Publications of Molecular Genetics
2021
Combining ibrutinib and checkpoint blockade improves CD8+ T-cell function and control of chronic lymphocytic leukemia in Em-TCL1 mice.
Haematologica 106(4), 968-977 (2021) [10.3324/haematol.2019.238154]
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A versatile system to introduce clusters of genomic double-strand breaks in large cell populations.
Genes, chromosomes & cancer 60(5), 303-313 (2021) [10.1002/gcc.22890]
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Unraveling most abundant mutational signatures in head and neck cancer
International journal of cancer 148(1), 115-127 (2021) [10.1002/ijc.33297]
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Antibody peptides as cancer vaccine - turning weapons to targets.
Clinical cancer research 27(3), 659-661 (2021) [10.1158/1078-0432.CCR-20-3977]
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A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors.
Cancers 13(2), 230 (2021) [10.3390/cancers13020230]
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Evidence for multi-copy Mega-NUMTs in the human genome.
Nucleic acids research 49(3), 1517-1531 (2021) [10.1093/nar/gkaa1271]
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TLR9 expression in Chronic Lymphocytic Leukemia identifies a pro-migratory subpopulation and novel therapeutic target.
Blood 137(22), 3064-3078 (2021) [10.1182/blood.2020005964]
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EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4+ T cells in chronic lymphocytic leukemia.
Leukemia 35(8), 2311-2324 (2021) [10.1038/s41375-021-01136-1]
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Phosphoinositide 3-Kinase Signaling in the Tumor Microenvironment: What Do We Need to Consider When Treating Chronic Lymphocytic Leukemia With PI3K Inhibitors?
Frontiers in immunology 11, 595818 (2021) [10.3389/fimmu.2020.595818]
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Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections.
Blood advances 5(5), 1259 - 1272 (2021) [10.1182/bloodadvances.2020002949]
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Keratins determine network stress responsiveness in reconstituted actin-keratin filament systems.
Soft matter 17(14), 3954-3962 (2021) [10.1039/D0SM02261F]
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Publisher Correction: LifeTime and improving European healthcare through cell-based interceptive medicine.
Nature <London> 592(7852), E8 (2021) [10.1038/s41586-021-03287-8]
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EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia.
Leukemia 35(11), 3152-3162. (2021) [10.1038/s41375-021-01198-1]
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The age of adult pilocytic astrocytoma cells.
Oncogene 40(16), 2830-2841 (2021) [10.1038/s41388-021-01738-0]
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Increased B Cell activity with consumption of activated monocytes in severe COVID-19 patients.
European journal of immunology 51(6), 1449-1460 (2021) [10.1002/eji.202049163]
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IDO1-Targeted Therapy Does Not Control Disease Development in the Eµ-TCL1 Mouse Model of Chronic Lymphocytic Leukemia
Cancers 13(8), 1899 (2021) [10.3390/cancers13081899]
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Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas.
Leukemia 35(7), 2002-2016 (2021) [10.1038/s41375-021-01251-z]
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CATCH: A Prospective Precision Oncology Trial in Metastatic Breast Cancer.
JCO precision oncology 5(5), 676 - 686 (2021) [10.1200/PO.20.00248]
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Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.
Neuro-Oncology 23(12), 2028-2041 (2021) [10.1093/neuonc/noab127]
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Integrative Ranking of Enhancer Networks Facilitates the Discovery of Epigenetic Markers in Cancer.
Frontiers in genetics 12, 664654 (2021) [10.3389/fgene.2021.664654]
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Impact of IL-1? and the IL-1R antagonist on relapse risk and survival in AML patients undergoing immunotherapy for remission maintenance
OncoImmunology 10(1), 1944538 (2021) [10.1080/2162402X.2021.1944538]
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The pediatric precision oncology INFORM registry: clinical outcome and benefit for patients with very high-evidence targets.
Cancer discovery 11(11), 2764-2779 (2021) [10.1158/2159-8290.CD-21-0094]
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Autologous culture model of nodal B-cell lymphoma identifies ex vivo determinants of response to bispecific antibodies.
Blood advances 5(23), 5060-5071 (2021) [10.1182/bloodadvances.2021005400]
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Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation.
Nature Communications 12(1), 6963 (2021) [10.1038/s41467-021-27161-3]
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Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity.
Immunity 54(12), 2825-2841.e10 (2021) [10.1016/j.immuni.2021.11.004]
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Editorial: New Insights Into the Complexity of Tumor Immunology in B-Cell Malignancies: Disease Biology and Signaling.
Frontiers in oncology 11, 820984 (2021) [10.3389/fonc.2021.820984]
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