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Prof. Dr. Michael Hoffmeister

Position:

Deputy Division Head, Group Head

Contact:

Contact Form

Phone:

+49 (0)6221 42-1303

Fax:

+49 (0)6221 42-1302

Building:

Im Neuenheimer Feld 581

Room:

S 1.200

Deputy Division Head
Group Head "Molecular Pathological Epidemiology"

Research focuses

Colorectal cancer prevention
Screening & early detecton
Risk and prognostic factors
Molecular pathological epidemiology

Current research projects, studies, activities

PEARL Study, PEARL Consortium, DACHS Study, BLITZ Study,
Smartphone-based stool test, IMPACT Consortium, KolosSal Study,
GECCO Consortium, DARIO Study, GEKKO Study, LEO Study, UK Biobank,
MiCCroBioTackle Consortium

Promotion committee (PhD), Medical Faculty, University of Heidelberg
UNCAN.eu: a European initiative to better understand cancer
ECICC: European Commission Initiative on Colorectal Cancer
BBMRI: Biobanking and Biomolecular Resources Research Infrastructure

Current group members MPE

Tanwei Yuan, MSc
Jie Ding, MSc
Durgesh Wankhede, MS

Former group members MPE

Elizabeth Alwers, PhD
Efrat Amitay, PhD
Prudence Carr, PhD
Marie Wosny, MSc
Margherita D'Errico, MSc
Stefanie Bienert, MSc
Min Jia, PhD

Publications

→ Articles in PubMed

Selected publications

Wankhede D, Yuan T, Kloor M, Halama N, Brenner H, Hoffmeister M. Clinical significance of combined tumour-infiltrating lymphocytes and microsatellite instability status in colorectal cancer: a systematic review and network meta-analysis. Lancet Gastroenterol Hepatol 2024;9(7):609-619.

Hoffmeister M, Cardoso R, Brenner H. Colonoscopy Screening and Colorectal Cancer Incidence and Mortality. N Engl J Med 2023;388(4):377-378.

Hoffmeister M. Interim evaluation of the colorectal cancer screening programme in the Netherlands. Lancet Gastroenterol Hepatol 2022;7(1):8-9.

Cardoso R, ..., Hoffmeister M, Brenner H. Colorectal cancer incidence, mortality, and stage distribution in European countries in the colorectal cancer screening era: an international population-based study. Lancet Oncol 2021;22(7):1002-1013.

Hoffmeister M, Brenner H, Amitay EL. Smoking Is Consistently Associated With Major Molecular Subtypes of Colorectal Cancer. Am J Gastroenterol 2021;116(5):1092-1093.

Hoffmeister M, Bläker H, Jansen L, Alwers E, Amitay EL, Carr PR, Kloor M, Herpel E, Roth W, Chang-Claude J, Brenner H. Colonoscopy and Reduction of Colorectal Cancer Risk by Molecular Tumor Subtypes: A Population-Based Case-Control Study. Am J Gastroenterol 2020;115(12):2007-2016.

Kather JN, Pearson AT, Halama N, Jäger D, Krause J, Loosen SH, Marx A, Boor P, Tacke F, Neumann UP, Grabsch HI, Yoshikawa T, Brenner H, Chang-Claude J, Hoffmeister M, Trautwein C, Luedde T. Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer. Nat Med 2019;25(7):1054-56.

Amitay EL, Carr PR, Jansen L, Walter V, Roth W, Herpel E, Kloor M, Bläker H, Chang-Claude J, Brenner H, Hoffmeister M. Association of Aspirin and Nonsteroidal Anti-Inflammatory Drugs With Colorectal Cancer Risk by Molecular Subtypes. J Natl Cancer Inst 2019;111(5):475-83.

Lauby-Secretan B, Vilahur N, Bianchini F, Guha N, Straif K; International Agency for Research on Cancer Handbook Working Group. The IARC Perspective on Colorectal Cancer Screening. N Engl J Med 2018;378(18):1734-40.

Carr PR, Weigl K, Jansen L, Walter V, Erben V, Chang-Claude J, Brenner H, Hoffmeister M. Healthy Lifestyle Factors Associated With Lower Risk of Colorectal Cancer Irrespective of Genetic Risk. Gastroenterology 2018;155(6):1805-15.

Research

Prof. Dr. Michael Hoffmeister

Deputy Division HeadGroup Head "Molecular Pathological Epidemiology"

Deputy Division Head
Group Head "Molecular Pathological Epidemiology"