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Smoking Cessation in Old Age: Less Heart Attacks and Strokes Within Only Five Years

No. 12 | 20/02/2013 | by KT/Sel

Smokers increase their risk of myocardial infarction (heart attack) and stroke with every cigarette they smoke. Conversely, those who quit smoking even at an advanced age will have a considerable decrease in their risk after a very short time. Scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) published their results in the European Journal of Epidemiology.

© dkfz.de

Professor Hermann Brenner and colleagues analyzed the data of 8.807 individuals aged between 50 and 74 years using data of Saarland citizens. “We were able to show that the risk of smokers for cardiovascular diseases is more than twice that of non-smokers. However, former smokers are affected at almost the same low rate as people of the same age who never smoked,” says Brenner. “Moreover, smokers are affected at a significantly younger age than individuals who have never smoked or have stopped smoking.” For example, a 60-year-old smoker has the same risk of myocardial infarction as a 79-year-old non-smoker and the same risk of stroke as a 69-year-old non-smoker. Dose and duration of tobacco consumption also have an impact on disease risk. The more cigarettes a smoker consumes per day over a prolonged period of time, the higher his or her risk raises.

The study shows that the positive effect of smoking cessation becomes noticeable within a short period of time. “Compared to individuals who continue smoking, the risk of myocardial infarction and stroke is reduced by more than 40 percent already within the first five years after the last cigarette,” says Carolin Gellert, first author of the study. The results suggest that smoking cessation programs, which have concentrated on younger participants up to now, should be expanded to reach out to older people as well.

Last year, Hermann Brenner and his colleagues had already studied the impact of smoking on the overall mortality of people beyond the age of 60. They had used data from international studies without German participation. In their latest study, they have evaluated data from the so-called ESTHER Study whose participants are from Saarland, a state of Germany. They included those individuals who had not suffered a heart attack or stroke prior to study start and whose health status had been surveyed for up to ten years afterwards. In their evaluation, the scientists also took account of the effects of other factors such as age, gender, alcohol consumption, education and physical exercise as well as blood pressure, diabetes, cholesterol levels, body height and weight.

Carolin Gellert, Ben Schöttker, Heiko Müller, Bernd Holleczek, Hermann Brenner: Impact of smoking and quitting on cardiovascular outcomes and risk advancement periods among older adults.
Eur J Epidemiol. 2013. doi: 10.1007/s10654-013-9776-0.

With more than 3,000 employees, the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) is Germany’s largest biomedical research institute. DKFZ scientists identify cancer risk factors, investigate how cancer progresses and develop new cancer prevention strategies. They are also developing new methods to diagnose tumors more precisely and treat cancer patients more successfully. The DKFZ's Cancer Information Service (KID) provides patients, interested citizens and experts with individual answers to questions relating to cancer.

To transfer promising approaches from cancer research to the clinic and thus improve the prognosis of cancer patients, the DKFZ cooperates with excellent research institutions and university hospitals throughout Germany:

  • National Center for Tumor Diseases (NCT, 6 sites)
  • German Cancer Consortium (DKTK, 8 sites)
  • Hopp Children's Cancer Center (KiTZ) Heidelberg
  • Helmholtz Institute for Translational Oncology (HI-TRON Mainz) - A Helmholtz Institute of the DKFZ
  • DKFZ-Hector Cancer Institute at the University Medical Center Mannheim
  • National Cancer Prevention Center (jointly with German Cancer Aid)
The DKFZ is 90 percent financed by the Federal Ministry of Education and Research and 10 percent by the state of Baden-Württemberg. The DKFZ is a member of the Helmholtz Association of German Research Centers.

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