S. ; Serra-Pagès, M. ; Castells, A. ; Aldeguer, X. ; Garcia-Gil, J. ; Brenner, H. (Last author)DKFZ*
Clinical performance study of a fecal bacterial signature test for colorectal cancer screening.
PLOS ONE 18(11), e0293678 - (2023) [10.1371/journal.pone.0293678]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Zanti, M. ; O'Mahony, D. G. ; Parsons, M. T. ; et al
A Likelihood Ratio Approach for Utilizing Case-Control Data in the Clinical Classification of Rare Sequence Variants: Application to BRCA1 and BRCA2
Human mutation 2023, 9961341 (2023) [10.1155/2023/9961341]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Maia, C. E. G. ; Trevisan, M. T. S. ; Owen, R. W. ; Breuer, A.DKFZ* ; Monte, E. S. P. ; da Silva, F. L. F. ; Marques, S. P. D.
Impacts of glyphosate and nitrogen sources on the glycation process and dicarbonyl scavenging capacity of mangiferin through the formation of mangiferin-MGO adducts
Food chemistry advances 3, 100516 (2023) [10.1016/j.focha.2023.100516]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Wang, A. ; Shen, J. ; Rodriguez, A. A. ; et al
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants
Nature genetics 55(12), 2065-2074 (2023) [10.1038/s41588-023-01534-4]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Niedermaier, T. (First author)DKFZ* ; Heisser, T.DKFZ* ; Cardoso, R.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Colonoscopy-Ascertained Prevalence of Advanced Neoplasia According to Fecal Hemoglobin Concentration in a Large Cohort of Fecal Immunochemical Test-Negative Screening Participants.
Annals of internal medicine 176(11), 1569-1571 (2023) [10.7326/M23-1358]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Chen, X. (First author)DKFZ* ; Heisser, T.DKFZ* ; Cardoso, R.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Personalized Initial Screening Age for Colorectal Cancer in Individuals at Average Risk.
JAMA network open 6(10), e2339670 (2023) [10.1001/jamanetworkopen.2023.39670]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article (Letter) Chen, X. (First author)DKFZ* ; Heisser, T.DKFZ* ; Cardoso, R.DKFZ* ; Hibbert, J.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Beyond familial risk: deriving risk-adapted starting ages of screening among people with a family history of colorectal cancer.
Cancer communications 43(12), 1377-1380 (2023) [10.1002/cac2.12499]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article (Letter) Brenner, H. (First author)DKFZ* ; Heisser, T.DKFZ* ; Cardoso, R.DKFZ* ; Hoffmeister, M. (Last author)DKFZ*
Which results would the NordICC trial have found if screening colonoscopy had prevented all incident colorectal cancers?
Gastrointestinal endoscopy 98(5), 878 - 879 (2023) [10.1016/j.gie.2023.06.059]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Wichert, K. ; Hoppe, R. ; Ickstadt, K. ; Behrens, T. ; Winter, S. ; Herold, R. ; Terschüren, C. ; Lo, W.-Y. ; Guénel, P. ; Truong, T. ; Bolla, M. K. ; Wang, Q. ; Dennis, J. ; Michailidou, K. ; Lush, M. ; Andrulis, I. L. ; Brenner, H.DKFZ* ; Chang-Claude, J.DKFZ* ; Cox, A. ; Cross, S. S. ; Czene, K. ; Eriksson, M. ; Figueroa, J. D. ; García-Closas, M. ; Goldberg, M. S. ; Hamann, U.DKFZ* ; He, W. ; Holleczek, B. ; Hopper, J. L. ; Jakubowska, A. ; Ko, Y.-D. ; Lubi?ski, J. ; Mulligan, A. M. ; Obi, N. ; Rhenius, V. ; Shah, M. ; Shu, X.-O. ; Simard, J. ; Southey, M. C. ; Zheng, W. ; Dunning, A. M. ; Pharoah, P. D. P. ; Hall, P. ; Easton, D. F. ; Brüning, T. ; Brauch, H.DKFZ* ; Harth, V. ; Rabstein, S.
Polymorphisms in genes of melatonin biosynthesis and signaling support the light-at-night hypothesis for breast cancer.
European journal of epidemiology 38(10), 1053-1068 (2023) [10.1007/s10654-023-01048-7]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Thomas, M. ; Su, Y.-R. ; Rosenthal, E. A. ; et al
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations.
Nature Communications 14(1), 6147 (2023) [10.1038/s41467-023-41819-0]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Höhn, J. (First author)DKFZ* ; Krieghoff-Henning, E. (First author)DKFZ* ; Wies, C.DKFZ* ; Kiehl, L.DKFZ* ; Hetz, M. J.DKFZ* ; Bucher, T.DKFZ* ; Jonnagaddala, J. ; Zatloukal, K. ; Müller, H. ; Plass, M. ; Jungwirth, E. ; Gaiser, T. ; Steeg, M. ; Holland-Letz, T.DKFZ* ; Brenner, H.DKFZ* ; Hoffmeister, M. (Last author)DKFZ* ; Brinker, T. (Last author)DKFZ*
Colorectal cancer risk stratification on histological slides based on survival curves predicted by deep learning.
npj precision oncology 7(1), 98 (2023) [10.1038/s41698-023-00451-3]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Giaccherini, M. ; Gori, L. ; Gentiluomo, M. ; et al
A scan of all coding region variants of the human genome, identifies 13q12.2-rs9579139 and 15q24.1-rs2277598 as novel risk loci for pancreatic ductal adenocarcinoma.
Carcinogenesis 44(8-9), 642-649 (2023) [10.1093/carcin/bgad056]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Wagner, S. J. ; Reisenbüchler, D. ; West, N. P. ; et al
Transformer-based biomarker prediction from colorectal cancer histology: A large-scale multicentric study.
Cancer cell 49(1), 1650-1661.e4 (2023) [10.1016/j.ccell.2023.08.002]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Rehm, M. ; Jaensch, A. ; Schöttker, B.DKFZ* ; Mons, U.DKFZ* ; Hahmann, H. ; Koenig, W. ; Brenner, H.DKFZ* ; Rothenbacher, D. (Last author)DKFZ*
Medical care and biomarker-based assessment of mortality in two cohorts of patients with chronic coronary syndrome 10 years apart.
BMC cardiovascular disorders 23(1), 428 (2023) [10.1186/s12872-023-03469-4]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Bouras, E. ; Kim, A. E. ; Lin, Y. ; et al
Genome-wide interaction analysis of folate for colorectal cancer risk.
The American journal of clinical nutrition 118(5), 881-891 (2023) [10.1016/j.ajcnut.2023.08.010]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Fares, A. F. ; Li, Y. ; Jiang, M. ; et al
Association between duration of smoking abstinence before non-small-cell lung cancer diagnosis and survival: a retrospective, pooled analysis of cohort studies.
The lancet / Public health 8(9), e691 - e700 (2023) [10.1016/S2468-2667(23)00131-7]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Pham, T. T. ; Nimptsch, K. ; Papadimitriou, N. ; Aleksandrova, K. ; Jenab, M. ; Gunter, M. J. ; Le Marchand, L. ; Li, L. ; Lynch, B. M. ; Castellví-Bel, S. ; Phipps, A. I. ; Schmit, S. L. ; Brenner, H.DKFZ* ; Ogino, S. ; Giovannucci, E. ; Pischon, T.
Genetically determined circulating resistin concentrations and risk of colorectal cancer: a two-sample Mendelian randomization study.
Journal of cancer research and clinical oncology 149(16), 14889-14900 (2023) [10.1007/s00432-023-05193-0]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Liu, Z. (First author)DKFZ* ; Thong, M. S. Y.DKFZ* ; Doege, D.DKFZ* ; Koch-Gallenkamp, L.DKFZ* ; Weisser, L.DKFZ* ; Bertram, H. ; Eberle, A. ; Holleczek, B. ; Nennecke, A. ; Waldmann, A. ; Zeissig, S. R. ; Pritzkuleit, R. ; Brenner, H.DKFZ* ; Arndt, V. (Last author)DKFZ*
Benefit finding, posttraumatic growth and health-related quality of life in long-term cancer survivors: a prospective population-based study.
Acta oncologica 62(9), 1124-1131 (2023) [10.1080/0284186X.2023.2245560]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Piccardi, M. ; Gentiluomo, M. ; Bertoncini, S. ; et al
Exploring the Neandertal legacy of pancreatic ductal adenocarcinoma risk in Eurasians.
Biological research 56(1), 46 (2023) [10.1186/s40659-023-00457-y]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Middha, P. (First author)DKFZ* ; Wang, X. ; Behrens, S.DKFZ* ; et al
A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry.
Breast cancer research 25(1), 93 (2023) [10.1186/s13058-023-01691-8]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Sha, S. (First author)DKFZ* ; Chen, L.-J.DKFZ* ; Brenner, H.DKFZ* ; Schöttker, B. (Last author)DKFZ*
Associations of 25-hydroxyvitamin D status and vitamin D supplementation use with mortality due to 18 frequent cancer types in the UK Biobank cohort.
European journal of cancer 191, 113241 (2023) [10.1016/j.ejca.2023.113241]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Park, H. A. (First author)DKFZ* ; Edelmann, D.DKFZ* ; Canzian, F.DKFZ* ; Seibold, P.DKFZ* ; Harrison, T. A. ; Hua, X. ; Shi, Q. ; Silverman, A. ; Benner, A.DKFZ* ; Macauda, A.DKFZ* ; Schneider, M. ; Goldberg, R. M. ; Alberts, S. R. ; Hoffmeister, M.DKFZ* ; Brenner, H.DKFZ* ; Chan, A. T. ; Peters, U. ; Newcomb, P. A. ; Chang-Claude, J. (Last author)DKFZ*
Genome-wide study of genetic polymorphisms predictive for outcome from first-line oxaliplatin-based chemotherapy in colorectal cancer patients.
International journal of cancer 153(9), 1623-1634 (2023) [10.1002/ijc.34663]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Brenner, H. (First author)DKFZ* ; Heisser, T.DKFZ* ; Cardoso, R.DKFZ* ; Hoffmeister, M. (Last author)DKFZ*
When gold standards are not so golden: prevalence bias in randomized trials on endoscopic colorectal cancer screening.
European journal of epidemiology 38(9), 933-937 (2023) [10.1007/s10654-023-01031-2]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Levi, H. ; Carmi, S. ; Rosset, S. ; et al
Evaluation of European-based polygenic risk score for breast cancer in Ashkenazi Jewish women in Israel.
Journal of medical genetics 60(12), 1186-1197 (2023) [10.1136/jmg-2023-109185]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Mahmood, K. ; Thomas, M. ; Qu, C. ; et al
Elucidating the risk of colorectal cancer for variants in hereditary colorectal cancer genes.
Gastroenterology 165(4), 1070-1076.e3 (2023) [10.1053/j.gastro.2023.06.032]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article (Editorial) Brenner, H. (Last author)DKFZ*
The Role of Vitamin D for Human Health: The Challenge of the Right Study Designs and Interpretation.
Nutrients 15(13), 2897 (2023) [10.3390/nu15132897]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Safizadeh, F. (First author)DKFZ* ; Mandic, M.DKFZ* ; Pulte, D.DKFZ* ; Niedermaier, T.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
The underestimated impact of excess body weight on colorectal cancer risk: Evidence from the UK Biobank cohort.
British journal of cancer 129(5), 829-837 (2023) [10.1038/s41416-023-02351-6]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Ose, J. ; Gigic, B. ; Brezina, S. ; Lin, T. ; Peoples, A. R. ; Schobert, P. P. ; Baierl, A. ; van Roekel, E. ; Robinot, N. ; Gicquiau, A. ; Achaintre, D. ; Scalbert, A. ; van Duijnhoven, F. J. B. ; Holowatyj, A. N. ; Gumpenberger, T. ; Schrotz-King, P.DKFZ* ; Ulrich, A. B. ; Ulvik, A. ; Ueland, P.-M. ; Weijenberg, M. P. ; Habermann, N. ; Keski-Rahkonen, P. ; Gsur, A. ; Kok, D. E. ; Ulrich, C. M.
Higher Plasma Creatinine Is Associated with an Increased Risk of Death in Patients with Non-Metastatic Rectal but Not Colon Cancer: Results from an International Cohort Consortium
Cancers 15(13), 3391 (2023) [10.3390/cancers15133391]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article (Erratum/Correction) Hess, T. ; Maj, C. ; Gehlen, J. ; et al
Corrigendum to 'Dissecting the genetic heterogeneity of gastric cancer'.
EBioMedicine 94, 104709 (2023) [10.1016/j.ebiom.2023.104709]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Gwenzi, T. (First author)DKFZ* ; Zhu, A.DKFZ* ; Schrotz-King, P.DKFZ* ; Schöttker, B.DKFZ* ; Hoffmeister, M.DKFZ* ; Edelmann, D.DKFZ* ; Brenner, H. (Last author)DKFZ*
Prognostic Value of Post-Operative C-Reactive Protein-Based Inflammatory Biomarkers in Colorectal Cancer Patients: Systematic Review and Meta-Analysis.
Clinical epidemiology 15, 795 - 809 (2023) [10.2147/CLEP.S415171]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Di Castelnuovo, A. ; Bonaccio, M. ; Costanzo, S. ; McElduff, P. ; Linneberg, A. ; Salomaa, V. ; Männistö, S. ; Ferrières, J. ; Dallongeville, J. ; Thorand, B. ; Brenner, H.DKFZ* ; Ferrario, M. ; Veronesi, G. ; Tamosiunas, A. ; Grimsgaard, S. ; Drygas, W. ; Malyutina, S. ; Söderberg, S. ; Nordendahl, M. ; Kee, F. ; Grassi, G. ; Dabboura, S. ; Borchini, R. ; Westermann, D. ; Schrage, B. ; Zeller, T. ; Kuulasmaa, K. ; Blankenberg, S. ; Donati, M. B. ; Iacoviello, L. ; Investigators, M. S. (Collaboration Author) ; de Gaetano, G.
Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level: findings from the MORGAM project.
European journal of epidemiology 38(8), 869-881 (2023) [10.1007/s10654-023-01022-3]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Vlaski, T. (First author)DKFZ* ; Slavic, M.DKFZ* ; Caspari, R. ; Fischer, H. ; Brenner, H.DKFZ* ; Schöttker, B. (Last author)DKFZ*
Development Trajectories of Fatigue, Quality of Life, and the Ability to Work among Colorectal Cancer Patients in the First Year after Rehabilitation-First Results of the MIRANDA Study.
Cancers 15(12), 3168 (2023) [10.3390/cancers15123168]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Gwenzi, T. (First author)DKFZ* ; Schrotz-King, P.DKFZ* ; Schöttker, B.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Vitamin D Status, Cdx2 Genotype, and Colorectal Cancer Survival: Population-Based Patient Cohort.
Nutrients 15(12), 2717 (2023) [10.3390/nu15122717]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Dimou, N. ; Kim, A. E. ; Flanagan, O. ; et al
Probing the diabetes and colorectal cancer relationship using gene - environment interaction analyses.
British journal of cancer 129(3), 511-520 (2023) [10.1038/s41416-023-02312-z]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Sha, S. (First author)DKFZ* ; Gwenzi, T.DKFZ* ; Chen, L.-J.DKFZ* ; Brenner, H.DKFZ* ; Schöttker, B. (Last author)DKFZ*
About the associations of vitamin D deficiency and biomarkers of systemic inflammatory response with all-cause and cause-specific mortality in a general population sample of almost 400,000 UK Biobank participants.
European journal of epidemiology 38(9), 957-971 (2023) [10.1007/s10654-023-01023-2]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Yuan, T. (First author)DKFZ* ; Edelmann, D.DKFZ* ; Fan, Z.DKFZ* ; Alwers, E.DKFZ* ; Kather, J. N. ; Brenner, H.DKFZ* ; Hoffmeister, M. (Last author)DKFZ*
Machine learning in the identification of prognostic DNA methylation biomarkers among patients with cancer: A systematic review of epigenome-wide studies
Artificial intelligence in medicine 143, 102589 (2023) [10.1016/j.artmed.2023.102589]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Darst, B. F. ; Shen, J. ; Madduri, R. K. ; et al
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.
The American journal of human genetics 110(7), 1200-1206 (2023) [10.1016/j.ajhg.2023.05.010]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article (Letter) Bhardwaj, M. (First author)DKFZ* ; Schöttker, B.DKFZ* ; Holleczek, B.DKFZ* ; Brenner, H. (Last author)DKFZ*
Enhanced selection of people for lung cancer screening using AHRR (cg05575921) or F2RL3 (cg03636183) methylation as biological markers of smoking exposure.
Cancer communications 43(8), 956-959 (2023) [10.1002/cac2.12450]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article (Letter) Niedermaier, T. (First author)DKFZ* ; Alwers, E.DKFZ* ; Chen, X.DKFZ* ; Heisser, T.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
A single measurement of fecal hemoglobin concentration outperforms polygenic risk score in colorectal cancer risk assessment.
Cancer communications 43(8), 947-950 (2023) [10.1002/cac2.12448]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Klimeck, L. (First author)DKFZ* ; Heisser, T.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Colorectal cancer: A health and economic problem
Best practice & research / Clinical gastroenterology 66, 101839 (2023) [10.1016/j.bpg.2023.101839]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Gwenzi, T. (First author)DKFZ* ; Zhu, A.DKFZ* ; Schrotz-King, P.DKFZ* ; Schöttker, B.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Effects of vitamin D supplementation on inflammatory response in patients with cancer and precancerous lesions: Systematic review and meta-analysis of randomized trials.
Clinical nutrition 42(7), 1142-1150 (2023) [10.1016/j.clnu.2023.05.009]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Hess, T. ; Maj, C. ; Gehlen, J. ; et al
Dissecting the genetic heterogeneity of gastric cancer.
EBioMedicine 92, 104616 (2023) [10.1016/j.ebiom.2023.104616]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Campa, D. ; Gentiluomo, M. ; Stein, A.DKFZ* ; et al
The PANcreatic Disease ReseArch (PANDoRA) consortium: ten years' experience of association studies to understand the genetic architecture of pancreatic cancer.
Critical reviews in oncology, hematology 186, 104020 (2023) [10.1016/j.critrevonc.2023.104020]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Chen, T. ; Kharazmi, E.DKFZ* ; Fallah, M. (Last author)DKFZ*
Race and Ethnicity?Adjusted Age Recommendation for Initiating Breast Cancer Screening
JAMA network open 6(4), e238893 (2023) [10.1001/jamanetworkopen.2023.8893]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Mandic, M. (First author)DKFZ* ; Safizadeh, F.DKFZ* ; Niedermaier, T.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Association of Overweight, Obesity, and Recent Weight Loss With Colorectal Cancer Risk.
JAMA network open 6(4), e239556 (2023) [10.1001/jamanetworkopen.2023.9556]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article Schöttker, B. (First author)DKFZ* ; Chen, L.-J.DKFZ* ; Caspari, R. ; Brenner, H. (Last author)DKFZ*
Protocol of the optimal study: Optimization of polypharmacy in geriatric oncology - A randomized controlled trial.
BMC cancer 23(1), 357 (2023) [10.1186/s12885-023-10812-7]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Kharazmi, E. (First author)DKFZ* ; Scherer, D. ; Boekstegers, F. ; Liang, Q.DKFZ* ; Sundquist, K. ; Sundquist, J. ; Fallah, M. (Last author)DKFZ* ; Bermejo, J. L.
Gallstones, cholecystectomy and kidney cancer: observational and Mendelian randomisation results based on large cohorts.
Gastroenterology 165(1), 218-227.e8 (2023) [10.1053/j.gastro.2023.03.227]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article (Review Article) Kuznia, S. (First author)DKFZ* ; Zhu, A.DKFZ* ; Akutsu, T. ; Buring, J. E. ; Camargo, C. A. ; Cook, N. R. ; Chen, L.-J.DKFZ* ; Cheng, T. D. ; Hantunen, S. ; Lee, I.-M. ; Manson, J. E. ; Neale, R. E. ; Scragg, R. ; Shadyab, A. H. ; Sha, S.DKFZ* ; Sluyter, J. ; Tuomainen, T.-P. ; Urashima, M. ; Virtanen, J. K. ; Voutilainen, A. ; Wactawski-Wende, J. ; Waterhouse, M. ; Brenner, H.DKFZ* ; Schöttker, B. (Last author)DKFZ*
Efficacy of vitamin D3 supplementation on cancer mortality: systematic review and individual patient data meta-analysis of randomised controlled trials.
Ageing research reviews 87, 101923 (2023) [10.1016/j.arr.2023.101923]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Thong, M. (First author)DKFZ* ; Doege, D.DKFZ* ; Weißer, L.DKFZ* ; Koch-Gallenkamp, L.DKFZ* ; Jansen, L.DKFZ* ; Bertram, H. ; Eberle, A. ; Holleczek, B. ; Nennecke, A. ; Waldmann, A. ; Zeissig, S. R. ; Brenner, H.DKFZ* ; Arndt, V. (Last author)DKFZ*
Persisting Deficits in Health-Related Quality of Life of Colorectal Cancer Survivors 14-24 Years Post-Diagnosis: A Population-Based Study.
Current oncology 30(3), 3373 - 3390 (2023) [10.3390/curroncol30030257]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Niehues, J. M. ; Quirke, P. ; West, N. P. ; Grabsch, H. I. ; van Treeck, M. ; Schirris, Y. ; Veldhuizen, G. P. ; Hutchins, G. G. A. ; Richman, S. D. ; Foersch, S. ; Brinker, T.DKFZ* ; Fukuoka, J. ; Bychkov, A. ; Uegami, W. ; Truhn, D. ; Brenner, H.DKFZ* ; Brobeil, A. ; Hoffmeister, M.DKFZ* ; Kather, J. N.
Generalizable biomarker prediction from cancer pathology slides with self-supervised deep learning: A retrospective multi-centric study.
Cell reports / Medicine 4, 100980 (2023) [10.1016/j.xcrm.2023.100980]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Cardoso, R. (First author)DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Breast cancer screening programmes and self-reported mammography use in European countries.
International journal of cancer 152(12), 2512-2527 (2023) [10.1002/ijc.34494]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Niedermaier, T. (First author)DKFZ* ; Gredner, T. (First author)DKFZ* ; Hoffmeister, M.DKFZ* ; Mons, U.DKFZ* ; Brenner, H. (Last author)DKFZ*
Impact of Reducing Intake of Red and Processed Meat on Colorectal Cancer Incidence in Germany 2020 to 2050-A Simulation Study.
Nutrients 15(4), 1020 (2023) [10.3390/nu15041020]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

Journal Article (Erratum/Correction) Fernandez-Rozadilla, C. ; Timofeeva, M. ; Chen, Z. ; et al
Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.
Nature genetics 55(3), 519-520 (2023) [10.1038/s41588-023-01334-w]2023 BibTeX | EndNote: XML, Text | RIS

Journal Article Li, H. (First author)DKFZ* ; Chen, X.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H. (Last author)DKFZ*
Associations of smoking with early- and late-onset colorectal cancer.
JNCI cancer spectrum 7(1), pkad004 (2023) [10.1093/jncics/pkad004]2023 DBCoverage BibTeX | EndNote: XML, Text | RIS

Journal Article Massi, M. C. ; Franco, N. R. ; Manzoni, A. ; Paganoni, A. M. ; Park, H. A.DKFZ* ; Hoffmeister, M.DKFZ* ; Brenner, H.DKFZ* ; Chang-Claude, J.DKFZ* ; Ieva, F. ; Zunino, P.
Learning high-order interactions for polygenic risk prediction.
PLOS ONE 18(2), e0281618 - (2023) [10.1371/journal.pone.0281618]2023 DBCoverage Fulltext by Pubmed Central BibTeX | EndNote: XML, Text | RIS

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