Publications 2024
Bortezomib before and after high-dose therapy in transplant-eligible patients with newly diagnosed multiple myeloma: Long-term overall survival after more than 10 years of follow-up from the phase III HOVON-65/GMMG-HD4 trial.
HemaSphere 8(11), e70052 (2024) [10.1002/hem3.70052]
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The prognostic impact of CDKN2A/B hemizygous deletions in IDH-mutant glioma.
Neuro-Oncology nn, nn (2024) [10.1093/neuonc/noae238]
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Meningiomas: Sex-Specific Differences and Prognostic Implications of a Chromosome X Loss.
Neuro-Oncology nn, nn (2024) [10.1093/neuonc/noae239]
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Efficacy and Safety of Autologous Stem Cell Transplantation in First-Line Treatment and at Relapse in Elderly Patients with Multiple Myeloma.
Oncology nn, nn (2024) [10.1159/000541541]
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Outcomes with intensive treatment for acute myeloid leukemia: an analysis of two decades of data from the HARMONY Alliance.
Haematologica nn, nn (2024) [10.3324/haematol.2024.285805]
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Comparing Patient?s Confidence in Clinical Capabilities in Urology: Large Language Models Versus Urologists
European urology open science 70, 91 - 98 (2024) [10.1016/j.euros.2024.10.009]
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STIL overexpression shortens lifespan and reduces tumor formation in mice.
PLoS Genetics 20(10), e1011460 - (2024) [10.1371/journal.pgen.1011460]
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Unleashing the strengths of unlabelled data in deep learning-assisted pan-cancer abdominal organ quantification: the FLARE22 challenge.
The lancet / Digital health 6(11), e815 - e826 (2024) [10.1016/S2589-7500(24)00154-7]
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Patterns of progression in a contemporary cohort of 447 patients with smoldering multiple myeloma.
Blood cancer journal 14(1), 176 (2024) [10.1038/s41408-024-01159-8]
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EASIX-guided risk stratification for complications and outcome after CAR T-cell therapy with ide-cel in relapsed/refractory multiple myeloma.
Journal for ImmunoTherapy of Cancer 12(10), e009220 (2024) [10.1136/jitc-2024-009220]
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Glucocorticoids induce a maladaptive epithelial stress response to aggravate acute kidney injury.
Science translational medicine 16(767), eadk5005 (2024) [10.1126/scitranslmed.adk5005]
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Plain language summary of isatuximab plus carfilzomib, lenalidomide, and dexamethasone for the treatment of people with high-risk newly diagnosed multiple myeloma.
Future oncology nn, nn (2024) [10.1080/14796694.2024.2402639]
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Measurable Residual Disease Monitoring in AML With FLT3-ITD Treated With Intensive Chemotherapy Plus Midostaurin.
Blood advances nn, nn (2024) [10.1182/bloodadvances.2024013758]
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Integration of Transcriptomics, Proteomics and Loss-of-function Screening Reveals WEE1 as a Target for Combination with Dasatinib against Proneural Glioblastoma.
Cancer letters 605, 217265 (2024) [10.1016/j.canlet.2024.217265]
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Bicenter validation of a risk model for the preoperative prediction of extraprostatic extension of localized prostate cancer combining clinical and multiparametric MRI parameters.
World journal of urology 42(1), 530 (2024) [10.1007/s00345-024-05232-6]
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Developing survival prediction models in colorectal cancer using epigenome-wide DNA methylation data from whole blood.
npj precision oncology 8(1), 191 (2024) [10.1038/s41698-024-00689-5]
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Longitudinal assessment of established risk stratification models in patients with monoclonal gammopathy of undetermined significance.
Blood cancer journal 14(1), 148 (2024) [10.1038/s41408-024-01126-3]
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Loss over 5% of chromosome 1p is a clinically relevant and applicable cut-off for increased risk of recurrence in meningioma.
Acta neuropathologica 148(1), 17 (2024) [10.1007/s00401-024-02777-z]
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Gender-specific differences in bariatric surgery: epidemiology, treatment and results. |[Geschlechtsspezifische Unterschiede in der Adipositaschirurgie: Epidemiologie, Therapie und Ergebnisse].
Die Chirurgie 95(9), 721?729 (2024) [10.1007/s00104-024-02149-z]
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How do deep-learning models generalize across populations? Cross-ethnicity generalization of COPD detection.
Insights into imaging 15(1), 198 (2024) [10.1186/s13244-024-01781-x]
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Clinical Presentation, Management, and Outcome in Neurolymphomatosis: A Systematic Review.
Neurology 103(4), e209698 (2024) [10.1212/WNL.0000000000209698]
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Detection of myeloma-associated osteolytic bone lesions with energy-integrating and photon-counting detector CT .[Erkennung myelomassoziierter osteolytischer Knochenläsionen mit energieintegrierender und photonenzählender Detektor-Computertomographie].
Die Radiologie nn, nn (2024) [10.1007/s00117-024-01344-7]
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Refinement of the prognostic impact of somatic CEBPA bZIP domain mutations in acute myeloid leukemia: Results of the AML Study Group (AMLSG).
HemaSphere 8(7), e123 (2024) [10.1002/hem3.123]
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Quantitative Integrative Survival Prediction in Multiple Myeloma Patients Treated With Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation.
JCO precision oncology 8(8), e2300613 (2024) [10.1200/PO.23.00613]
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Rearrangements involving 11q23.3/KMT2A in adult AML: mutational landscape and prognostic implications - a HARMONY study.
Leukemia 38(9), 1929-1937 (2024) [10.1038/s41375-024-02333-4]
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Prostate cancer risk assessment and avoidance of prostate biopsies using fully automatic deep learning in prostate MRI: comparison to PI-RADS and integration with clinical data in nomograms.
European radiology 34, 7909?7920 (2024) [10.1007/s00330-024-10818-0]
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The German sickle cell disease registry reveals a surprising risk of acute splenic sequestration and an increased transfusion requirement in patients with compound heterozygous sickle cell disease HbS/?-thalassaemia and no or low HbA expression.
European journal of haematology 113(4), 501-509 (2024) [10.1111/ejh.14259]
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Interaction Difference Hypothesis Test for Prediction Models
Machine learning and knowledge extraction 6(2), 1298 - 1322 (2024) [10.3390/make6020061]
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Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours.
British journal of cancer 131(4), 763-777 (2024) [10.1038/s41416-024-02740-5]
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Molecular Long-Term Analysis of the GMMG-HD4 Trial in Multiple Myeloma-Patterns of Association of Chromosomal Aberrations with Response and Proliferation Determining Survival in Selecting Treatments in View of Limited Resources in Low- and Middle-Income Countries.
International journal of molecular sciences 25(12), 6431 (2024) [10.3390/ijms25126431]
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Large-scale external validation and meta-analysis of gene methylation biomarkers in tumor tissue for colorectal cancer prognosis.
EBioMedicine 105, 105223 (2024) [10.1016/j.ebiom.2024.105223]
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CD8+ CD28- regulatory T cells after induction therapy predict progression-free survival in myeloma patients: results from the GMMG-HD6 multicenter phase III study.
Leukemia 38(7), 1621-1625 (2024) [10.1038/s41375-024-02290-y]
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Simulation study to evaluate when Plasmode simulation is superior to parametric simulation in estimating the mean squared error of the least squares estimator in linear regression.
PLOS ONE 19(5), e0299989 - (2024) [10.1371/journal.pone.0299989]
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Risk-adjusted Screening for Prostate Cancer-Defining the Low-risk Group by Data from the PROBASE Trial.
European urology nn, nn (2024) [10.1016/j.eururo.2024.04.030]
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Reproducible Radiomics Features from Multi-MRI-Scanner Test-Retest-Study: Influence on Performance and Generalizability of Models.
Journal of magnetic resonance imaging nn, nn (2024) [10.1002/jmri.29442]
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Low tumor interleukin-1? expression predicts a limited effect of adjuvant platinum-based chemotherapy for patients with completely resected lung adenocarcinoma: An identification and validation study.
Pulmonology nn, nn (2024) [10.1016/j.pulmoe.2024.03.003]
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Addition of inflammation-related biomarkers to the CAIDE model for risk prediction of all-cause dementia, Alzheimer's disease and vascular dementia in a prospective study.
Immunity & ageing 21(1), 23 (2024) [10.1186/s12979-024-00427-2]
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Neurologic Complications of the Central Nervous System after Allogeneic Stem Cell Transplantation: The Role of Transplantation-Associated Thrombotic Microangiopathy as a Potential Underreported Cause.
Transplantation and cellular therapy 30(6), 586.e1-586.e11 (2024) [10.1016/j.jtct.2024.03.017]
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Capturing COPD heterogeneity: anomaly detection and parametric response mapping comparison for phenotyping on chest computed tomography.
Frontiers in medicine 11, 1360706 (2024) [10.3389/fmed.2024.1360706]
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Would initiating colorectal cancer screening from age of 45 be cost-effective in Germany? An individual-level simulation analysis.
Frontiers in Public Health 12, 1307427 (2024) [10.3389/fpubh.2024.1307427]
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Artificial intelligence-based, volumetric assessment of the bone marrow metabolic activity in [18F]FDG PET/CT predicts survival in multiple myeloma.
European journal of nuclear medicine and molecular imaging 51(8), 2293-2307 (2024) [10.1007/s00259-024-06668-z]
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Cytomegalovirus immunoglobulin serology prevalence in patients with newly diagnosed multiple myeloma treated within the GMMG-MM5 phase III trial.
Hematology 29(1), 2320006 (2024) [10.1080/16078454.2024.2320006]
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Statistical plasmode simulations-Potentials, challenges and recommendations.
Statistics in medicine 43(9), 1804-1825 (2024) [10.1002/sim.10012]
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Understanding metric-related pitfalls in image analysis validation.
Nature methods 21(2), 182 - 194 (2024) [10.1038/s41592-023-02150-0]
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Metrics reloaded: recommendations for image analysis validation.
Nature methods 21(2), 195 - 212 (2024) [10.1038/s41592-023-02151-z]
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A diagnostic phase III/IV seamless design to investigate the diagnostic accuracy and clinical effectiveness using the example of HEDOS and HEDOS II.
Statistical methods in medical research 33(3), 433-448 (2024) [10.1177/09622802241227951]
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Differential Immunoexpression of Inhibitory Immune Checkpoint Molecules and Clinicopathological Correlates in Keratoacanthoma, Primary Cutaneous Squamous Cell Carcinoma and Metastases.
Acta dermato-venereologica 104, adv13381 - (2024) [10.2340/actadv.v104.13381]
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Elotuzumab, lenalidomide, bortezomib, dexamethasone, and autologous haematopoietic stem-cell transplantation for newly diagnosed multiple myeloma (GMMG-HD6): results from a randomised, phase 3 trial.
The lancet / Haematology 11(2), e101 - e113 (2024) [10.1016/S2352-3026(23)00366-6]
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Clinical evaluation of complete remission (CR) with partial hematologic recovery (CRh) in acute myeloid leukemia: a report of 7235 patients from seven cohorts.
Leukemia 38(2), 389-392 (2024) [10.1038/s41375-024-02143-8]
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Endothelial Activation and Stress Index (EASIX) to predict mortality after allogeneic stem cell transplantation: a prospective study.
Journal for ImmunoTherapy of Cancer 12(1), e007635 (2024) [10.1136/jitc-2023-007635]
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Frequency and Prognostic Value of Circulating Tumor Cells in Cancer of Unknown Primary.
Clinical chemistry 70(1), 297 - 306 (2024) [10.1093/clinchem/hvad180]
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Prediction of disease severity in COPD: a deep learning approach for anomaly-based quantitative assessment of chest CT.
European radiology 34(7), 4379-4392 (2024) [10.1007/s00330-023-10540-3]
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Robust incorporation of historical information with known type I error rate inflation.
Biometrical journal 66(1), e2200322 (2024) [10.1002/bimj.202200322]
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Predictors of early morbidity and mortality in newly diagnosed multiple myeloma: data from five randomized, controlled, phase III trials in 3700 patients.
Leukemia 38(3), 640-647 (2024) [10.1038/s41375-023-02105-6]
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Onset time and characteristics of post-procedural bleeding after endoscopic resection of colorectal lesions: a multicenter retrospective study.
Digestive diseases 42(1), 78-86 (2024) [10.1159/000534109]
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CpG-biomarkers in tumor tissue and prediction models for the survival of colorectal cancer: a systematic review and external validation study.
Critical reviews in oncology, hematology 193, 104199 (2024) [10.1016/j.critrevonc.2023.104199]
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Multiparametric Magnetic Resonance Imaging in Prostate Cancer Screening at the Age of 45 Years: Results from the First Screening Round of the PROBASE Trial.
European urology 85(2), 105-111 (2024) [10.1016/j.eururo.2023.09.027]
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Isatuximab, Carfilzomib, Lenalidomide, and Dexamethasone for the Treatment of High-Risk Newly Diagnosed Multiple Myeloma.
Journal of clinical oncology 42(1), 26-37 (2024) [10.1200/JCO.23.01696]
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Simulating and reporting frequentist operating characteristics of clinical trials that borrow external information: Towards a fair comparison in case of one-arm and hybrid control two-arm trials.
Pharmaceutical statistics 23(1), 4-19 (2024) [10.1002/pst.2334]
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Weakly Supervised MRI Slice-Level Deep Learning Classification of Prostate Cancer Approximates Full Voxel- and Slice-Level Annotation: Effect of Increasing Training Set Size.
Journal of magnetic resonance imaging 59(4), 1409-1422 (2024) [10.1002/jmri.28891]
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Fludarabine, cytarabine, and idarubicin with or without venetoclax in patients with relapsed/refractory acute myeloid leukemia.
Haematologica 109(1), 72-83 (2024) [10.3324/haematol.2023.282912]
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Coping with Information Loss and the Use of Auxiliary Sources of Data: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions
Statistics in biopharmaceutical research 16(2), 141-157 (2024) [10.1080/19466315.2023.2211023]
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Bovine meat and milk factor protein expression in tumor-free mucosa of colorectal cancer patients coincides with macrophages and might interfere with patient survival.
Molecular oncology 18(5), 1076-1092 (2024) [10.1002/1878-0261.13390]
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