Synthesis Club
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A General Entry to Ganoderma Meroterpenoids: Synthesis of Applanatumol E, H, and I, Lingzhilactone B, Meroapplanin B, and Lingzhiol
A. Rode, N. Müller, O. Kováč, K. Wurst, T. Magauer Org. Lett. 2024, 26, 9017–9021.
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Total Synthesis of the Hexacyclic Sesterterpenoid Niduterpenoid B via Structural Reorganization Strategy
Xue, Y.; Hou, S.-H.; Zhang, X.; Zhang, F.-M.; Zhang, X.-M.; Tu, Y.-Q. J. Am. Chem. Soc. 2024, 146, 254454–25450.
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Total Syntheses of Borolithochromes A, D and G
K. Kirita, H. Matsumoto, G. Endo, S. Hosokawa Angew. Chem. Int. Ed. 2024, 63, e202400586
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Total Synthesis of the Euphorbia Diterpenoid Pepluacetal
Liu, M.; Wu, C.; Xie, X.; Li, H.; She, X. Angew. Chem. Int. Ed. 2024, e202400943.
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Enantioselective Synthesis of Pactamycin, a Complex Antitumor Antibiotic
Justin T. Malinowki, Robert J. Sharpe, Jeffrey S. Johnson Science, 2013, 340, 180–182.
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Concise Total Synthesis of Complanadine A
D. Ma, B. S. Martin, K. S. Gallagher, T. Saito, and M. Dai Synthesis 2024, 56, 107-117; J. Am. Chem. Soc. 2021, 143, 16383–16387.
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A concise synthesis of tetrodotoxin
Konrad, D.B., Rühmann, K., Ando, H., Hetzler, B.E., Strassner, N., Houk, K.N., Matsuura, B.S., Trauner, D. Science, 2022, 377, 411–415.
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Navigating Excess Complexity: Total Synthesis of Daphenylline
Wright, BB. A., Regni, A., Chaisan, N., Sarpong, R. J. Am. Chem. Soc. 2024, 146, 1813–1818.
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Asymmetric Total Syntheses of (–)- and (+)-Strychnine and the Wieland–Gumlich Aldehyde
Steven D. Knight, Larry E. Overman, Garry Pairaudeau J. Am. Chem. Soc. 1995, 117, 5776–5788.
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Total Synthesis of Aleutianamine
Hao Yu, Zachary P. Sercel, Samir P. Rezgui, Jonathan Farhi, Scott C. Virgil, Brian M. Stoltz J. Am. Chem. Soc. 2023, 145, 25533–25537.
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Total Synthesis of Metaphanine and Oxoepistephamiersine
Ya-Kui Sun, Jin-Bao Qiao, Yu-Meng Xin, Qin Zhou, Zhi-Hua Ma, Hui Shao, Yu-Ming Zhao Angew. Chem. Int. Ed. 2023, 62, e202310917.
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Asymmetric Total Synthesis of Illisimonin A
Etling, C., Tedesco, G., Di Marco, A., Kalesse, M. J. Am. Chem. Soc. 2023, 145, 7021–7029.
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A Convergent Total Synthesis of (+)-Ineleganolide
Gross, Benjamin M.; Han, Seo-Jung; Virgil, Scott C.;Stoltz, Brian M. J. Am. Chem. Soc. 2023, 145, 7763–7767.
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Enantioselective total synthesis of sacrolide A
T. Mohri, Y. Ogura, R. Towada, S. Kuwahara Tetrahedrom Lett. 2017, 58, 4011-4013.
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Total Synthesis of Strempeliopidine and Non-Natural Stereoisomers through a Convergent Petasis Borono–Mannich Reaction
Rand, A.W.; Gonzalez, K.J.; Reimann, C.E.; Virgil, S.C; Stoltz, B.M. J. Am. Chem. Soc. 2023, 145, 7278–7287.
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Enantioselective Total Synthesis of (−)-Caulamidine A
Zhouyang Zhu and Thomas J. Maimone J. Am. Chem. Soc. 2023, 145, 14215–14220.
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Total Syntheses of (+)-Waixenicin A, (+)-9-Deacetoxy-14,15-deepoxyxeniculin, and (−)-Xeniafaraunol A
Steinborn, C., Huber, T., Lichtenegger, J., Plangger, I., Wurst, K., & Magauer, T. J. Am. Chem. Soc. 2023, 145, 11811–11817.
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Synthesis of Eupalinilide E, a Promoter of Human Hematopoietic Stem and Progenitor Cell Expansion
Johnson, T.C., Chin, M.R., Han, T., Shen, J.P., Rana, T., Siegel, D. J. Am. Chem. Soc. 2016, 138, 6068–6073
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Enantioselective Total Synthesis of Lycopodine
Hua Yang, Rich G. Carter and Lev N. Zakharov J. Am. Chem. Soc. 2008, 130, 9238–9239.
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Total Synthesis and Structure Assignment of (+)-Hexacyclinol
Porco, J.A., Jr.; Su, S.; Lei, X.; Bardhan, S.; Rychnovsky, S.D. Angew. Chem. Int. Ed. 2006, 45, 5790 – 5792.
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Total Synthesis of Vilmoraconitine
Ji, J; Chen, J; Qin, S; Li, W; Zhao, J; Li, G; Song, H; Liu, X-Y; Qin, Y J. Am. Chem. Soc. 2023, 145, 3903–3908.
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Total Synthesis of Yuzurine-type Alkaloid Daphgraciline
Li, L.-X.; Min, L.; Yao, T.-B.; Ji, S.-X.; Qiao, C.; Tian, P.-L.; Sun, J.; Li, C.-C. J. Am. Chem. Soc. 2022, 144, 18823 – 18828.
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The First Asymmetric Synthesis of a Lycorine Alkaloid. Total Synthesis of (+)-1-Deoxylycorine
A. G. Schultz, M. A. Holoboski, M. S. Smyth J. Am. Chem. Soc. 1993, 115, 7904–7905.
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Scalable Total Synthesis of (–)-Vinigrol
Xuerong Yu, Lianghong Xiao, Zechun Wang, Tuoping Luo J. Am. Chem. Soc. 2019, 141, 3440–13443.
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Highly Efficient Total Synthesis of the Marine Natural Products (+)-Avarone, (+)-Avarol, (−)-Neoavarone, (−)-Neoavarol and (+)-Aureol
J. Sakurai, T. Oguchi, K. Watanabe, H. Abe, S. Kanno, M. Ishikawa, and T. Katoh Chem. Eur. J. 2008, 14, 829 – 837.
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A 16-step synthesis of the isoryanodane diterpene (+)-perseanol
Han, A.; Tao, Y.; Resiman, S. E. Nature 2019, 573, 563–568.
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The Furan Shuffling Hypothesis: A Biogenetic Proposal for Eremophilane Sesquiterpenoids
N. Lardon, R. Liffert, A. Linden, K. Gademann Angew. Chem. Int. Ed. 2019, 58, 7004–7007.
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Second-generation synthesis of salvinorin A
H. Hagiwara, Y. Suka, T. Nojima, T. Hoshi, T. Suzuki Tetrahedron 2009, 65, 4820–4825.