Publikationen
Affinity-independent memory B cell origin of the early antibody-secreting cell response in naive individuals upon SARS-CoV-2 vaccination.
Immunity 57(9), 2191-2201.e5 (2024) [10.1016/j.immuni.2024.07.023]
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A safe and potentiated multi-type HPV L2-E7 nanoparticle vaccine with combined prophylactic and therapeutic activity.
npj vaccines 9(1), 119 (2024) [10.1038/s41541-024-00914-z]
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Full-length MSP1 is a major target of protective immunity after controlled human malaria infection.
Life science alliance 7(8), e202301910 - (2024) [10.26508/lsa.202301910]
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Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein
Cell reports 42(11), 113330 (2023) [10.1016/j.celrep.2023.113330]
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Public Biological Databases and the Sui Generis Database Right
International review of intellectual property and competition law 54, 1316?1358 (2023) [10.1007/s40319-023-01373-0]
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AIRR community curation and standardised representation for immunoglobulin and T cell receptor germline sets.
ImmunoInformatics 10, 100025 (2023) [10.1016/j.immuno.2023.100025]
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Author Correction: Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model.
npj vaccines 8(1), 86 (2023) [10.1038/s41541-023-00687-x]
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Molecular and functional properties of human Plasmodium falciparum CSP C?terminus antibodies
EMBO molecular medicine 15(6), e17454 (2023) [10.15252/emmm.202317454]
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Glycosylated nanoparticle-based PfCSP vaccine confers long-lasting antibody responses and sterile protection in mouse malaria model.
npj vaccines 8(1), 52 (2023) [10.1038/s41541-023-00653-7]
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Progress in vaccine development for infectious diseases-a Keystone Symposia report.
Annals of the New York Academy of Sciences 1524, 65-86 (2023) [10.1111/nyas.14975]
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High-density binding to Plasmodium falciparum circumsporozoite protein repeats by inhibitory antibody elicited in mouse with human immunoglobulin repertoire.
PLoS pathogens 18(11), e1010999 - (2022) [10.1371/journal.ppat.1010999]
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Sterilizing immunity: Understanding COVID-19.
Immunity 55(12), 2231-2235 (2022) [10.1016/j.immuni.2022.10.017]
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MDA-LDL vaccination induces athero-protective germinal-center-derived antibody responses.
Cell reports 41(2), 111468 (2022) [10.1016/j.celrep.2022.111468]
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Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria.
Nature Communications 13(1), 4098 (2022) [10.1038/s41467-022-31640-6]
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A BALB/c IGHV Reference Set, Defined by Haplotype Analysis of Long-Read VDJ-C Sequences From F1 (BALB/c x C57BL/6) Mice.
Frontiers in immunology 13, 888555 (2022) [10.3389/fimmu.2022.888555]
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Clonal evolution and TCR specificity of the human TFH cell response to Plasmodium falciparum CSP.
Science immunology 7(72), eabm9644 (2022) [10.1126/sciimmunol.abm9644]
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Adaptive Immune Receptor Repertoire (AIRR) Community Guide to TR and IG Gene Annotation.
Methods in molecular biology 2453, 279-296 (2022) [10.1007/978-1-0716-2115-8_16]
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Data Sharing and Reuse: A Method by the AIRR Community.
Methods in molecular biology 2453, 447-476 (2022) [10.1007/978-1-0716-2115-8_23]
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How to induce protective humoral immunity against Plasmodium falciparum circumsporozoite protein.
Journal of experimental medicine 219(2), e20201313 (2022) [10.1084/jem.20201313]
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An efficient single-cell based method for linking human T cell phenotype to T cell receptor sequence and specificity.
European journal of immunology 52(2), 237-246 (2022) [10.1002/eji.202149392]
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Parallelism of intestinal secretory IgA shapes functional microbial fitness.
Nature <London> 598(7882), 657-661 (2021) [10.1038/s41586-021-03973-7]
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From Multiplex Serology to Serolomics-A Novel Approach to the Antibody Response against the SARS-CoV-2 Proteome.
Viruses 13(5), 749 (2021) [10.3390/v13050749]
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Molecular Dynamics Simulations in Drug Discovery and Pharmaceutical Development
Processes 9(1), 71 (2021) [10.3390/pr9010071]
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ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies.
Nature <London> 589(7841), 287-292 (2021) [10.1038/s41586-020-2993-2]
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The ADC API: A Web API for the Programmatic Query of the AIRR Data Commons.
Frontiers in Big Data 3, 22 (2020) [10.3389/fdata.2020.00022]
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An environment for sustainable research software in Germany and beyond: current state, open challenges, and call for action.
F1000Research 9, 295 (2020) [10.12688/f1000research.23224.1]
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The Effect of Force-Field Parameters on Cytochrome P450-Membrane Interactions: Structure and Dynamics.
Scientific reports 10(1), 7284 (2020) [10.1038/s41598-020-64129-7]
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Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs
Nature medicine 26(7), 1135 - 1145 (2020) [10.1038/s41591-020-0881-9]
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A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity
Journal of experimental medicine 217(11), e20200061 (2020) [10.1084/jem.20200061]
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High microbiota reactivity of adult human intestinal IgA requires somatic mutations.
Journal of experimental medicine 217(11), e20200275 (2020) [10.1084/jem.20200275]
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Find and follow your passion.
Nature immunology 21(3), 237 (2020) [10.1038/s41590-020-0613-9]
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Erratum to: Repertoire and Neutralizing Activity of Antibodies Against Hepatitis C Virus E2 Peptide in Patients With Spontaneous Resolution of Hepatitis C.
The journal of infectious diseases 221(12), 2084 (2020) [10.1093/infdis/jiaa052]
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IGLV3-21*01 is an inherited risk factor for CLL through the acquisition of a single-point mutation enabling autonomous BCR signaling.
Proceedings of the National Academy of Sciences of the United States of America 117(8), 4320-4327 (2020) [10.1073/pnas.1913810117]
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Human IgA binds a diverse array of commensal bacteria.
Journal of experimental medicine 217(3), e20181635 (2020) [10.1084/jem.20181635]
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OGRDB: a reference database of inferred immune receptor genes.
Nucleic acids research 48(D1), D964-D970 (2020) [10.1093/nar/gkz822]
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A Proposed New Nomenclature for the Immunoglobulin Genes of Mus musculus
Frontiers in immunology 10, 2961 (2019) [10.3389/fimmu.2019.02961]
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Retraction: Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition.
Journal of experimental medicine 216(1), 245 - 245 (2019) [10.1084/jem.2012148612112018r]
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Differing Membrane Interactions of Two Highly Similar Drug-Metabolizing Cytochrome P450 Isoforms: CYP 2C9 and CYP 2C19.
International journal of molecular sciences 20(18), 4328 (2019) [10.3390/ijms20184328]
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Antibodies against Plasmodium falciparum malaria at the molecular level.
Nature reviews / Immunology Immunology [...] 19(12), 761-775 (2019) [10.1038/s41577-019-0209-5]
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A comparison of immunoglobulin IGHV, IGHD and IGHJ genes in wild-derived and classical inbred mouse strains.
Immunology & cell biology 97(10), 888-901 (2019) [10.1111/imcb.12288]
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Expression Cloning of Antibodies from Single Human B Cells.
Methods in molecular biology 1956, 105-125 (2019) [10.1007/978-1-4939-9151-8_5]
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Repertoire and neutralizing activity of antibodies against E2 peptide in patients with spontaneous resolution of hepatitis C.
The journal of infectious diseases 220(7), 1209-1218 (2019) [10.1093/infdis/jiz274]
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High-throughput single-cell sequencing of paired TCR? and TCR? genes for the direct expression-cloning and functional analysis of murine T-cell receptors.
European journal of immunology 49(8), 1269-1277 (2019) [10.1002/eji.201848030]
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HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells.
Cell reports 27(2), 572 - 585.e7 (2019) [10.1016/j.celrep.2019.03.032]
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N-Methyl-D-Aspartate Receptor Dysfunction by Unmutated Human Antibodies Against the NR1 Subunit.
Annals of neurology 85(5), 771-776 (2019) [10.1002/ana.25460]
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Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming.
Frontiers in immunology 10, 435 (2019) [10.3389/fimmu.2019.00435]
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Differences in Self-Recognition between Secreted Antibody and Membrane-Bound B Cell Antigen Receptor.
The journal of immunology 202(5), 1417 - 1427 (2019) [10.4049/jimmunol.1800690]
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From human antibody structure and function towards the design of a novel Plasmodium falciparum circumsporozoite protein malaria vaccine.
Current opinion in immunology 53, 119 - 123 (2018) [10.1016/j.coi.2018.04.023]
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AIRR Community Standardized Representations for Annotated Immune Repertoires
Frontiers in immunology 9, 2206 (2018) [10.3389/fimmu.2018.02206]
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Assessing human B cell repertoire diversity and convergence.
Immunological reviews 284(1), 51 - 66 (2018) [10.1111/imr.12670]
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Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.
Science 360(6395), 1358 - 1362 (2018) [10.1126/science.aar5304]
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Cross-specificity of protective human antibodies against Klebsiella pneumoniae LPS O-antigen.
Nature immunology 19(6), 617 - 624 (2018) [10.1038/s41590-018-0106-2]
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A Functional General Stress Response of Bradyrhizobium diazoefficiens Is Required for Early Stages of Host Plant Infection.
Molecular plant microbe interactions 31(5), 537 - 547 (2018) [10.1094/MPMI-11-17-0284-R]
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Clonal selection drives protective memory B cell responses in controlled human malaria infection.
Science immunology 3(20), eaap8029 - (2018) [10.1126/sciimmunol.aap8029]
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Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.
Journal of experimental medicine 215(1), 63 - 75 (2018) [10.1084/jem.20170869]
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Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity 47(6), 1197 - 1209.e10 (2017) [10.1016/j.immuni.2017.11.007]
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Adaptive Immune Receptor Repertoire Community recommendations for sharing immune-repertoire sequencing data.
Nature immunology 18(12), 1274 - 1278 (2017) [10.1038/ni.3873]
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Reproducibility and Reuse of Adaptive Immune Receptor Repertoire Data
Frontiers in immunology 8, 1418 (2017) [10.3389/fimmu.2017.01418]
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Novel Approaches to Analyze Immunoglobulin Repertoires.
Trends in immunology 38(7), 471 - 482 (2017) [10.1016/j.it.2017.05.003]
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Comment on 'A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data'.
The journal of immunology 198(9), 3371-3373 (2017)
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Reply: In vitro effects of a human monoclonal antibody against the N-methyl-d-aspartate receptor.
Brain 140(Pt 2), e10 - e10 (2017) [10.1093/brain/aww290]
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Human isotype-dependent inhibitory antibody responses against Mycobacterium tuberculosis.
EMBO molecular medicine 8(11), 1325 - 1339 (2016) [10.15252/emmm.201606330]
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Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.
Brain 139(Pt 10), 2641 - 2652 (2016) [10.1093/brain/aww208]
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sciReptor: analysis of single-cell level immunoglobulin repertoires.
BMC bioinformatics 17(1), 67 (2016) [10.1186/s12859-016-0920-1]
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Direct high-throughput amplification and sequencing of immunoglobulin genes from single human B cells.
European journal of immunology 45(9), 2698 - 2700 (2015) [10.1002/eji.201545526]
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Dickkopf-3 acts as a modulator of B cell fate and function.
The journal of immunology 194(6), 2624 - 2634 (2015) [10.4049/jimmunol.1402160]
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Tuning the phase of circadian entrainment.
Interface 12(108), 20150282 - (2015) [10.1098/rsif.2015.0282]
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