Sabine Schmidt, Dipl.-Ing. (FH) Biotechnologie

Scientific CV

Since August 2019
Engineer Biotechnology, Division of Microbiome and Cancer
DKFZ Heidelberg

2011 - 2019
Lab Manager Sequencing, High Throughput Sequencing,
Genomics and Proteomics Core Facility, DKFZ Heidelberg

2001 - 2011
Technical Officer Microarrays, Genomics Core Facility, EMBL Heidelberg

1999 – 2001
Research Engineer Expression Profiling, LION bioscience AG Heidelberg

1995 - 1998
Dipl.-Ing. (FH) Biotechnologie, University of Applied Sciences, Mannheim

Selected Publications

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study
Worst BC, van Tilburg CM, Balasubramanian GP, Fiesel P, Witt R, Freitag A, Boudalil M, Previti C, Wolf S, Schmidt S, Chotewutmontri S, Bewerunge-Hudler M, Schick M, Schlesner M, Hutter B, Taylor L, Borst T, Sutter C, Bartram CR, Milde T, Pfaff E, Kulozik AE, von Stackelberg A, Meisel R, Borkhardt A, Reinhardt D, Klusmann JH, Fleischhack G, Tippelt S, Dirksen U, Jürgens H, Kramm CM, von Bueren AO, Westermann F, Fischer M, Burkhardt B, Wößmann W, Nathrath M, Bielack SS, Frühwald MC, Fulda S, Klingebiel T, Koscielniak E, Schwab M, Tremmel R, Driever PH, Schulte JH, Brors B, von Deimling A, Lichter P, Eggert A, Capper D, Pfister SM, Jones DT, Witt O., Eur J Cancer (2016) Sep;65:91-101.

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S, Korshunov A, Tarpey PS, Butler AP, Hinton J, Jones D, Menzies A, Raine K, Shepherd R, Stebbings L, Teague JW, Ribeca P, Giner FC, Beltran S, Raineri E, Dabad M, Heath SC, Gut M, Denroche RE, Harding NJ, Yamaguchi TN, Fujimoto A, Nakagawa H, Quesada V, Valdés-Mas R, Nakken S, Vodák D, Bower L, Lynch AG, Anderson CL, Waddell N, Pearson JV, Grimmond SM, Peto M, Spellman P, He M, Kandoth C, Lee S, Zhang J, Létourneau L, Ma S, Seth S, Torrents D, Xi L, Wheeler DA, López-Otín C, Campo E, Campbell PJ, Boutros PC, Puente XS, Gerhard DS, Pfister SM, McPherson JD, Hudson TJ, Schlesner M, Lichter P, Eils R, Jones DT, Gut IG., Nat Commun. 2015 Dec 9;6:10001..

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing
Hovestadt V., Jones D. T., Picelli S., Wang W., Kool M., Northcott P. A., Sultan M., Stachurski K., Ryzhova M., Warnatz H. J., Ralser M., Brun S., Bunt J., Jager N., Kleinheinz K., Erkek S., Weber U. D., Bartholomae C. C., von Kalle C., Lawerenz C., Eils J., Koster J., Versteeg R., Milde T., Witt O., Schmidt S., Wolf S., Pietsch T., Rutkowski S., Scheurlen W., Taylor M. D., Brors B., Felsberg J., Reifenberger G., Borkhardt A., Lehrach H., Wechsler-Reya R. J., Eils R., Yaspo M. L., Landgraf P., Korshunov A., Zapatka M., Radlwimmer B., Pfister S. M., Lichter P., (2014)., Nature, 510:537-41

Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition Kool M., Jones D. T., Jager N., Northcott P. A., Pugh T. J., Hovestadt V., Piro R. M., Esparza L. A., Markant S. L., Remke M., Milde T., Bourdeaut F., Ryzhova M., Sturm D., Pfaff E., Stark S., Hutter S., Seker-Cin H., Johann P., Bender S., Schmidt C., Rausch T., Shih D., Reimand J., Sieber L., Wittmann A., Linke L., Witt H., Weber U. D., Zapatka M., Konig R., Beroukhim R., Bergthold G., van Sluis P., Volckmann R., Koster J., Versteeg R., Schmidt S, Wolf S, Lawerenz C., Bartholomae C. C., von Kalle C., Unterberg A., Herold-Mende C., Hofer S., Kulozik A. E., von Deimling A., Scheurlen W., Felsberg J., Reifenberger G., Hasselblatt M., Crawford J. R., Grant G. A., Jabado N., Perry A., Cowdrey C., Croul S., Zadeh G., Korbel J. O., Doz F., Delattre O., Bader G. D., McCabe M. G., Collins V. P., Kieran M. W., Cho Y. J., Pomeroy S. L., Witt O., Brors B., Taylor M. D., Schuller U., Korshunov A., Eils R., Wechsler-Reya R. J., Lichter P., Pfister S. M., Icgc PedBrain Tumor Project, (2014)., Cancer Cell, 25:393-405