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Seystahl, K. ; Hentschel, B. ; Loew, S. ; Gramatzki, D. ; Felsberg, J. ; Herrlinger, U. ; Westphal, M. ; Schackert, G. ; Thon, N. ; Tatagiba, M. ; Pietsch, T. ; Reifenberger, G. ; Löffler, M. ; Wick, W. ; Weller, M. Bevacizumab versus alkylating chemotherapy in recurrent glioblastoma
Journal of cancer research and clinical oncology 146 (3 ), 659-670 (2019 ) [10.1007/s00432-019-03086-9 ] 2019
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Nassiri, F. ; Aldape, K. ; Alhuwalia, M. ; Brastianos, P. ; Ducray, F. ; Galldiks, N. ; Kim, A. ; Lamszus, K. ; Mitchell, D. ; Nabors, L. B. ; Nam, D.-H. ; Natsume, A. ; Ng, H.-K. ; Niclou, S. ; Sahm, F. ; Short, S. ; Walsh, K. ; Wick, W. ; Zadeh, G. Highlights of the inaugural ten - the launch of Neuro-Oncology Advances.
Neuro-oncology advances 1 (1 ), vdz016 (2019 ) [10.1093/noajnl/vdz016 ] 2019
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Wick, W. (First author) ; Kessler, T. (Last author) Vielversprechende Daten erst 2020 erwartet
Im Focus Onkologie 22 (4 ), 85-86 (2019 ) [doi.org/10.1007/s15015-019-0153-z ] 2019
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Kessler, T. ; Wick, W. Stellenwert molekularer Analysen von Hirntumoren in der Routine
Im Focus Onkologie 4 , 23.April 2019 (2019 ) 2019
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Furtner, J. ; Genbrugge, E. ; Gorlia, T. ; Bendszus, M. ; Nowosielski, M. ; Golfinopoulos, V. ; Weller, M. ; van den Bent, M. J. ; Wick, W. ; Preusser, M. Temporal muscle thickness is an independent prognostic marker in patients with progressive glioblastoma: translational imaging analysis of the EORTC 26101 trial.
Neuro-Oncology 21 (12 ), 1587 - 1594 (2019 ) [10.1093/neuonc/noz131 ] 2019
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Portela, M. ; Venkataramani, V. ; Fahey-Lozano, N. ; Seco, E. ; Losada-Perez, M. ; Winkler, F. ; Casas-Tintó, S. Glioblastoma cells vampirize WNT from neurons and trigger a JNK/MMP signaling loop that enhances glioblastoma progression and neurodegeneration.
PLoS biology 17 (12 ), e3000545 - (2019 ) [10.1371/journal.pbio.3000545 ] 2019
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Hilf, N. ; Kuttruff-Coqui, S. ; Frenzel, K. ; et al Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma.
Nature <London> 566 (7745 ), E13 - E13 (2019 ) [10.1038/s41586-019-0959-z ] 2019
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Jung, E. (First author) ; Alfonso, J. ; Osswald, M. ; Monyer, H. ; Wick, W. ; Winkler, F. (Last author) Emerging intersections between neuroscience and glioma biology
Nature neuroscience 22 (12 ), 1951 - 1960 (2019 ) [10.1038/s41593-019-0540-y ] 2019
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Al-Ali, R. ; Bauer, K. ; Park, J.-W. ; Al Abdulla, R. ; Fermi, V. ; von Deimling, A. ; Herold-Mende, C. ; Mallm, J.-P. ; Herrmann, C. ; Wick, W. ; Turcan, ?. Single-nucleus chromatin accessibility reveals intratumoral epigenetic heterogeneity in IDH1 mutant gliomas.
Acta Neuropathologica Communications 7 (1 ), 201 (2019 ) [10.1186/s40478-019-0851-y ] 2019
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Demirdizen, E. ; Spiller-Becker, M. ; Förtsch, A. ; Wilhelm, A. ; Corless, S. ; Bade, D. ; Bergner, A. ; Hessling, B. ; Erhardt, S. Localization of Drosophila CENP-A to non-centromeric sites depends on the NuRD complex.
Nucleic acids research 47 (22 ), 11589-11608 (2019 ) [10.1093/nar/gkz962 ] 2019
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Coomans, M. B. ; Dirven, L. ; Aaronson, N. K. ; Baumert, B. G. ; Van Den Bent, M. ; Bottomley, A. ; Brandes, A. A. ; Chinot, O. ; Coens, C. ; Gorlia, T. ; Herrlinger, U. ; Keime-Guibert, F. ; Malmström, A. ; Martinelli, F. ; Stupp, R. ; Talacchi, A. ; Weller, M. ; Wick, W. ; Reijneveld, J. C. ; Taphoorn, M. J. B. Symptom clusters in newly diagnosed glioma patients: which symptom clusters are independently associated with functioning and global health status?
Neuro-Oncology 21 (11 ), 1447 - 1457 (2019 ) [10.1093/neuonc/noz118 ] 2019
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Sonner, J. (First author) ; Keil, M. (First author) ; Falk-Paulsen, M. ; Mishra, N. ; Rehman, A. ; Kramer, M. ; Deumelandt, K. ; Röwe, J. ; Sanghvi, K. ; Wolf, L. ; von Landenberg, A. ; Wolff, H. ; Bharti, R. ; Oezen, I. ; Lanz, T. ; Wanke, F. ; Tang, Y. ; Brandao, I. ; Mohapatra, S. R. ; Epping, L. ; Grill, A. ; Röth, R. ; Niesler, B. ; Meuth, S. G. ; Opitz, C. ; Okun, J. G. ; Reinhardt, C. ; Kurschus, F. C. ; Wick, W. ; Bode, H. B. ; Rosenstiel, P. ; Platten, M. (Last author) Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology.
Nature Communications 10 (1 ), 4877 (2019 ) [10.1038/s41467-019-12776-4 ] 2019
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Schönenberger, S. ; Hendén, P. L. ; Simonsen, C. Z. ; Uhlmann, L. ; Klose, C. ; Pfaff, J. A. R. ; Yoo, A. J. ; Sørensen, L. H. ; Ringleb, P. A. ; Wick, W. ; Kieser, M. ; Möhlenbruch, M. A. ; Rasmussen, M. ; Rentzos, A. ; Bösel, J. Association of General Anesthesia vs Procedural Sedation With Functional Outcome Among Patients With Acute Ischemic Stroke Undergoing Thrombectomy: A Systematic Review and Meta-analysis.
The journal of the American Medical Association 322 (13 ), 1283 (2019 ) [10.1001/jama.2019.11455 ] 2019
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Schwarz, D. (First author) ; Niederle, T. ; Münch, P. ; Hielscher, T. ; Hassel, J. C. ; Schlemmer, H.-P. ; Platten, M. ; Winkler, F. ; Wick, W. ; Heiland, S. ; Delorme, S. ; Bendszus, M. ; Bäumer, P. ; Breckwoldt, M. (Last author) Susceptibility-weighted imaging in malignant melanoma brain metastasis.
Journal of magnetic resonance imaging 50 (4 ), 1251 - 1259 (2019 ) [10.1002/jmri.26692 ] 2019
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Schiff, D. ; van den Bent, M. ; Vogelbaum, M. A. ; Wick, W. ; Miller, C. R. ; Taphoorn, M. ; Pope, W. ; Brown, P. D. ; Platten, M. ; Jalali, R. ; Armstrong, T. ; Wen, P. Y. Recent Developments and Future Directions in Adult Lower-Grade Gliomas: Society for Neuro-Oncology (SNO) and European Association of Neuro-Oncology (EANO) Consensus.
Neuro-Oncology 21 (7 ), 837 - 853 (2019 ) [10.1093/neuonc/noz033 ] 2019
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Venkataramani, V. (First author) ; Tanev, D. I. ; Strahle, C. ; Studier-Fischer, A. ; Fankhauser, L. ; Kessler, T. ; Körber, C. ; Kardorff, M. ; Ratliff, M. ; Xie, R. ; Horstmann, H. ; Messer, M. ; Paik, S. P. ; Knabbe, J. ; Sahm, F. ; Kurz, F. T. ; Acikgöz, A. A. ; Herrmannsdörfer, F. ; Agarwal, A. ; Bergles, D. E. ; Chalmers, A. ; Miletic, H. ; Turcan, S. ; Mawrin, C. ; Hänggi, D. ; Liu, H.-K. ; Wick, W. ; Winkler, F. (Last author) ; Kuner, T. Glutamatergic synaptic input to glioma cells drives brain tumour progression.
Nature <London> 573 (7775 ), 532-538 (2019 ) [10.1038/s41586-019-1564-x ] 2019
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Isensee, F. (First author) ; Schell, M. ; Pflueger, I. ; Brugnara, G. ; Bonekamp, D. ; Neuberger, U. ; Wick, A. ; Schlemmer, H.-P. ; Heiland, S. ; Wick, W. ; Bendszus, M. ; Maier-Hein, K. H. ; Kickingereder, P. Automated brain extraction of multisequence MRI using artificial neural networks.
Human brain mapping 40 (17 ), 4952-4964 (2019 ) [10.1002/hbm.24750 ] 2019
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Hahn, A. ; Bode, J. ; Krüwel, T. ; Solecki, G. ; Heiland, S. ; Bendszus, M. ; Tews, B. ; Winkler, F. ; Breckwoldt, M. ; Kurz, F. T. Glioblastoma multiforme restructures the topological connectivity of cerebrovascular networks.
Scientific reports 9 (1 ), 11757 (2019 ) [10.1038/s41598-019-47567-w ] 2019
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Kollmer, J. ; Hilgenfeld, T. ; Ziegler, A. ; Saffari, A. ; Sam, G. ; Hayes, J. M. ; Pietsch, A. ; Jost, M. ; Heiland, S. ; Bendszus, M. ; Wick, W. ; Weiler, M. Quantitative MR neurography biomarkers in 5q-linked spinal muscular atrophy.
Neurology 93 (7 ), e653-e664 (2019 ) [10.1212/WNL.0000000000007945 ] 2019
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Le Rhun, E. ; Devos, P. ; Boulanger, T. ; Smits, M. ; Brandsma, D. ; Rudà, R. ; Furtner, J. ; Hempel, J.-M. ; Postma, T. J. ; Roth, P. ; Snijders, T. J. ; Winkler, F. ; Winklhofer, S. ; Castellano, A. ; Hattingen, E. ; Capellades, J. ; Gorlia, T. ; Van den Bent, M. ; Wen, P. Y. ; Bendszus, M. ; Weller, M. ; Cancer, E. O. f. R. a. T. o. (Collaboration Author) The RANO Leptomeningeal Metastasis Group proposal to assess response to treatment: lack of feasibility and clinical utility and a revised proposal.
Neuro-Oncology 21 (5 ), 648 - 658 (2019 ) [10.1093/neuonc/noz024 ] 2019
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Piechutta, M. ; Berghoff, A. S. New emerging targets in cancer immunotherapy: the role of Cluster of Differentiation 40 (CD40/TNFR5).
ESMO open 4 (Suppl 3 ), e000510 (2019 ) [10.1136/esmoopen-2019-000510 ] 2019
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Stichel, D. (First author) ; Schrimpf, D. ; Casalini, B. ; Meyer, J. ; Wefers, A. K. ; Sievers, P. ; Korshunov, A. ; Koelsche, C. ; Reuss, D. E. ; Reinhardt, A. ; Ebrahimi, A. ; Fernández-Klett, F. ; Kessler, T. ; Sturm, D. ; Ecker, J. ; Milde, T. ; Herold-Mende, C. ; Witt, O. ; Pfister, S. M. ; Wick, W. ; Jones, D. T. W. ; von Deimling, A. (Last author) ; Sahm, F. (Last author) Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions.
Acta neuropathologica 138 (5 ), 827-835 (2019 ) [10.1007/s00401-019-02039-3 ] 2019
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Sievers, P. (First author) ; Appay, R. ; Schrimpf, D. ; Stichel, D. ; Reuss, D. E. ; Wefers, A. K. ; Reinhardt, A. ; Coras, R. ; Ruf, V. C. ; Schmid, S. ; de Stricker, K. ; Boldt, H. B. ; Kristensen, B. W. ; Petersen, J. K. ; Ulhøi, B. P. ; Gardberg, M. ; Aronica, E. ; Hasselblatt, M. ; Brück, W. ; Bielle, F. ; Mokhtari, K. ; Lhermitte, B. ; Wick, W. ; Herold-Mende, C. ; Hänggi, D. ; Brandner, S. ; Giangaspero, F. ; Capper, D. ; Rushing, E. ; Wesseling, P. ; Pfister, S. M. ; Figarella-Branger, D. ; von Deimling, A. ; Sahm, F. ; Jones, D. (Last author) Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1.
Acta neuropathologica 138 (3 ), 497-504 (2019 ) [10.1007/s00401-019-02038-4 ] 2019
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Fischer, R. ; Padutsch, T. ; Bracchi-Ricard, V. ; Murphy, K. L. ; Martinez, G. F. ; Delguercio, N. ; Elmer, N. ; Sendetski, M. ; Diem, R. ; Eisel, U. L. M. ; Smeyne, R. J. ; Kontermann, R. E. ; Pfizenmaier, K. ; Bethea, J. R. Exogenous activation of tumor necrosis factor receptor 2 promotes recovery from sensory and motor disease in a model of multiple sclerosis.
Brain, behavior and immunity 81 , 247-259 (2019 ) [10.1016/j.bbi.2019.06.021 ] 2019
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Coomans, M. ; Dirven, L. ; K Aaronson, N. ; Baumert, B. G. ; van den Bent, M. ; Bottomley, A. ; Brandes, A. A. ; Chinot, O. ; Coens, C. ; Gorlia, T. ; Herrlinger, U. ; Keime-Guibert, F. ; Malmström, A. ; Martinelli, F. ; Stupp, R. ; Talacchi, A. ; Weller, M. ; Wick, W. ; Reijneveld, J. C. ; Taphoorn, M. J. B. ; Group, E. Q. o. L. G. a. t. E. B. T. (Collaboration Author) The added value of health-related quality of life as a prognostic indicator of overall survival and progression-free survival in glioma patients: a meta-analysis based on individual patient data from randomised controlled trials.
European journal of cancer 116 , 190 - 198 (2019 ) [10.1016/j.ejca.2019.05.012 ] 2019
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Binder, H. ; Willscher, E. ; Loeffler-Wirth, H. ; Hopp, L. ; Jones, D. T. W. ; Pfister, S. M. ; Kreuz, M. ; Gramatzki, D. ; Fortenbacher, E. ; Hentschel, B. ; Tatagiba, M. ; Herrlinger, U. ; Vatter, H. ; Matschke, J. ; Westphal, M. ; Krex, D. ; Schackert, G. ; Tonn, J. C. ; Schlegel, U. ; Steiger, H.-J. ; Wick, W. ; Weber, R. G. ; Weller, M. ; Loeffler, M. DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development.
Acta Neuropathologica Communications 7 (1 ), 59 (2019 ) [10.1186/s40478-019-0704-8 ] 2019
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Fairless, R. (First author) ; Williams, S. K. ; Diem, R. (Last author) Calcium-Binding Proteins as Determinants of Central Nervous System Neuronal Vulnerability to Disease.
International journal of molecular sciences 20 (9 ), 2146 (2019 ) [10.3390/ijms20092146 ] 2019
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Paramasivam, N. (First author) ; Hübschmann, D. (First author) ; Toprak, U. H. ; Ishaque, N. ; Neidert, M. ; Schrimpf, D. ; Stichel, D. ; Reuss, D. ; Sievers, P. ; Reinhardt, A. ; Wefers, A. K. ; Jones, D. T. W. ; Gu, Z. ; Werner, J. ; Uhrig, S. ; Wirsching, H.-G. ; Schick, M. ; Bewerunge-Hudler, M. ; Beck, K. ; Brehmer, S. ; Urbschat, S. ; Seiz-Rosenhagen, M. ; Hänggi, D. ; Herold-Mende, C. ; Ketter, R. ; Eils, R. ; Ram, Z. ; Pfister, S. M. ; Wick, W. ; Weller, M. ; Grossmann, R. ; von Deimling, A. ; Schlesner, M. (Last author) ; Sahm, F. (Last author) Mutational patterns and regulatory networks in epigenetic subgroups of meningioma.
Acta neuropathologica 138 (2 ), 295-308 (2019 ) [10.1007/s00401-019-02008-w ] 2019
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Hou, Y. ; Pinheiro, J. ; Sahm, F. ; Reuss, D. E. ; Schrimpf, D. ; Stichel, D. ; Casalini, B. ; Koelsche, C. ; Sievers, P. ; Wefers, A. K. ; Reinhardt, A. ; Ebrahimi, A. ; Fernández-Klett, F. ; Pusch, S. ; Meier, J. ; Schweizer, L. ; Paulus, W. ; Prinz, M. ; Hartmann, C. ; Plate, K. H. ; Reifenberger, G. ; Pietsch, T. ; Varlet, P. ; Pagès, M. ; Schüller, U. ; Scheie, D. ; de Stricker, K. ; Frank, S. ; Hench, J. ; Pollo, B. ; Brandner, S. ; Unterberg, A. ; Pfister, S. M. ; Jones, D. T. W. ; Korshunov, A. ; Wick, W. ; Capper, D. ; Blümcke, I. ; von Deimling, A. (Last author) ; Bertero, L. Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA.
Acta neuropathologica 137 (5 ), 837 - 846 (2019 ) [10.1007/s00401-019-01969-2 ] 2019
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Nowosielski, M. (First author) ; Gorlia, T. ; Bromberg, J. E. C. ; Sahm, F. ; Harting, I. ; Kickingereder, P. ; Brandes, A. A. ; Taphoorn, M. J. B. ; Taal, W. ; Domont, J. ; Idbaih, A. ; Campone, M. ; Clement, P. M. ; Weller, M. ; Fabbro, M. ; Le Rhun, E. ; Platten, M. ; Golfinopoulos, V. ; van den Bent, M. J. ; Bendszus, M. ; Wick, W. (Last author) Imaging necrosis during treatment is associated with worse survival in EORTC 26101 study.
Neurology 92 (24 ), e2754-e2763 (2019 ) [10.1212/WNL.0000000000007643 ] 2019
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Solecki, G. M. (First author) ; Osswald, M. ; Weber, D. ; Glock, M. ; Ratliff, M. ; Müller, H.-J. ; Krieter, O. ; Kienast, Y. ; Wick, W. ; Winkler, F. (Last author) Differential Effects of Ang-2/VEGF-A Inhibiting Antibodies in Combination with Radio- or Chemotherapy in Glioma.
Cancers 11 (3 ), 314 (2019 ) [10.3390/cancers11030314 ] 2019
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Joos, S. (First author) ; Nettelbeck, D. ; Reil-Held, A. ; Engelmann, K. ; Moosmann, A. ; Eggert, A. ; Hiddemann, W. ; Krause, M. ; Peters, C. ; Schuler, M. ; Schulze-Osthoff, K. ; Serve, H. ; Wick, W. ; Puchta, J. ; Baumann, M. (Last author) German Cancer Consortium (DKTK) - A national consortium for translational cancer research.
Molecular oncology 13 (3 ), 535 - 542 (2019 ) [10.1002/1878-0261.12430 ] 2019
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Korshunov, A. (First author) ; Casalini, B. ; Chavez, L. ; Hielscher, T. ; Sill, M. ; Ryzhova, M. ; Sharma, T. ; Schrimpf, D. ; Stichel, D. ; Capper, D. ; Reuss, D. E. ; Sturm, D. ; Absalyamova, O. ; Golanov, A. ; Lambo, S. ; Bewerunge-Hudler, M. ; Lichter, P. ; Herold-Mende, C. ; Wick, W. ; Pfister, S. ; Kool, M. ; Jones, D. ; von Deimling, A. ; Sahm, F. (Last author) Integrated molecular characterization of IDH-mutant glioblastomas.
Neuropathology & applied neurobiology 45 (2 ), 108 - 118 (2019 ) [10.1111/nan.12523 ] 2019
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Herrlinger, U. ; Tzaridis, T. ; Mack, F. ; Steinbach, J. P. ; Schlegel, U. ; Sabel, M. ; Hau, P. ; Kortmann, R.-D. ; Krex, D. ; Grauer, O. ; Goldbrunner, R. ; Schnell, O. ; Bähr, O. ; Uhl, M. ; Seidel, C. ; Tabatabai, G. ; Kowalski, T. ; Ringel, F. ; Schmidt-Graf, F. ; Suchorska, B. ; Brehmer, S. ; Weyerbrock, A. ; Renovanz, M. ; Bullinger, L. ; Galldiks, N. ; Vajkoczy, P. ; Misch, M. ; Vatter, H. ; Stuplich, M. ; Schäfer, N. ; Kebir, S. ; Weller, J. ; Schaub, C. ; Stummer, W. ; Tonn, J.-C. ; Simon, M. ; Keil, V. C. ; Nelles, M. ; Urbach, H. ; Coenen, M. ; Wick, W. ; Weller, M. ; Fimmers, R. ; Schmid, M. ; Hattingen, E. ; Pietsch, T. ; Coch, C. ; Glas, M. ; Society, N. W. G. o. t. G. C. (Collaboration Author) Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.
The lancet <London> 393 (10172 ), 678 - 688 (2019 ) [10.1016/S0140-6736(18)31791-4 ] 2019
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Chiblak, S. (First author) ; Tang, Z. ; Lemke, D. ; Knoll, M. ; Dokic, I. ; Warta, R. ; Moustafa, M. ; Mier, W. ; Brons, S. ; Rapp, C. ; Muschal, S. ; Seidel, P. ; Bendzsus, M. ; Adeberg, S. ; Wiestler, O. D. ; Haberkorn, U. ; Debus, J. ; Herold-Mende, C. ; Wick, W. ; Abdollahi, A. (Last author) Carbon irradiation overcomes glioma radioresistance by eradicating stem cells and forming an antiangiogenic and immunopermissive niche.
JCI insight 4 (2 ), e123837 (2019 ) [10.1172/jci.insight.123837 ] 2019
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Wick, W. (Last author) Neue Behandlungsoptionen bei GliomenNew treatment options for gliomas
Der Onkologe 25 (1 ), 60 - 66 (2019 ) [10.1007/s00761-018-0479-8 ] 2019
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Breckwoldt, M. (First author) ; Bode, J. ; Sahm, F. ; Krüwel, T. ; Solecki, G. ; Hahn, A. ; Wirthschaft, P. ; Berghoff, A. S. ; Haas, M. ; Venkataramani, V. ; von Deimling, A. ; Wick, W. ; Herold-Mende, C. ; Heiland, S. ; Platten, M. ; Bendszus, M. ; Kurz, F. T. ; Winkler, F. ; Tews, B. (Last author) Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease.
Frontiers in neuroscience 12 , 1004 (2019 ) [10.3389/fnins.2018.01004 ] 2019
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Hilf, N. ; Kuttruff-Coqui, S. ; Frenzel, K. ; et al Actively personalized vaccination trial for newly diagnosed glioblastoma.
Nature <London> 565 (7738 ), 240 - 245 (2019 ) [10.1038/s41586-018-0810-y ] 2019
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Eisemann, T. (First author) ; Costa, B. M. ; Harter, P. ; Wick, W. ; Mittelbronn, M. ; Angel, P. ; Peterziel, H. (Last author) Podoplanin expression is a prognostic biomarker but may be dispensable for the malignancy of glioblastoma.
Neuro-Oncology 21 (3 ), 326-336 (2019 ) [10.1093/neuonc/noy184 ] 2019
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Berberich, A. (First author) ; Kessler, T. ; Thome, C. ; Pusch, S. ; Hielscher, T. ; Sahm, F. ; Oezen, I. ; Schmitt, L.-M. ; Ciprut, S. ; Hucke, N. ; Rübmann, P. ; Fischer, M. ; Lemke, D. ; Breckwoldt, M. ; von Deimling, A. ; Bendszus, M. ; Platten, M. ; Wick, W. (Last author) Targeting resistance against the MDM2 inhibitor RG7388 in glioblastoma cells by the MEK inhibitor trametinib.
Clinical cancer research 25 (1 ), 253-265 (2019 ) [10.1158/1078-0432.CCR-18-1580 ] 2019
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Wick, W. (First author) ; Dettmer, S. ; Berberich, A. ; Kessler, T. ; Karapanagiotou-Schenkel, I. ; Wick, A. ; Winkler, F. ; Pfaff, E. ; Brors, B. ; Debus, J. ; Unterberg, A. ; Bendszus, M. ; Herold-Mende, C. ; Eisenmenger, A. ; von Deimling, A. ; Jones, D. ; Pfister, S. ; Sahm, F. ; Platten, M. (Last author) N2M2 (NOA20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma.
Neuro-Oncology 21 (1 ), 95-105 (2019 ) [10.1093/neuonc/noy161 ] 2019
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